James W Hodge

Author PubWeight™ 79.52‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy. J Exp Med 2006 4.84
2 Immunologic and prognostic factors associated with overall survival employing a poxviral-based PSA vaccine in metastatic castrate-resistant prostate cancer. Cancer Immunol Immunother 2009 3.70
3 Combining a recombinant cancer vaccine with standard definitive radiotherapy in patients with localized prostate cancer. Clin Cancer Res 2005 3.57
4 Phase I study of sequential vaccinations with fowlpox-CEA(6D)-TRICOM alone and sequentially with vaccinia-CEA(6D)-TRICOM, with and without granulocyte-macrophage colony-stimulating factor, in patients with carcinoembryonic antigen-expressing carcinomas. J Clin Oncol 2004 3.11
5 External beam radiation of tumors alters phenotype of tumor cells to render them susceptible to vaccine-mediated T-cell killing. Cancer Res 2004 2.91
6 Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes. Cancer Res 2004 2.54
7 Irradiation of tumor cells up-regulates Fas and enhances CTL lytic activity and CTL adoptive immunotherapy. J Immunol 2003 2.51
8 Combination of docetaxel and recombinant vaccine enhances T-cell responses and antitumor activity: effects of docetaxel on immune enhancement. Clin Cancer Res 2008 1.83
9 Vector-based vaccine/cytokine combination therapy to enhance induction of immune responses to a self-antigen and antitumor activity. Cancer Res 2002 1.77
10 Prostvac-VF: a vector-based vaccine targeting PSA in prostate cancer. Expert Opin Investig Drugs 2009 1.71
11 Pilot study of vaccination with recombinant CEA-MUC-1-TRICOM poxviral-based vaccines in patients with metastatic carcinoma. Clin Cancer Res 2008 1.59
12 Induction of an antigen cascade by diversified subcutaneous/intratumoral vaccination is associated with antitumor responses. Clin Cancer Res 2005 1.49
13 Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing. Oncotarget 2014 1.49
14 In the field: exploiting the untapped potential of immunogenic modulation by radiation in combination with immunotherapy for the treatment of cancer. Front Oncol 2012 1.43
15 Combination chemotherapy and radiation of human squamous cell carcinoma of the head and neck augments CTL-mediated lysis. Clin Cancer Res 2006 1.36
16 Selective induction of high avidity CTL by altering the balance of signals from APC. J Immunol 2003 1.34
17 Consequence of dose scheduling of sunitinib on host immune response elements and vaccine combination therapy. Int J Cancer 2011 1.34
18 The requirement of multimodal therapy (vaccine, local tumor radiation, and reduction of suppressor cells) to eliminate established tumors. Clin Cancer Res 2005 1.20
19 Exploitation of differential homeostatic proliferation of T-cell subsets following chemotherapy to enhance the efficacy of vaccine-mediated antitumor responses. Cancer Immunol Immunother 2011 1.18
20 Combining radiation, immunotherapy, and antiangiogenesis agents in the management of cancer: the Three Musketeers or just another quixotic combination? Mol Biosyst 2009 1.16
21 Immune impact induced by PROSTVAC (PSA-TRICOM), a therapeutic vaccine for prostate cancer. Cancer Immunol Res 2013 1.16
22 Combination therapy with a second-generation androgen receptor antagonist and a metastasis vaccine improves survival in a spontaneous prostate cancer model. Clin Cancer Res 2013 1.15
23 The use of chelated radionuclide (samarium-153-ethylenediaminetetramethylenephosphonate) to modulate phenotype of tumor cells and enhance T cell-mediated killing. Clin Cancer Res 2008 1.14
24 Combination therapy with local radiofrequency ablation and systemic vaccine enhances antitumor immunity and mediates local and distal tumor regression. PLoS One 2013 1.14
25 Vaccines with enhanced costimulation maintain high avidity memory CTL. J Immunol 2005 1.12
26 Vaccination with a recombinant Saccharomyces cerevisiae expressing a tumor antigen breaks immune tolerance and elicits therapeutic antitumor responses. Clin Cancer Res 2008 1.09
27 Preclinical and clinical studies of recombinant poxvirus vaccines for carcinoma therapy. Crit Rev Immunol 2007 1.07
28 Identification of an interferon-gamma-inducible carcinoembryonic antigen (CEA) CD8(+) T-cell epitope, which mediates tumor killing in CEA transgenic mice. Cancer Res 2002 1.04
29 Recombinant Saccharomyces cerevisiae (yeast-CEA) as a potent activator of murine dendritic cells. Vaccine 2007 1.04
30 Combining radiation and immunotherapy for synergistic antitumor therapy. Curr Opin Mol Ther 2009 1.03
31 4-1BB ligand enhances tumor-specific immunity of poxvirus vaccines. Vaccine 2006 1.02
32 Soluble CD27-pool in humans may contribute to T cell activation and tumor immunity. J Immunol 2013 1.01
33 Effect of a small molecule BCL-2 inhibitor on immune function and use with a recombinant vaccine. Int J Cancer 2010 1.00
34 Amplification of the lytic potential of effector/memory CD8+ cells by vector-based enhancement of ICAM-1 (CD54) in target cells: implications for intratumoral vaccine therapy. Cancer Gene Ther 2004 0.98
35 Concurrent vaccination with two distinct vaccine platforms targeting the same antigen generates phenotypically and functionally distinct T-cell populations. Cancer Immunol Immunother 2009 0.98
36 Immunological targeting of tumor cells undergoing an epithelial-mesenchymal transition via a recombinant brachyury-yeast vaccine. Oncotarget 2013 0.98
37 Cancer vaccines: preclinical studies and novel strategies. Adv Cancer Res 2006 0.96
38 Use of radiolabeled monoclonal antibody to enhance vaccine-mediated antitumor effects. Cancer Immunol Immunother 2008 0.96
39 Defining molecular signature of pro-immunogenic radiotherapy targets in human prostate cancer cells. Radiat Res 2014 0.95
40 Radiation-induced modulation of costimulatory and coinhibitory T-cell signaling molecules on human prostate carcinoma cells promotes productive antitumor immune interactions. Cancer Biother Radiopharm 2014 0.95
41 Serum antibodies to blood group A predict survival on PROSTVAC-VF. Clin Cancer Res 2013 0.92
42 Cancer vaccines targeting carcinoembryonic antigen: state-of-the-art and future promise. Expert Rev Vaccines 2013 0.91
43 Vaccines based on whole recombinant Saccharomyces cerevisiae cells. FEMS Yeast Res 2010 0.91
44 Humoral response to a viral glycan correlates with survival on PROSTVAC-VF. Proc Natl Acad Sci U S A 2014 0.91
45 Intratumoral vaccination and diversified subcutaneous/ intratumoral vaccination with recombinant poxviruses encoding a tumor antigen and multiple costimulatory molecules. Clin Cancer Res 2004 0.90
46 Unlocking the combination: potentiation of radiation-induced antitumor responses with immunotherapy. Radiat Res 2014 0.90
47 The combined activation of positive costimulatory signals with modulation of a negative costimulatory signal for the enhancement of vaccine-mediated T-cell responses. Cancer Immunol Immunother 2007 0.89
48 Combination therapy of an orthotopic renal cell carcinoma model using intratumoral vector-mediated costimulation and systemic interleukin-2. Clin Cancer Res 2007 0.88
49 TRICOM vector based cancer vaccines. Curr Pharm Des 2006 0.87
50 A recombinant vector expressing transgenes for four T-cell costimulatory molecules (OX40L, B7-1, ICAM-1, LFA-3) induces sustained CD4+ and CD8+ T-cell activation, protection from apoptosis, and enhanced cytokine production. Cell Immunol 2003 0.86
51 Vaccines as monotherapy and in combination therapy for prostate cancer. Clin Transl Sci 2010 0.85
52 Synergistic antitumor activity of immune strategies combined with radiation. Front Biosci 2007 0.85
53 Potential approach to immunotherapy of chronic lymphocytic leukemia (CLL): enhanced immunogenicity of CLL cells via infection with vectors encoding for multiple costimulatory molecules. Blood 2005 0.85
54 Defining the molecular signature of chemotherapy-mediated lung tumor phenotype modulation and increased susceptibility to T-cell killing. Cancer Biother Radiopharm 2012 0.84
55 Harnessing the potential of radiation-induced immune modulation for cancer therapy. Cancer Immunol Res 2013 0.84
56 Enhancing immune responses to tumor-associated antigens. Cancer Biol Ther 2009 0.84
57 Immunobiology of radiotherapy: new paradigms. Radiat Res 2014 0.84
58 Combining Vaccines with Conventional Therapies for Cancer. Update Cancer Ther 2007 0.82
59 In vivo effects of lattice radiation therapy on local and distant lung cancer: potential role of immunomodulation. Radiat Res 2014 0.82
60 Vaccine-mediated immunotherapy directed against a transcription factor driving the metastatic process. Cancer Res 2014 0.81
61 Intratumoral delivery of vector mediated IL-2 in combination with vaccine results in enhanced T cell avidity and anti-tumor activity. Cancer Immunol Immunother 2007 0.77
62 Introduction: Therapeutic cancer vaccines. Semin Oncol 2012 0.75