Published in J Allergy Clin Immunol on February 01, 2006
Atopic dermatitis: a disease of altered skin barrier and immune dysregulation. Immunol Rev (2011) 2.62
Recent insights into atopic dermatitis and implications for management of infectious complications. J Allergy Clin Immunol (2010) 2.20
Basis for the barrier abnormality in atopic dermatitis: outside-inside-outside pathogenic mechanisms. J Allergy Clin Immunol (2008) 2.11
Th2 Cytokines and Atopic Dermatitis. J Clin Cell Immunol (2011) 1.91
Frontiers in pruritus research: scratching the brain for more effective itch therapy. J Clin Invest (2006) 1.90
Chronic pruritus: a paraneoplastic sign. Dermatol Ther (2010) 1.50
Abnormal skin barrier in the etiopathogenesis of atopic dermatitis. Curr Opin Allergy Clin Immunol (2009) 1.43
The ion channel TRPA1 is required for chronic itch. J Neurosci (2013) 1.41
IL-31-Driven Skin Remodeling Involves Epidermal Cell Proliferation and Thickening That Lead to Impaired Skin-Barrier Function. PLoS One (2016) 1.39
IL-31-IL-31R interactions negatively regulate type 2 inflammation in the lung. J Exp Med (2007) 1.34
Neural processing of itch. Neuroscience (2013) 1.32
A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: Involvement of TRPV1 and TRPA1. J Allergy Clin Immunol (2013) 1.18
Structures and biological functions of IL-31 and IL-31 receptors. Cytokine Growth Factor Rev (2008) 1.14
Oncostatin M receptor-beta mutations underlie familial primary localized cutaneous amyloidosis. Am J Hum Genet (2008) 1.10
Comprehensive RNA-Seq expression analysis of sensory ganglia with a focus on ion channels and GPCRs in Trigeminal ganglia. PLoS One (2013) 1.06
New drugs targeting Th2 lymphocytes in asthma. J Occup Med Toxicol (2008) 1.03
Role of stem cell factor and bone marrow-derived fibroblasts in airway remodeling. Am J Pathol (2009) 1.02
The enigmatic cytokine oncostatin m and roles in disease. ISRN Inflamm (2013) 1.01
Therapeutic Implications of a Barrier-based Pathogenesis of Atopic Dermatitis. Ann Dermatol (2010) 1.00
The infectious aspects of atopic dermatitis. Immunol Allergy Clin North Am (2010) 0.98
Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity. Elife (2014) 0.98
Basic mechanisms of itch. Clin Exp Allergy (2011) 0.98
New insights into the mechanisms of itch: are pain and itch controlled by distinct mechanisms? Pflugers Arch (2013) 0.97
Cytokines and the skin barrier. Int J Mol Sci (2013) 0.96
New insights into the pathophysiology and treatment of chronic itch in patients with end-stage renal disease, chronic liver disease, and lymphoma. Int J Dermatol (2010) 0.95
IL-31 Serum Protein and Tissue mRNA Levels in Patients with Atopic Dermatitis. Ann Dermatol (2011) 0.95
Novel IL31RA gene mutation and ancestral OSMR mutant allele in familial primary cutaneous amyloidosis. Eur J Hum Genet (2010) 0.95
Chronic pruritus: clinics and treatment. Ann Dermatol (2011) 0.94
gp130 cytokines are positive signals triggering changes in gene expression and axon outgrowth in peripheral neurons following injury. Front Mol Neurosci (2012) 0.93
Critical role for mast cell Stat5 activity in skin inflammation. Cell Rep (2014) 0.93
Therapy of pruritus. Expert Opin Pharmacother (2010) 0.93
Activation of eosinophils interacting with dermal fibroblasts by pruritogenic cytokine IL-31 and alarmin IL-33: implications in atopic dermatitis. PLoS One (2012) 0.92
Therapeutic implications of a barrier-based pathogenesis of atopic dermatitis. Clin Rev Allergy Immunol (2011) 0.91
Analysis of the Potential Topical Anti-Inflammatory Activity of Averrhoa carambola L. in Mice. Evid Based Complement Alternat Med (2011) 0.90
Management of itch in atopic dermatitis. Semin Cutan Med Surg (2011) 0.89
The itchy scalp--scratching for an explanation. Exp Dermatol (2011) 0.88
International Union of Basic and Clinical Pharmacology. XCVIII. Histamine Receptors. Pharmacol Rev (2015) 0.88
Definition and characterization of an inhibitor for interleukin-31. J Biol Chem (2010) 0.88
IL-31-IL-31R interactions limit the magnitude of Th2 cytokine-dependent immunity and inflammation following intestinal helminth infection. J Immunol (2009) 0.88
Skin barrier function. Curr Allergy Asthma Rep (2008) 0.88
TRPA1-dependent pruritus in IL-13-induced chronic atopic dermatitis. J Immunol (2013) 0.87
Dendritic cells activated by IFN-γ/STAT1 express IL-31 receptor and release proinflammatory mediators upon IL-31 treatment. J Immunol (2012) 0.86
Identifying Polymorphisms in IL-31 and Their Association with Susceptibility to Asthma. Korean J Pathol (2012) 0.85
Regulation of myeloid progenitor cell proliferation/survival by IL-31 receptor and IL-31. Exp Hematol (2007) 0.84
Genetic and epigenetic studies of atopic dermatitis. Allergy Asthma Clin Immunol (2016) 0.83
A new itch to scratch for TSLP. Trends Immunol (2014) 0.83
Targeted treatment of pruritus: a look into the future. Br J Dermatol (2011) 0.83
Lipid abnormalities and lipid-based repair strategies in atopic dermatitis. Biochim Biophys Acta (2013) 0.82
Th2 Cytokines Augment IL-31/IL-31RA Interactions via STAT6-dependent IL-31RA Expression. J Biol Chem (2015) 0.82
Relationship between serum 25-hydroxyvitamin D and interleukin-31 levels, and the severity of atopic dermatitis in children. Korean J Pediatr (2015) 0.82
Role of IL-31 in regulation of Th2 cytokine levels in patients with nasal polyps. Eur Arch Otorhinolaryngol (2014) 0.81
Systematic identification and characterization of novel human skin-associated genes encoding membrane and secreted proteins. PLoS One (2013) 0.81
The Transforming Growth Factor β1/Interleukin-31 Pathway Is Upregulated in Patients with Hepatitis B Virus-Related Acute-on-Chronic Liver Failure and Is Associated with Disease Severity and Survival. Clin Vaccine Immunol (2015) 0.81
IL-31 associated with coronary artery lesion formation in Kawasaki disease. PLoS One (2014) 0.81
Mechanistic correlations between two itch biomarkers, cytokine interleukin-31 and neuropeptide β-endorphin, via STAT3/calcium axis in atopic dermatitis. Br J Dermatol (2012) 0.81
Neuroimmunological mechanism of pruritus in atopic dermatitis focused on the role of serotonin. Biomol Ther (Seoul) (2012) 0.80
Anti-IL-31 receptor antibody is shown to be a potential therapeutic option for treating itch and dermatitis in mice. Br J Pharmacol (2014) 0.79
Atopic dermatitis in children: clinical features, pathophysiology, and treatment. Immunol Allergy Clin North Am (2014) 0.79
Understanding the pathophysiology of itch. Dermatol Ther (2013) 0.78
Improved pruritus correlates with lower levels of IL-31 in CTCL patients under different therapeutic modalities. Clin Immunol (2015) 0.78
25-Hydroxyvitamin D, IL-31, and IL-33 in children with allergic disease of the airways. Mediators Inflamm (2014) 0.78
Role of Interleukin-2 in Uremic Pruritus Among Attendants of AL-Zahraa Hospital Dialysis Unit. Indian J Dermatol (2015) 0.78
Narrow band ultraviolet B irradiations cause alteration in interleukin-31 serum level in psoriatic patients. Arch Dermatol Res (2012) 0.78
Topical therapies for pruritus. Semin Cutan Med Surg (2011) 0.78
Pathological mechanisms of skin homing T cells in atopic dermatitis. World Allergy Organ J (2010) 0.78
IL-31 is overexpressed in lichen planus but its level does not correlate with pruritus severity. J Immunol Res (2015) 0.77
Rise of the sensors: nociception and pruritus. Curr Allergy Asthma Rep (2012) 0.77
Recent advances in pruritus - what we have learned and where are we headed. F1000 Med Rep (2010) 0.77
Expression and function of histamine and its receptors in atopic dermatitis. Mol Cell Pediatr (2015) 0.77
The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction. Nat Commun (2017) 0.77
The interleukin (IL)-31/IL-31R axis contributes to tumor growth in human follicular lymphoma. Leukemia (2014) 0.77
Molecular dissection of human interleukin-31-mediated signal transduction through site-directed mutagenesis. J Biol Chem (2009) 0.77
Mechanism of Sleep Disturbance in Children with Atopic Dermatitis and the Role of the Circadian Rhythm and Melatonin. Int J Mol Sci (2016) 0.76
High-intensity swimming exercise increases dust mite extract and 1-chloro-2,4-dinitrobenzene-derived atopic dermatitis in BALB/c mice. Inflammation (2014) 0.76
Molecular Mechanisms of Cutaneous Inflammatory Disorder: Atopic Dermatitis. Int J Mol Sci (2016) 0.76
The Pathogenetic Effect of Natural and Bacterial Toxins on Atopic Dermatitis. Toxins (Basel) (2016) 0.76
Increased levels of interleukin 31 (IL-31) in osteoporosis. BMC Immunol (2015) 0.76
Pruritus Reduction with Systemic Anti-lymphoma Treatments in Patients with Cutaneous T Cell Lymphoma: A Narrative Review. Dermatol Ther (Heidelb) (2016) 0.75
The release of IL-31 and IL-13 after nasal allergen challenge and their relation to nasal symptoms. Clin Transl Allergy (2012) 0.75
IL-31-induced pruritus in dogs: a novel experimental model to evaluate anti-pruritic effects of canine therapeutics. Vet Dermatol (2015) 0.75
Differential Changes in the Peptidergic and the Non-Peptidergic Skin Innervation in Rat Models for Inflammation, Dry Skin Itch, and Dermatitis. J Invest Dermatol (2015) 0.75
Mediators of pruritus in lichen planus. Autoimmune Dis (2013) 0.75
Sézary Syndrome and Atopic Dermatitis: Comparison of Immunological Aspects and Targets. Biomed Res Int (2016) 0.75
Oral ketotifen and topical antibiotic therapy in the management of pruritus in prurigo nodularis: a randomized, controlled, single-blind, parallel study. Indian J Dermatol (2013) 0.75
Therapeutic Effects of Korean Red Ginseng Extract in a Murine Model of Atopic Dermatitis: Anti-pruritic and Anti-inflammatory Mechanism. J Korean Med Sci (2017) 0.75
IL-31 Induces Chemotaxis, Calcium Mobilization, Release of Reactive Oxygen Species, and CCL26 in Eosinophils, Which Are Capable to Release IL-31. J Invest Dermatol (2015) 0.75
Itching sensation in psoriatic patients and its relation to body mass index and IL-17 and IL-31 concentrations. Postepy Dermatol Alergol (2015) 0.75
Possible Role of Interleukin-31/33 Axis in Imatinib Mesylate-Associated Skin Toxicity. Turk J Haematol (2015) 0.75
Environmental risk factors and their role in the management of atopic dermatitis. Expert Rev Clin Immunol (2016) 0.75
Treatment of plaque psoriasis with an ointment formulation of the Janus kinase inhibitor, tofacitinib: a Phase 2b randomized clinical trial. BMC Dermatol (2016) 0.75
The association of interleukin-31 polymorphisms with interleukin-31 serum levels and risk of systemic lupus erythematosus. Rheumatol Int (2016) 0.75
Inflammatory and Noninflammatory Itch: Implications in Pathophysiology-Directed Treatments. Int J Mol Sci (2017) 0.75
The Role of Intereukin-31 in Pathogenesis of Itch and Its Intensity in a Course of Bullous Pemphigoid and Dermatitis Herpetiformis. Biomed Res Int (2017) 0.75
Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide. Nature (2007) 8.88
Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus. Sci Transl Med (2011) 5.60
A randomized trial of icatibant in ACE-inhibitor-induced angioedema. N Engl J Med (2015) 4.75
Lyme borreliosis. Lancet Infect Dis (2003) 4.58
Characterization of a common susceptibility locus for asthma-related traits. Science (2004) 4.05
Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production. J Exp Med (2005) 4.04
CCL27-CCR10 interactions regulate T cell-mediated skin inflammation. Nat Med (2002) 4.02
MicroRNAs: novel regulators involved in the pathogenesis of psoriasis? PLoS One (2007) 3.96
Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis. N Engl J Med (2013) 3.81
Gene expression profiles distinguish idiopathic pulmonary fibrosis from hypersensitivity pneumonitis. Am J Respir Crit Care Med (2005) 3.72
IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells. J Exp Med (2007) 3.66
Gene expression analyses reveal molecular relationships among 20 regions of the human CNS. Neurogenetics (2006) 3.40
MicroRNAs and immunity: novel players in the regulation of normal immune function and inflammation. Semin Cancer Biol (2008) 3.32
The neurobiology of itch. Nat Rev Neurosci (2006) 3.25
Icatibant, a new bradykinin-receptor antagonist, in hereditary angioedema. N Engl J Med (2010) 2.98
Maintenance and polarization of human TH2 central memory T cells by thymic stromal lymphopoietin-activated dendritic cells. Immunity (2006) 2.95
Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon-independent apoptosis in human melanoma cells. J Clin Invest (2009) 2.85
Adverse effects of topical glucocorticosteroids. J Am Acad Dermatol (2006) 2.80
Combined analysis of HPV-DNA, p16 and EGFR expression to predict prognosis in oropharyngeal cancer. Int J Cancer (2007) 2.75
Chemokines: agents for the immunotherapy of cancer? Nat Rev Immunol (2002) 2.68
Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8. J Exp Med (2009) 2.66
Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies. Mol Med (2010) 2.51
The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia. Cancer Cell (2009) 2.42
Environmental biodiversity, human microbiota, and allergy are interrelated. Proc Natl Acad Sci U S A (2012) 2.41
Neuronal control of skin function: the skin as a neuroimmunoendocrine organ. Physiol Rev (2006) 2.30
The human antimicrobial peptide LL-37 suppresses apoptosis in keratinocytes. J Invest Dermatol (2008) 2.23
Severe cutaneous reaction during radiation therapy with concurrent cetuximab. N Engl J Med (2007) 2.19
Neonatal blue-light phototherapy could increase the risk of dysplastic nevus development. Pediatrics (2007) 2.16
International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors. Pharmacol Rev (2013) 2.11
Role for protease activity in visceral pain in irritable bowel syndrome. J Clin Invest (2007) 2.09
Cytokines and chemokines orchestrate atopic skin inflammation. J Allergy Clin Immunol (2006) 2.08
Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance. J Clin Invest (2010) 2.02
Homeostatic chemokine receptors and organ-specific metastasis. Nat Rev Immunol (2011) 1.98
Propionibacterium acnes and lipopolysaccharide induce the expression of antimicrobial peptides and proinflammatory cytokines/chemokines in human sebocytes. Microbes Infect (2006) 1.91
Profound coordinated alterations of intratumoral NK cell phenotype and function in lung carcinoma. Cancer Res (2011) 1.91
Frontiers in pruritus research: scratching the brain for more effective itch therapy. J Clin Invest (2006) 1.90
Evidence for epithelial-mesenchymal transition in cancer stem cells of head and neck squamous cell carcinoma. PLoS One (2011) 1.87
Chemokine/chemokine receptor nomenclature. J Interferon Cytokine Res (2002) 1.86
Plasmacytoid dendritic cells sense skin injury and promote wound healing through type I interferons. J Exp Med (2010) 1.85
Accumulation of apoptotic cells in the epidermis of patients with cutaneous lupus erythematosus after ultraviolet irradiation. Arthritis Rheum (2006) 1.83
Update on Kaposi's sarcoma and other HHV8 associated diseases. Part 1: epidemiology, environmental predispositions, clinical manifestations, and therapy. Lancet Infect Dis (2002) 1.80
Sleep restriction increases the risk of developing cardiovascular diseases by augmenting proinflammatory responses through IL-17 and CRP. PLoS One (2009) 1.80
Hemese, a hemocyte-specific transmembrane protein, affects the cellular immune response in Drosophila. Proc Natl Acad Sci U S A (2003) 1.79
Loss-of-function mutations in the keratin 5 gene lead to Dowling-Degos disease. Am J Hum Genet (2006) 1.78
Distinct strains of Propionibacterium acnes induce selective human beta-defensin-2 and interleukin-8 expression in human keratinocytes through toll-like receptors. J Invest Dermatol (2005) 1.76
The distinct roles of two GPCRs, MrgprC11 and PAR2, in itch and hyperalgesia. Sci Signal (2011) 1.75
Treatment of cutaneous leishmaniasis by photodynamic therapy. J Am Acad Dermatol (2003) 1.75
Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions. Sci Transl Med (2011) 1.74
CCR3 is essential for skin eosinophilia and airway hyperresponsiveness in a murine model of allergic skin inflammation. J Clin Invest (2002) 1.73
Efficacy and safety of tacrolimus ointment compared with that of hydrocortisone acetate ointment in children with atopic dermatitis. J Allergy Clin Immunol (2002) 1.71
IgG4-related autoimmune diseases: Polymorphous presentation complicates diagnosis and treatment. Dtsch Arztebl Int (2015) 1.70
Evaluation of protease-activated receptor 2 in murine models of arthritis. Arthritis Rheum (2007) 1.70
Epidermal EGFR controls cutaneous host defense and prevents inflammation. Sci Transl Med (2013) 1.69
(1,3)-beta-glucans activate both dectin-1 and NLRP3 inflammasome in human macrophages. J Immunol (2010) 1.67
"Outside-to-inside" (and now back to "outside") pathogenic mechanisms in atopic dermatitis. J Invest Dermatol (2008) 1.64
Altered microRNA expression of nasal mucosa in long-term asthma and allergic rhinitis. Int Arch Allergy Immunol (2014) 1.64
The inducible CXCR3 ligands control plasmacytoid dendritic cell responsiveness to the constitutive chemokine stromal cell-derived factor 1 (SDF-1)/CXCL12. J Exp Med (2003) 1.63
Characterization of chemokines and adhesion molecules associated with T cell presence in tertiary lymphoid structures in human lung cancer. Cancer Res (2011) 1.63
Long, needle-like carbon nanotubes and asbestos activate the NLRP3 inflammasome through a similar mechanism. ACS Nano (2011) 1.62
A comparison of oral methylprednisolone plus azathioprine or mycophenolate mofetil for the treatment of bullous pemphigoid. Arch Dermatol (2007) 1.59
Therapy for severe necrotizing vasculitis with infliximab. J Am Acad Dermatol (2004) 1.59
Tumor immune escape by the loss of homeostatic chemokine expression. Proc Natl Acad Sci U S A (2007) 1.58
Epigenetic silencing of the PTEN gene in melanoma. Cancer Res (2006) 1.58
Density of Demodex folliculorum in patients receiving epidermal growth factor receptor inhibitors. Dermatology (2011) 1.57
Effects of RNA degradation on gene expression analysis of human postmortem tissues. FASEB J (2005) 1.55
Early T cell signalling is reversibly altered in PD-1+ T lymphocytes infiltrating human tumors. PLoS One (2011) 1.55
Pyoderma gangrenosum, acne, and suppurative hidradenitis (PASH)--a new autoinflammatory syndrome distinct from PAPA syndrome. J Am Acad Dermatol (2011) 1.55
Polymorphonuclear granulocytes in human head and neck cancer: enhanced inflammatory activity, modulation by cancer cells and expansion in advanced disease. Int J Cancer (2011) 1.55
Dendritic cells in tumor-associated tertiary lymphoid structures signal a Th1 cytotoxic immune contexture and license the positive prognostic value of infiltrating CD8+ T cells. Cancer Res (2013) 1.54
The mouse S100A15 ortholog parallels genomic organization, structure, gene expression, and protein-processing pattern of the human S100A7/A15 subfamily during epidermal maturation. J Invest Dermatol (2006) 1.53
Expression of vanilloid receptor subtype 1 in cutaneous sensory nerve fibers, mast cells, and epithelial cells of appendage structures. Exp Dermatol (2004) 1.52
Absence of CCR4 exacerbates skin inflammation in an oxazolone-induced contact hypersensitivity model. J Invest Dermatol (2010) 1.51
Protein phosphatase 2A mediates resensitization of the neurokinin 1 receptor. Am J Physiol Cell Physiol (2011) 1.51
Frequent alterations of Ras signaling pathway genes in sporadic malignant melanomas. Int J Cancer (2004) 1.50
MYCN-regulated microRNAs repress estrogen receptor-alpha (ESR1) expression and neuronal differentiation in human neuroblastoma. Proc Natl Acad Sci U S A (2010) 1.49
Toll-like receptor activation during cutaneous allergen sensitization blocks development of asthma through IFN-gamma-dependent mechanisms. J Invest Dermatol (2012) 1.48
Loss of DNA mismatch repair proteins in skin tumors from patients with Muir-Torre syndrome and MSH2 or MLH1 germline mutations: establishment of immunohistochemical analysis as a screening test. Am J Surg Pathol (2002) 1.48
The dire consequences of doping. Lancet (2008) 1.46
microRNAs in inflammation. Int Rev Immunol (2009) 1.45
Sequential involvement of CCR2 and CCR6 ligands for immature dendritic cell recruitment: possible role at inflamed epithelial surfaces. Eur J Immunol (2002) 1.44
IgE-mediated allergy to fungal allergens in Finland with special reference to Alternaria alternata and Cladosporium herbarum. Ann Allergy Asthma Immunol (2003) 1.44
First use of a computer-assisted operator-controlled flexible endoscope for transoral surgery. Laryngoscope (2014) 1.44
Tumor-derived matrix metalloproteinase-1 targets endothelial proteinase-activated receptor 1 promoting endothelial cell activation. Cancer Res (2006) 1.42