Kazuhiro Imai

Author PubWeight™ 68.08‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Decreased serum levels of D-serine in patients with schizophrenia: evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia. Arch Gen Psychiatry 2003 1.93
2 Prediction of strength and strain of the proximal femur by a CT-based finite element method. J Biomech 2006 1.53
3 Intraoperative sentinel lymph node mapping using a new sterilizable magnetometer in patients with nonsmall cell lung cancer. Ann Thorac Surg 2006 1.47
4 Clinical and immunologic evaluation of dendritic cell-based immunotherapy in combination with gemcitabine and/or S-1 in patients with advanced pancreatic carcinoma. Pancreas 2012 1.12
5 Tumor-derived TGFbeta-1 induces dendritic cell apoptosis in the sentinel lymph node. J Immunol 2006 1.07
6 Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure--possible involvement of nitric oxide and asymmetric NG, NG-dimethylarginine. Circ J 2005 1.02
7 First fluorescent photoinduced electron transfer (PET) reagent for hydroperoxides. Org Lett 2003 0.97
8 Simultaneous determination of D- and L-serine in rat brain microdialysis sample using a column-switching HPLC with fluorimetric detection. Biomed Chromatogr 2004 0.95
9 Expression of the chemokine receptor CXCR4 correlates with a favorable prognosis in patients with adenocarcinoma of the lung. Lung Cancer 2009 0.93
10 A proteomics method revealing disease-related proteins in livers of hepatitis-infected mouse model. J Proteome Res 2007 0.92
11 A fully automated amino acid analyzer using NBD-F as a fluorescent derivatization reagent. Biomed Chromatogr 2004 0.90
12 Prediction of vertebral strength under loading conditions occurring in activities of daily living using a computed tomography-based nonlinear finite element method. Spine (Phila Pa 1976) 2009 0.89
13 Fluorescence enhancement by hydroperoxides based on a change in the intramolecular charge transfer character of benzofurazan. Chem Commun (Camb) 2005 0.88
14 Limitation of immunoaffinity column for the removal of abundant proteins from plasma in quantitative plasma proteomics. Biomed Chromatogr 2009 0.88
15 Comprehensive fluorogenic derivatization-liquid chromatography/tandem mass spectrometry proteomic analysis of colorectal cancer cell to identify biomarker candidate. Biomed Chromatogr 2012 0.87
16 Determination of fluoxetine enantiomers in rat plasma by pre-column fluorescence derivatization and column-switching high-performance liquid chromatography. Analyst 2002 0.85
17 Development of an HPLC-fluorescence determination method for carboxylic acids related to the tricarboxylic acid cycle as a metabolome tool. Biomed Chromatogr 2005 0.85
18 Inhibition of Hsp90 and 70 sensitizes melanoma cells to hyperthermia using ferromagnetic particles with a low Curie temperature. Int J Clin Oncol 2013 0.85
19 Possible role of D-serine in the pathophysiology of Alzheimer's disease. Prog Neuropsychopharmacol Biol Psychiatry 2004 0.85
20 Suppression of Zinc Finger Homeobox 3 expression in tumor cells decreases the survival rate among non-small cell lung cancer patients. Cancer Biomark 2012 0.84
21 Proteomics of Caenorhabditis elegans over-expressing human alpha-synuclein analyzed by fluorogenic derivatization-liquid chromatography/tandem mass spectrometry: identification of actin and several ribosomal proteins as negative markers at early Parkinson's disease stages. Biomed Chromatogr 2008 0.83
22 Synthesis of benzofurazan derivatization reagents for carboxylic acids and its application to analysis of fatty acids in rat plasma by high-performance liquid chromatography-electrospray ionization mass spectrometry. Biomed Chromatogr 2005 0.83
23 Intraoperative detection of lymph node micrometastasis with flow cytometry in non-small cell lung cancer. J Thorac Cardiovasc Surg 2005 0.82
24 Determination of serum D-lactic and L-lactic acids in normal subjects and diabetic patients by column-switching HPLC with pre-column fluorescence derivatization. Anal Bioanal Chem 2003 0.82
25 REG1A expression status suggests chemosensitivity among advanced thoracic esophageal squamous cell carcinoma patients treated with esophagectomy followed by adjuvant chemotherapy. Ann Surg Oncol 2013 0.81
26 Determination of fluoxetine and norfluoxetine in rat plasma by HPLC with pre-column derivatization and fluorescence detection. Biomed Chromatogr 2003 0.81
27 Strong expression of cyclin B2 mRNA correlates with a poor prognosis in patients with non-small cell lung cancer. Tumour Biol 2013 0.81
28 Estrogen receptor binding assay method for endocrine disruptors using fluorescence polarization. Anal Chem 2002 0.81
29 Recent progress in the development of derivatization reagents having a benzofurazan structure. Biomed Chromatogr 2008 0.81
30 Precision, limit of detection and range of quantitation in competitive ELISA. Anal Chem 2004 0.80
31 The CRP 1846T/T genotype is associated with a poor prognosis in patients with non-small cell lung cancer. Tumour Biol 2010 0.80
32 A study of the relationship between the chemical structures and the fluorescence quantum yields of coumarins, quinoxalinones and benzoxazinones for the development of sensitive fluorescent derivatization reagents. Photochem Photobiol Sci 2003 0.80
33 Low catechol-O-methyltransferase activity in the brain and blood pressure regulation. Biol Pharm Bull 2006 0.80
34 Achromatically injection-seeded terahertz-wave parametric generator. Opt Lett 2002 0.80
35 Development of hydrophilic fluorogenic derivatization reagents for thiols: 4-(N-acetylaminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole and 4-(N-trichloroacetylaminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole. J Chromatogr A 2002 0.80
36 Determination of kynurenine levels in rat plasma by high-performance liquid chromatography with pre-column fluorescence derivatization. Anal Chim Acta 2006 0.80
37 REG Iα activates c-Jun through MAPK pathways to enhance the radiosensitivity of squamous esophageal cancer cells. Tumour Biol 2015 0.79
38 Effect of vascularity on canine distracted tibial callus consolidation. Clin Orthop Relat Res 2005 0.79
39 Alterations of plasma and cerebrospinal fluid glutamate levels in rats treated with the N-methyl-D-aspartate receptor antagonist, ketamine. Biomed Chromatogr 2006 0.79
40 An expression of within-plate uncertainty in sandwich ELISA. J Pharm Biomed Anal 2004 0.79
41 High-performance liquid chromatography-fluorescent assay of catechol-O-methyltransferase activity in rat brain. Anal Bioanal Chem 2003 0.79
42 An HPLC assay of hydroxyl radicals by the hydroxylation reaction of terephthalic acid. Biomed Chromatogr 2004 0.79
43 A photoinduced electron-transfer reagent for peroxyacetic acid, 4-ethylthioacetylamino-7-phenylsulfonyl-2,1,3-benzoxadiazole, based on the method for predicting the fluorescence quantum yields. Anal Chem 2002 0.79
44 An FD-LC-MS/MS proteomic strategy for revealing cellular protein networks: a conditional superoxide dismutase 1 knockout cells. PLoS One 2012 0.78
45 Pulmonary function after lobectomy versus segmentectomy in patients with stage I non-small cell lung cancer. World J Surg 2014 0.78
46 Synthesis and evaluation of a fluorogenic reagent for proteomic studies: 7-fluoro-N-[2-(dimethylamino)ethyl]-2,1,3-benzoxadiazole-4-sulfonamide (DAABD-F). Analyst 2010 0.78
47 Preparation and in vivo evaluation of a water-soluble prodrug for 2R-gamma-tocotrienol and as a two-step prodrug for 2,7,8-trimethyl-2S-(beta-carboxyethyl)-6-hydroxychroman (S-gamma-CEHC) in rat. Drug Metab Dispos 2007 0.78
48 Application of an improved proteomics method, fluorogenic derivatization-liquid chromatography-tandem mass spectrometry, to differential analysis of proteins in small regions of mouse brain. J Chromatogr A 2008 0.78
49 Development of 7-(N,N-dimethylaminosulfonyl)-5-N-(4-N-aminoethyl)piperazino-2,1,3-benzoxadiazole as a water-soluble fluorogenic reagent for the sensitive liquid chromatographic determination of saturated carboxylic acids. Analyst 2002 0.78
50 A trial proteomics fingerprint analysis of HepaRG cells by FD-LC-MS/MS. Analyst 2015 0.78
51 Evaluation of postoperative pregabalin for attenuation of postoperative shoulder pain after thoracotomy in patients with lung cancer, a preliminary result. Gen Thorac Cardiovasc Surg 2014 0.78
52 Improved assay for catechol-O-methyltransferase activity utilizing norepinephrine as an enzymatic substrate and reversed-phase high-performance liquid chromatography with fluorescence detection. J Chromatogr A 2005 0.78
53 Intravenous administration of 2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxy chroman (gamma-CEHC) to rats and determination of its plasma concentration and urinary sodium excretion. Biomed Chromatogr 2004 0.78
54 Distraction osteogenesis promotes angiogenesis in the surrounding muscles. Clin Orthop Relat Res 2007 0.78
55 Assay of catechol-O-methyltransferase activity in human erythrocytes using norepinephrine as a natural substrate. Ann Clin Biochem 2002 0.78
56 Acquired xanthine dehydrogenase expression shortens survival in patients with resected adenocarcinoma of lung. Tumour Biol 2012 0.78
57 Synthesis of the isotope-labeled derivatization reagent for carboxylic acids, 7-(N,N-dimethylaminosulfonyl)-4-(aminoethyl)piperazino-2,1,3-benzoxadiazole (d6) [DBD-PZ-NH2 (D)], and its application to the quantification and the determination of relative amount of fatty acids in rat plasma samples by high-performance liquid chromatography/mass spectrometry. Biomed Chromatogr 2006 0.78
58 C-reactive protein reduces the relative number of tumor-associated M2 macrophages and intratumoral angiogenesis in mice. Tohoku J Exp Med 2014 0.77
59 Determination of insulin in a single islet of Langerhans by high-performance liquid chromatography with fluorescence detection. Anal Chem 2002 0.77
60 Study on interactions of endocrine disruptors with estrogen receptor-beta using fluorescence polarization. Anal Sci 2003 0.77
61 Suppression of thiol exchange reaction in the determination of reduced-form thiols by high-performance liquid chromatography with fluorescence detection after derivatization with fluorogenic benzofurazan reagent, 7-fluoro-2,1,3-benzoxadiazole-4-sulfonate and 4-aminosulfonyl-7-fluoro-2,1,3-benzoxadiazole. Biomed Chromatogr 2006 0.77
62 Enantioselective determination of 3-hydroxybutyrate in the tissues of normal and streptozotocin-induced diabetic rats of different ages. J Chromatogr B Analyt Technol Biomed Life Sci 2011 0.77
63 A method to evaluate the renin-angiotensin system in rat renal cortex using a microdialysis technique combined with HPLC-fluorescence detection. Anal Chem 2002 0.77
64 Cell density inversely regulates D- and L-aspartate levels in rat pheochromocytoma MPT1 cells. Arch Biochem Biophys 2002 0.77
65 Novel d-gamma-tocopherol derivative as a prodrug for d-gamma-tocopherol and a two-step prodrug for S-gamma-CEHC. J Lipid Res 2002 0.77
66 Toxicoproteomic analysis of a mouse model of nonsteroidal anti-inflammatory drug-induced gastric ulcers. Biochem Biophys Res Commun 2012 0.77
67 Application of fluorogenic derivatization-liquid chromatography-tandem mass spectrometric proteome method to skeletal muscle proteins in fast Thoroughbred horses. J Proteome Res 2009 0.77
68 A toxicoproteomic study on cardioprotective effects of pre-administration of docetaxel in a mouse model of adriamycin-induced cardiotoxicity. Biochem Pharmacol 2010 0.77
69 Study on interactions of endocrine disruptors with estrogen receptor using fluorescence polarization. Analyst 2003 0.77
70 Rat liver and kidney catechol-O-methyltransferase activity measured by high-performance liquid chromatography with fluorescence detection. Biomed Chromatogr 2002 0.77
71 L-Glutamate in the extracellular space regulates endogenous D-aspartate homeostasis in rat pheochromocytoma MPT1 cells. Arch Biochem Biophys 2004 0.76
72 Rapid assay for catechol-O-methyltransferase activity by high-performance liquid chromatography-fluorescence detection. J Chromatogr B Analyt Technol Biomed Life Sci 2005 0.76
73 Development of a column-switching high-performance liquid chromatography for kynurenine enantiomers and its application to a pharmacokinetic study in rat plasma. Anal Chim Acta 2007 0.76
74 Enumeration of bacterial cell numbers by amplified firefly bioluminescence without cultivation. Anal Biochem 2003 0.76
75 Fluorogenic derivatization reagents suitable for isolation and identification of cysteine-containing proteins utilizing high-performance liquid chromatography-tandem mass spectrometry. Anal Chem 2004 0.76
76 Alteration of intracellular secretory acute phase response proteins expressed in human hepatocyte induced by exposure with interleukin-6. Cytokine 2012 0.76
77 High-performance liquid chromatographic assay of N(G)-monomethyl-L-arginine, N(G),N(G)-dimethyl-L-arginine, and N(G),N(G)'-dimethyl-L-arginine using 4-fluoro-7-nitro-2, 1,3-benzoxadiazole as a fluorescent reagent. J Chromatogr A 2005 0.76
78 An automated analyzer for methylated arginines in rat plasma by high-performance liquid chromatography with post-column fluorescence reaction. Analyst 2002 0.76
79 Esophageal Cancer Patients Have a High Incidence of Severe Periodontitis and Preoperative Dental Care Reduces the Likelihood of Severe Pneumonia after Esophagectomy. Dig Surg 2016 0.76
80 Fluorescence determination of N-acetylaspartic acid in the rat cerebrum homogenate using high-performance liquid chromatography with pre-column fluorescence derivatization. Biomed Chromatogr 2008 0.76
81 Efficient chromatographic separation of intact proteins derivatized with a fluorogenic reagent for proteomics analysis. Biomed Chromatogr 2013 0.76
82 Improved separation of fluorogenic derivatized intact proteins with high resolution and efficiency using a reversed-phase liquid chromatographic system. Biomed Chromatogr 2014 0.75
83 Liquid chromatographic separation of proteins derivatized with a fluorogenic reagent at cysteinyl residues on a non-porous column for differential proteomics analysis. J Chromatogr A 2011 0.75
84 Existence of low-molecular-weight thiols in Caenorhabditis elegans demonstrated by HPLC-fluorescene detection utilizing 7-chloro-N-[2-(dimethylamino)ethyl]-2,1,3-benzoxadiazole-4-sulfonamide. Biomed Chromatogr 2007 0.75
85 Synthesis of benzofurazan derivatization reagents for short chain carboxylic acids in liquid chromatography/electrospray ionization-tandem mass spectrometry (LC/ESI-MS/MS). Biomed Chromatogr 2009 0.75
86 Proteome analysis of altered proteins in streptozotocin-induced diabetic rat kidney using the fluorogenic derivatization-liquid chromatography-tandem mass spectrometry method. Biomed Chromatogr 2012 0.75
87 Synthesis of benzofurazan derivatization reagents for carboxylic acids in liquid chromatography/electrospray ionization-tandem mass spectrometry. Biomed Chromatogr 2007 0.75
88 Synthesis of 4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-N-methylhydrazino-2,1,3-benzoxadiazole (DAABD-MHz) as a derivatization reagent for aldehydes in liquid chromatography/electrospray ionization-tandem mass spectrometry. Biomed Chromatogr 2008 0.75
89 The effects of spacer length on the fluorescence quantum yields of the benzofurazan compounds bearing a donor-acceptor system. Luminescence 2002 0.75
90 FD-LC-MS/MS method for determining protein expression and elucidating biochemical events in tissues and cells. Biol Pharm Bull 2012 0.75
91 Cationic starch derivatives as dynamic coating additives for protein analysis in capillary electrophoresis. J Chromatogr A 2005 0.75
92 [Estimation of precision in system suitability tests]. Yakugaku Zasshi 2002 0.75
93 [Precision of internal standard method in HPLC analysis]. Yakugaku Zasshi 2003 0.75
94 High performance liquid chromatography post-column chemiluminescence determination of sulfonamide residues in milk at low concentration levels using bis[4-nitro-2-(3,6,9-trioxadecyloxycarbonyl)phenyl] oxalate as chemiluminescent reagent. J Chromatogr A 2005 0.75
95 Subcutaneous tendon rupture of extensor tendons on bilateral wrists associated with calcium pyrophosphate dihydrate crystal deposition disease. Mod Rheumatol 2007 0.75
96 Recent progress in derivatization methods for LC and CE analysis. J Pharm Biomed Anal 2003 0.75
97 An improved method for proteomics studies in C. elegans by fluorogenic derivatization, HPLC isolation, enzymatic digestion and liquid chromatography--tandem mass spectrometric identification. Biomed Chromatogr 2005 0.75
98 Screening system for D-Asp-containing proteins using D-aspartyl endopeptidase and two-dimensional gel electrophoresis. Amino Acids 2008 0.75
99 An automated fluorescence protein sequencer using 7-methylthio-4-(2,1,3-benzoxadiazolyl) isothiocyanate (MTBD-NCS) as an Edman reagent. Biomed Chromatogr 2002 0.75
100 Synthesis and evaluation of fluorogenic reagents for simultaneous detection of peptides and proteins by HPLC in two different samples. Biomed Chromatogr 2006 0.75
101 Late-onset chylothorax after pulmonary resection for lung cancer. Gen Thorac Cardiovasc Surg 2011 0.75
102 An assay for determination of rat adrenal catechol-O-methyltransferase activity: comparison of spontaneously hypertensive rats and Wistar-Kyoto rats. Anal Bioanal Chem 2004 0.75
103 Determination of rat blood S-D-lactoylglutathione by a column-switching high-performance liquid chromatography with precolumn fluorescence derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole. Anal Biochem 2004 0.75
104 Study of the acute cardiovascular effects of several antihypertensive agents with the measurement of plasma catecholamines in mice. Anal Bioanal Chem 2009 0.75
105 A further study on the combined use of internal standard and isotope-labeled derivatization reagent for expansion of linear dynamic ranges in liquid chromatography-electrospray mass spectrometry. Biomed Chromatogr 2006 0.75
106 Fluorescence on-off switching mechanism of benzofurazans. Org Biomol Chem 2003 0.75
107 Design and synthesis of a hydrophilic fluorescent derivatization reagent for carboxylic acids, 4-N-(4-N-aminoethyl)piperazino-7-nitro-2,1,3-benzoxadiazole (NBD-PZ-NH2), and its application to capillary electrophoresis with laser-induced fluorescence detection. Biomed Chromatogr 2002 0.75
108 [A case of complete resection of non-squamous non-small-cell lung cancer after induction chemotherapy using carboplatin, paclitaxel, and bevacizumab]. Gan To Kagaku Ryoho 2012 0.75
109 Comprehensive and temporal analysis of secreted proteins in the medium from IL-6 exposed human hepatocyte. Biomed Chromatogr 2014 0.75
110 Evaluation of the potential for lymph node metastasis using CRP 1846C>T genetic polymorphism in invasive breast cancer. Tumour Biol 2014 0.75
111 Simultaneous determination of 3,4-dihydroxyphenylacetic acid and homovanillic acid using high performance liquid chromatography-fluorescence detection and application to rat kidney microdialysate. Anal Biochem 2002 0.75
112 Altered expression of insulins I and II and their mRNAs in the islets of Langerhans in dexamethasone-induced diabetic rats. Biomed Chromatogr 2003 0.75
113 Oxidative stress increases 6-nitronorepinephrine and 6-nitroepinephrine concentrations in rat brain. Biomed Chromatogr 2008 0.75
114 Detection limit estimated from slope of calibration curve: an application to competitive ELISA. Anal Sci 2005 0.75
115 Hoarseness caused by arytenoid dislocation after surgery for lung cancer. Gen Thorac Cardiovasc Surg 2013 0.75
116 Determination of nitrocatecholamines in rat brain using high-performance liquid chromatography-peroxyoxalate chemiluminescence reaction detection. J Chromatogr A 2007 0.75
117 Quantification of norepinephrine and its metabolites in the plasma of renal failure models. Nephron Physiol 2010 0.75
118 Capillary electrophoresis with laser induced-fluorescence detection of profens derivatized with the water-soluble fluorogenic reagent 4-N-(4-N'-aminoethyl)piperazino-7-nitro-2,1,3-benzoxadiazole. J Chromatogr A 2003 0.75
119 Catecholamine analysis with microcolumn LC-peroxyoxalate chemiluminescence reaction detection. Clin Chim Acta 2005 0.75
120 Reduced membrane-bound catechol-O-methyltransferase in the liver of spontaneously hypertensive rats. Hypertens Res 2003 0.75
121 An identification method for altered proteins in tissues utilizing fluorescence derivatization, liquid chromatography, tandem mass spectrometry, and a database-searching algorithm. Anal Chem 2003 0.75
122 A rapid assay method for catechol-O-methyltransferase activity by flow injection analysis. Biomed Chromatogr 2002 0.75
123 [Estimation of detection limit from slope of B/B0 in competitive ELISA]. Yakugaku Zasshi 2005 0.75
124 [Development and application of FD-LC-MS/MS proteomics analysis revealing protein expression and biochemical events in tissues and cells]. Yakugaku Zasshi 2015 0.75
125 [Prediction of bone strength using a quantitative computed tomography based finite element method]. Clin Calcium 2011 0.75