PubRank

Pavel Majer

Author PubWeight™ 16.59‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 High-affinity near-infrared fluorescent small-molecule contrast agents for in vivo imaging of prostate-specific membrane antigen. Mol Imaging 2005 1.97
2 Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer. EMBO J 2006 1.55
3 Synthesis and biological evaluation of D-amino acid oxidase inhibitors. J Med Chem 2008 1.29
4 Glutamate carboxypeptidase II inhibition protects motor neurons from death in familial amyotrophic lateral sclerosis models. Proc Natl Acad Sci U S A 2003 1.18
5 Substrate specificity, inhibition and enzymological analysis of recombinant human glutamate carboxypeptidase II. J Neurochem 2002 1.17
6 Structural insight into the pharmacophore pocket of human glutamate carboxypeptidase II. J Med Chem 2007 1.08
7 Structural basis of interactions between human glutamate carboxypeptidase II and its substrate analogs. J Mol Biol 2008 1.01
8 Biochemical characterization of human glutamate carboxypeptidase III. J Neurochem 2007 0.98
9 Mouse brain serine racemase catalyzes specific elimination of L-serine to pyruvate. FEBS Lett 2003 0.88
10 Amino acids at the N- and C-termini of human glutamate carboxypeptidase II are required for enzymatic activity and proper folding. Eur J Biochem 2004 0.87
11 Enantiospecificity of glutamate carboxypeptidase II inhibition. J Med Chem 2005 0.86
12 Homology modeling and SAR analysis of Schistosoma japonicum cathepsin D (SjCD) with statin inhibitors identify a unique active site steric barrier with potential for the design of specific inhibitors. Biol Chem 2005 0.83
13 The discovery and structure-activity relationships of indole-based inhibitors of glutamate carboxypeptidase II. Bioorg Med Chem Lett 2010 0.79
14 Facile synthesis of alpha-substituted acrylate esters. J Org Chem 2002 0.78
15 δ-Thiolactones as prodrugs of thiol-based glutamate carboxypeptidase II (GCPII) inhibitors. J Med Chem 2013 0.76
16 An ethylenamine inhibitor binds tightly to both wild type and mutant HIV-1 proteases. Structure and energy study. J Med Chem 2003 0.76
17 Structure-based specificity mapping of secreted aspartic proteases of Candida parapsilosis, Candida albicans, and Candida tropicalis using peptidomimetic inhibitors and homology modeling. Biol Chem 2006 0.75
18 Sphinganine-like biogenesis of (E)-1-nitropentadec-1-ene in termite soldiers of the genus Prorhinotermes. Chembiochem 2014 0.75