Published in Curr Pharm Des on January 01, 2006
Antioxidant therapy in Alzheimer's disease: theory and practice. Mini Rev Med Chem (2008) 1.00
A molecular study of pathways involved in the inhibition of cell proliferation in neuroblastoma B65 cells by the GSK-3 inhibitors lithium and SB-415286. J Cell Mol Med (2008) 0.89
Link between cancer and Alzheimer disease via oxidative stress induced by nitric oxide-dependent mitochondrial DNA overproliferation and deletion. Oxid Med Cell Longev (2013) 0.84
Premature centromere division of the X chromosome in neurons in Alzheimer's disease. J Neurochem (2008) 0.83
The involvement of cell cycle events in the pathogenesis of Alzheimer's disease. Alzheimers Res Ther (2010) 0.80
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution. Genome Res (2005) 8.38
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. J Neurosci (2009) 3.77
Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins. Proc Natl Acad Sci U S A (2008) 3.68
AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons. J Clin Invest (2007) 3.32
The role of insulin receptor substrate 2 in hypothalamic and beta cell function. J Clin Invest (2005) 2.40
Oxidative stress and neurotoxicity. Chem Res Toxicol (2007) 2.12
Vesicular stomatitis virus-based ebola vaccine is well-tolerated and protects immunocompromised nonhuman primates. PLoS Pathog (2008) 2.10
Most reported genetic associations with general intelligence are probably false positives. Psychol Sci (2012) 2.10
Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients. Am J Pathol (2008) 2.09
Neural circuit involved in idiopathic infantile nystagmus syndrome based on FMRI. J Pediatr Ophthalmol Strabismus (2011) 2.02
Amyloid-beta: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-beta. Brain Res Brain Res Rev (2003) 1.97
Involvement of oxidative stress in Alzheimer disease. J Neuropathol Exp Neurol (2006) 1.92
Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence. Biochemistry (2003) 1.89
Overexpression of the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) in skeletal muscle repatterns energy metabolism in the mouse. J Biol Chem (2007) 1.85
Oxidative stress increases expression and activity of BACE in NT2 neurons. Neurobiol Dis (2002) 1.85
Alzheimer's disease: the two-hit hypothesis. Lancet Neurol (2004) 1.81
Iron, zinc and copper in the Alzheimer's disease brain: a quantitative meta-analysis. Some insight on the influence of citation bias on scientific opinion. Prog Neurobiol (2011) 1.80
A randomized trial of a low-trapping nonselective N-methyl-D-aspartate channel blocker in major depression. Biol Psychiatry (2012) 1.76
Subcellular and metabolic examination of amyloid-beta peptides in Alzheimer disease pathogenesis: evidence for Abeta(25-35). Exp Neurol (2009) 1.75
Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease. Free Radic Biol Med (2012) 1.67
The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. J Neurochem (2009) 1.67
Variably protease-sensitive prionopathy: a new sporadic disease of the prion protein. Ann Neurol (2010) 1.66
Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology. Biochim Biophys Acta (2009) 1.66
The Promises and Pitfalls of Genoeconomics* Annu Rev Econom (2012) 1.66
Microtubule reduction in Alzheimer's disease and aging is independent of tau filament formation. Am J Pathol (2003) 1.66
Diabetes-induced nitrative stress in the retina, and correction by aminoguanidine. J Neurochem (2002) 1.65
Alzheimer disease. Dis Mon (2010) 1.64
Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. J Biol Chem (2005) 1.61
Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein. J Neurochem (2007) 1.61
Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons. Cell Metab (2009) 1.59
Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease. J Neurochem (2011) 1.57
The role of mitogen-activated protein kinase pathways in Alzheimer's disease. Neurosignals (2003) 1.56
LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1. Hum Mol Genet (2012) 1.56
Alzheimer disease, the two-hit hypothesis: an update. Biochim Biophys Acta (2006) 1.56
A new model of oxidative stress in rat pups. Neonatology (2008) 1.55
Impaired regulation of synaptic strength in hippocampal neurons from GluR1-deficient mice. J Physiol (2003) 1.55
Development of an acute and highly pathogenic nonhuman primate model of Nipah virus infection. PLoS One (2010) 1.54
The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules. J Neurosci Res (2008) 1.54
Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment. J Alzheimers Dis (2010) 1.54
Chitin-like polysaccharides in Alzheimer's disease brains. Curr Alzheimer Res (2005) 1.51
Abnormal mitochondrial dynamics and neurodegenerative diseases. Biochim Biophys Acta (2009) 1.49
Challenging the amyloid cascade hypothesis: senile plaques and amyloid-beta as protective adaptations to Alzheimer disease. Ann N Y Acad Sci (2004) 1.49
Pet-1 is required across different stages of life to regulate serotonergic function. Nat Neurosci (2010) 1.48
Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins. FASEB J (2002) 1.47
Cell cycle proteins in Alzheimer's disease: plenty of wheels but no cycle. J Alzheimers Dis (2002) 1.47
Selective thyroid hormone receptor-beta activation: a strategy for reduction of weight, cholesterol, and lipoprotein (a) with reduced cardiovascular liability. Proc Natl Acad Sci U S A (2003) 1.46
4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal. Chem Res Toxicol (2005) 1.46
Oxidative stress in Alzheimer disease: a possibility for prevention. Neuropharmacology (2010) 1.46
Nucleic acid oxidation in Alzheimer disease. Free Radic Biol Med (2008) 1.45
Alzheimer disease pathology as a host response. J Neuropathol Exp Neurol (2008) 1.45
Labeling of cerebral amyloid beta deposits in vivo using intranasal basic fibroblast growth factor and serum amyloid P component in mice. J Nucl Med (2002) 1.44