Published in Curr Top Microbiol Immunol on January 01, 2005
Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells. J Immunol (2010) 9.72
Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros. Nat Immunol (2008) 2.40
Ikaros and Aiolos inhibit pre-B-cell proliferation by directly suppressing c-Myc expression. Mol Cell Biol (2010) 1.42
Helios is associated with CD4 T cells differentiating to T helper 2 and follicular helper T cells in vivo independently of Foxp3 expression. PLoS One (2011) 1.06
FoxO1 induces Ikaros splicing to promote immunoglobulin gene recombination. J Exp Med (2012) 0.97
Transcriptional regulation of the Ikzf1 locus. Blood (2013) 0.97
Philadelphia chromosome-positive acute lymphoblastic leukemia. Hematol Oncol Clin North Am (2009) 0.95
How B cells influence bone biology in health and disease. Bone (2010) 0.94
Helios transcription factor expression depends on Gsx2 and Dlx1&2 function in developing striatal matrix neurons. Stem Cells Dev (2012) 0.87
The combined expression patterns of Ikaros isoforms characterize different hematological tumor subtypes. PLoS One (2013) 0.82
Ikaros: the enhancer makes the difference. Blood (2013) 0.80
An Ikaros Promoter Element with Dual Epigenetic and Transcriptional Activities. PLoS One (2015) 0.75
Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science (1999) 8.63
Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin. Cell (1997) 5.62
DNA sequence requirements for transcriptional initiator activity in mammalian cells. Mol Cell Biol (1994) 3.76
Multiple control elements mediate activation of the murine and human interleukin 12 p40 promoters: evidence of functional synergy between C/EBP and Rel proteins. Mol Cell Biol (1997) 3.70
T-antigen-DNA polymerase alpha complex implicated in simian virus 40 DNA replication. Mol Cell Biol (1986) 3.22
Transcription of herpes simplex virus tk sequences under the control of wild-type and mutant human RNA polymerase I promoters. Mol Cell Biol (1985) 2.92
Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding. Genes Dev (2000) 2.55
Direct recognition of initiator elements by a component of the transcription factor IID complex. Genes Dev (1994) 2.41
LyF-1, a transcriptional regulator that interacts with a novel class of promoters for lymphocyte-specific genes. Mol Cell Biol (1991) 2.41
Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin. Genes Dev (1998) 2.37
Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages. Proc Natl Acad Sci U S A (2000) 2.36
Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event. Nat Immunol (2001) 2.34
Pioneer factors, genetic competence, and inductive signaling: programming liver and pancreas progenitors from the endoderm. Cold Spring Harb Symp Quant Biol (2008) 2.34
Regulation of human ribosomal RNA transcription. Proc Natl Acad Sci U S A (1983) 2.25
Rapid and selective remodeling of a positioned nucleosome during the induction of IL-12 p40 transcription. Immunity (1999) 2.24
Roles of TATA and initiator elements in determining the start site location and direction of RNA polymerase II transcription. J Biol Chem (1992) 2.24
Two distinct promoter elements in the human rRNA gene identified by linker scanning mutagenesis. Mol Cell Biol (1986) 2.09
The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene. Mol Cell Biol (1994) 1.99
Hematopoietic stem cells and lymphoid progenitors express different Ikaros isoforms, and Ikaros is localized to heterochromatin in immature lymphocytes. Proc Natl Acad Sci U S A (1998) 1.98
A prominent role for Sp1 during lipopolysaccharide-mediated induction of the IL-10 promoter in macrophages. J Immunol (2000) 1.90
Core promoter specificities of the Sp1 and VP16 transcriptional activation domains. Mol Cell Biol (1995) 1.68
Similar mechanisms for transcription initiation mediated through a TATA box or an initiator element. J Biol Chem (1992) 1.67
Generality of a functional initiator consensus sequence. Gene (1996) 1.65
Mechanism of initiator-mediated transcription: evidence for a functional interaction between the TATA-binding protein and DNA in the absence of a specific recognition sequence. Mol Cell Biol (1993) 1.63
Combinatorial regulation of transcription II: The immunoglobulin mu heavy chain gene. Immunity (1995) 1.33
CIF, an essential cofactor for TFIID-dependent initiator function. Genes Dev (1996) 1.30
Down-regulation of TDT transcription in CD4(+)CD8(+) thymocytes by Ikaros proteins in direct competition with an Ets activator. Genes Dev (2001) 1.24
Mechanism of synergy between TATA and initiator: synergistic binding of TFIID following a putative TFIIA-induced isomerization. Genes Dev (1997) 1.21
Transcription of the lymphocyte-specific terminal deoxynucleotidyltransferase gene requires a specific core promoter structure. Proc Natl Acad Sci U S A (1996) 1.17
HIV-1 core promoter lacks a simple initiator element but contains a bipartite activator at the transcription start site. J Biol Chem (1993) 1.13
CIF150, a human cofactor for transcription factor IID-dependent initiator function. Mol Cell Biol (1998) 1.10
Both LyF-1 and an Ets protein interact with a critical promoter element in the murine terminal transferase gene. Mol Cell Biol (1993) 1.10
A potential role for Elf-1 in terminal transferase gene regulation. Mol Cell Biol (1996) 1.10
Isolation of a murine gene encoding a nucleic acid-binding protein with homology to hnRNP K. Nucleic Acids Res (1993) 1.07
Similarity between a ubiquitous promoter element in an ancient eukaryote and mammalian initiator elements. Proc Natl Acad Sci U S A (1994) 1.05
Inhibition of simian virus 40 DNA replication by specific modification of T-antigen with oxidized ATP. J Biol Chem (1986) 1.04
Sp1 activation of a TATA-less promoter requires a species-specific interaction involving transcription factor IID. Nucleic Acids Res (1998) 1.00
Alternative pathway for induction of human immunodeficiency virus gene expression: involvement of the general transcription machinery. J Virol (1991) 1.00
Combinatorial regulation of transcription. I: General aspects of transcriptional control. Immunity (1995) 0.99
A common ATP requirement for open complex formation and transcription at promoters containing initiator or TATA elements. J Biol Chem (1993) 0.96
Initiator recognition in a primitive eukaryote: IBP39, an initiator-binding protein from Trichomonas vaginalis. Mol Cell Biol (2001) 0.90
Roles of TATA and initiator elements in determining the start site location and direction of RNA polymerase II transcription. J Biol Chem (1992) 0.87
Mechanisms of transcriptional regulation in lymphocyte progenitors: insight from an analysis of the terminal transferase promoter. Cold Spring Harb Symp Quant Biol (1999) 0.81
Inhibition of simian virus 40 DNA replication in vitro by poly(ADP-ribosyl)ated diadenosine tetraphosphate. J Biol Chem (1987) 0.80