Published in Mutat Res on February 14, 2006
Polo-box domain: a versatile mediator of polo-like kinase function. Cell Mol Life Sci (2010) 1.85
CHK2 kinase in the DNA damage response and beyond. J Mol Cell Biol (2014) 1.05
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus. Nucleic Acids Res (2010) 1.02
Plk3 interacts with and specifically phosphorylates VRK1 in Ser342, a downstream target in a pathway that induces Golgi fragmentation. Mol Cell Biol (2008) 0.99
Centrosomal Chk2 in DNA damage responses and cell cycle progression. Cell Cycle (2010) 0.95
The role of Plk3 in oncogenesis. Oncogene (2015) 0.83
Calcium- and integrin-binding protein 1 regulates endomitosis and its interaction with Polo-like kinase 3 is enhanced in endomitotic Dami cells. PLoS One (2011) 0.83
Effects of low doses of ionizing radiation exposures on stress-responsive gene expression in human embryonic stem cells. Int J Mol Sci (2014) 0.82
Gene expression patterns in heterozygous Plk4 murine embryonic fibroblasts. BMC Genomics (2009) 0.82
Bcl-xL phosphorylation at Ser49 by polo kinase 3 during cell cycle progression and checkpoints. Cell Signal (2011) 0.81
Enrichment of nuclear S100A4 during G2/M in colorectal cancer cells: possible association with cyclin B1 and centrosomes. Clin Exp Metastasis (2015) 0.79
Over expression of Plk1 does not induce cell division in rat cardiac myocytes in vitro. PLoS One (2009) 0.78
Mitotic Kinases and p53 Signaling. Biochem Res Int (2012) 0.78
Osmotic stress-induced phosphorylation of H2AX by polo-like kinase 3 affects cell cycle progression in human corneal epithelial cells. J Biol Chem (2014) 0.77
Chk2*1100delC Acts in synergy with the Ron receptor tyrosine kinase to accelerate mammary tumorigenesis in mice. Cancer Lett (2010) 0.77
Maintaining Genome Stability in Defiance of Mitotic DNA Damage. Front Genet (2016) 0.75
Checkpoint Kinase 2 Negatively Regulates Androgen Sensitivity and Prostate Cancer Cell Growth. Cancer Res (2015) 0.75
Pseudomonas aeruginosa anaerobic respiration in biofilms: relationships to cystic fibrosis pathogenesis. Dev Cell (2002) 4.94
Embryonic stem cells and somatic cells differ in mutation frequency and type. Proc Natl Acad Sci U S A (2002) 2.17
Restoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation. Proc Natl Acad Sci U S A (2004) 1.96
NudE and NudEL are required for mitotic progression and are involved in dynein recruitment to kinetochores. J Cell Biol (2007) 1.85
Anaerobic killing of mucoid Pseudomonas aeruginosa by acidified nitrite derivatives under cystic fibrosis airway conditions. J Clin Invest (2006) 1.79
Multiple modes of cytoplasmic dynein regulation. Nat Cell Biol (2012) 1.59
Mammalian Polo-like kinase 3 (Plk3) is a multifunctional protein involved in stress response pathways. Oncogene (2002) 1.40
RB signaling prevents replication-dependent DNA double-strand breaks following genotoxic insult. Nucleic Acids Res (2004) 1.33
Mechanical stochastic tug-of-war models cannot explain bidirectional lipid-droplet transport. Proc Natl Acad Sci U S A (2011) 1.26
Mouse embryonic stem cells, but not somatic cells, predominantly use homologous recombination to repair double-strand DNA breaks. Stem Cells Dev (2010) 1.23
DNA repair in murine embryonic stem cells and differentiated cells. Exp Cell Res (2008) 1.22
High-resolution imaging reveals indirect coordination of opposite motors and a role for LIS1 in high-load axonal transport. J Cell Biol (2011) 1.19
The human DEK oncogene regulates DNA damage response signaling and repair. Nucleic Acids Res (2011) 1.13
Co-mutagenic activity of arsenic and benzo[a]pyrene in mouse skin. Mutat Res (2005) 1.11
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation. Oncogene (2004) 1.09
Flt-3 ligand: a potent dendritic cell stimulator and novel antitumor agent. Cancer Biol Ther (2002) 1.08
Two-pronged survival strategy for the major cystic fibrosis pathogen, Pseudomonas aeruginosa, lacking the capacity to degrade nitric oxide during anaerobic respiration. EMBO J (2007) 1.07
Accelerating drug discovery. EMBO Rep (2004) 1.06
The Plk3-Cdc25 circuit. Oncogene (2005) 1.05
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus. Nucleic Acids Res (2010) 1.02
Functional and molecular interactions between ERK and CHK2 in diffuse large B-cell lymphoma. Nat Commun (2011) 1.02
Retracted G protein-induced trafficking of voltage-dependent calcium channels. J Biol Chem (2005) 1.00
Cytoplasmic dynein crosslinks and slides anti-parallel microtubules using its two motor domains. Elife (2013) 0.96
Mlh1 mediates tissue-specific regulation of mitotic recombination. Oncogene (2004) 0.96
The breast cancer susceptibility allele CHEK2*1100delC promotes genomic instability in a knock-in mouse model. Mutat Res (2006) 0.94
Retinoblastoma tumor suppressor: analyses of dynamic behavior in living cells reveal multiple modes of regulation. Mol Cell Biol (2003) 0.94
Point mutation in the NF2 gene of HEI-193 human schwannoma cells results in the expression of a merlin isoform with attenuated growth suppressive activity. Mutat Res (2007) 0.93
Visualization of mosaicism in tissues of normal and mismatch-repair-deficient mice carrying a microsatellite-containing transgene. Mutat Res (2002) 0.93
Expression patterns of LIS1, dynein and their interaction partners dynactin, NudE, NudEL and NudC in human gliomas suggest roles in invasion and proliferation. Acta Neuropathol (2007) 0.91
Critical regulation of genes for tumor cell migration by AP-1. Clin Exp Metastasis (2004) 0.90
Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias. Proc Natl Acad Sci U S A (2009) 0.87
Nuclear receptor LRH-1/NR5A2 is required and targetable for liver endoplasmic reticulum stress resolution. Elife (2014) 0.86
Invasion is a genetic program regulated by transcription factors. Curr Opin Genet Dev (2005) 0.85
Radiation-induced genetic instability in vivo depends on p53 status. Mutat Res (2002) 0.85
Mismatch and base excision repair proficiency in murine embryonic stem cells. DNA Repair (Amst) (2011) 0.84
The abundance of Rad51 protein in mouse embryonic stem cells is regulated at multiple levels. Stem Cell Res (2012) 0.84
X-rays induce distinct patterns of somatic mutation in fetal versus adult hematopoietic cells. DNA Repair (Amst) (2007) 0.84
Mutation frequencies and spectra in DNA polymerase eta-deficient mice. Cancer Res (2008) 0.84
FERM domain phosphoinositide binding targets merlin to the membrane and is essential for its growth-suppressive function. Mol Cell Biol (2011) 0.84
Loss of heterozygosity and point mutation at Aprt locus in T cells and fibroblasts of Pms2-/- mice. Oncogene (2002) 0.83
Absence of polo-like kinase 3 in mice stabilizes Cdc25A after DNA damage but is not sufficient to produce tumors. Mutat Res (2011) 0.82
A patient-derived somatic mutation in the epidermal growth factor receptor ligand-binding domain confers increased sensitivity to cetuximab in head and neck cancer. Eur J Cancer (2013) 0.82
Impaired expression of an organic cation transporter, IMPT1, in a knockout mouse model for kidney stone disease. Urol Res (2003) 0.82
Genomic signatures of near-extinction and rebirth of the crested ibis and other endangered bird species. Genome Biol (2014) 0.82
Mouse embryonic stem cells undergo charontosis, a novel programmed cell death pathway dependent upon cathepsins, p53, and EndoG, in response to etoposide treatment. Stem Cell Res (2013) 0.81
DNA damage response and mutagenesis in mouse embryonic stem cells. Methods Mol Biol (2006) 0.80
Antitumor effect of secreted Flt3-ligand can act at distant tumor sites in a murine model of head and neck cancer. Cancer Gene Ther (2003) 0.80
Chk2*1100delC Acts in synergy with the Ron receptor tyrosine kinase to accelerate mammary tumorigenesis in mice. Cancer Lett (2010) 0.77
Ionizing radiation is a potent inducer of mitotic recombination in mouse embryonic stem cells. Mutat Res (2011) 0.77
A human cancer-predisposing polymorphism in Cdc25A is embryonic lethal in the mouse and promotes ASK-1 mediated apoptosis. Cell Div (2011) 0.77
Correction: Nuclear receptor LRH-1/NR5A2 is required and targetable for liver endoplasmic reticulum stress resolution. Elife (2015) 0.77
A 5'-distal enhanceosome in the PDGF-A gene is activated in choriocarcinoma cells via ligand-independent binding of vitamin D receptor and constitutive jun kinase signaling. Oncogene (2005) 0.76
Exposure of mice to arsenic and/or benzo[a]pyrene does not increase the frequency of Aprt-deficient cells recovered from explanted skin of Aprt heterozygous mice. Environ Mol Mutagen (2006) 0.76
Bacterial biofilms of importance to medicine and bioterrorism: proteomic techniques to identify novel vaccine components and drug targets. Expert Opin Biol Ther (2003) 0.76
Alloantigen gene therapy for head and neck cancer: evaluation of animal models. Head Neck (2003) 0.76
Induction of alpha-catenin, integrin alpha3, integrin beta6, and PDGF-B by 2,8-dihydroxyadenine crystals in cultured kidney epithelial cells. Exp Nephrol (2002) 0.75
Gender- and age-dependent changes in kidney androgen protein mRNA expression in a knockout mouse model for nephrolithiasis. J Histochem Cytochem (2002) 0.75
Major histocompatibility gene therapy: the importance of haplotype and beta 2-microglobulin. Laryngoscope (2004) 0.75