PubRank

Shigeru Kawakami

Author PubWeight™ 71.64‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 piggyBac transposon-mediated long-term gene expression in mice. Mol Ther 2010 1.33
2 Novel PEG-matrix metalloproteinase-2 cleavable peptide-lipid containing galactosylated liposomes for hepatocellular carcinoma-selective targeting. J Control Release 2006 1.15
3 Strategies for in vivo delivery of siRNAs: recent progress. BioDrugs 2010 1.14
4 Small interfering RNA delivery to the liver by intravenous administration of galactosylated cationic liposomes in mice. Biomaterials 2006 1.07
5 Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethyleneimine on hepatoma cells and mouse liver. Mol Ther 2003 1.01
6 PEGylated lysine dendrimers for tumor-selective targeting after intravenous injection in tumor-bearing mice. J Control Release 2006 0.99
7 Renal press-mediated transfection method for plasmid DNA and siRNA to the kidney. Biochem Biophys Res Commun 2008 0.96
8 Efficient targeting to alveolar macrophages by intratracheal administration of mannosylated liposomes in rats. J Control Release 2007 0.95
9 Effect of mannose density on mannose receptor-mediated cellular uptake of mannosylated O/W emulsions by macrophages. J Control Release 2006 0.93
10 Lipid carrier systems for targeted drug and gene delivery. Chem Pharm Bull (Tokyo) 2005 0.92
11 Efficient gene transfection by histidine-modified chitosan through enhancement of endosomal escape. Bioconjug Chem 2010 0.91
12 Gamma-polyglutamic acid-coated vectors for effective and safe gene therapy. J Control Release 2009 0.91
13 Novel histidine-conjugated galactosylated cationic liposomes for efficient hepatocyte-selective gene transfer in human hepatoma HepG2 cells. J Control Release 2006 0.90
14 Enhanced anti-inflammation of inhaled dexamethasone palmitate using mannosylated liposomes in an endotoxin-induced lung inflammation model. Mol Pharmacol 2008 0.88
15 Enhanced transfection efficiency into macrophages and dendritic cells by a combination method using mannosylated lipoplexes and bubble liposomes with ultrasound exposure. Hum Gene Ther 2010 0.88
16 Effect of galactose density on asialoglycoprotein receptor-mediated uptake of galactosylated liposomes. J Pharm Sci 2005 0.88
17 Biodistribution characteristics of amino acid dendrimers and their PEGylated derivatives after intravenous administration. J Control Release 2006 0.88
18 Development of an ultrasound-responsive and mannose-modified gene carrier for DNA vaccine therapy. Biomaterials 2010 0.87
19 Encapsulation of the synthetic retinoids Am80 and LE540 into polymeric micelles and the retinoids' release control. J Control Release 2009 0.87
20 Targeting efficiency of galactosylated liposomes to hepatocytes in vivo: effect of lipid composition. Pharm Res 2002 0.86
21 Efficient gene transfer into macrophages and dendritic cells by in vivo gene delivery with mannosylated lipoplex via the intraperitoneal route. J Pharmacol Exp Ther 2006 0.86
22 Uptake characteristics of galactosylated emulsion by HepG2 hepatoma cells. Int J Pharm 2005 0.86
23 Intranasal administration of CpG DNA lipoplex prevents pulmonary metastasis in mice. Cancer Lett 2009 0.85
24 Development of an antigen-presenting cell-targeted DNA vaccine against melanoma by mannosylated liposomes. Biomaterials 2007 0.85
25 Enhanced in vivo antitumor efficacy of fenretinide encapsulated in polymeric micelles. Int J Pharm 2009 0.84
26 Mannosylated semiconductor quantum dots for the labeling of macrophages. J Control Release 2007 0.84
27 Designing dendrimers for drug delivery and imaging: pharmacokinetic considerations. Pharm Res 2010 0.84
28 In vitro evaluation of inhibitory effect of nuclear factor-kappaB activity by small interfering RNA on pro-tumor characteristics of M2-like macrophages. Biol Pharm Bull 2013 0.84
29 Intratracheally instilled mannosylated cationic liposome/NFκB decoy complexes for effective prevention of LPS-induced lung inflammation. J Control Release 2009 0.83
30 The development of a gene vector electrostatically assembled with a polysaccharide capsule. Biomaterials 2009 0.83
31 Development of lysine-histidine dendron modified chitosan for improving transfection efficiency in HEK293 cells. J Control Release 2011 0.83
32 Targeted and sustained drug delivery using PEGylated galactosylated liposomes. Int J Pharm 2003 0.83
33 Enhanced hepatocyte-selective in vivo gene expression by stabilized galactosylated liposome/plasmid DNA complex using sodium chloride for complex formation. Mol Ther 2004 0.83
34 Inhibition of cancer cell growth by GRP78 siRNA lipoplex via activation of unfolded protein response. Biol Pharm Bull 2014 0.82
35 Suppression of melanoma growth and metastasis by DNA vaccination using an ultrasound-responsive and mannose-modified gene carrier. Mol Pharm 2011 0.82
36 Analysis of hepatic disposition of galactosylated cationic liposome/plasmid DNA complexes in perfused rat liver. Pharm Res 2003 0.82
37 Basic fibroblast growth factor-binding peptide as a novel targeting ligand of drug carrier to tumor cells. J Drug Target 2006 0.82
38 Use of mannosylated cationic liposomes/ immunostimulatory CpG DNA complex for effective inhibition of peritoneal dissemination in mice. J Gene Med 2008 0.82
39 Polyamidoamine dendrimer-conjugated quantum dots for efficient labeling of primary cultured mesenchymal stem cells. Biomaterials 2011 0.82
40 Biodistribution characteristics of mannosylated and fucosylated O/W emulsions in mice. J Drug Target 2005 0.82
41 Efficient suppression of murine intracellular adhesion molecule-1 using ultrasound-responsive and mannose-modified lipoplexes inhibits acute hepatic inflammation. Hepatology 2012 0.82
42 Interaction with blood components plays a crucial role in asialoglycoprotein receptor-mediated in vivo gene transfer by galactosylated lipoplex. J Pharmacol Exp Ther 2005 0.81
43 Evaluation of osteoclastogenesis via NFκB decoy/mannosylated cationic liposome-mediated inhibition of pro-inflammatory cytokine production from primary cultured macrophages. Pharm Res 2011 0.81
44 Optimization of tumor-selective targeting by basic fibroblast growth factor-binding peptide grafted PEGylated liposomes. J Control Release 2007 0.81
45 Pressure-mediated transfection of murine spleen and liver. Hum Gene Ther 2009 0.81
46 Enhanced DNA vaccine potency by mannosylated lipoplex after intraperitoneal administration. J Gene Med 2006 0.81
47 Enhancement of immune responses by DNA vaccination through targeted gene delivery using mannosylated cationic liposome formulations following intravenous administration in mice. Biochem Biophys Res Commun 2004 0.81
48 Immunostimulatory characteristics induced by linear polyethyleneimine-plasmid DNA complexes in cultured macrophages. Hum Gene Ther 2009 0.81
49 The potential role of fucosylated cationic liposome/NFkappaB decoy complexes in the treatment of cytokine-related liver disease. Biomaterials 2006 0.80
50 Inhibition of liver metastasis by targeting of immunomodulators using mannosylated liposome carriers. J Control Release 2002 0.80
51 Uptake characteristics of mannosylated and fucosylated bovine serum albumin in primary cultured rat sinusoidal endothelial cells and Kupffer cells. Int J Pharm 2004 0.80
52 Self-assemble gene delivery system for molecular targeting using nucleic acid aptamer. Gene 2011 0.80
53 Ocular pharmacokinetic/ pharmacodynamic modeling for bunazosin after instillation into rabbits. Pharm Res 2004 0.79
54 Tissue and intrahepatic distribution and subcellular localization of a mannosylated lipoplex after intravenous administration in mice. J Control Release 2004 0.79
55 In vivo site-specific transfection of naked plasmid DNA and siRNAs in mice by using a tissue suction device. PLoS One 2012 0.79
56 Inhibition of liver metastasis by all-trans retinoic acid incorporated into O/W emulsions in mice. Int J Pharm 2006 0.79
57 Anionic amino acid dendrimer-trastuzumab conjugates for specific internalization in HER2-positive cancer cells. Mol Pharm 2010 0.79
58 Inhibition of pulmonary metastasis in mice by all-trans retinoic acid incorporated in cationic liposomes. J Control Release 2006 0.78
59 Implantable pneumatically actuated microsystem for renal pressure-mediated transfection in mice. J Control Release 2011 0.78
60 Anti-tumor effect of all-trans retinoic acid loaded polymeric micelles in solid tumor bearing mice. Pharm Res 2007 0.78
61 Quantitation of sulfur-containing amino acids, homocysteine, methionine and cysteine in dried blood spot from newborn baby by HPLC-fluorescence detection. Biomed Chromatogr 2014 0.78
62 Comparison of piggyBac transposition efficiency between linear and circular donor vectors in mammalian cells. J Biotechnol 2011 0.78
63 Simultaneous determination of propofol and remifentanil in rat plasma by liquid chromatography-tandem mass spectrometry: application to preclinical pharmacokinetic drug-drug interaction analysis. Biomed Chromatogr 2014 0.78
64 Effect of the particle size of galactosylated lipoplex on hepatocyte-selective gene transfection after intraportal administration. Biol Pharm Bull 2006 0.78
65 Prednisolone retention in integrated liposomes by chemical approach and pharmaceutical approach. J Control Release 2004 0.78
66 Tumour-associated macrophages targeted transfection with NF-κB decoy/mannose-modified bubble lipoplexes inhibits tumour growth in tumour-bearing mice. J Drug Target 2014 0.78
67 Combination of nanoparticles with physical stimuli toward cancer therapy. Biol Pharm Bull 2014 0.78
68 PEGylated liposomes loading palmitoyl prednisolone for prolonged blood concentration of prednisolone. Biol Pharm Bull 2006 0.78
69 Block copolymer design for stable encapsulation of N-(4-hydroxyphenyl)retinamide into polymeric micelles in mice. Int J Pharm 2008 0.78
70 The elucidation of gene transferring mechanism by ultrasound-responsive unmodified and mannose-modified lipoplexes. Biomaterials 2011 0.78
71 Biodistribution characteristics of galactosylated emulsions and incorporated probucol for hepatocyte-selective targeting of lipophilic drugs in mice. Pharm Res 2004 0.78
72 Glycosylated carriers for cell-selective and nuclear delivery of nucleic acids. Front Biosci (Landmark Ed) 2011 0.77
73 One-side-coated insert as a unique ophthalmic drug delivery system. J Control Release 2003 0.77
74 Involvement of activated transcriptional process in efficient gene transfection using unmodified and mannose-modified bubble lipoplexes with ultrasound exposure. J Control Release 2011 0.77
75 The involvement of NK cell activation following intranasal administration of CpG DNA lipoplex in the prevention of pulmonary metastasis and peritoneal dissemination in mice. Clin Exp Metastasis 2011 0.77
76 Key physiological phenomena governing transgene expression based on tissue pressure-mediated transfection in mice. Biol Pharm Bull 2010 0.77
77 Antitumor effect of nuclear factor-κB decoy transfer by mannose-modified bubble lipoplex into macrophages in mouse malignant ascites. Cancer Sci 2014 0.77
78 The role of dioleoylphosphatidylethanolamine (DOPE) in targeted gene delivery with mannosylated cationic liposomes via intravenous route. J Control Release 2005 0.77
79 Anti-MUC1 Aptamer/Negatively Charged Amino Acid Dendrimer Conjugates for Targeted Delivery to Human Lung Adenocarcinoma A549 Cells. Biol Pharm Bull 2016 0.76
80 Glycosylated cationic liposomes for carbohydrate receptor-mediated gene transfer. Methods Enzymol 2003 0.76
81 Efficient protection by cationized catalase against H2O2 injury in primary cultured alveolar epithelial cells. J Control Release 2007 0.76
82 Evaluation of proinflammatory cytokine production and liver injury induced by plasmid DNA/cationic liposome complexes with various mixing ratios in mice. Eur J Pharm Biopharm 2008 0.76
83 Validation of an LC-MS/MS Method for the Determination of Propofol, Midazolam, and Carbamazepine in Rat Plasma: Application to Monitor Their Concentrations Following Co-administration. Biol Pharm Bull 2015 0.76
84 Efficient peritoneal dissemination treatment obtained by an immunostimulatory phosphorothioate-type CpG DNA/cationic liposome complex in mice. J Control Release 2008 0.76
85 Factors influencing the surface modification of mesenchymal stem cells with fluorescein-pegylated lipids. Biol Pharm Bull 2013 0.76
86 Intracellular trafficking is the important process that determines the optimal charge ratio on transfection by galactosylated lipoplex in HEPG2 cells. Biol Pharm Bull 2006 0.76
87 Enhanced gene transfection in macrophages by histidine-conjugated mannosylated cationic liposomes. Biol Pharm Bull 2009 0.75
88 Incorporation of all-trans retinoic acid into lipoplexes inhibits nuclear factor kappaB activation mediated liver injury induced by lipoplexes in mice. J Gene Med 2008 0.75
89 Effect of low-molecular-weight beta-cyclodextrin polymer on release of drugs from mucoadhesive buccal film dosage forms. Biol Pharm Bull 2005 0.75
90 Intravenous administration of mannosylated cationic liposome/NFkappaB decoy complexes effectively prevent LPS-induced cytokine production in a murine liver failure model. FEBS Lett 2006 0.75
91 Liver suction-mediated transfection in mice using a pressure-controlled computer system. Biol Pharm Bull 2014 0.75
92 [Development and therapeutic application of transposon-based vectors]. Yakugaku Zasshi 2009 0.75
93 Long-term in vivo gene expression in mouse kidney using φC31 integrase and electroporation. J Drug Target 2015 0.75
94 Mannosylated cationic liposomes/CpG DNA complex for the treatment of hepatic metastasis after intravenous administration in mice. J Pharm Sci 2009 0.75
95 Absorption characteristics of model compounds with different molecular weights from the serosal caecal surface in rats. J Pharm Pharmacol 2002 0.75
96 Evaluation of long-term gene expression in mouse liver using PhiC31 integrase and hydrodynamic injection. Biol Pharm Bull 2012 0.75
97 [Development of nucleic acid transfection technology to the kidney]. Yakugaku Zasshi 2008 0.75
98 Analysis of hepatic disposition of native and galactosylated polyethylenimine complexed with plasmid DNA in perfused rat liver. Drug Metab Pharmacokinet 2003 0.75
99 NFkappaB decoy delivery using dendritic poly(l-lysine) for treatment of endotoxin-induced hepatitis in mice. Bioorg Med Chem 2009 0.75
100 Suppressive effects of sugar-modified cationic liposome/NF-kappaB decoy complexes on adenovirus vector-induced innate immune responses. J Control Release 2008 0.75
101 Intracellular distribution of NFkappaB decoy and its inhibitory effect on TNFalpha production by LPS stimulated RAW 264.7 cells. J Control Release 2005 0.75
102 Luminol Chemiluminescence Profile of O/W Emulsions during Thermal Oxidation. Anal Sci 2017 0.75
103 Development of the liver- and lobe-selective nonviral gene transfer following the instillation of naked plasmid DNA using catheter on the liver surface in mice. Pharm Res 2003 0.75
104 Evaluation of inflammatory responses due to small interfering RNA transfer using unmodified- and mannose-modified bubble lipoplexes with ultrasound exposure in primary cultured macrophages. J Drug Target 2014 0.75
105 Bovine serum albumin as a lyoprotectant for preparation of DNA dry powder formulations using the spray-freeze drying method. Biol Pharm Bull 2012 0.75
106 [Development of cell-selective targeting systems of NFkappaB decoy for inflammation therapy]. Yakugaku Zasshi 2008 0.75