Toby Lawrence

Author PubWeight™ 52.17‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell 2006 5.97
2 Inflammatory resolution: new opportunities for drug discovery. Nat Rev Drug Discov 2004 5.08
3 "Re-educating" tumor-associated macrophages by targeting NF-kappaB. J Exp Med 2008 4.38
4 Granulocyte-macrophage colony-stimulating factor (CSF) and macrophage CSF-dependent macrophage phenotypes display differences in cytokine profiles and transcription factor activities: implications for CSF blockade in inflammation. J Immunol 2007 2.98
5 Sustained desensitization to bacterial Toll-like receptor ligands after resolution of respiratory influenza infection. J Exp Med 2008 2.77
6 Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1. J Exp Med 2006 2.46
7 The tumor-promoting actions of TNF-alpha involve TNFR1 and IL-17 in ovarian cancer in mice and humans. J Clin Invest 2009 2.42
8 The kinase p38 alpha serves cell type-specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expression. Nat Immunol 2008 2.34
9 I{kappa}B kinase (IKK){beta}, but not IKK{alpha}, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss. J Exp Med 2005 2.21
10 Hematopoietic prostaglandin D2 synthase controls the onset and resolution of acute inflammation through PGD2 and 15-deoxyDelta12 14 PGJ2. Proc Natl Acad Sci U S A 2007 2.10
11 Sword and shield: linked group B streptococcal beta-hemolysin/cytolysin and carotenoid pigment function to subvert host phagocyte defense. Proc Natl Acad Sci U S A 2004 1.95
12 Allergen-induced peribronchial fibrosis and mucus production mediated by IkappaB kinase beta-dependent genes in airway epithelium. Proc Natl Acad Sci U S A 2005 1.87
13 Reduced infiltration and increased apoptosis of leukocytes at sites of inflammation by systemic administration of a membrane-permeable IkappaBalpha repressor. Arthritis Rheum 2004 1.79
14 An antiinflammatory role for IKKbeta through the inhibition of "classical" macrophage activation. J Exp Med 2008 1.77
15 Regulation of macrophage function in tumors: the multifaceted role of NF-kappaB. Blood 2009 1.59
16 Inducible cyclooxygenase-derived 15-deoxy(Delta)12-14PGJ2 brings about acute inflammatory resolution in rat pleurisy by inducing neutrophil and macrophage apoptosis. FASEB J 2003 1.53
17 Inflammation and cancer: a double-edged sword. Cancer Cell 2007 1.52
18 Nuclear factor-kappaB and tumor-associated macrophages. Clin Cancer Res 2010 1.27
19 Novel biphasic role for lymphocytes revealed during resolving inflammation. Blood 2008 1.14
20 The pore-forming toxin β hemolysin/cytolysin triggers p38 MAPK-dependent IL-10 production in macrophages and inhibits innate immunity. PLoS Pathog 2012 1.05
21 Inhibition of NF-kappa B activity by a membrane-transducing mutant of I kappa B alpha. J Immunol 2002 1.02
22 The resolution of inflammation and cancer. Cytokine Growth Factor Rev 2009 0.98
23 Air-pouch models of inflammation and modifications for the study of granuloma-mediated cartilage degradation. Methods Mol Biol 2003 0.94
24 Cigarette smoke induced airway inflammation is independent of NF-κB signalling. PLoS One 2013 0.93
25 I kappa B kinase alpha (IKKα) activity is required for functional maturation of dendritic cells and acquired immunity to infection. EMBO J 2013 0.81
26 Investigating macrophage and malignant cell interactions in vitro. Methods Mol Biol 2009 0.78