Published in Chembiochem on April 01, 2006
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RNA SHAPE analysis in living cells. Nat Chem Biol (2012) 2.02
Probing the active site tightness of DNA polymerase in subangstrom increments. Proc Natl Acad Sci U S A (2005) 1.89
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Minor Groove Interactions between Polymerase and DNA: More Essential to Replication than Watson-Crick Hydrogen Bonds? J Am Chem Soc (1999) 1.68
Naphthalene, Phenanthrene, and Pyrene as DNA Base Analogues: Synthesis, Structure, and Fluorescence in DNA. J Am Chem Soc (1996) 1.58
Varied Molecular Interactions at the Active Sites of Several DNA Polymerases: Nonpolar Nucleoside Isosteres as Probes. J Am Chem Soc (2000) 1.43
General method for modification of liposomes for encoded assembly on supported bilayers. J Am Chem Soc (2005) 1.42
Varying DNA base-pair size in subangstrom increments: evidence for a loose, not large, active site in low-fidelity Dpo4 polymerase. Biochemistry (2006) 1.38
Fluorescent DNA base replacements: Reporters and sensors for biological systems. Org Biomol Chem (2006) 1.38
Synthesis and properties of size-expanded DNAs: toward designed, functional genetic systems. Acc Chem Res (2007) 1.36
Toward a new genetic system with expanded dimensions: size-expanded analogues of deoxyadenosine and thymidine. J Am Chem Soc (2004) 1.35
High-fidelity in vivo replication of DNA base shape mimics without Watson-Crick hydrogen bonds. Proc Natl Acad Sci U S A (2003) 1.32
Detecting RNA and DNA with templated chemical reactions. Chem Rev (2006) 1.31
Functional evidence for a small and rigid active site in a high fidelity DNA polymerase: probing T7 DNA polymerase with variably sized base pairs. J Biol Chem (2005) 1.29
Modified DNA analogues that sense light exposure with color changes. J Am Chem Soc (2004) 1.28
Requirement of Watson-Crick hydrogen bonding for DNA synthesis by yeast DNA polymerase eta. Mol Cell Biol (2003) 1.27
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Selective and Stable DNA Base Pairing without Hydrogen Bonds. J Am Chem Soc (1998) 1.24
A four-base paired genetic helix with expanded size. Science (2003) 1.23
DNA polymerase catalysis in the absence of Watson-Crick hydrogen bonds: analysis by single-turnover kinetics. Biochemistry (2006) 1.23
Structure and thermodynamics of N6-methyladenosine in RNA: a spring-loaded base modification. J Am Chem Soc (2015) 1.21
Libraries of composite polyfluors built from fluorescent deoxyribosides. J Am Chem Soc (2002) 1.21
Evidence for a Watson-Crick hydrogen bonding requirement in DNA synthesis by human DNA polymerase kappa. Mol Cell Biol (2005) 1.19
Polyfluorophores on a DNA backbone: a multicolor set of labels excited at one wavelength. J Am Chem Soc (2009) 1.19
Quencher as leaving group: efficient detection of DNA-joining reactions. J Am Chem Soc (2002) 1.19
Quenched auto-ligating DNAs: multicolor identification of nucleic acids at single nucleotide resolution. J Am Chem Soc (2004) 1.19
Importance of hydrogen bonding for efficiency and specificity of the human mitochondrial DNA polymerase. J Biol Chem (2007) 1.19
Model systems for understanding DNA base pairing. Curr Opin Chem Biol (2007) 1.18
Flow cytometric detection of specific RNAs in native human cells with quenched autoligating FRET probes. Proc Natl Acad Sci U S A (2005) 1.16
Remarkable sensitivity to DNA base shape in the DNA polymerase active site. Angew Chem Int Ed Engl (2006) 1.15
Highly Precise Shape Mimicry by a Difluorotoluene Deoxynucleoside, a Replication-Competent Substitute for Thymidine. Angew Chem Int Ed Engl (1997) 1.14
Chemoselective covalent coupling of oligonucleotide probes to self-assembled monolayers. J Am Chem Soc (2005) 1.13
DNA-multichromophore systems. Chem Rev (2012) 1.10
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Imaging of RNA in bacteria with self-ligating quenched probes. J Am Chem Soc (2002) 1.10
Dynamics of nucleotide incorporation: snapshots revealed by 2-aminopurine fluorescence studies. Biochemistry (2006) 1.10
Water-soluble organocatalysts for hydrazone and oxime formation. J Org Chem (2013) 1.08
Efficient nucleic acid detection by templated reductive quencher release. J Am Chem Soc (2009) 1.07
Structure and Base Pairing Properties of a Replicable Nonpolar Isostere for Deoxyadenosine. J Org Chem (1998) 1.07
RNA major groove modifications improve siRNA stability and biological activity. Nucleic Acids Res (2008) 1.07
A series of nonpolar thymidine analogues of increasing size: DNA base pairing and stacking properties. J Org Chem (2005) 1.06
Destabilizing universal linkers for signal amplification in self-ligating probes for RNA. J Am Chem Soc (2004) 1.05
Redesigning the architecture of the base pair: toward biochemical and biological function of new genetic sets. Chem Biol (2009) 1.05
Exploring the limits of DNA size: naphtho-homologated DNA bases and pairs. J Am Chem Soc (2006) 1.04
Quenched probes for highly specific detection of cellular RNAs. Trends Biotechnol (2005) 1.04
Probing the requirements for recognition and catalysis in Fpg and MutY with nonpolar adenine isosteres. J Am Chem Soc (2003) 1.04
Importance of ortho proton donors in catalysis of hydrazone formation. Org Lett (2013) 1.03
C-Nucleosides Derived from Simple Aromatic Hydrocarbons. Synlett (1997) 1.01
Helix-forming properties of size-expanded DNA, an alternative four-base genetic form. J Am Chem Soc (2005) 1.01
A highly effective nonpolar isostere of deoxyguanosine: synthesis, structure, stacking, and base pairing. J Org Chem (2002) 1.00
The roles of hydrogen bonding and sterics in RNA interference. Angew Chem Int Ed Engl (2006) 1.00
Nonpolar nucleoside mimics as active substrates for human thymidine kinases. J Am Chem Soc (2009) 1.00
Expanded-size bases in naturally sized DNA: evaluation of steric effects in Watson-Crick pairing. J Am Chem Soc (2004) 1.00
Quenching of fluorescent nucleobases by neighboring DNA: the "insulator" concept. Chembiochem (2008) 0.99
Identification of a selective polymerase enables detection of N(6)-methyladenosine in RNA. J Am Chem Soc (2013) 0.99
Oligodeoxyfluorosides: Strong Sequence Dependence of Fluorescence Emission. Tetrahedron (2007) 0.99
Assembly of the complete eight-base artificial genetic helix, xDNA, and its interaction with the natural genetic system. Angew Chem Int Ed Engl (2005) 0.99
Unnatural substrates reveal the importance of 8-oxoguanine for in vivo mismatch repair by MutY. Nat Chem Biol (2007) 0.98
Fluorinated DNA bases as probes of electrostatic effects in DNA base stacking. Angew Chem Int Ed Engl (2003) 0.98
Oligomeric fluorescent labels for DNA. Bioconjug Chem (2005) 0.97
Structural Optimization of Non-Nucleotide Loop Replacements for Duplex and Triplex DNAs. J Am Chem Soc (1995) 0.96
Fluorescence of size-expanded DNA bases: reporting on DNA sequence and structure with an unnatural genetic set. J Am Chem Soc (2008) 0.96
Evolving a polymerase for hydrophobic base analogues. J Am Chem Soc (2009) 0.95
Size-expanded analogues of dG and dC: synthesis and pairing properties in DNA. J Org Chem (2005) 0.95
Fluorescence quenchers for hydrazone and oxime orthogonal bioconjugation. Bioconjug Chem (2012) 0.94
Efficient quenching of oligomeric fluorophores on a DNA backbone. J Am Chem Soc (2007) 0.94
Solution Structure of a Nonpolar, Non-Hydrogen-Bonded Base Pair Surrogate in DNA. J Am Chem Soc (2000) 0.94
Hydrolysis of RNA/DNA hybrids containing nonpolar pyrimidine isosteres defines regions essential for HIV type 1 polypurine tract selection. Proc Natl Acad Sci U S A (2003) 0.94
Versatile 5'-functionalization of oligonucleotides on solid support: amines, azides, thiols, and thioethers via phosphorus chemistry. J Org Chem (2004) 0.94
A new four-base genetic helix, yDNA, composed of widened benzopyrimidine-purine pairs. J Am Chem Soc (2005) 0.94
A set of nonpolar thymidine nucleoside analogues with gradually increasing size. Org Lett (2004) 0.94
Enhanced base pairing and replication efficiency of thiothymidines, expanded-size variants of thymidine. J Am Chem Soc (2006) 0.94
Probing the interaction of archaeal DNA polymerases with deaminated bases using X-ray crystallography and non-hydrogen bonding isosteric base analogues. Biochemistry (2010) 0.93
Polyfluorophores on a DNA backbone: sensors of small molecules in the vapor phase. Angew Chem Int Ed Engl (2010) 0.93
Sensing metal ions with DNA building blocks: fluorescent pyridobenzimidazole nucleosides. J Am Chem Soc (2006) 0.93
Site-directed mutagenesis in the fingers subdomain of HIV-1 reverse transcriptase reveals a specific role for the beta3-beta4 hairpin loop in dNTP selection. J Mol Biol (2006) 0.92
Dissecting chemical interactions governing RNA polymerase II transcriptional fidelity. J Am Chem Soc (2012) 0.92
Selective pairing of polyfluorinated DNA bases. J Am Chem Soc (2004) 0.92
Encoding phenotype in bacteria with an alternative genetic set. J Am Chem Soc (2011) 0.92
Multispectral labeling of antibodies with polyfluorophores on a DNA backbone and application in cellular imaging. Proc Natl Acad Sci U S A (2011) 0.92
Novel Nucleoside Analogues with Fluorophores Replacing the DNA Base. Helv Chim Acta (1999) 0.91
DNA-polyfluorophore excimers as sensitive reporters for esterases and lipases. Chem Commun (Camb) (2010) 0.91
Differentiating a diverse range of volatile organic compounds with polyfluorophore sensors built on a DNA scaffold. Chemistry (2010) 0.91
RNA-templated chemistry in cells: discrimination of Escherichia, Shigella and Salmonella bacterial strains with a new two-color FRET strategy. Chembiochem (2006) 0.91
Artificial human telomeres from DNA nanocircle templates. Proc Natl Acad Sci U S A (2002) 0.91
Toward a designed, functioning genetic system with expanded-size base pairs: solution structure of the eight-base xDNA double helix. J Am Chem Soc (2006) 0.91
Differentiating between fluorescence-quenching metal ions with polyfluorophore sensors built on a DNA backbone. J Am Chem Soc (2011) 0.90
Steric effects in RNA interference: probing the influence of nucleobase size and shape. Chemistry (2008) 0.90
7-Azidomethoxy-coumarins as profluorophores for templated nucleic acid detection. Chembiochem (2008) 0.90
A Novel 5'-Iodonucleoside Allows Efficient Nonenzymatic Ligation of Single-stranded and Duplex DNAs. Tetrahedron Lett (1997) 0.89
Quenched autoligation probes allow discrimination of live bacterial species by single nucleotide differences in rRNA. Nucleic Acids Res (2005) 0.89
Efficient bacterial transcription of DNA nanocircle vectors with optimized single-stranded promoters. Proc Natl Acad Sci U S A (2001) 0.89
Direct comparison of A- and T-strand minor groove interactions in DNA curvature at A tracts. Biochemistry (2004) 0.89
Base pair hydrogen bonds are essential for proofreading selectivity by the human mitochondrial DNA polymerase. J Biol Chem (2007) 0.89