Published in Diabetes on March 01, 2006
Expression of Protein Kinase C Isoforms in Pancreatic Islets and Liver of Male Goto-Kakizaki Rats, a Model of Type 2 Diabetes. PLoS One (2015) 1.39
Protein kinase C function in muscle, liver, and beta-cells and its therapeutic implications for type 2 diabetes. Diabetes (2008) 1.33
Rationally designed peptide regulators of protein kinase C. Trends Endocrinol Metab (2008) 1.17
Constitutive endocytic recycling and protein kinase C-mediated lysosomal degradation control K(ATP) channel surface density. J Biol Chem (2009) 1.04
Ca2+-secretion coupling is impaired in diabetic Goto Kakizaki rats. J Gen Physiol (2007) 1.01
Increased ectodomain shedding of cell adhesion molecule 1 from pancreatic islets in type 2 diabetic pancreata: correlation with hemoglobin A1c levels. PLoS One (2014) 0.80
Identification of a small molecule activator of novel PKCs for promoting glucose-dependent insulin secretion. Cell Res (2010) 0.79
PKCθ activation in pancreatic acinar cells by gastrointestinal hormones/neurotransmitters and growth factors is needed for stimulation of numerous important cellular signaling cascades. Biochim Biophys Acta (2011) 0.78
Immunogold electron microscopic demonstration of distinct submembranous localization of the activated gammaPKC depending on the stimulation. J Histochem Cytochem (2007) 0.77
Autocrine Signaling Underlies Fast Repetitive Plasma Membrane Translocation of Conventional and Novel Protein Kinase C Isoforms in β Cells. J Biol Chem (2016) 0.76
Air pollution and lung cancer incidence in 17 European cohorts: prospective analyses from the European Study of Cohorts for Air Pollution Effects (ESCAPE). Lancet Oncol (2013) 6.12
Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes. Diabetes (2002) 3.21
mTOR inhibition by rapamycin prevents beta-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes. Diabetes (2008) 2.64
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes (2011) 2.21
[Reply on new drugs against type 2 diabetes: important to gain experience and knowledge]. Lakartidningen (2008) 2.03
Cancer incidence in patients with type 1 diabetes mellitus: a population-based cohort study in Sweden. J Natl Cancer Inst (2003) 1.79
Inhibition of dipeptidyl peptidase IV improves metabolic control over a 4-week study period in type 2 diabetes. Diabetes Care (2002) 1.73
Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes. J Biol Chem (2005) 1.65
Aircraft noise and incidence of hypertension--gender specific effects. Environ Res (2010) 1.61
Work stress and low sense of coherence is associated with type 2 diabetes in middle-aged Swedish women. Diabetes Care (2003) 1.44
Single nucleotide polymorphisms in the proximal promoter region of the adiponectin (APM1) gene are associated with type 2 diabetes in Swedish caucasians. Diabetes (2004) 1.41
Mechanisms of antidiabetogenic and body weight-lowering effects of estrogen in high-fat diet-fed mice. Am J Physiol Endocrinol Metab (2008) 1.40
Aircraft noise and incidence of hypertension. Epidemiology (2007) 1.39
Long-term administration of estradiol decreases expression of hepatic lipogenic genes and improves insulin sensitivity in ob/ob mice: a possible mechanism is through direct regulation of signal transducer and activator of transcription 3. Mol Endocrinol (2006) 1.36
Modeling phasic insulin release: immediate and time-dependent effects of glucose. Diabetes (2002) 1.34
Glucotoxicity and beta-cell failure in type 2 diabetes mellitus. J Pediatr Endocrinol Metab (2003) 1.26
Performance of glucose dehydrogenase-and glucose oxidase-based blood glucose meters at high altitude and low temperature. Diabetes Care (2005) 1.22
Stimulation of autophagy improves endoplasmic reticulum stress-induced diabetes. Diabetes (2012) 1.21
Glucose amplifies fatty acid-induced endoplasmic reticulum stress in pancreatic beta-cells via activation of mTORC1. PLoS One (2009) 1.20
PPAR-alpha activation protects the type 2 diabetic myocardium against ischemia-reperfusion injury: involvement of the PI3-Kinase/Akt and NO pathway. Am J Physiol Heart Circ Physiol (2009) 1.19
Long-term exposure to ambient air pollution and incidence of cerebrovascular events: results from 11 European cohorts within the ESCAPE project. Environ Health Perspect (2014) 1.16
Patient-provider interaction from the perspectives of type 2 diabetes patients in Muscat, Oman: a qualitative study. BMC Health Serv Res (2007) 1.16
Beta-cell protein kinases and the dynamics of the insulin response to glucose. Diabetes (2002) 1.16
Nucleobindin-2/nesfatin in the endocrine pancreas: distribution and relationship to glycaemic state. J Endocrinol (2009) 1.16
Intra-islet somatostatin regulates glucagon release via type 2 somatostatin receptors in rats. Diabetes (2003) 1.15
A single nucleotide polymorphism alters the sequence of SP1 binding site in the adiponectin promoter region and is associated with diabetic nephropathy among type 1 diabetic patients in the Genetics of Kidneys in Diabetes Study. J Diabetes Complications (2008) 1.10
Abnormal expression of pancreatic islet exocytotic soluble N-ethylmaleimide-sensitive factor attachment protein receptors in Goto-Kakizaki rats is partially restored by phlorizin treatment and accentuated by high glucose treatment. Endocrinology (2002) 1.07
Explanations of socioeconomic differences in excess risk of type 2 diabetes in Swedish men and women. Diabetes Care (2004) 1.07
Down-regulated expression of exocytotic proteins in pancreatic islets of diabetic GK rats. Biochem Biophys Res Commun (2002) 1.06
Arginase inhibition restores in vivo coronary microvascular function in type 2 diabetic rats. Am J Physiol Heart Circ Physiol (2011) 1.06
Exercise training decreases the concentration of malonyl-CoA and increases the expression and activity of malonyl-CoA decarboxylase in human muscle. Am J Physiol Endocrinol Metab (2006) 1.05
The L-type voltage-gated Ca2+ channel is the Ca2+ sensor protein of stimulus-secretion coupling in pancreatic beta cells. Biochemistry (2007) 1.03
Fertility in women with type 1 diabetes: a population-based cohort study in Sweden. Diabetes Care (2007) 1.01
Ca2+-secretion coupling is impaired in diabetic Goto Kakizaki rats. J Gen Physiol (2007) 1.01
Quantitative trait loci near the insulin-degrading enzyme (IDE) gene contribute to variation in plasma insulin levels. Diabetes (2004) 1.01
Apolipoprotein M promoter polymorphisms alter promoter activity and confer the susceptibility to the development of type 1 diabetes. Clin Biochem (2008) 1.01
The type 2 diabetes-associated gene ide is required for insulin secretion and suppression of α-synuclein levels in β-cells. Diabetes (2013) 1.00
Insulin secretion: movement at all levels. Diabetes (2002) 0.99
Regulation of pdx-1 gene expression. Diabetes (2002) 0.99
AMPK regulates ER morphology and function in stressed pancreatic β-cells via phosphorylation of DRP1. Mol Endocrinol (2013) 0.98
Arterial blood pressure and long-term exposure to traffic-related air pollution: an analysis in the European Study of Cohorts for Air Pollution Effects (ESCAPE). Environ Health Perspect (2014) 0.98
Insulin resistance in type 2 diabetes: association with truncal obesity, impaired fitness, and atypical malonyl coenzyme A regulation. J Clin Endocrinol Metab (2003) 0.98
Impaired glucose tolerance and insulinopenia in the GK-rat causes peripheral neuropathy. Diabetes Metab Res Rev (2002) 0.97
Diminished phosphodiesterase-8B potentiates biphasic insulin response to glucose. Endocrinology (2007) 0.96
Quality of interaction between primary health-care providers and patients with type 2 diabetes in Muscat, Oman: an observational study. BMC Fam Pract (2006) 0.96
Arachidonic acid is a physiological activator of the ryanodine receptor in pancreatic beta-cells. Cell Calcium (2006) 0.95
Effects of MCF2L2, ADIPOQ and SOX2 genetic polymorphisms on the development of nephropathy in type 1 Diabetes Mellitus. BMC Med Genet (2010) 0.94
Human neuropeptide Y signal peptide gain-of-function polymorphism is associated with increased body mass index: possible mode of function. Regul Pept (2005) 0.93
Pancreatic beta-cell mass or beta-cell function? That is the question! Diabetes Obes Metab (2008) 0.93
The possible mechanisms by which phanoside stimulates insulin secretion from rat islets. J Endocrinol (2007) 0.93
A novel insulin-releasing substance, phanoside, from the plant Gynostemma pentaphyllum. J Biol Chem (2004) 0.93
Dynamic changes in {beta}-cell mass and pancreatic insulin during the evolution of nutrition-dependent diabetes in psammomys obesus: impact of glycemic control. Diabetes (2005) 0.93
Psammomys obesus, a model for environment-gene interactions in type 2 diabetes. Diabetes (2005) 0.93
Hepatic glucocorticoid receptor antagonism is sufficient to reduce elevated hepatic glucose output and improve glucose control in animal models of type 2 diabetes. J Pharmacol Exp Ther (2005) 0.92
AMP-activated protein kinase (AMPK) mediates nutrient regulation of thioredoxin-interacting protein (TXNIP) in pancreatic beta-cells. PLoS One (2011) 0.91
Excessive islet NO generation in type 2 diabetic GK rats coincides with abnormal hormone secretion and is counteracted by GLP-1. PLoS One (2008) 0.91
Genetic association of adrenergic receptor alpha 2A with obesity and type 2 diabetes. Obesity (Silver Spring) (2013) 0.90
Sex-different hepaticglycogen content and glucose output in rats. BMC Biochem (2010) 0.90
Patients with Type 2 Diabetes Initiating Exenatide Twice Daily or Insulin in Clinical Practice: CHOICE Study. Diabetes Ther (2012) 0.89
Daily rhythm of glucose-induced insulin secretion by isolated islets from intact and pinealectomized rat. J Pineal Res (2002) 0.89
Estrogen signalling and the metabolic syndrome: targeting the hepatic estrogen receptor alpha action. PLoS One (2013) 0.89
Economic burden on families of childhood type 1 diabetes in urban Sudan. Diabetes Res Clin Pract (2005) 0.89
Enhanced endothelium-dependent vasodilatation by dual endothelin receptor blockade in individuals with insulin resistance. J Cardiovasc Pharmacol (2006) 0.89
Functional and genetic analysis in type 2 diabetes of liver X receptor alleles--a cohort study. BMC Med Genet (2009) 0.89
Combined treatment with exercise training and acarbose improves metabolic control and cardiovascular risk factor profile in subjects with mild type 2 diabetes. Diabetes Care (2006) 0.89
A stage model for assessing a community-based diabetes prevention program in Sweden. Health Promot Int (2002) 0.89
The influence of non-response in a population-based cohort study on type 2 diabetes evaluated by the Swedish Prescribed Drug Register. Eur J Epidemiol (2011) 0.88
Labisia pumila extract regulates body weight and adipokines in ovariectomized rats. Maturitas (2008) 0.88
Aged transgenic mice with increased glucocorticoid sensitivity in pancreatic beta-cells develop diabetes. Diabetes (2004) 0.88
Overexpression of protein-tyrosine phosphatase PTP sigma is linked to impaired glucose-induced insulin secretion in hereditary diabetic Goto-Kakizaki rats. Biochem Biophys Res Commun (2002) 0.87
Evaluation of genetic association and expression reduction of TRPC1 in the development of diabetic nephropathy. Am J Nephrol (2008) 0.87
Evaluation of IGFBP-7 DNA methylation changes and serum protein variation in Swedish subjects with and without type 2 diabetes. Clin Epigenetics (2013) 0.87
Activity of the plant peptide aglycin in mammalian systems. FEBS J (2007) 0.86
Glucose-regulated proinsulin gene expression is required for adequate insulin production during chronic glucose exposure. Endocrinology (2002) 0.86
Somatostatin receptor type 2 antagonism improves glucagon and corticosterone counterregulatory responses to hypoglycemia in streptozotocin-induced diabetic rats. Diabetes (2011) 0.86
Increased DNA methylation levels of the insulin-like growth factor binding protein 1 gene are associated with type 2 diabetes in Swedish men. Clin Epigenetics (2013) 0.86
Ryanodine receptor-operated activation of TRP-like channels can trigger critical Ca2+ signaling events in pancreatic beta-cells. FASEB J (2004) 0.86
Effects of glucagon-like peptide-1-(7-36)-amide on pancreatic islet and intestinal blood perfusion in Wistar rats and diabetic GK rats. Clin Sci (Lond) (2007) 0.86
Using Exenatide Twice Daily or Insulin in Clinical Practice: Results from CHOICE. Diabetes Ther (2013) 0.86
IGF-binding protein 1 and abdominal obesity in the development of type 2 diabetes in women. Eur J Endocrinol (2010) 0.86
Serum protein patterns in newly diagnosed type 2 diabetes mellitus--influence of diabetic environment and family history of diabetes. Diabetes Metab Res Rev (2008) 0.85
p57Kip2 (cdkn1c): sequence, splice variants and unique temporal and spatial expression pattern in the rat pancreas. Lab Invest (2005) 0.85
Antidiabetic Effect of Oral Borapetol B Compound, Isolated from the Plant Tinospora crispa, by Stimulating Insulin Release. Evid Based Complement Alternat Med (2013) 0.85
Estrogen receptor alpha gene variants associate with type 2 diabetes and fasting plasma glucose. Pharmacogenet Genomics (2008) 0.85
Improvement of ER stress-induced diabetes by stimulating autophagy. Autophagy (2013) 0.85
A cost-effectiveness analysis of a community-based diabetes prevention program in Sweden. Int J Technol Assess Health Care (2009) 0.85
Diet-induced diabetes in the sand rat (Psammomys obesus). Methods Mol Biol (2012) 0.85