Long term evaluation of disease progression through the quantitative magnetic resonance imaging of symptomatic knee osteoarthritis patients: correlation with clinical symptoms and radiographic changes.

PubWeight™: 2.00‹?› | Rank: Top 2%

🔗 View Article (PMC 1526551)

Published in Arthritis Res Ther on December 30, 2005

Authors

Jean-Pierre Raynauld1, Johanne Martel-Pelletier, Marie-Josée Berthiaume, Gilles Beaudoin, Denis Choquette, Boulos Haraoui, Hyman Tannenbaum, Joan M Meyer, John F Beary, Gary A Cline, Jean-Pierre Pelletier

Author Affiliations

1: Osteoarthritis Research Unit, University of Montreal Hospital Centre, Notre-Dame Hospital, Department of Medicine, University of Montreal, Montreal, Quebec, Canada. jp.raynauld@videotron.ca

Associated clinical trials:

Effect of Chondroitin Sulphate on Synovial Inflammation in Patients With Osteoarthritis of the Knee | NCT00604539

Articles citing this

Risk factors associated with the loss of cartilage volume on weight-bearing areas in knee osteoarthritis patients assessed by quantitative magnetic resonance imaging: a longitudinal study. Arthritis Res Ther (2007) 2.32

Change in MRI-detected subchondral bone marrow lesions is associated with cartilage loss: the MOST Study. A longitudinal multicentre study of knee osteoarthritis. Ann Rheum Dis (2008) 2.27

Tibiofemoral joint osteoarthritis: risk factors for MR-depicted fast cartilage loss over a 30-month period in the multicenter osteoarthritis study. Radiology (2009) 1.95

Most patients gain weight in the 2 years after total knee arthroplasty: comparison to a healthy control group. Osteoarthritis Cartilage (2009) 1.78

One year change of knee cartilage morphology in the first release of participants from the Osteoarthritis Initiative progression subcohort: association with sex, body mass index, symptoms and radiographic osteoarthritis status. Ann Rheum Dis (2008) 1.77

Systematic review of the concurrent and predictive validity of MRI biomarkers in OA. Osteoarthritis Cartilage (2011) 1.73

Two year longitudinal change and test-retest-precision of knee cartilage morphology in a pilot study for the osteoarthritis initiative. Osteoarthritis Cartilage (2007) 1.71

T1rho, T2 and focal knee cartilage abnormalities in physically active and sedentary healthy subjects versus early OA patients--a 3.0-Tesla MRI study. Eur Radiol (2008) 1.56

Cartilage imaging: motivation, techniques, current and future significance. Eur Radiol (2006) 1.51

Responsiveness and reliability of MRI in knee osteoarthritis: a meta-analysis of published evidence. Osteoarthritis Cartilage (2011) 1.46

Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis. Arthritis Res Ther (2007) 1.43

Bone marrow lesions predict site-specific cartilage defect development and volume loss: a prospective study in older adults. Arthritis Res Ther (2010) 1.38

Magnetic resonance imaging-based cartilage loss in painful contralateral knees with and without radiographic joint space narrowing: Data from the Osteoarthritis Initiative. Arthritis Rheum (2009) 1.34

Targeting subchondral bone for treating osteoarthritis: what is the evidence? Best Pract Res Clin Rheumatol (2010) 1.33

Novel fast semi-automated software to segment cartilage for knee MR acquisitions. Osteoarthritis Cartilage (2006) 1.24

Texture analysis of cartilage T2 maps: individuals with risk factors for OA have higher and more heterogeneous knee cartilage MR T2 compared to normal controls--data from the osteoarthritis initiative. Arthritis Res Ther (2011) 1.22

Obesity increases the prevalence and severity of focal knee abnormalities diagnosed using 3T MRI in middle-aged subjects--data from the Osteoarthritis Initiative. Skeletal Radiol (2011) 1.17

Imaging the painful osteoarthritic knee joint: what have we learned? Nat Clin Pract Rheumatol (2009) 1.14

MR imaging of cartilage and its repair in the knee--a review. Eur Radiol (2009) 1.12

Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double-blind, placebo-controlled pilot study using MRI. Ann Rheum Dis (2011) 1.12

Most recent developments in strategies to reduce the progression of structural changes in osteoarthritis: today and tomorrow. Arthritis Res Ther (2006) 1.11

Relationship of compartment-specific structural knee status at baseline with change in cartilage morphology: a prospective observational study using data from the osteoarthritis initiative. Arthritis Res Ther (2009) 1.09

The presence of meniscal lesions is a strong predictor of neuropathic pain in symptomatic knee osteoarthritis: a cross-sectional pilot study. Arthritis Res Ther (2014) 1.06

Meniscal extrusion or subchondral damage characterize incident accelerated osteoarthritis: Data from the Osteoarthritis Initiative. Clin Anat (2015) 1.03

Imaging of cartilage and bone: promises and pitfalls in clinical trials of osteoarthritis. Osteoarthritis Cartilage (2014) 1.00

Comparison of 1-year vs 2-year change in regional cartilage thickness in osteoarthritis results from 346 participants from the Osteoarthritis Initiative. Osteoarthritis Cartilage (2010) 0.99

Obesity and osteoarthritis: disease genesis and nonpharmacologic weight management. Rheum Dis Clin North Am (2008) 0.99

Co-localisation of non-cartilaginous articular pathology increases risk of cartilage loss in the tibiofemoral joint--the MOST study. Ann Rheum Dis (2012) 0.96

Knee cartilage loss in symptomatic knee osteoarthritis over 4.5 years. Arthritis Res Ther (2006) 0.96

Quantitative cartilage imaging in knee osteoarthritis. Arthritis (2010) 0.94

Osteoarthritis of the knee at 3.0 T: comparison of a quantitative and a semi-quantitative score for the assessment of the extent of cartilage lesion and bone marrow edema pattern in a 24-month longitudinal study. Skeletal Radiol (2011) 0.94

The effects of femoral graft placement on cartilage thickness after anterior cruciate ligament reconstruction. J Biomech (2013) 0.94

Knee meniscal extrusion in a largely non-osteoarthritic cohort: association with greater loss of cartilage volume. Arthritis Res Ther (2007) 0.92

T(2) relaxation time measurements are limited in monitoring progression, once advanced cartilage defects at the knee occur: longitudinal data from the osteoarthritis initiative. J Magn Reson Imaging (2013) 0.92

The evolution of articular cartilage imaging and its impact on clinical practice. Skeletal Radiol (2011) 0.92

Analysis of the precision and sensitivity to change of different approaches to assess cartilage loss by quantitative MRI in a longitudinal multicentre clinical trial in patients with knee osteoarthritis. Arthritis Res Ther (2008) 0.92

Radiographic joint space narrowing in osteoarthritis of the knee: relationship to meniscal tears and duration of pain. Skeletal Radiol (2008) 0.90

Quantification of cartilage loss in local regions of knee joints using semi-automated segmentation software: analysis of longitudinal data from the Osteoarthritis Initiative (OAI). Osteoarthritis Cartilage (2010) 0.88

The impact of MRI on the clinical management of inflammatory arthritides. Skeletal Radiol (2011) 0.88

How do short-term rates of femorotibial cartilage change compare to long-term changes? Four year follow-up data from the osteoarthritis initiative. Osteoarthritis Cartilage (2012) 0.87

Equivalence and precision of knee cartilage morphometry between different segmentation teams, cartilage regions, and MR acquisitions. Osteoarthritis Cartilage (2012) 0.87

Effects of diacerein at the molecular level in the osteoarthritis disease process. Ther Adv Musculoskelet Dis (2010) 0.86

Validity and sensitivity to change of three scales for the radiographic assessment of knee osteoarthritis using images from the Multicenter Osteoarthritis Study (MOST). Osteoarthritis Cartilage (2015) 0.82

Effect of 12 months treatment with chondroitin sulfate on cartilage volume in knee osteoarthritis patients: a randomized, double-blind, placebo-controlled pilot study using MRI. Clin Rheumatol (2012) 0.81

Use magnetic resonance imaging to assess articular cartilage. Ther Adv Musculoskelet Dis (2012) 0.81

Meniscal extrusion promotes knee osteoarthritis structural progression: protective effect of strontium ranelate treatment in a phase III clinical trial. Arthritis Res Ther (2015) 0.80

Comparison between different implementations of the 3D FLASH sequence for knee cartilage quantification. MAGMA (2011) 0.80

Association between meniscal tears and the peak external knee adduction moment and foot rotation during level walking in postmenopausal women without knee osteoarthritis: a cross-sectional study. Arthritis Res Ther (2008) 0.79

History of knee injury and MRI-assessed knee structures in middle- and older-aged adults: a cross-sectional study. Clin Rheumatol (2014) 0.78

Total Knee Replacement as a Knee Osteoarthritis Outcome: Predictors Derived from a 4-Year Long-Term Observation following a Randomized Clinical Trial Using Chondroitin Sulfate. Cartilage (2013) 0.78

Stem cells for the treatment of musculoskeletal pain. World J Stem Cells (2015) 0.77

A painful interface between normal aging and disease. J Gerontol A Biol Sci Med Sci (2007) 0.77

Change in knee cartilage volume in individuals completing a therapeutic exercise program for knee osteoarthritis. J Orthop Sports Phys Ther (2011) 0.77

Assessment of the Relationship between the Shape of the Lateral Meniscus and the Risk of Extrusion Based on MRI Examination of the Knee Joint. PLoS One (2016) 0.77

Does statin use have a disease modifying effect in symptomatic knee osteoarthritis? Study protocol for a randomised controlled trial. Trials (2015) 0.75

Does cartilage volume measurement or radiographic osteoarthritis at baseline independently predict ten-year cartilage volume loss? BMC Musculoskelet Disord (2016) 0.75

Change in knee structure and change in tibiofemoral joint space width: a five year longitudinal population-based study. BMC Musculoskelet Disord (2016) 0.75

Chondroitin sulfate efficacy versus celecoxib on knee osteoarthritis structural changes using magnetic resonance imaging: a 2-year multicentre exploratory study. Arthritis Res Ther (2016) 0.75

Natural history and clinical significance of meniscal tears over 8 years in a midlife cohort. BMC Musculoskelet Disord (2016) 0.75

Articles cited by this

The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care (1992) 144.02

Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol (1988) 35.68

Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum (1986) 29.12

Osteoarthritis: new insights. Part 1: the disease and its risk factors. Ann Intern Med (2000) 11.12

The association of bone marrow lesions with pain in knee osteoarthritis. Ann Intern Med (2001) 6.38

The clinical importance of meniscal tears demonstrated by magnetic resonance imaging in osteoarthritis of the knee. J Bone Joint Surg Am (2003) 3.39

Osteoarthritis: MR imaging findings in different stages of disease and correlation with clinical findings. Radiology (2003) 3.36

Meniscal tear and extrusion are strongly associated with progression of symptomatic knee osteoarthritis as assessed by quantitative magnetic resonance imaging. Ann Rheum Dis (2004) 2.89

Uncoupling of type II collagen synthesis and degradation predicts progression of joint damage in patients with knee osteoarthritis. Arthritis Rheum (2002) 2.66

Incidence and risk factors for radiographic knee osteoarthritis in middle-aged women: the Chingford Study. Arthritis Rheum (1999) 2.46

Rate of knee cartilage loss after partial meniscectomy. J Rheumatol (2002) 2.30

Cross sectional evaluation of biochemical markers of bone, cartilage, and synovial tissue metabolism in patients with knee osteoarthritis: relations with disease activity and joint damage. Ann Rheum Dis (2001) 2.18

Quantification of articular cartilage in the knee with pulsed saturation transfer subtraction and fat-suppressed MR imaging: optimization and validation. Radiology (1994) 2.05

Quantitative magnetic resonance imaging evaluation of knee osteoarthritis progression over two years and correlation with clinical symptoms and radiologic changes. Arthritis Rheum (2004) 2.01

Measurement of radiographic joint space width in the tibiofemoral compartment of the osteoarthritic knee: comparison of standing anteroposterior and Lyon schuss views. Arthritis Rheum (2003) 1.93

Knee cartilage defects: association with early radiographic osteoarthritis, decreased cartilage volume, increased joint surface area and type II collagen breakdown. Osteoarthritis Cartilage (2005) 1.82

Risk factors for progressive cartilage loss in the knee: a longitudinal magnetic resonance imaging study in forty-three patients. Arthritis Rheum (2002) 1.76

Accuracy and precision of joint space width measurements in standard and macroradiographs of osteoarthritic knees. Ann Rheum Dis (1995) 1.76

Tibial and femoral cartilage changes in knee osteoarthritis. Ann Rheum Dis (2001) 1.61

Weight loss: the treatment of choice for knee osteoarthritis? A randomized trial. Osteoarthritis Cartilage (2005) 1.53

Correlation between radiographically diagnosed osteophytes and magnetic resonance detected cartilage defects in the tibiofemoral joint. Ann Rheum Dis (1998) 1.46

Reliability of a quantification imaging system using magnetic resonance images to measure cartilage thickness and volume in human normal and osteoarthritic knees. Osteoarthritis Cartilage (2003) 1.41

Precision of joint space width measurement in knee osteoarthritis from digital image analysis of high definition macroradiographs. Osteoarthritis Cartilage (1993) 1.34

How does tibial cartilage volume relate to symptoms in subjects with knee osteoarthritis? Ann Rheum Dis (2004) 1.32

Effects of antiinflammatory drugs on the progression of osteoarthritis of the knee. LINK Study Group. Longitudinal Investigation of Nonsteroidal Antiinflammatory Drugs in Knee Osteoarthritis. J Rheumatol (1995) 1.30

The association of cartilage volume with knee pain. Osteoarthritis Cartilage (2003) 1.30

Quantitative microfocal radiographic assessment of osteoarthritis of the knee from weight bearing tunnel and semiflexed standing views. J Rheumatol (1994) 1.28

Computer-aided method for quantification of cartilage thickness and volume changes using MRI: validation study using a synthetic model. IEEE Trans Biomed Eng (2003) 1.22

Comparison and reproducibility of fast and conventional spoiled gradient-echo magnetic resonance sequences in the determination of knee cartilage volume. J Orthop Res (2000) 1.20

New radiographic-based surrogate outcome measures for osteoarthritis of the knee. Osteoarthritis Cartilage (2003) 1.18

Quantitative radiography of osteoarthritis. Ann Rheum Dis (1994) 1.15

Articular cartilage in the knee: mapping of the physiologic parameters at MR imaging with a local gradient coil--preliminary results. Radiology (1999) 1.13

Non-invasive determination of cartilage thickness throughout joint surfaces using magnetic resonance imaging. J Biomech (1997) 1.10

The natural history of emergent osteoarthritis of the knee in women. Osteoarthritis Cartilage (2002) 1.05

X-ray technologists' reproducibility from automated measurements of the medial tibiofemoral joint space width in knee osteoarthritis for a multicenter, multinational clinical trial. J Rheumatol (2003) 1.04

Correlation between radiographic severity of knee osteoarthritis and future disease progression. Results from a 3-year prospective, placebo-controlled study evaluating the effect of glucosamine sulfate. Osteoarthritis Cartilage (2003) 1.00

Precision of tibial cartilage morphometry with a coronal water-excitation MR sequence. Eur Radiol (2000) 0.95

A technique for 3D in vivo quantification of proton density and magnetization transfer coefficients of knee joint cartilage. Osteoarthritis Cartilage (2000) 0.93

Radiographic progression of knee osteoarthritis in a Czech cohort. Clin Exp Rheumatol (2000) 0.84

Articles by these authors

Treating rheumatoid arthritis to target: recommendations of an international task force. Ann Rheum Dis (2010) 10.97

Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy: a randomized, placebo-controlled, 52-week trial. Arthritis Rheum (2004) 6.55

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis. Nat Rev Rheumatol (2010) 5.14

The role of cytokines in osteoarthritis pathophysiology. Biorheology (2002) 4.28

Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthritis structural arthritis study. Arthritis Rheum (2006) 3.60

Neural circuitry underlying voluntary suppression of sadness. Biol Psychiatry (2003) 3.45

Risk factors associated with the loss of cartilage volume on weight-bearing areas in knee osteoarthritis patients assessed by quantitative magnetic resonance imaging: a longitudinal study. Arthritis Res Ther (2007) 2.32

Cyclooxygenase-2 and prostaglandins in articular tissues. Semin Arthritis Rheum (2003) 2.22

Safety and efficacy of long-term intraarticular steroid injections in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled trial. Arthritis Rheum (2003) 2.16

Canadian recommendations for use of methotrexate in patients with rheumatoid arthritis. J Rheumatol (2010) 2.11

Bone marrow lesions in people with knee osteoarthritis predict progression of disease and joint replacement: a longitudinal study. Rheumatology (Oxford) (2010) 2.05

Quantitative magnetic resonance imaging evaluation of knee osteoarthritis progression over two years and correlation with clinical symptoms and radiologic changes. Arthritis Rheum (2004) 2.01

Areas of brain activation in males and females during viewing of erotic film excerpts. Hum Brain Mapp (2002) 1.98

Cartilage in normal and osteoarthritis conditions. Best Pract Res Clin Rheumatol (2008) 1.95

Efficacy and safety of risedronate 150 mg once a month in the treatment of postmenopausal osteoporosis. Bone (2007) 1.94

The tryptophan hydroxylase inhibitor LX1031 shows clinical benefit in patients with nonconstipating irritable bowel syndrome. Gastroenterology (2011) 1.88

Meniscal tear as an osteoarthritis risk factor in a largely non-osteoarthritic cohort: a cross-sectional study. J Rheumatol (2007) 1.84

The association between subchondral bone cysts and tibial cartilage volume and risk of joint replacement in people with knee osteoarthritis: a longitudinal study. Arthritis Res Ther (2010) 1.83

Method of propulsion of a ferromagnetic core in the cardiovascular system through magnetic gradients generated by an MRI system. IEEE Trans Biomed Eng (2006) 1.81

Diagnostic imaging of spinal deformities: reducing patients radiation dose with a new slot-scanning X-ray imager. Spine (Phila Pa 1976) (2010) 1.77

The Canadian Early Arthritis Cohort (CATCH): patients with new-onset synovitis meeting the 2010 ACR/EULAR classification criteria but not the 1987 ACR classification criteria present with less severe disease activity. J Rheumatol (2012) 1.61

Increasing treatment in early rheumatoid arthritis is not determined by the disease activity score but by physician global assessment: results from the CATCH study. J Rheumatol (2012) 1.60

Time to disease-modifying antirheumatic drug treatment in rheumatoid arthritis and its predictors: a national, multicenter, retrospective cohort. J Rheumatol (2012) 1.60

"Change the mind and you change the brain": effects of cognitive-behavioral therapy on the neural correlates of spider phobia. Neuroimage (2003) 1.59

Treating to a target in established active rheumatoid arthritis patients receiving a tumor necrosis factor inhibitor: results from a real-world cluster-randomized adalimumab trial. Arthritis Care Res (Hoboken) (2013) 1.57

Adalimumab significantly reduces both spinal and sacroiliac joint inflammation in patients with ankylosing spondylitis: a multicenter, randomized, double-blind, placebo-controlled study. Arthritis Rheum (2007) 1.56

Missing Anticitrullinated Protein Antibody Does Not Affect Short-term Outcomes in Early Inflammatory Arthritis: From the Canadian Early Arthritis Cohort. J Rheumatol (2015) 1.50

Interstitial pneumonitis associated with infliximab therapy. J Rheumatol (2006) 1.49

Lack of seroconversion of rheumatoid factor and anti-cyclic citrullinated peptide in patients with early inflammatory arthritis: a systematic literature review. Rheumatology (Oxford) (2010) 1.49

The Canadian Rheumatology Association/ Spondyloarthritis Research Consortium of Canada treatment recommendations for the management of spondyloarthritis: a national multidisciplinary stakeholder project. J Rheumatol (2007) 1.44

Early management of newly diagnosed rheumatoid arthritis by Canadian rheumatologists: a national, multicenter, retrospective cohort. J Rheumatol (2011) 1.43

Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes. BMC Musculoskelet Disord (2009) 1.40

Canadian recommendations for clinical trials of pharmacologic interventions in rheumatoid arthritis: inclusion criteria and study design. J Rheumatol (2011) 1.40

Canadian Rheumatology Association recommendations for pharmacological management of rheumatoid arthritis with traditional and biologic disease-modifying antirheumatic drugs. J Rheumatol (2011) 1.40

Bone marrow lesions predict site-specific cartilage defect development and volume loss: a prospective study in older adults. Arthritis Res Ther (2010) 1.38

Development of musculoskeletal toxicity without clear benefit after administration of PG-116800, a matrix metalloproteinase inhibitor, to patients with knee osteoarthritis: a randomized, 12-month, double-blind, placebo-controlled study. Arthritis Res Ther (2007) 1.37

Targeting subchondral bone for treating osteoarthritis: what is the evidence? Best Pract Res Clin Rheumatol (2010) 1.33

Effect of risedronate on joint structure and symptoms of knee osteoarthritis: results of the BRISK randomized, controlled trial [ISRCTN01928173]. Arthritis Res Ther (2005) 1.30

Differential gene expression and regulation of the bone morphogenetic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts. Arthritis Rheum (2004) 1.25

High mobility group box 1 potentiates the pro-inflammatory effects of interleukin-1β in osteoarthritic synoviocytes. Arthritis Res Ther (2010) 1.24

In vivo selective inhibition of mitogen-activated protein kinase kinase 1/2 in rabbit experimental osteoarthritis is associated with a reduction in the development of structural changes. Arthritis Rheum (2003) 1.24

Computer-aided method for quantification of cartilage thickness and volume changes using MRI: validation study using a synthetic model. IEEE Trans Biomed Eng (2003) 1.22

Degradation of small leucine-rich repeat proteoglycans by matrix metalloprotease-13: identification of a new biglycan cleavage site. Arthritis Res Ther (2006) 1.19

Apparent diffusion coefficient of intervertebral discs related to matrix composition and integrity. Magn Reson Imaging (2004) 1.19

Characterization of cardiac-related noise in fMRI of the cervical spinal cord. Magn Reson Imaging (2008) 1.18

Ten years in the life of an enzyme: the story of the human MMP-13 (collagenase-3). Mod Rheumatol (2004) 1.17

The inhibition of subchondral bone resorption in the early phase of experimental dog osteoarthritis by licofelone is associated with a reduction in the synthesis of MMP-13 and cathepsin K. Bone (2004) 1.17

Interleukin 17 (IL-17) induces collagenase-3 production in human osteoarthritic chondrocytes via AP-1 dependent activation: differential activation of AP-1 members by IL-17 and IL-1beta. J Rheumatol (2002) 1.15

Diffusion-weighted MR imaging of the liver of hepatitis C patients. NMR Biomed (2003) 1.15

Neural correlates of lexical and sublexical processes in reading. Brain Lang (2004) 1.15

Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double-blind, placebo-controlled pilot study using MRI. Ann Rheum Dis (2011) 1.12

Most recent developments in strategies to reduce the progression of structural changes in osteoarthritis: today and tomorrow. Arthritis Res Ther (2006) 1.11

Methotrexate drug interactions in the treatment of rheumatoid arthritis: a systematic review. J Rheumatol (2010) 1.11

Comparison of two referral strategies for diagnosis of axial spondyloarthritis: the Recognising and Diagnosing Ankylosing Spondylitis Reliably (RADAR) study. Ann Rheum Dis (2012) 1.11

Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model. Arthritis Res Ther (2011) 1.11

Pioglitazone, a peroxisome proliferator-activated receptor gamma agonist, reduces the progression of experimental osteoarthritis in guinea pigs. Arthritis Rheum (2005) 1.11

Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1. J Biol Chem (2004) 1.09

DMOAD developments: present and future. Bull NYU Hosp Jt Dis (2007) 1.09

PPARgamma ligands as modulators of inflammatory and catabolic responses in arthritis. An overview. J Rheumatol (2002) 1.08

Synthesis of interleukin 1beta, tumor necrosis factor-alpha, and interstitial collagenase (MMP-1) is eicosanoid dependent in human osteoarthritis synovial membrane explants: interactions with antiinflammatory cytokines. J Rheumatol (2002) 1.07