Rui Sousa

Author PubWeight™ 35.93‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Structural basis of interdomain communication in the Hsc70 chaperone. Mol Cell 2005 3.34
2 Structural basis of J cochaperone binding and regulation of Hsp70. Mol Cell 2007 2.14
3 Structure of the Hsp110:Hsc70 nucleotide exchange machine. Mol Cell 2008 1.96
4 Characterization of Hsp70 binding and nucleotide exchange by the yeast Hsp110 chaperone Sse1. Biochemistry 2006 1.34
5 The structure of CCT-Hsc70 NBD suggests a mechanism for Hsp70 delivery of substrates to the chaperonin. Nat Struct Mol Biol 2008 1.29
6 Structure-function analysis of the auxilin J-domain reveals an extended Hsc70 interaction interface. Biochemistry 2003 1.18
7 Structural transitions mediating transcription initiation by T7 RNA polymerase. Cell 2002 1.14
8 Translocation by T7 RNA polymerase: a sensitively poised Brownian ratchet. J Mol Biol 2006 1.08
9 Discontinuous movement and conformational change during pausing and termination by T7 RNA polymerase. EMBO J 2003 1.08
10 A promoter recognition mechanism common to yeast mitochondrial and phage t7 RNA polymerases. J Biol Chem 2009 1.03
11 ATP-induced conformational changes in Hsp70: molecular dynamics and experimental validation of an in silico predicted conformation. Biochemistry 2009 1.03
12 A Y639F/H784A T7 RNA polymerase double mutant displays superior properties for synthesizing RNAs with non-canonical NTPs. Nucleic Acids Res 2002 1.02
13 Dynamic interactions between clathrin and locally structured elements in a disordered protein mediate clathrin lattice assembly. J Mol Biol 2010 0.98
14 Major conformational changes during T7RNAP transcription initiation coincide with, and are required for, promoter release. J Mol Biol 2005 0.95
15 Crystallization of a functionally intact Hsc70 chaperone. Acta Crystallogr Sect F Struct Biol Cryst Commun 2005 0.94
16 Functional architecture of T7 RNA polymerase transcription complexes. J Mol Biol 2007 0.93
17 Weakening of the T7 promoter-polymerase interaction facilitates promoter release. J Biol Chem 2005 0.90
18 Multiple roles for the T7 promoter nontemplate strand during transcription initiation and polymerase release. J Biol Chem 2004 0.90
19 Molecular dynamics studies of the energetics of translocation in model T7 RNA polymerase elongation complexes. Proteins 2008 0.89
20 Phenotype-genotype profiles in Crohn's disease predicted by genetic markers in autophagy-related genes (GOIA study II). Inflamm Bowel Dis 2013 0.89
21 Expression and purification of E. coli BirA biotin ligase for in vitro biotinylation. Protein Expr Purif 2012 0.87
22 Conservation of promoter melting mechanisms in divergent regions of the single-subunit RNA polymerases. Biochemistry 2012 0.86
23 Role of T7 RNA polymerase His784 in start site selection and initial transcription. Biochemistry 2002 0.85
24 A role for an Hsp70 nucleotide exchange factor in the regulation of synaptic vesicle endocytosis. J Neurosci 2013 0.85
25 Use of Site-Specifically Tethered Chemical Nucleases to Study Macromolecular Reactions. Biol Proced Online 2003 0.83
26 Evaluation of competing J domain:Hsp70 complex models in light of existing mutational and NMR data. Proc Natl Acad Sci U S A 2012 0.81
27 Mechanism of T7 RNAP pausing and termination at the T7 concatemer junction: a local change in transcription bubble structure drives a large change in transcription complex architecture. J Mol Biol 2007 0.78
28 [Enteric nutrition and esophageal impactation: what relationship]. Acta Med Port 2010 0.77
29 Comment on "Xeno's paradox". EMBO Rep 2009 0.75
30 Novel system for in vivo biotinylation and its application to crab antimicrobial protein scygonadin. Biotechnol Lett 2012 0.75
31 The thumb subdomain of yeast mitochondrial RNA polymerase is involved in processivity, transcript fidelity and mitochondrial transcription factor binding. RNA Biol 2015 0.75
32 Comment on Frank Gannon's EMBO reports editorial "address bias". EMBO Rep 2007 0.75
33 Research funding: less should be more. Science 2008 0.75
34 Bioequivalence of eslicarbazepine acetate from two different sources of its active product ingredient in healthy subjects. Drugs R D 2013 0.75
35 [8] Using cosolvents to stabilize protein conformation for crystallization. Methods Enzymol 1997 0.75
36 Hepatic hydatid cyst: a non-surgical approach. Rev Soc Bras Med Trop 2012 0.75