Published in Bone on March 10, 2006
Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice. J Clin Invest (2008) 1.81
Leptin and the sympathetic connection of fat to bone. Osteoporos Int (2007) 1.61
Mice lacking beta-adrenergic receptors have increased bone mass but are not protected from deleterious skeletal effects of ovariectomy. Endocrinology (2008) 1.07
Amelioration of type I diabetes-induced osteoporosis by parathyroid hormone is associated with improved osteoblast survival. J Cell Physiol (2012) 0.91
Low dose of propranolol down-modulates bone resorption by inhibiting inflammation and osteoclast differentiation. Br J Pharmacol (2012) 0.87
Anticipating bipedalism: trabecular organization in the newborn ilium. J Anat (2009) 0.85
The role of mast cells in parathyroid bone disease. J Bone Miner Res (2010) 0.85
Sympathetic Skin Response and Vasomotor Symptoms in Postmenopausal Osteoporotic Women. Int J Community Based Nurs Midwifery (2015) 0.78
The effects of antihypertensive drugs on bone mineral density in ovariectomized mice. J Korean Med Sci (2013) 0.76
Propranolol Prevents Osteoporosis and up-regulates Leptin in Ovariectomized Rats. Iran J Pharm Res (2013) 0.76
The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis. N Engl J Med (2003) 7.25
The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. N Engl J Med (2004) 6.55
In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography. J Clin Endocrinol Metab (2005) 5.31
Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization. J Biol Chem (2002) 4.52
BMP type I receptor inhibition reduces heterotopic [corrected] ossification. Nat Med (2008) 4.20
Mechanisms of disease: is osteoporosis the obesity of bone? Nat Clin Pract Rheumatol (2006) 4.18
Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sites. J Bone Miner Res (2004) 4.02
Essential role of beta-catenin in postnatal bone acquisition. J Biol Chem (2005) 3.88
The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development. J Clin Invest (2007) 3.76
High bone mass in mice expressing a mutant LRP5 gene. J Bone Miner Res (2003) 3.48
Age-related changes in trabecular architecture differ in female and male C57BL/6J mice. J Bone Miner Res (2007) 3.38
Finite element analysis based on in vivo HR-pQCT images of the distal radius is associated with wrist fracture in postmenopausal women. J Bone Miner Res (2008) 3.33
Fibroblast growth factor-23 relationship to dietary phosphate and renal phosphate handling in healthy young men. J Clin Endocrinol Metab (2004) 2.83
Increasing occurrence of atypical femoral fractures associated with bisphosphonate use. Arch Intern Med (2012) 2.53
Relation of body composition, fat mass, and serum lipids to osteoporotic fractures and bone mineral density in Chinese men and women. Am J Clin Nutr (2006) 2.52
Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis. JAMA (2008) 2.52
Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6. J Bone Miner Res (2004) 2.46
Bisphosphonate-associated osteonecrosis of the jaw: a key role of inflammation? Bone (2009) 2.44
Clinical use of quantitative computed tomography and peripheral quantitative computed tomography in the management of osteoporosis in adults: the 2007 ISCD Official Positions. J Clin Densitom (2008) 2.21
Contribution of in vivo structural measurements and load/strength ratios to the determination of forearm fracture risk in postmenopausal women. J Bone Miner Res (2007) 2.11
Compromised bone microarchitecture and estimated bone strength in young adults with cystic fibrosis. J Clin Endocrinol Metab (2014) 2.08
Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage. Proc Natl Acad Sci U S A (2008) 1.98
Structural determinants of vertebral fracture risk. J Bone Miner Res (2007) 1.97
Improving evaluation and treatment for osteoporosis following distal radial fractures. A prospective randomized intervention. J Bone Joint Surg Am (2008) 1.88
Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice. J Clin Invest (2004) 1.82
Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice. J Clin Invest (2008) 1.81
Effect of music-based multitask training on gait, balance, and fall risk in elderly people: a randomized controlled trial. Arch Intern Med (2010) 1.78
Effect of denosumab treatment on the risk of fractures in subgroups of women with postmenopausal osteoporosis. J Bone Miner Res (2012) 1.78
Congenic strains of mice for verification and genetic decomposition of quantitative trait loci for femoral bone mineral density. J Bone Miner Res (2003) 1.78
Bone structure at the distal radius during adolescent growth. J Bone Miner Res (2009) 1.74
Regulation of beta catenin signaling and parathyroid hormone anabolic effects in bone by the matricellular protein periostin. Proc Natl Acad Sci U S A (2012) 1.68
Caloric restriction leads to high marrow adiposity and low bone mass in growing mice. J Bone Miner Res (2010) 1.66
Primary hyperparathyroidism: can parathyroid carcinoma be anticipated on clinical and biochemical grounds? Report of nine cases and review of the literature. Ann Surg Oncol (2005) 1.66
Bone quality: where do we go from here? Osteoporos Int (2003) 1.64
Suppression of Wnt signaling by Dkk1 attenuates PTH-mediated stromal cell response and new bone formation. Cell Metab (2010) 1.62
Proximal femoral structure and the prediction of hip fracture in men: a large prospective study using QCT. J Bone Miner Res (2008) 1.55
Congenic mice with low serum IGF-I have increased body fat, reduced bone mineral density, and an altered osteoblast differentiation program. Bone (2004) 1.53
Comparative effects of teriparatide, denosumab, and combination therapy on peripheral compartmental bone density, microarchitecture, and estimated strength: the DATA-HRpQCT Study. J Bone Miner Res (2015) 1.50
PPARG by dietary fat interaction influences bone mass in mice and humans. J Bone Miner Res (2008) 1.50
A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength. Proc Natl Acad Sci U S A (2012) 1.48
Clinical evaluation of medicinal products for acceleration of fracture healing in patients with osteoporosis. Bone (2008) 1.48
Effects of cast-mediated immobilization on bone mineral mass at various sites in adolescents with lower-extremity fracture. J Bone Joint Surg Am (2012) 1.45
Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation. Proc Natl Acad Sci U S A (2008) 1.45
A soluble activin type IIA receptor induces bone formation and improves skeletal integrity. Proc Natl Acad Sci U S A (2008) 1.42
The matricellular protein periostin is required for sost inhibition and the anabolic response to mechanical loading and physical activity. J Biol Chem (2009) 1.41
beta-Arrestin2 regulates the differential response of cortical and trabecular bone to intermittent PTH in female mice. J Bone Miner Res (2004) 1.39
Megakaryocyte-osteoblast interaction revealed in mice deficient in transcription factors GATA-1 and NF-E2. J Bone Miner Res (2003) 1.39
The ternary IGF complex influences postnatal bone acquisition and the skeletal response to intermittent parathyroid hormone. J Endocrinol (2006) 1.37
Lifelong accumulation of bone in mice lacking Pten in osteoblasts. Proc Natl Acad Sci U S A (2007) 1.36
The importance and relevance of peak bone mass in the prevalence of osteoporosis. Salud Publica Mex (2009) 1.34
Direct percutaneous gene delivery to enhance healing of segmental bone defects. J Bone Joint Surg Am (2006) 1.32
Denosumab. Nat Rev Drug Discov (2010) 1.31
Childhood fractures are associated with decreased bone mass gain during puberty: an early marker of persistent bone fragility? J Bone Miner Res (2006) 1.30
Sclerostin antibody inhibits skeletal deterioration due to reduced mechanical loading. J Bone Miner Res (2013) 1.29
Deletion of β-adrenergic receptor 1, 2, or both leads to different bone phenotypes and response to mechanical stimulation. J Bone Miner Res (2012) 1.29
Strontium ranelate treatment improves trabecular and cortical intrinsic bone tissue quality, a determinant of bone strength. J Bone Miner Res (2007) 1.28
Efficacy of risedronate on clinical vertebral fractures within six months. Curr Med Res Opin (2004) 1.28
A bone structural basis for fracture risk in diabetes. J Clin Endocrinol Metab (2008) 1.26
Population-based analysis of the relationship of whole bone strength indices and fall-related loads to age- and sex-specific patterns of hip and wrist fractures. J Bone Miner Res (2005) 1.24
Serum complexes of insulin-like growth factor-1 modulate skeletal integrity and carbohydrate metabolism. FASEB J (2008) 1.23
Determinants of bone microarchitecture and mechanical properties in obese men. J Clin Endocrinol Metab (2012) 1.21
A single percutaneous injection of recombinant human bone morphogenetic protein-2 accelerates fracture repair. J Bone Joint Surg Am (2003) 1.21
Selective ligand-induced stabilization of active and desensitized parathyroid hormone type 1 receptor conformations. J Biol Chem (2002) 1.21
Caloric restriction decreases cortical bone mass but spares trabecular bone in the mouse skeleton: implications for the regulation of bone mass by body weight. J Bone Miner Res (2008) 1.20
Inhibiting activin-A signaling stimulates bone formation and prevents cancer-induced bone destruction in vivo. J Bone Miner Res (2010) 1.18
Extracellular post-translational modifications of collagen are major determinants of biomechanical properties of fetal bovine cortical bone. Bone (2005) 1.17
Bone loss after bariatric surgery: discordant results between DXA and QCT bone density. J Bone Miner Res (2014) 1.16
Theoretical implications of the biomechanical fracture threshold. J Bone Miner Res (2008) 1.16
Association of circulating sclerostin with bone mineral mass, microstructure, and turnover biochemical markers in healthy elderly men and women. J Clin Endocrinol Metab (2013) 1.14
Hypoxia-inducible factors 1alpha and 2alpha exert both distinct and overlapping functions in long bone development. J Cell Biochem (2010) 1.12
Health professional's guide to rehabilitation of the patient with osteoporosis. Osteoporos Int (2003) 1.11
Bone microarchitecture is impaired in adolescent amenorrheic athletes compared with eumenorrheic athletes and nonathletic controls. J Clin Endocrinol Metab (2011) 1.11
Comparison of skeletal effects of ovariectomy versus chemically induced ovarian failure in mice. J Bone Miner Res (2008) 1.11
Are osteoclasts needed for the bone anabolic response to parathyroid hormone? A study of intermittent parathyroid hormone with denosumab or alendronate in knock-in mice expressing humanized RANKL. J Biol Chem (2010) 1.10
Predicting the failure load of the distal radius. Osteoporos Int (2003) 1.09
A soluble activin receptor Type IIA fusion protein (ACE-011) increases bone mass via a dual anabolic-antiresorptive effect in Cynomolgus monkeys. Bone (2010) 1.08
Impact of seafood and fruit consumption on bone mineral density. Maturitas (2006) 1.07
A proteasome inhibitor, bortezomib, inhibits breast cancer growth and reduces osteolysis by downregulating metastatic genes. Clin Cancer Res (2010) 1.07
In vivo targeted deletion of calpain small subunit, Capn4, in cells of the osteoblast lineage impairs cell proliferation, differentiation, and bone formation. J Biol Chem (2008) 1.06
Microarchitecture influences microdamage accumulation in human vertebral trabecular bone. J Bone Miner Res (2008) 1.06
Biomechanics of vertebral fractures and the vertebral fracture cascade. Curr Osteoporos Rep (2010) 1.06
Neuropeptide Y knockout mice reveal a central role of NPY in the coordination of bone mass to body weight. PLoS One (2009) 1.04
Evaluation of symptomatic slow-acting drugs in osteoarthritis using the GRADE system. BMC Musculoskelet Disord (2008) 1.04
Bone safety of long-term bisphosphonate treatment. Curr Med Res Opin (2004) 1.03
Multicenter precision of cortical and trabecular bone quality measures assessed by high-resolution peripheral quantitative computed tomography. J Bone Miner Res (2013) 1.02
Role of trabecular microarchitecture and its heterogeneity parameters in the mechanical behavior of ex vivo human L3 vertebrae. J Bone Miner Res (2010) 1.02
The heparin-binding domain of IGFBP-2 has insulin-like growth factor binding-independent biologic activity in the growing skeleton. J Biol Chem (2011) 1.02
Differences in skeletal microarchitecture and strength in African-American and white women. J Bone Miner Res (2013) 1.02
Specimen size and porosity can introduce error into microCT-based tissue mineral density measurements. Bone (2008) 1.01
Joint Official Positions of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX(®). Executive Summary of the 2010 Position Development Conference on Interpretation and use of FRAX® in clinical practice. J Clin Densitom (2011) 1.00
The effect of thoracic kyphosis and sagittal plane alignment on vertebral compressive loading. J Bone Miner Res (2012) 0.99
Trochanteric soft tissue thickness and hip fracture in older men. J Clin Endocrinol Metab (2008) 0.99
Mechanical contributions of the cortical and trabecular compartments contribute to differences in age-related changes in vertebral body strength in men and women assessed by QCT-based finite element analysis. J Bone Miner Res (2011) 0.99
Dietary protein and bone health. J Bone Miner Res (2004) 0.99
Two-year changes in bone density after Roux-en-Y gastric bypass surgery. J Clin Endocrinol Metab (2015) 0.99
Altered thermogenesis and impaired bone remodeling in Misty mice. J Bone Miner Res (2013) 0.99
Variations of CT-based trunk muscle attenuation by age, sex, and specific muscle. J Gerontol A Biol Sci Med Sci (2012) 0.99