Elizabeth A Komives

Author PubWeight™ 84.75‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Localizing frustration in native proteins and protein assemblies. Proc Natl Acad Sci U S A 2007 2.33
2 Biophysical characterization of the free IkappaBalpha ankyrin repeat domain in solution. Protein Sci 2004 1.89
3 Regions of IkappaBalpha that are critical for its inhibition of NF-kappaB.DNA interaction fold upon binding to NF-kappaB. Proc Natl Acad Sci U S A 2006 1.86
4 An unexpected twist in viral capsid maturation. Nature 2009 1.80
5 Automated extraction of backbone deuteration levels from amide H/2H mass spectrometry experiments. Protein Sci 2006 1.75
6 The energy landscape of modular repeat proteins: topology determines folding mechanism in the ankyrin family. J Mol Biol 2005 1.60
7 Thermodynamics reveal that helix four in the NLS of NF-kappaB p65 anchors IkappaBalpha, forming a very stable complex. J Mol Biol 2006 1.59
8 Stabilizing IkappaBalpha by "consensus" design. J Mol Biol 2006 1.53
9 Transfer of flexibility between ankyrin repeats in IkappaB* upon formation of the NF-kappaB complex. J Mol Biol 2008 1.44
10 Kinetic enhancement of NF-kappaBxDNA dissociation by IkappaBalpha. Proc Natl Acad Sci U S A 2009 1.39
11 On the role of frustration in the energy landscapes of allosteric proteins. Proc Natl Acad Sci U S A 2011 1.39
12 Identification of high levels of phytochelatins, glutathione and cadmium in the phloem sap of Brassica napus. A role for thiol-peptides in the long-distance transport of cadmium and the effect of cadmium on iron translocation. Plant J 2008 1.38
13 Amide H/2H exchange reveals communication between the cAMP and catalytic subunit-binding sites in the R(I)alpha subunit of protein kinase A. J Mol Biol 2002 1.36
14 Pre-folding IkappaBalpha alters control of NF-kappaB signaling. J Mol Biol 2008 1.35
15 Epitope mapping of a monoclonal antibody against human thrombin by H/D-exchange mass spectrometry reveals selection of a diverse sequence in a highly conserved protein. Protein Sci 2002 1.35
16 Allosteric networks in thrombin distinguish procoagulant vs. anticoagulant activities. Proc Natl Acad Sci U S A 2012 1.33
17 Folding landscapes of ankyrin repeat proteins: experiments meet theory. Curr Opin Struct Biol 2008 1.31
18 Molecular mechanisms of system control of NF-kappaB signaling by IkappaBalpha. Biochemistry 2010 1.25
19 The energy landscapes of repeat-containing proteins: topology, cooperativity, and the folding funnels of one-dimensional architectures. PLoS Comput Biol 2008 1.25
20 An improved grafting technique for mature Arabidopsis plants demonstrates long-distance shoot-to-root transport of phytochelatins in Arabidopsis. Plant Physiol 2006 1.21
21 Ligand-induced conformational changes in the acetylcholine-binding protein analyzed by hydrogen-deuterium exchange mass spectrometry. J Biol Chem 2006 1.20
22 Enhanced conformational space sampling improves the prediction of chemical shifts in proteins. J Am Chem Soc 2010 1.18
23 The IkappaBalpha/NF-kappaB complex has two hot spots, one at either end of the interface. Protein Sci 2008 1.15
24 Solvent accessibility of protein surfaces by amide H/2H exchange MALDI-TOF mass spectrometry. J Am Soc Mass Spectrom 2006 1.15
25 Functional dynamics of the folded ankyrin repeats of I kappa B alpha revealed by nuclear magnetic resonance. Biochemistry 2009 1.14
26 Identification of the protein kinase A regulatory RIalpha-catalytic subunit interface by amide H/2H exchange and protein docking. Proc Natl Acad Sci U S A 2003 1.12
27 Two apolipoprotein E mimetic peptides, ApoE(130-149) and ApoE(141-155)2, bind to LRP1. Biochemistry 2004 1.11
28 Interactions of the NPXY microdomains of the low density lipoprotein receptor-related protein 1. Proteomics 2009 1.07
29 Visualization of the nanospring dynamics of the IkappaBalpha ankyrin repeat domain in real time. Proc Natl Acad Sci U S A 2011 1.06
30 Solvent exposed non-contacting amino acids play a critical role in NF-kappaB/IkappaBalpha complex formation. J Mol Biol 2002 1.05
31 Thrombomodulin tightens the thrombin active site loops to promote protein C activation. Biochemistry 2005 1.04
32 Allosteric changes in solvent accessibility observed in thrombin upon active site occupation. Biochemistry 2004 1.04
33 Critical salt bridges guide capsid assembly, stability, and maturation behavior in bacteriophage HK97. Mol Cell Proteomics 2010 1.01
34 Direct observation of a transient ternary complex during IκBα-mediated dissociation of NF-κB from DNA. Proc Natl Acad Sci U S A 2013 0.98
35 The dynamic structure of thrombin in solution. Biophys J 2012 0.98
36 Induced fit, folding, and recognition of the NF-kappaB-nuclear localization signals by IkappaBalpha and IkappaBbeta. J Mol Biol 2006 0.97
37 Direct analysis of the kinetic profiles of organophosphate-acetylcholinesterase adducts by MALDI-TOF mass spectrometry. Biochemistry 2003 0.96
38 ARS5 is a component of the 26S proteasome complex, and negatively regulates thiol biosynthesis and arsenic tolerance in Arabidopsis. Plant J 2009 0.95
39 Structure of the minimal interface between ApoE and LRP. J Mol Biol 2010 0.95
40 HK97 maturation studied by crystallography and H/2H exchange reveals the structural basis for exothermic particle transitions. J Mol Biol 2010 0.94
41 The plastic landscape of repeat proteins. Proc Natl Acad Sci U S A 2007 0.94
42 Structural and functional consequences of tyrosine phosphorylation in the LRP1 cytoplasmic domain. J Biol Chem 2008 0.93
43 Decoding of lipoprotein-receptor interactions: properties of ligand binding modules governing interactions with apolipoprotein E. Biochemistry 2010 0.92
44 Methods for studying transmembrane peptides in bicelles: consequences of hydrophobic mismatch and peptide sequence. J Magn Reson 2002 0.92
45 Prediction of native-state hydrogen exchange from perfectly funneled energy landscapes. J Am Chem Soc 2011 0.92
46 Two different proteins that compete for binding to thrombin have opposite kinetic and thermodynamic profiles. Protein Sci 2004 0.91
47 Discrete kinetic models from funneled energy landscape simulations. PLoS One 2012 0.91
48 Folding kinetics of the cooperatively folded subdomain of the IκBα ankyrin repeat domain. J Mol Biol 2011 0.90
49 The RelA nuclear localization signal folds upon binding to IκBα. J Mol Biol 2010 0.89
50 Thermodynamic compensation upon binding to exosite 1 and the active site of thrombin. Biochemistry 2011 0.88
51 R-subunit isoform specificity in protein kinase A: distinct features of protein interfaces in PKA types I and II by amide H/2H exchange mass spectrometry. J Mol Biol 2007 0.88
52 NMR structures reveal how oxidation inactivates thrombomodulin. Biochemistry 2003 0.87
53 Correlated motions and residual frustration in thrombin. J Phys Chem B 2013 0.87
54 The structure, dynamics, and binding of the LA45 module pair of the low-density lipoprotein receptor suggest an important role for LA4 in ligand release. Biochemistry 2011 0.87
55 Predicted disorder-to-order transition mutations in IκBα disrupt function. Phys Chem Chem Phys 2014 0.87
56 Detection of a ternary complex of NF-kappaB and IkappaBalpha with DNA provides insights into how IkappaBalpha removes NF-kappaB from transcription sites. Proc Natl Acad Sci U S A 2011 0.86
57 Expanding proteome coverage with orthogonal-specificity α-lytic proteases. Mol Cell Proteomics 2014 0.86
58 Role of disorder in IκB-NFκB interaction. IUBMB Life 2012 0.86
59 Amide H/2H exchange reveals a mechanism of thrombin activation. Biochemistry 2006 0.86
60 Hydrogen-exchange mass spectrometry for the study of intrinsic disorder in proteins. Biochim Biophys Acta 2012 0.86
61 All three LDL receptor homology regions of the LDL receptor-related protein bind multiple ligands. Biochemistry 2003 0.86
62 Identification of an arsenic tolerant double mutant with a thiol-mediated component and increased arsenic tolerance in phyA mutants. Plant J 2007 0.86
63 Consequences of IkappaB alpha hydroxylation by the factor inhibiting HIF (FIH). FEBS Lett 2010 0.85
64 Measurement of solvent accessibility at protein-protein interfaces. Methods Mol Biol 2005 0.85
65 Structural and functional consequences of methionine oxidation in thrombomodulin. Biochim Biophys Acta 2005 0.84
66 Mutations in the fourth EGF-like domain affect thrombomodulin-induced changes in the active site of thrombin. Biochemistry 2008 0.84
67 Long-range effects and functional consequences of stabilizing mutations in the ankyrin repeat domain of IκBα. J Mol Biol 2012 0.83
68 Rapid mass spectrometric analysis of 15N-Leu incorporation fidelity during preparation of specifically labeled NMR samples. Protein Sci 2008 0.83
69 Single-molecule FRET reveals the native-state dynamics of the IκBα ankyrin repeat domain. J Mol Biol 2013 0.83
70 Cadmium-induced proteome remodeling regulated by Spc1/Sty1 and Zip1 in fission yeast. Toxicol Sci 2012 0.83
71 Protein interactions among Fe65, the low-density lipoprotein receptor-related protein, and the amyloid precursor protein. Biochemistry 2011 0.83
72 Feedback inhibition by thiols outranks glutathione depletion: a luciferase-based screen reveals glutathione-deficient γ-ECS and glutathione synthetase mutants impaired in cadmium-induced sulfate assimilation. Plant J 2012 0.82
73 Dynamics of the fragment of thrombomodulin containing the fourth and fifth epidermal growth factor-like domains correlate with function. Biochemistry 2005 0.80
74 LRR domain folding: just put a cap on it! Structure 2008 0.79
75 How the ankyrin and SOCS box protein, ASB9, binds to creatine kinase. Biochemistry 2015 0.78
76 Application of amide proton exchange mass spectrometry for the study of protein-protein interactions. Curr Protoc Protein Sci 2005 0.78
77 Autoantibodies in canine masticatory muscle myositis recognize a novel myosin binding protein-C family member. J Immunol 2007 0.77
78 Observation of solvent penetration during cold denaturation of E. coli phosphofructokinase-2. Biophys J 2013 0.77
79 Trypsinogen activation as observed in accelerated molecular dynamics simulations. Protein Sci 2014 0.77
80 A peptide with a ProGln C terminus in the human saliva peptidome exerts bactericidal activity against Propionibacterium acnes. Antimicrob Agents Chemother 2008 0.75
81 Resolving the NFκB hetero-dimer binding paradox: Strain and frustration guide the binding of dimeric transcription factors. J Am Chem Soc 2017 0.75