Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Localizing frustration in native proteins and protein assemblies.
|
Proc Natl Acad Sci U S A
|
2007
|
2.33
|
2
|
Biophysical characterization of the free IkappaBalpha ankyrin repeat domain in solution.
|
Protein Sci
|
2004
|
1.89
|
3
|
Regions of IkappaBalpha that are critical for its inhibition of NF-kappaB.DNA interaction fold upon binding to NF-kappaB.
|
Proc Natl Acad Sci U S A
|
2006
|
1.86
|
4
|
An unexpected twist in viral capsid maturation.
|
Nature
|
2009
|
1.80
|
5
|
Automated extraction of backbone deuteration levels from amide H/2H mass spectrometry experiments.
|
Protein Sci
|
2006
|
1.75
|
6
|
The energy landscape of modular repeat proteins: topology determines folding mechanism in the ankyrin family.
|
J Mol Biol
|
2005
|
1.60
|
7
|
Thermodynamics reveal that helix four in the NLS of NF-kappaB p65 anchors IkappaBalpha, forming a very stable complex.
|
J Mol Biol
|
2006
|
1.59
|
8
|
Stabilizing IkappaBalpha by "consensus" design.
|
J Mol Biol
|
2006
|
1.53
|
9
|
Transfer of flexibility between ankyrin repeats in IkappaB* upon formation of the NF-kappaB complex.
|
J Mol Biol
|
2008
|
1.44
|
10
|
Kinetic enhancement of NF-kappaBxDNA dissociation by IkappaBalpha.
|
Proc Natl Acad Sci U S A
|
2009
|
1.39
|
11
|
On the role of frustration in the energy landscapes of allosteric proteins.
|
Proc Natl Acad Sci U S A
|
2011
|
1.39
|
12
|
Identification of high levels of phytochelatins, glutathione and cadmium in the phloem sap of Brassica napus. A role for thiol-peptides in the long-distance transport of cadmium and the effect of cadmium on iron translocation.
|
Plant J
|
2008
|
1.38
|
13
|
Amide H/2H exchange reveals communication between the cAMP and catalytic subunit-binding sites in the R(I)alpha subunit of protein kinase A.
|
J Mol Biol
|
2002
|
1.36
|
14
|
Pre-folding IkappaBalpha alters control of NF-kappaB signaling.
|
J Mol Biol
|
2008
|
1.35
|
15
|
Epitope mapping of a monoclonal antibody against human thrombin by H/D-exchange mass spectrometry reveals selection of a diverse sequence in a highly conserved protein.
|
Protein Sci
|
2002
|
1.35
|
16
|
Allosteric networks in thrombin distinguish procoagulant vs. anticoagulant activities.
|
Proc Natl Acad Sci U S A
|
2012
|
1.33
|
17
|
Folding landscapes of ankyrin repeat proteins: experiments meet theory.
|
Curr Opin Struct Biol
|
2008
|
1.31
|
18
|
Molecular mechanisms of system control of NF-kappaB signaling by IkappaBalpha.
|
Biochemistry
|
2010
|
1.25
|
19
|
The energy landscapes of repeat-containing proteins: topology, cooperativity, and the folding funnels of one-dimensional architectures.
|
PLoS Comput Biol
|
2008
|
1.25
|
20
|
An improved grafting technique for mature Arabidopsis plants demonstrates long-distance shoot-to-root transport of phytochelatins in Arabidopsis.
|
Plant Physiol
|
2006
|
1.21
|
21
|
Ligand-induced conformational changes in the acetylcholine-binding protein analyzed by hydrogen-deuterium exchange mass spectrometry.
|
J Biol Chem
|
2006
|
1.20
|
22
|
Enhanced conformational space sampling improves the prediction of chemical shifts in proteins.
|
J Am Chem Soc
|
2010
|
1.18
|
23
|
The IkappaBalpha/NF-kappaB complex has two hot spots, one at either end of the interface.
|
Protein Sci
|
2008
|
1.15
|
24
|
Solvent accessibility of protein surfaces by amide H/2H exchange MALDI-TOF mass spectrometry.
|
J Am Soc Mass Spectrom
|
2006
|
1.15
|
25
|
Functional dynamics of the folded ankyrin repeats of I kappa B alpha revealed by nuclear magnetic resonance.
|
Biochemistry
|
2009
|
1.14
|
26
|
Identification of the protein kinase A regulatory RIalpha-catalytic subunit interface by amide H/2H exchange and protein docking.
|
Proc Natl Acad Sci U S A
|
2003
|
1.12
|
27
|
Two apolipoprotein E mimetic peptides, ApoE(130-149) and ApoE(141-155)2, bind to LRP1.
|
Biochemistry
|
2004
|
1.11
|
28
|
Interactions of the NPXY microdomains of the low density lipoprotein receptor-related protein 1.
|
Proteomics
|
2009
|
1.07
|
29
|
Visualization of the nanospring dynamics of the IkappaBalpha ankyrin repeat domain in real time.
|
Proc Natl Acad Sci U S A
|
2011
|
1.06
|
30
|
Solvent exposed non-contacting amino acids play a critical role in NF-kappaB/IkappaBalpha complex formation.
|
J Mol Biol
|
2002
|
1.05
|
31
|
Thrombomodulin tightens the thrombin active site loops to promote protein C activation.
|
Biochemistry
|
2005
|
1.04
|
32
|
Allosteric changes in solvent accessibility observed in thrombin upon active site occupation.
|
Biochemistry
|
2004
|
1.04
|
33
|
Critical salt bridges guide capsid assembly, stability, and maturation behavior in bacteriophage HK97.
|
Mol Cell Proteomics
|
2010
|
1.01
|
34
|
Direct observation of a transient ternary complex during IκBα-mediated dissociation of NF-κB from DNA.
|
Proc Natl Acad Sci U S A
|
2013
|
0.98
|
35
|
The dynamic structure of thrombin in solution.
|
Biophys J
|
2012
|
0.98
|
36
|
Induced fit, folding, and recognition of the NF-kappaB-nuclear localization signals by IkappaBalpha and IkappaBbeta.
|
J Mol Biol
|
2006
|
0.97
|
37
|
Direct analysis of the kinetic profiles of organophosphate-acetylcholinesterase adducts by MALDI-TOF mass spectrometry.
|
Biochemistry
|
2003
|
0.96
|
38
|
ARS5 is a component of the 26S proteasome complex, and negatively regulates thiol biosynthesis and arsenic tolerance in Arabidopsis.
|
Plant J
|
2009
|
0.95
|
39
|
Structure of the minimal interface between ApoE and LRP.
|
J Mol Biol
|
2010
|
0.95
|
40
|
HK97 maturation studied by crystallography and H/2H exchange reveals the structural basis for exothermic particle transitions.
|
J Mol Biol
|
2010
|
0.94
|
41
|
The plastic landscape of repeat proteins.
|
Proc Natl Acad Sci U S A
|
2007
|
0.94
|
42
|
Structural and functional consequences of tyrosine phosphorylation in the LRP1 cytoplasmic domain.
|
J Biol Chem
|
2008
|
0.93
|
43
|
Decoding of lipoprotein-receptor interactions: properties of ligand binding modules governing interactions with apolipoprotein E.
|
Biochemistry
|
2010
|
0.92
|
44
|
Methods for studying transmembrane peptides in bicelles: consequences of hydrophobic mismatch and peptide sequence.
|
J Magn Reson
|
2002
|
0.92
|
45
|
Prediction of native-state hydrogen exchange from perfectly funneled energy landscapes.
|
J Am Chem Soc
|
2011
|
0.92
|
46
|
Two different proteins that compete for binding to thrombin have opposite kinetic and thermodynamic profiles.
|
Protein Sci
|
2004
|
0.91
|
47
|
Discrete kinetic models from funneled energy landscape simulations.
|
PLoS One
|
2012
|
0.91
|
48
|
Folding kinetics of the cooperatively folded subdomain of the IκBα ankyrin repeat domain.
|
J Mol Biol
|
2011
|
0.90
|
49
|
The RelA nuclear localization signal folds upon binding to IκBα.
|
J Mol Biol
|
2010
|
0.89
|
50
|
Thermodynamic compensation upon binding to exosite 1 and the active site of thrombin.
|
Biochemistry
|
2011
|
0.88
|
51
|
R-subunit isoform specificity in protein kinase A: distinct features of protein interfaces in PKA types I and II by amide H/2H exchange mass spectrometry.
|
J Mol Biol
|
2007
|
0.88
|
52
|
NMR structures reveal how oxidation inactivates thrombomodulin.
|
Biochemistry
|
2003
|
0.87
|
53
|
Correlated motions and residual frustration in thrombin.
|
J Phys Chem B
|
2013
|
0.87
|
54
|
The structure, dynamics, and binding of the LA45 module pair of the low-density lipoprotein receptor suggest an important role for LA4 in ligand release.
|
Biochemistry
|
2011
|
0.87
|
55
|
Predicted disorder-to-order transition mutations in IκBα disrupt function.
|
Phys Chem Chem Phys
|
2014
|
0.87
|
56
|
Detection of a ternary complex of NF-kappaB and IkappaBalpha with DNA provides insights into how IkappaBalpha removes NF-kappaB from transcription sites.
|
Proc Natl Acad Sci U S A
|
2011
|
0.86
|
57
|
Expanding proteome coverage with orthogonal-specificity α-lytic proteases.
|
Mol Cell Proteomics
|
2014
|
0.86
|
58
|
Role of disorder in IκB-NFκB interaction.
|
IUBMB Life
|
2012
|
0.86
|
59
|
Amide H/2H exchange reveals a mechanism of thrombin activation.
|
Biochemistry
|
2006
|
0.86
|
60
|
Hydrogen-exchange mass spectrometry for the study of intrinsic disorder in proteins.
|
Biochim Biophys Acta
|
2012
|
0.86
|
61
|
All three LDL receptor homology regions of the LDL receptor-related protein bind multiple ligands.
|
Biochemistry
|
2003
|
0.86
|
62
|
Identification of an arsenic tolerant double mutant with a thiol-mediated component and increased arsenic tolerance in phyA mutants.
|
Plant J
|
2007
|
0.86
|
63
|
Consequences of IkappaB alpha hydroxylation by the factor inhibiting HIF (FIH).
|
FEBS Lett
|
2010
|
0.85
|
64
|
Measurement of solvent accessibility at protein-protein interfaces.
|
Methods Mol Biol
|
2005
|
0.85
|
65
|
Structural and functional consequences of methionine oxidation in thrombomodulin.
|
Biochim Biophys Acta
|
2005
|
0.84
|
66
|
Mutations in the fourth EGF-like domain affect thrombomodulin-induced changes in the active site of thrombin.
|
Biochemistry
|
2008
|
0.84
|
67
|
Long-range effects and functional consequences of stabilizing mutations in the ankyrin repeat domain of IκBα.
|
J Mol Biol
|
2012
|
0.83
|
68
|
Rapid mass spectrometric analysis of 15N-Leu incorporation fidelity during preparation of specifically labeled NMR samples.
|
Protein Sci
|
2008
|
0.83
|
69
|
Single-molecule FRET reveals the native-state dynamics of the IκBα ankyrin repeat domain.
|
J Mol Biol
|
2013
|
0.83
|
70
|
Cadmium-induced proteome remodeling regulated by Spc1/Sty1 and Zip1 in fission yeast.
|
Toxicol Sci
|
2012
|
0.83
|
71
|
Protein interactions among Fe65, the low-density lipoprotein receptor-related protein, and the amyloid precursor protein.
|
Biochemistry
|
2011
|
0.83
|
72
|
Feedback inhibition by thiols outranks glutathione depletion: a luciferase-based screen reveals glutathione-deficient γ-ECS and glutathione synthetase mutants impaired in cadmium-induced sulfate assimilation.
|
Plant J
|
2012
|
0.82
|
73
|
Dynamics of the fragment of thrombomodulin containing the fourth and fifth epidermal growth factor-like domains correlate with function.
|
Biochemistry
|
2005
|
0.80
|
74
|
LRR domain folding: just put a cap on it!
|
Structure
|
2008
|
0.79
|
75
|
How the ankyrin and SOCS box protein, ASB9, binds to creatine kinase.
|
Biochemistry
|
2015
|
0.78
|
76
|
Application of amide proton exchange mass spectrometry for the study of protein-protein interactions.
|
Curr Protoc Protein Sci
|
2005
|
0.78
|
77
|
Autoantibodies in canine masticatory muscle myositis recognize a novel myosin binding protein-C family member.
|
J Immunol
|
2007
|
0.77
|
78
|
Observation of solvent penetration during cold denaturation of E. coli phosphofructokinase-2.
|
Biophys J
|
2013
|
0.77
|
79
|
Trypsinogen activation as observed in accelerated molecular dynamics simulations.
|
Protein Sci
|
2014
|
0.77
|
80
|
A peptide with a ProGln C terminus in the human saliva peptidome exerts bactericidal activity against Propionibacterium acnes.
|
Antimicrob Agents Chemother
|
2008
|
0.75
|
81
|
Resolving the NFκB hetero-dimer binding paradox: Strain and frustration guide the binding of dimeric transcription factors.
|
J Am Chem Soc
|
2017
|
0.75
|