Alfons Verbruggen

Author PubWeight™ 59.55‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A dual-targeting anticancer approach: soil and seed principle. Radiology 2011 1.21
2 Molecular imaging of cell death. Methods 2009 1.17
3 Molecular imaging of alpha v beta3 integrin expression in atherosclerotic plaques with a mimetic of RGD peptide grafted to Gd-DTPA. Cardiovasc Res 2008 1.17
4 Non-invasive detection and quantification of acute myocardial infarction in rabbits using mono-[123I]iodohypericin microSPECT. Eur Heart J 2007 1.07
5 Abeta amyloid deposition in the language system and how the brain responds. Brain 2007 1.05
6 Necrosis avidity of (99m)Tc(CO)3-labeled pamoic acid derivatives: synthesis and preliminary biological evaluation in animal models of necrosis. Bioconjug Chem 2007 1.01
7 Rapid clearance of the circulating metastatic factor autotaxin by the scavenger receptors of liver sinusoidal endothelial cells. Cancer Lett 2009 1.00
8 A review on various targeted anticancer therapies. Target Oncol 2012 0.98
9 Necrosis avid contrast agents: functional similarity versus structural diversity. Invest Radiol 2005 0.96
10 Apoptosis imaging to monitor cancer therapy: the road to fast treatment evaluation? Curr Pharm Biotechnol 2012 0.95
11 Exploring theranostic potentials of radioiodinated hypericin in rodent necrosis models. Theranostics 2012 0.95
12 Preclinical evaluation of 18F-JNJ41510417 as a radioligand for PET imaging of phosphodiesterase-10A in the brain. J Nucl Med 2010 0.95
13 Site-specific 68Ga-labeled Annexin A5 as a PET imaging agent for apoptosis. Nucl Med Biol 2010 0.94
14 Radiolabeled iodohypericin as tumor necrosis avid tracer: diagnostic and therapeutic potential. Int J Cancer 2012 0.93
15 Feasibility and availability of ⁶⁸Ga-labelled peptides. Eur J Nucl Med Mol Imaging 2012 0.93
16 Evaluation of tumor affinity of mono-[(123)I]iodohypericin and mono-[(123)I]iodoprotohypericin in a mouse model with a RIF-1 tumor. Contrast Media Mol Imaging 2007 0.93
17 Dual-tracer dopamine transporter and perfusion SPECT in differential diagnosis of parkinsonism using template-based discriminant analysis. J Nucl Med 2006 0.91
18 Site-specific labeling of 'second generation' annexin V with 99mTc(CO)3 for improved imaging of apoptosis in vivo. Bioorg Med Chem 2010 0.91
19 Sequential systemic administrations of combretastatin A4 Phosphate and radioiodinated hypericin exert synergistic targeted theranostic effects with prolonged survival on SCID mice carrying bifocal tumor xenografts. Theranostics 2013 0.90
20 The value of (18)FDG-PET for the detection of infected hip prosthesis. Eur J Nucl Med Mol Imaging 2003 0.89
21 Developing new molecular imaging probes for PET. Methods 2009 0.89
22 Whole-body biodistribution and radiation dosimetry of the cannabinoid type 2 receptor ligand [11C]-NE40 in healthy subjects. Mol Imaging Biol 2013 0.88
23 Synthesis and evaluation of a (99m)Tc-MAMA-propyl-thymidine complex as a potential probe for in vivo visualization of tumor cell proliferation with SPECT. Nucl Med Biol 2007 0.87
24 A PET brain reporter gene system based on type 2 cannabinoid receptors. J Nucl Med 2011 0.87
25 Diverse responses to vascular disrupting agent combretastatin a4 phosphate: a comparative study in rats with hepatic and subcutaneous tumor allografts using MRI biomarkers, microangiography, and histopathology. Transl Oncol 2013 0.86
26 Synthesis and evaluation of 18F- and 11C-labeled phenyl-galactopyranosides as potential probes for in vivo visualization of LacZ gene expression using positron emission tomography. Bioconjug Chem 2008 0.86
27 Continuing pursuit for ideal systemic anticancer radiotherapeutics. Invest New Drugs 2011 0.86
28 The impact of aggregation on the biodistribution of hypericin. Int J Oncol 2006 0.85
29 Small Molecule Sequential Dual-Targeting Theragnostic Strategy (SMSDTTS): from Preclinical Experiments towards Possible Clinical Anticancer Applications. J Cancer 2013 0.85
30 Optimal buffer choice of the radiosynthesis of (68)Ga-Dotatoc for clinical application. Nucl Med Commun 2010 0.85
31 Synthesis and preliminary evaluation of mono-[123I]iodohypericin monocarboxylic acid as a necrosis avid imaging agent. Bioorg Med Chem Lett 2007 0.83
32 Intracoronary beta-radiation of de novo coronary lesions using a (186)Re liquid-filled balloon system: six-month results from a clinical feasibility study. Catheter Cardiovasc Interv 2002 0.83
33 A safety study on single intravenous dose of tetrachloro-diphenyl glycoluril [iodogen] dissolved in dimethyl sulphoxide (DMSO). Xenobiotica 2013 0.83
34 Magnetic resonance imaging after radiofrequency ablation in a rodent model of liver tumor: tissue characterization using a novel necrosis-avid contrast agent. Eur Radiol 2006 0.82
35 A single-dose toxicity study on non-radioactive iodinated hypericin for a targeted anticancer therapy in mice. Acta Pharmacol Sin 2012 0.82
36 Improved synthesis and metabolic stability analysis of the dopamine transporter ligand [(18)F]FECT. Nucl Med Biol 2007 0.82
37 Preliminary in vivo evaluation of a novel 99mTc-labeled HYNIC-cys-annexin A5 as an apoptosis imaging agent. Bioorg Med Chem Lett 2008 0.82
38 Synthesis, characterization, and pharmacokinetic evaluation of a potential MRI contrast agent containing two paramagnetic centers with albumin binding affinity. Chemistry 2005 0.82
39 Individualized dosimetry-based activity reduction of ⁹⁰Y-DOTATOC prevents severe and rapid kidney function deterioration from peptide receptor radionuclide therapy. Eur J Nucl Med Mol Imaging 2014 0.82
40 Influence of time delay on the estimated lung shunt fraction on 99mTc-labeled MAA scintigraphy for 90Y microsphere treatment planning. Clin Nucl Med 2013 0.81
41 Synthesis and biological evaluation of [¹¹C]SB366791: a new PET-radioligand for in vivo imaging of the TRPV1 receptor. Nucl Med Biol 2012 0.81
42 Synthesis and biological evaluation of (11)C-labeled beta-galactosyl triazoles as potential PET tracers for in vivo LacZ reporter gene imaging. Bioorg Med Chem 2009 0.80
43 Morphologic and functional changes in the unilateral 6-hydroxydopamine lesion rat model for Parkinson's disease discerned with microSPECT and quantitative MRI. MAGMA 2010 0.80
44 Identity confirmation of 99mTc-MAG3, 99mTc-sestamibi and 99mTc-ECD using radio-LC-MS. J Pharm Biomed Anal 2003 0.80
45 Development of a conjugate of (99m)Tc-EC with aminomethylenediphosphonate in the search for a bone tracer with fast clearance from soft tissue. Bioconjug Chem 2002 0.79
46 Significant impact of transient deterioration of renal function on dosimetry in PRRT. Ann Nucl Med 2012 0.79
47 Optimization of the preparation of 99mTc-labeled Hynic-derivatized Annexin V for human use. Nucl Med Biol 2003 0.79
48 Synthesis and evaluation of 18F-labeled 2-phenylbenzothiazoles as positron emission tomography imaging agents for amyloid plaques in Alzheimer's disease. J Med Chem 2009 0.79
49 Improved clearance of radioiodinated hypericin as a targeted anticancer agent by using a duodenal drainage catheter in rats. Exp Biol Med (Maywood) 2013 0.78
50 Radioiodinated hypericin: its biodistribution, necrosis avidity and therapeutic efficacy are influenced by formulation. Pharm Res 2013 0.78
51 Comparative study of iodine-123-labeled hypericin and (99m)Tc-labeled hexakis [2-methoxy isobutyl isonitrile] in a rabbit model of myocardial infarction. J Cardiovasc Pharmacol 2013 0.78
52 Development and evaluation of a 68Ga labeled pamoic acid derivative for in vivo visualization of necrosis using positron emission tomography. Bioorg Med Chem 2010 0.78
53 Preliminary validation of varicella zoster virus thymidine kinase as a novel reporter gene for PET. Nucl Med Biol 2012 0.78
54 Ga-68 DOTATOC PET/CT changed the therapeutic course of a patient with the sudden onset of vision problems. Clin Nucl Med 2009 0.78
55 Preclinical imaging of therapy response using metabolic and apoptosis molecular imaging. Mol Imaging Biol 2011 0.77
56 Radioiodinated phenylalkyl malonic acid derivatives as pH-sensitive SPECT tracers. PLoS One 2012 0.77
57 Targetability and biodistribution of radioiodinated hypericin: comparison between microdosing and carrier-added preparations. Anticancer Agents Med Chem 2014 0.77
58 The presence of ethanol in radiopharmaceutical injections. J Nucl Med 2008 0.77
59 Radiolabeling and preliminary biological evaluation of a (99m)Tc(CO)(3) labeled 3,3'-(benzylidene)-bis-(1H-indole-2-carbohydrazide) derivative as a potential SPECT tracer for in vivo visualization of necrosis. Bioorg Med Chem Lett 2010 0.77
60 Biodistribution and pharmacokinetics of PEG-10kDa-cholecystokinin-10 in rats after different routes of administration. Curr Drug Deliv 2010 0.77
61 PET radioligands for in vivo visualization of neuroinflammation. Curr Pharm Des 2014 0.76
62 The effect of a methyl or 2-fluoroethyl substituent at the N-3 position of thymidine, 3'-fluoro-3'-deoxythymidine and 1-beta-D-arabinosylthymine on their antiviral and cytostatic activity in cell culture. Antivir Chem Chemother 2006 0.76
63 Accumulation and photocytotoxicity of hypericin and analogs in two- and three-dimensional cultures of transitional cell carcinoma cells. Photochem Photobiol 2003 0.76
64 Exploring multifunctional features of necrosis avid contrast agents. Acad Radiol 2002 0.76
65 Necrosis-avid contrast agents: introducing nonporphyrin species. Acad Radiol 2002 0.76
66 Altered biodistribution of somatostatin analogues after first cycle of Peptide receptor radionuclide therapy. J Clin Oncol 2011 0.75
67 Sodium cholate, a solubilizing agent for the necrosis avid radioiodinated hypericin in rabbits with acute myocardial infarction. Drug Deliv 2014 0.75
68 Validation of octanoate breath test for measuring gastric emptying in rats. J Neurogastroenterol Motil 2013 0.75
69 Study on the microbial safety of an infusion set for contrast-enhanced imaging. Invest Radiol 2012 0.75
70 New transient receptor potential vanilloid subfamily member 1 positron emission tomography radioligands: synthesis, radiolabeling, and preclinical evaluation. ACS Chem Neurosci 2013 0.75
71 Characterisation and biodistribution of two neutral 99mTc(CO)3 complexes with a tridentate ligand. Bioorg Med Chem Lett 2005 0.75
72 Dynamic 68Ga-DOTATOC PET/CT and static image in NET patients. Correlation of parameters during PRRT. Nuklearmedizin 2016 0.75
73 Synthesis and evaluation of three 18F-labeled aminophenylbenzothiazoles as amyloid imaging agents. J Med Chem 2009 0.75
74 Pretargeted PET imaging using a bioorthogonal 18F-labeled trans-cyclooctene in an ovarian carcinoma model. Bioconjug Chem 2017 0.75
75 Synthetic strategies for radioligands for in vivo imaging of brain cannabinoid type-1 receptors. J Labelled Comp Radiopharm 2013 0.75
76 Synthesis and biological evaluation of 68Ga labeled bis-DOTA-3,3'-(benzylidene)-bis-(1H-indole-2-carbohydrazide) as a PET tracer for in vivo visualization of necrosis. Bioorg Med Chem Lett 2013 0.75
77 99mTc-tricarbonyl labeled agents for cell labeling: development, biodistribution in normal mice and preliminary in vitro evaluation. Bioorg Med Chem 2009 0.75