Published in Infect Immun on April 01, 2006
Anaplasma phagocytophilum and Ehrlichia chaffeensis: subversive manipulators of host cells. Nat Rev Microbiol (2010) 1.57
Whole genome transcription profiling of Anaplasma phagocytophilum in human and tick host cells by tiling array analysis. BMC Genomics (2008) 1.45
Mechanisms of obligatory intracellular infection with Anaplasma phagocytophilum. Clin Microbiol Rev (2011) 1.44
Structure of the expression site reveals global diversity in MSP2 (P44) variants in Anaplasma phagocytophilum. Infect Immun (2006) 1.40
Global proteomic analysis of two tick-borne emerging zoonotic agents: anaplasma phagocytophilum and ehrlichia chaffeensis. Front Microbiol (2011) 1.18
Identification of novel surface proteins of Anaplasma phagocytophilum by affinity purification and proteomics. J Bacteriol (2007) 1.13
Porin activity of Anaplasma phagocytophilum outer membrane fraction and purified P44. J Bacteriol (2006) 1.08
Anaplasma phagocytophilum MSP2(P44)-18 predominates and is modified into multiple isoforms in human myeloid cells. Infect Immun (2008) 1.02
Anaplasma phagocytophilum p44 mRNA expression is differentially regulated in mammalian and tick host cells: involvement of the DNA binding protein ApxR. J Bacteriol (2007) 1.00
Differential expression and glycosylation of anaplasma phagocytophilum major surface protein 2 paralogs during cultivation in sialyl Lewis x-deficient host cells. Infect Immun (2009) 0.90
Antigen diversity in the parasitic bacterium Anaplasma phagocytophilum arises from selectively-represented, spatially clustered functional pseudogenes. PLoS One (2009) 0.90
Comparative genomics of first available bovine Anaplasma phagocytophilum genome obtained with targeted sequence capture. BMC Genomics (2014) 0.87
Evolution of antigen variation in the tick-borne pathogen Anaplasma phagocytophilum. Mol Biol Evol (2011) 0.84
Antigen variability in Anaplasma phagocytophilum during chronic infection of a reservoir host. Microbiology (2012) 0.84
Mini-review: Strategies for Variation and Evolution of Bacterial Antigens. Comput Struct Biotechnol J (2015) 0.79
Cloning of the major outer membrane protein expression locus in Anaplasma platys and seroreactivity of a species-specific antigen. J Bacteriol (2011) 0.76
Analysis of complete genome sequence and major surface antigens of Neorickettsia helminthoeca, causative agent of salmon poisoning disease. Microb Biotechnol (2017) 0.75
Molecular characterization of Msp2/P44 of Anaplasma phagocytophilum isolated from infected patients and Haemaphysalis longicornis in Laizhou Bay, Shandong Province, China. PLoS One (2013) 0.75
Identification of a granulocytotropic Ehrlichia species as the etiologic agent of human disease. J Clin Microbiol (1994) 9.97
Biochemistry of homologous recombination in Escherichia coli. Microbiol Rev (1994) 9.93
Genetic analysis of the recF pathway to genetic recombination in Escherichia coli K12: isolation and characterization of mutants. J Mol Biol (1973) 7.34
Genetic recombination in Escherichia coli: the role of exonuclease I. Proc Natl Acad Sci U S A (1971) 6.74
Differential timing and control of noncrossover and crossover recombination during meiosis. Cell (2001) 5.57
Direct cultivation of the causative agent of human granulocytic ehrlichiosis. N Engl J Med (1996) 5.35
Clinical and laboratory characteristics of human granulocytic ehrlichiosis. JAMA (1996) 4.88
Compilation of E. coli mRNA promoter sequences. Nucleic Acids Res (1993) 4.84
Mating-type gene switching in Saccharomyces cerevisiae. Annu Rev Genet (1998) 4.08
Identification and genetic analysis of sbcC mutations in commonly used recBC sbcB strains of Escherichia coli K-12. J Bacteriol (1985) 3.43
Genetic analysis of the recJ gene of Escherichia coli K-12. J Bacteriol (1984) 2.90
Multiple p44 genes encoding major outer membrane proteins are expressed in the human granulocytic ehrlichiosis agent. J Biol Chem (1999) 2.68
Antigenic variation in vector-borne pathogens. Emerg Infect Dis (2000) 2.39
Differential roles of homologous recombination pathways in Neisseria gonorrhoeae pilin antigenic variation, DNA transformation and DNA repair. Mol Microbiol (1998) 2.24
Antigenic variation of Anaplasma marginale by expression of MSP2 mosaics. Infect Immun (2000) 2.15
Antigenic variation of Anaplasma marginale msp2 occurs by combinatorial gene conversion. Mol Microbiol (2002) 2.08
Efficient use of a small genome to generate antigenic diversity in tick-borne ehrlichial pathogens. Proc Natl Acad Sci U S A (2001) 2.02
Molecular models accounting for the gene conversion reactions mediating gonococcal pilin antigenic variation. Mol Microbiol (2000) 1.70
Expression of multiple outer membrane protein sequence variants from a single genomic locus of Anaplasma phagocytophilum. Infect Immun (2003) 1.70
Mechanisms for gene conversion and homologous recombination: the double-strand break repair model and the successive half crossing-over model. Adv Biophys (1992) 1.64
Characterization of monoclonal antibodies to the 44-kilodalton major outer membrane protein of the human granulocytic ehrlichiosis agent. J Clin Microbiol (1998) 1.61
Gene conversion and concerted evolution in bacterial genomes. FEMS Microbiol Rev (2005) 1.57
Structural basis for segmental gene conversion in generation of Anaplasma marginale outer membrane protein variants. Mol Microbiol (2005) 1.50
Analysis of sequences and loci of p44 homologs expressed by Anaplasma phagocytophila in acutely infected patients. J Clin Microbiol (2002) 1.45
Transcript heterogeneity of the p44 multigene family in a human granulocytic ehrlichiosis agent transmitted by ticks. Infect Immun (2002) 1.43
Nonconservative recombination in Escherichia coli. Proc Natl Acad Sci U S A (1992) 1.32
A novel family of regulated helicases/nucleases from Gram-positive bacteria: insights into the initiation of DNA recombination. Mol Microbiol (2002) 1.31
Mechanisms of variable p44 expression by Anaplasma phagocytophilum. Infect Immun (2003) 1.28
Expression of interleukin-1beta, tumor necrosis factor alpha, and interleukin-6 in human peripheral blood leukocytes exposed to human granulocytic ehrlichiosis agent or recombinant major surface protein P44. Infect Immun (2000) 1.23
Sequence analysis of p44 homologs expressed by Anaplasma phagocytophilum in infected ticks feeding on naive hosts and in mice infected by tick attachment. Infect Immun (2004) 1.22
Rapid sequential changeover of expressed p44 genes during the acute phase of Anaplasma phagocytophilum infection in horses. Infect Immun (2004) 1.21
The size and position of heterologous insertions in a silent locus differentially affect pilin recombination in Neisseria gonorrhoeae. Mol Microbiol (1996) 1.15
Establishment of cloned Anaplasma phagocytophilum and analysis of p44 gene conversion within an infected horse and infected SCID mice. Infect Immun (2005) 1.12
Dependence of frequency of homologous recombination on the homology length. Genetics (1995) 1.10
Gene conversion in the Escherichia coli RecF pathway: a successive half crossing-over model. Mol Gen Genet (1992) 1.09
Factors affecting PCR-mediated recombination. Environ Microbiol (2002) 1.06
Two monoclonal antibodies with defined epitopes of P44 major surface proteins neutralize Anaplasma phagocytophilum by distinct mechanisms. Infect Immun (2006) 1.01
The recombination genes addAB are not restricted to gram-positive bacteria: genetic analysis of the recombination initiation enzymes RecF and AddAB in Rhizobium etli. J Bacteriol (2004) 0.96
Mechanisms to create a safe haven by members of the family Anaplasmataceae. Ann N Y Acad Sci (2003) 0.95
Activation of a p44 pseudogene in Anaplasma phagocytophila by bacterial RNA splicing: a novel mechanism for post-transcriptional regulation of a multigene family encoding immunodominant major outer membrane proteins. Mol Microbiol (2002) 0.95
National surveillance for the human ehrlichioses in the United States, 1997-2001, and proposed methods for evaluation of data quality. Ann N Y Acad Sci (2003) 0.89
Ehrlichial strategy for survival and proliferation in leukocytes. Subcell Biochem (2000) 0.83
Comparative genomics of emerging human ehrlichiosis agents. PLoS Genet (2006) 4.23
Ehrlichia chaffeensis and Anaplasma phagocytophilum lack genes for lipid A biosynthesis and incorporate cholesterol for their survival. Infect Immun (2003) 2.37
Ultrastructure and phylogenetic analysis of 'Candidatus Neoehrlichia mikurensis' in the family Anaplasmataceae, isolated from wild rats and found in Ixodes ovatus ticks. Int J Syst Evol Microbiol (2004) 2.35
Anaplasma phagocytophilum AnkA secreted by type IV secretion system is tyrosine phosphorylated by Abl-1 to facilitate infection. Cell Microbiol (2007) 2.09
Airborne particulate matter selectively activates endoplasmic reticulum stress response in the lung and liver tissues. Am J Physiol Cell Physiol (2010) 2.06
Characterization and transcriptional analysis of gene clusters for a type IV secretion machinery in human granulocytic and monocytic ehrlichiosis agents. Infect Immun (2002) 1.61
Revision of haemotrophic Mycoplasma species names. Int J Syst Evol Microbiol (2002) 1.57
Analysis of sequences and loci of p44 homologs expressed by Anaplasma phagocytophila in acutely infected patients. J Clin Microbiol (2002) 1.45
Human infection with Ehrlichia canis accompanied by clinical signs in Venezuela. Ann N Y Acad Sci (2006) 1.43
Transcript heterogeneity of the p44 multigene family in a human granulocytic ehrlichiosis agent transmitted by ticks. Infect Immun (2002) 1.43
Novel genetic variants of Anaplasma phagocytophilum, Anaplasma bovis, Anaplasma centrale, and a novel Ehrlichia sp. in wild deer and ticks on two major islands in Japan. Appl Environ Microbiol (2006) 1.31
Autophagosomes induced by a bacterial Beclin 1 binding protein facilitate obligatory intracellular infection. Proc Natl Acad Sci U S A (2012) 1.28
Mechanisms of variable p44 expression by Anaplasma phagocytophilum. Infect Immun (2003) 1.28
Exposure to ambient particulate matter induces a NASH-like phenotype and impairs hepatic glucose metabolism in an animal model. J Hepatol (2012) 1.28
Surface-exposed proteins of Ehrlichia chaffeensis. Infect Immun (2007) 1.26
Transstadial and intrastadial experimental transmission of Ehrlichia canis by male Rhipicephalus sanguineus. Vet Parasitol (2005) 1.24
Anaplasma phagocytophilum Ats-1 is imported into host cell mitochondria and interferes with apoptosis induction. PLoS Pathog (2010) 1.23
Sequence analysis of p44 homologs expressed by Anaplasma phagocytophilum in infected ticks feeding on naive hosts and in mice infected by tick attachment. Infect Immun (2004) 1.22
Subversion of cellular autophagy by Anaplasma phagocytophilum. Cell Microbiol (2007) 1.22
Rapid sequential changeover of expressed p44 genes during the acute phase of Anaplasma phagocytophilum infection in horses. Infect Immun (2004) 1.21
The omp-1 major outer membrane multigene family of Ehrlichia chaffeensis is differentially expressed in canine and tick hosts. Infect Immun (2002) 1.21
Neorickettsia risticii is vertically transmitted in the trematode Acanthatrium oregonense and horizontally transmitted to bats. Environ Microbiol (2005) 1.19
Global proteomic analysis of two tick-borne emerging zoonotic agents: anaplasma phagocytophilum and ehrlichia chaffeensis. Front Microbiol (2011) 1.18
Anaplasma phagocytophilum inhibits human neutrophil apoptosis via upregulation of bfl-1, maintenance of mitochondrial membrane potential and prevention of caspase 3 activation. Cell Microbiol (2005) 1.18
Intra-leukocyte expression of two-component systems in Ehrlichia chaffeensis and Anaplasma phagocytophilum and effects of the histidine kinase inhibitor closantel. Cell Microbiol (2006) 1.18
Differential expression of VirB9 and VirB6 during the life cycle of Anaplasma phagocytophilum in human leucocytes is associated with differential binding and avoidance of lysosome pathway. Cell Microbiol (2006) 1.17
Detection of Ehrlichia canis in canine carrier blood and in individual experimentally infected ticks with a p30-based PCR assay. J Clin Microbiol (2002) 1.16
Effects of Anaplasma phagocytophila on NADPH oxidase components in human neutrophils and HL-60 cells. Infect Immun (2002) 1.16
Obligatory intracellular parasitism by Ehrlichia chaffeensis and Anaplasma phagocytophilum involves caveolae and glycosylphosphatidylinositol-anchored proteins. Cell Microbiol (2003) 1.15
Cyclic di-GMP signaling regulates invasion by Ehrlichia chaffeensis of human monocytes. J Bacteriol (2010) 1.13
Identification of novel surface proteins of Anaplasma phagocytophilum by affinity purification and proteomics. J Bacteriol (2007) 1.13
Establishment of cloned Anaplasma phagocytophilum and analysis of p44 gene conversion within an infected horse and infected SCID mice. Infect Immun (2005) 1.12
Anaplasma phagocytophilum delays spontaneous human neutrophil apoptosis by modulation of multiple apoptotic pathways. Cell Microbiol (2006) 1.12
Biochemical activities of three pairs of Ehrlichia chaffeensis two-component regulatory system proteins involved in inhibition of lysosomal fusion. Infect Immun (2006) 1.12
The Anaplasma phagocytophilum PleC histidine kinase and PleD diguanylate cyclase two-component system and role of cyclic Di-GMP in host cell infection. J Bacteriol (2008) 1.09
Porin activity of Anaplasma phagocytophilum outer membrane fraction and purified P44. J Bacteriol (2006) 1.08
Regulation of type IV secretion apparatus genes during Ehrlichia chaffeensis intracellular development by a previously unidentified protein. J Bacteriol (2008) 1.08
Proteomic analysis of and immune responses to Ehrlichia chaffeensis lipoproteins. Infect Immun (2008) 1.07
Ehrlichia chaffeensis downregulates surface Toll-like receptors 2/4, CD14 and transcription factors PU.1 and inhibits lipopolysaccharide activation of NF-kappa B, ERK 1/2 and p38 MAPK in host monocytes. Cell Microbiol (2004) 1.06
Rapid activation of protein tyrosine kinase and phospholipase C-gamma2 and increase in cytosolic free calcium are required by Ehrlichia chaffeensis for internalization and growth in THP-1 cells. Infect Immun (2002) 1.06
Genetic analysis and QTL detection of reproductive period and post-flowering photoperiod responses in soybean. Theor Appl Genet (2011) 1.06
Virulence potential of Ehrlichia chaffeensis strains of distinct genome sequences. Infect Immun (2007) 1.02
Tick acquisition of Ehrlichia canis from dogs treated with doxycycline hyclate. Antimicrob Agents Chemother (2007) 1.02
Insights into the CtrA regulon in development of stress resistance in obligatory intracellular pathogen Ehrlichia chaffeensis. Mol Microbiol (2011) 1.01
Analysis of p51, groESL, and the major antigen P51 in various species of Neorickettsia, an obligatory intracellular bacterium that infects trematodes and mammals. J Clin Microbiol (2004) 1.01
Two monoclonal antibodies with defined epitopes of P44 major surface proteins neutralize Anaplasma phagocytophilum by distinct mechanisms. Infect Immun (2006) 1.01
Anaplasma phagocytophilum p44 mRNA expression is differentially regulated in mammalian and tick host cells: involvement of the DNA binding protein ApxR. J Bacteriol (2007) 1.00
Expression and porin activity of P28 and OMP-1F during intracellular Ehrlichia chaffeensis development. J Bacteriol (2008) 1.00
Analysis of complete genome sequence of Neorickettsia risticii: causative agent of Potomac horse fever. Nucleic Acids Res (2009) 0.99
Ehrlichia ewingii infection delays spontaneous neutrophil apoptosis through stabilization of mitochondria. J Infect Dis (2008) 0.96
Experimental infection of dairy calves with Ehrlichia chaffeensis. J Med Microbiol (2007) 0.95
Proteomic identification of a novel Anaplasma phagocytophilum DNA binding protein that regulates a putative transcription factor. J Bacteriol (2007) 0.95
Activation of a p44 pseudogene in Anaplasma phagocytophila by bacterial RNA splicing: a novel mechanism for post-transcriptional regulation of a multigene family encoding immunodominant major outer membrane proteins. Mol Microbiol (2002) 0.95
Polymorphism and transcription at the p44-1/p44-18 genomic locus in Anaplasma phagocytophilum strains from diverse geographic regions. Infect Immun (2004) 0.95
Anaplasma phagocytophilum has a functional msp2 gene that is distinct from p44. Infect Immun (2004) 0.95
Four VirB6 paralogs and VirB9 are expressed and interact in Ehrlichia chaffeensis-containing vacuoles. J Bacteriol (2008) 0.94
Cholesterol-dependent anaplasma phagocytophilum exploits the low-density lipoprotein uptake pathway. PLoS Pathog (2009) 0.94
Measurement of ER stress response and inflammation in the mouse model of nonalcoholic fatty liver disease. Methods Enzymol (2011) 0.94
Sequence and expression analysis of virB9 of the type IV secretion system of Ehrlichia canis strains in ticks, dogs, and cultured cells. Infect Immun (2003) 0.93
Degradation of p22phox and inhibition of superoxide generation by Ehrlichia chaffeensis in human monocytes. Cell Microbiol (2006) 0.92
Cytokine gene expression by peripheral blood leukocytes in horses experimentally infected with Anaplasma phagocytophila. Clin Diagn Lab Immunol (2002) 0.92
Cytokine gene expression by peripheral blood leukocytes in dogs experimentally infected with a new virulent strain of Ehrlichia canis. Ann N Y Acad Sci (2006) 0.91
Molecular analysis of Neorickettsia risticii in adult aquatic insects in Pennsylvania, in horses infected by ingestion of insects, and isolated in cell culture. J Clin Microbiol (2002) 0.91
Reinfection with Ehrlichia chaffeensis in a liver transplant recipient. Clin Infect Dis (2002) 0.90
Liver transcriptome profiles associated with strain-specific Ehrlichia chaffeensis-induced hepatitis in SCID mice. Infect Immun (2008) 0.89
Ehrlichia chaffeensis induces monocyte inflammatory responses through MyD88, ERK, and NF-κB but not through TRIF, interleukin-1 receptor 1 (IL-1R1)/IL-18R1, or toll-like receptors. Infect Immun (2011) 0.89
Molecular link of different stages of the trematode host of Neorickettsia risticii to Acanthatrium oregonense. Environ Microbiol (2008) 0.89
Subversion of host cell signaling by Orientia tsutsugamushi. Microbes Infect (2011) 0.88
Molecular characterization of Aegyptianella pullorum (Rickettsiales, Anaplasmataceae). J Clin Microbiol (2003) 0.87
High-cholesterol diet facilitates Anaplasma phagocytophilum infection and up-regulates macrophage inflammatory protein-2 and CXCR2 expression in apolipoprotein E-deficient mice. J Infect Dis (2007) 0.87
Ehrlichia type IV secretion effector ECH0825 is translocated to mitochondria and curbs ROS and apoptosis by upregulating host MnSOD. Cell Microbiol (2012) 0.87
Ats-1: a novel bacterial molecule that links autophagy to bacterial nutrition. Autophagy (2013) 0.87
Borrelia burgdorferi oxidative stress regulator BosR directly represses lipoproteins primarily expressed in the tick during mammalian infection. Mol Microbiol (2013) 0.85
Subversion of NPC1 pathway of cholesterol transport by Anaplasma phagocytophilum. Cell Microbiol (2012) 0.85
Transcriptional analysis of p30 major outer membrane protein genes of Ehrlichia canis in naturally infected ticks and sequence analysis of p30-10 of E canis from diverse geographic regions. J Clin Microbiol (2003) 0.85
Ehrlichia chaffeensis infection of sika deer, Japan. Emerg Infect Dis (2009) 0.84
The prenylation inhibitor manumycin A reduces the viability of Anaplasma phagocytophilum. J Med Microbiol (2011) 0.83
Ehrlichia chaffeensis uses its surface protein EtpE to bind GPI-anchored protein DNase X and trigger entry into mammalian cells. PLoS Pathog (2013) 0.81
Optimization of proteomic sample preparation procedures for comprehensive protein characterization of pathogenic systems. J Biomol Tech (2008) 0.81
Development of a p28-based PCR assay for Ehrlichia chaffeensis. Mol Cell Probes (2004) 0.81
Molecular detection and characterization of Ehrlichia canis from dogs in Turkey. Berl Munch Tierarztl Wochenschr (2005) 0.80
Antibiotic clearance of Ehrlichia canis from dogs infected by intravenous inoculation of carrier blood. Ann N Y Acad Sci (2008) 0.80
Role of unfolded protein response in lipogenesis. World J Hepatol (2010) 0.80
Cyclic dimeric GMP signaling regulates intracellular aggregation, sessility, and growth of Ehrlichia chaffeensis. Infect Immun (2011) 0.80
Evaluation of peptide- and recombinant protein-based assays for detection of anti-Ehrlichia ewingii antibodies in experimentally and naturally infected dogs. [corrected] Am J Vet Res (2010) 0.80
Cytokine responses in dogs infected with Ehrlichia canis Oklahoma strain. Ann N Y Acad Sci (2005) 0.79
Neorickettsia risticii surface-exposed proteins: proteomics identification, recognition by naturally-infected horses, and strain variations. Vet Res (2011) 0.79
Proteomic analysis of Neorickettsia sennetsu surface-exposed proteins and porin activity of the major surface protein P51. J Bacteriol (2010) 0.79
Identification of 19 polymorphic major outer membrane protein genes and their immunogenic peptides in Ehrlichia ewingii for use in a serodiagnostic assay. Clin Vaccine Immunol (2007) 0.79
Penicillin-binding protein of Ehrlichia chaffeensis: cytokine induction through MyD88-dependent pathway. J Infect Dis (2012) 0.78
Pathologic evidence of ehrlichiosis in calves inoculated with Ehrlichia chaffeensis. Ann N Y Acad Sci (2008) 0.77