Published in CMAJ on March 22, 2006
Efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer's disease: a systematic review and meta-analysis. Clin Interv Aging (2008) 1.72
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Diagnosis and treatment of dementia: 5. Nonpharmacologic and pharmacologic therapy for mild to moderate dementia. CMAJ (2008) 1.15
The clinical meaningfulness of ADAS-Cog changes in Alzheimer's disease patients treated with donepezil in an open-label trial. BMC Neurol (2007) 1.10
Clinical trial design issues in mild to moderate Alzheimer disease. Cogn Behav Neurol (2008) 0.97
Systematic Review: Representativeness of Participants in RCTs of Acetylcholinesterase Inhibitors. PLoS One (2015) 0.84
Defining efficacy in the treatment of overactive bladder syndrome. Rev Urol (2009) 0.84
Validation of an informant-reported web-based data collection to assess dementia symptoms. J Med Internet Res (2012) 0.81
Alzheimer's Disease: Differences of Transdermal versus Oral Treatment on Caregiving Time. Dement Geriatr Cogn Dis Extra (2012) 0.80
Galantamine-ER for the treatment of mild-to-moderate Alzheimer's disease. Clin Interv Aging (2010) 0.79
FITS into practice: translating research into practice in reducing the use of anti-psychotic medication for people with dementia living in care homes. Aging Ment Health (2015) 0.79
An innovative approach to involve patients in measuring treatment effects in drug trials. CMAJ (2006) 0.77
Reporting of patient-centred outcomes in heart failure trials: are patient preferences being ignored? Heart Fail Rev (2015) 0.76
Management of patients with Alzheimer's disease: pharmacological treatment and quality of life. Ther Adv Chronic Dis (2012) 0.75
Patient and caregiver goals for dementia care. Qual Life Res (2016) 0.75
A systematic review to investigate the measurement properties of goal attainment scaling, towards use in drug trials. BMC Med Res Methodol (2016) 0.75
Galantamine was effective in mild-to-moderate Alzheimer disease. ACP J Club (2006) 0.75
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AD2000: donepezil in Alzheimer's disease. Lancet (2004) 1.92
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Size of the treatment effect on cognition of cholinesterase inhibition in Alzheimer's disease. J Neurol Neurosurg Psychiatry (2004) 1.36
Assessing the clinical importance of statistically significant improvement in anti-dementia drug trials. Neuroepidemiology (2001) 1.10
Use of Goal Attainment Scaling to measure treatment effects in an anti-dementia drug trial. Neuroepidemiology (1996) 1.08
Galantamine: therapeutic effects beyond cognition. Dement Geriatr Cogn Disord (2000) 0.99
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The development of a care-giving burden scale. Age Ageing (1994) 0.83
A global clinical measure of fitness and frailty in elderly people. CMAJ (2005) 8.99
Relative fitness and frailty of elderly men and women in developed countries and their relationship with mortality. J Am Geriatr Soc (2005) 4.48
Long-term risks of death and institutionalization of elderly people in relation to deficit accumulation at age 70. J Am Geriatr Soc (2006) 2.91
Prevalence, attributes, and outcomes of fitness and frailty in community-dwelling older adults: report from the Canadian study of health and aging. J Gerontol A Biol Sci Med Sci (2004) 2.67
Operationalizing a frailty index from a standardized comprehensive geriatric assessment. J Am Geriatr Soc (2004) 2.47
Models, definitions, and criteria of frailty. Aging Clin Exp Res (2003) 2.42
The estimation of relative fitness and frailty in community-dwelling older adults using self-report data. J Gerontol A Biol Sci Med Sci (2004) 2.19
Use of lipid-lowering agents, indication bias, and the risk of dementia in community-dwelling elderly people. Arch Neurol (2002) 2.18
Changes in relative fitness and frailty across the adult lifespan: evidence from the Canadian National Population Health Survey. CMAJ (2011) 1.91
The mortality rate as a function of accumulated deficits in a frailty index. Mech Ageing Dev (2002) 1.56
Effect of galantamine on verbal repetition in AD: a secondary analysis of the VISTA trial. Neurology (2007) 1.54
Predicting post-operative delirium in elective orthopaedic patients: the Delirium Elderly At-Risk (DEAR) instrument. Age Ageing (2005) 1.52
The association of fecal incontinence with institutionalization and mortality in older adults. Am J Gastroenterol (2010) 1.38
The accumulation of deficits with age and possible invariants of aging. ScientificWorldJournal (2002) 1.31
Assessment of individual risk of death using self-report data: an artificial neural network compared with a frailty index. J Am Geriatr Soc (2004) 1.27
Evaluation of a frailty index based on a comprehensive geriatric assessment in a population based study of elderly Canadians. Aging Clin Exp Res (2005) 1.23
Improvement and decline in health status from late middle age: modeling age-related changes in deficit accumulation. Exp Gerontol (2007) 1.23
Assessing biological aging: the origin of deficit accumulation. Biogerontology (2013) 1.19
The clinical meaningfulness of ADAS-Cog changes in Alzheimer's disease patients treated with donepezil in an open-label trial. BMC Neurol (2007) 1.10
Analysis of frailty and survival from late middle age in the Beijing Longitudinal Study of Aging. BMC Geriatr (2011) 1.03
General risk factors for dementia: a systematic evidence review. Alzheimers Dement (2007) 1.02
Frailty and survival of rural and urban seniors: results from the Canadian Study of Health and Aging. Aging Clin Exp Res (2007) 1.02
Disease progression in vascular cognitive impairment: cognitive, functional and behavioural outcomes in the Consortium to Investigate Vascular Impairment of Cognition (CIVIC) cohort study. J Neurol Sci (2006) 0.99
Frailty and survival of older Chinese adults in urban and rural areas: results from the Beijing Longitudinal Study of Aging. Arch Gerontol Geriatr (2011) 0.98
Undertreatment of osteoporosis in residents of nursing homes: population-based study with use of the Systematic Assessment of Geriatric Drug Use via Epidemiology (SAGE) database. Endocr Pract (2004) 0.93
Gender differences in the relationship between smoking and frailty: results from the Beijing Longitudinal Study of Aging. J Gerontol A Biol Sci Med Sci (2012) 0.92
A limit to frailty in very old, community-dwelling people: a secondary analysis of the Chinese longitudinal health and longevity study. Age Ageing (2012) 0.92
The Consortium to Investigate Vascular Impairment of Cognition: methods and first findings. Can J Neurol Sci (2003) 0.92
Clinical and radiographic subtypes of vascular cognitive impairment in a clinic-based cohort study. J Neurol Sci (2005) 0.89
Physician supply: future tense. CMAJ (2003) 0.88
The ADAS-cog and clinically meaningful change in the VISTA clinical trial of galantamine for Alzheimer's disease. Int J Geriatr Psychiatry (2010) 0.87
Comparison of EXIT-25 and the Frontal Assessment Battery for evaluation of executive dysfunction in patients attending a memory clinic. Dement Geriatr Cogn Disord (2009) 0.87
Elevated expression of hyaluronic acid binding protein 1 (HABP1)/P32/C1QBP is a novel indicator for lymph node and peritoneal metastasis of epithelial ovarian cancer patients. Tumour Biol (2013) 0.87
The feasibility of performing resistance exercise with acutely ill hospitalized older adults. BMC Geriatr (2003) 0.84
Advances in perfusion magnetic resonance imaging in Alzheimer's disease. Alzheimers Dement (2010) 0.84
Executive dysfunction in vascular cognitive impairment in the consortium to investigate vascular impairment of cognition study. J Neurol Sci (2009) 0.83
Verbal repetition in patients with Alzheimer's disease who receive donepezil. Int J Geriatr Psychiatry (2006) 0.83
Effect of health protective factors on health deficit accumulation and mortality risk in older adults in the Beijing Longitudinal Study of Aging. J Am Geriatr Soc (2014) 0.82
Advances in high-field magnetic resonance spectroscopy in Alzheimer's disease. Curr Alzheimer Res (2014) 0.82
An MRI-based semiquantitative index for the evaluation of brain atrophy and lesions in Alzheimer's disease, mild cognitive impairment and normal aging. Dement Geriatr Cogn Disord (2010) 0.82
An MRI brain atrophy and lesion index to assess the progression of structural changes in Alzheimer's disease, mild cognitive impairment, and normal aging: a follow-up study. J Alzheimers Dis (2011) 0.81
Co-occurrence of cardiometabolic diseases and frailty in older Chinese adults in the Beijing Longitudinal Study of Ageing. Age Ageing (2013) 0.80
Polygala tenuifolia polysaccharide PTP induced apoptosis in ovarian cancer cells via a mitochondrial pathway. Tumour Biol (2014) 0.79
Decreased initiation of usual activities in people with mild-to-moderate Alzheimer's disease: a descriptive analysis from the VISTA clinical trial. Int Psychogeriatr (2008) 0.79
A luminescent cadmium metal-organic framework for sensing of nitroaromatic explosives. Dalton Trans (2015) 0.78
Development of an LC-MS method for determination of three active constituents of Shuang-huang-lian injection in rat plasma and its application to the drug interaction study of Shuang-huang-lian freeze-dried powder combined with levofloxacin injection. J Chromatogr B Analyt Technol Biomed Life Sci (2012) 0.78
Verbal repetition in people with mild-to-moderate Alzheimer Disease: a descriptive analysis from the VISTA clinical trial. Alzheimer Dis Assoc Disord (2009) 0.78
Combining structural brain changes improves the prediction of Alzheimer's disease and mild cognitive impairment. Dement Geriatr Cogn Disord (2012) 0.77
A meta-ethnography of paid dementia care workers' perspectives on their jobs. Can Geriatr J (2012) 0.77
Attitudes to aging: a comparison of obituaries in Canada and the U.K. Int Psychogeriatr (2009) 0.77
A gallogermanate zeolite with eleven-membered-ring channels. Angew Chem Int Ed Engl (2013) 0.77
A site directed fMRI approach for evaluating functional status in the anterolateral temporal lobes. Neurosci Res (2006) 0.76
Syntheses, structures and magnetic properties of a family of heterometallic [Mn(II)2Mn(III)2Ln(III)2] clusters. Dalton Trans (2012) 0.76
Cognitive impairment of acute onset in the Consortium to Investigate Vascular Impairment of Cognition (CIVIC) study: occurrence, correlates, and outcomes. Am J Geriatr Psychiatry (2006) 0.76
Self-referential tags in the discourse of people with Alzheimer's disease. Brain Lang (2005) 0.75
Long-Term Motor Recovery After Severe Traumatic Brain Injury: Beyond Established Limits. J Head Trauma Rehabil (2016) 0.75
Primary prevention of dementia. Alzheimers Dement (2007) 0.75
Observation of soliton fission in microstructured fiber. Appl Opt (2012) 0.75
Syntheses and characterizations of heteroatom-containing open-framework aluminophosphates. Dalton Trans (2011) 0.75
Polygala tenuifolia polysaccharide (PTP) inhibits cell proliferation by repressing Bmi-1 expression and downregulating telomerase activity. Tumour Biol (2014) 0.75
Support for PICUs and the PRISM scoring algorithms. Pediatr Crit Care Med (2009) 0.75
In situ Hydrogel Conditioning of Tissue Samples to Enhance the Drug's Sensitivity in Ambient Mass Spectrometry Imaging. Anal Chem (2017) 0.75
Detection versus location judgments in a hidden pattern task: functional MRI and behavioral correlates. J Clin Exp Neuropsychol (2011) 0.75
Prevalence and Characteristics of Pre-Operative Delirium in Hip Fracture Patients. Gerontology (2015) 0.75
Fabrication and catalytic performance of highly stable multifunctional core-shell zeolite composites. Inorg Chem (2013) 0.75
|(C4NH12)4|[M4Al12P16O64] (M = Co, Zn): new heteroatom-containing aluminophosphate molecular sieves with two intersecting 8-ring channels. Inorg Chem (2012) 0.75