Published in Diabetes on April 01, 2006
Intensive insulin therapy is associated with reduced infectious complications in burn patients. Surgery (2008) 2.00
Glucose control in severely thermally injured pediatric patients: what glucose range should be the target? Ann Surg (2010) 1.78
Tight blood glucose control is renoprotective in critically ill patients. J Am Soc Nephrol (2008) 1.67
Intensive insulin therapy in severely burned pediatric patients: a prospective randomized trial. Am J Respir Crit Care Med (2010) 1.53
Insulin resistance postburn: underlying mechanisms and current therapeutic strategies. J Burn Care Res (2008) 1.30
Metabolic and nutritional support of critically ill patients: consensus and controversies. Crit Care (2015) 1.28
The Sick and the Weak: Neuropathies/Myopathies in the Critically Ill. Physiol Rev (2015) 1.20
Hyperglycemia in critical illness: a review. J Diabetes Sci Technol (2009) 1.04
Acute hyperglycemia worsens hepatic ischemia/reperfusion injury in rats. J Gastrointest Surg (2009) 0.96
Hyperglycaemia results from beta-cell dysfunction in critically ill children with respiratory and cardiovascular failure: a prospective observational study. Crit Care (2009) 0.96
Impact of intraoperative hyperglycaemia on renal dysfunction after off-pump coronary artery bypass. Interact Cardiovasc Thorac Surg (2013) 0.96
Burns: where are we standing with propranolol, oxandrolone, recombinant human growth hormone, and the new incretin analogs? Curr Opin Clin Nutr Metab Care (2011) 0.92
Clinical review: Glucose control in severely burned patients - current best practice. Crit Care (2013) 0.89
Intensive insulin therapy in the ICU--reconciling the evidence. Nat Rev Endocrinol (2012) 0.88
Endoplasmic reticulum stress and insulin resistance post-trauma: similarities to type 2 diabetes. J Cell Mol Med (2012) 0.87
Treatment with insulin inhibits poly(ADP-ribose)polymerase activation in a rat model of endotoxemia. Life Sci (2007) 0.85
Insulin decreases inflammatory signal transcription factor expression in primary human liver cells after LPS challenge. Mol Med (2008) 0.84
Injury-induced insulin resistance in adipose tissue. Biochem Biophys Res Commun (2012) 0.84
Insulin modulates the inflammatory granulocyte response to streptococci via phosphatidylinositol 3-kinase. J Immunol (2012) 0.83
What do we need beyond hemoglobin A1c to get the complete picture of glycemia in people with diabetes? Int J Med Sci (2012) 0.82
Bench-to-bedside review: metabolism and nutrition. Crit Care (2008) 0.81
Increased blood flow by insulin infusion targeting normoglycemia in patients with severe sepsis: friend or foe? Crit Care (2010) 0.77
Intensive insulin therapy to maintain normoglycemia after cardiac surgery. HSR Proc Intensive Care Cardiovasc Anesth (2011) 0.76
Insulin promotes T cell recovery in a murine model of autoimmune myocarditis. Clin Exp Immunol (2013) 0.76
Assessment of Blood Glucose and Electrolytes during Cardiopulmonary Bypass in Diabetic and Non-Diabetic Patients of Pakistan. Glob J Health Sci (2016) 0.75
Experimental and clinical evidences for glucose control in intensive care: is infused glucose the key point for study interpretation? Crit Care (2014) 0.75
Pulsatile Hyperglycaemia Induces Vascular Oxidative Stress and GLUT 1 Expression More Potently than Sustained Hyperglycaemia in Rats on High Fat Diet. PLoS One (2016) 0.75
Strict blood glucose control by an artificial endocrine pancreas during hepatectomy may prevent postoperative acute kidney injury. J Artif Organs (2016) 0.75
Hyperglycaemia in critically ill patients: the immune system's sweet tooth. Crit Care (2017) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Early versus late parenteral nutrition in critically ill adults. N Engl J Med (2011) 12.10
Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes. N Engl J Med (2005) 10.16
Intensive insulin therapy for patients in paediatric intensive care: a prospective, randomised controlled study. Lancet (2009) 6.44
Reduced cortisol metabolism during critical illness. N Engl J Med (2013) 6.01
Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr Rev (2008) 5.28
Vitamin D deficiency is highly prevalent in COPD and correlates with variants in the vitamin D-binding gene. Thorax (2009) 4.86
ESPEN Guidelines on Parenteral Nutrition: intensive care. Clin Nutr (2009) 4.11
Serum potassium levels and mortality in acute myocardial infarction. JAMA (2012) 4.09
Nutrition in the acute phase of critical illness. N Engl J Med (2014) 4.02
Management of hyperglycemia in hospitalized patients in non-critical care setting: an endocrine society clinical practice guideline. J Clin Endocrinol Metab (2012) 4.02
High doses of vitamin D to reduce exacerbations in chronic obstructive pulmonary disease: a randomized trial. Ann Intern Med (2012) 3.99
Tight blood glucose control with insulin in the ICU: facts and controversies. Chest (2007) 3.79
Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma. Am J Respir Cell Mol Biol (2003) 3.60
Immunoregulation by 1,25-dihydroxyvitamin D3: basic concepts. J Steroid Biochem Mol Biol (2005) 3.44
Vitamin D: modulator of the immune system. Curr Opin Pharmacol (2010) 3.31
Neurocognitive development of children 4 years after critical illness and treatment with tight glucose control: a randomized controlled trial. JAMA (2012) 3.16
Dynamic characteristics of blood glucose time series during the course of critical illness: effects of intensive insulin therapy and relative association with mortality. Crit Care Med (2010) 3.16
Concern Guidelines for pre-operative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery. Eur Heart J (2009) 3.14
Initiation and execution of lipotoxic ER stress in pancreatic beta-cells. J Cell Sci (2008) 2.99
Durability of mitral valve repair in Barlow disease versus fibroelastic deficiency. J Thorac Cardiovasc Surg (2008) 2.91
Insulin degludec versus insulin glargine in insulin-naive patients with type 2 diabetes: a 1-year, randomized, treat-to-target trial (BEGIN Once Long). Diabetes Care (2012) 2.89
Impact of early parenteral nutrition on muscle and adipose tissue compartments during critical illness. Crit Care Med (2013) 2.81
Acute outcomes and 1-year mortality of intensive care unit-acquired weakness. A cohort study and propensity-matched analysis. Am J Respir Crit Care Med (2014) 2.68
Recurrence of mitral valve regurgitation after mitral valve repair in degenerative valve disease. Circulation (2003) 2.67
Amino acid concentrations in critically ill children following cardiac surgery*. Pediatr Crit Care Med (2014) 2.65
A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death. EMBO J (2012) 2.45
Leaf mitochondria modulate whole cell redox homeostasis, set antioxidant capacity, and determine stress resistance through altered signaling and diurnal regulation. Plant Cell (2003) 2.22
Impact of intensive insulin therapy on neuromuscular complications and ventilator dependency in the medical intensive care unit. Am J Respir Crit Care Med (2006) 2.22
Sexual dysfunction in women with type 1 diabetes: a controlled study. Diabetes Care (2002) 2.20
Cytomegalovirus serostatus and outcome in nonimmunocompromised critically ill patients. Crit Care Med (2012) 2.14
Intensive insulin therapy protects the endothelium of critically ill patients. J Clin Invest (2005) 2.11
Polymorphisms in innate immunity genes predispose to bacteremia and death in the medical intensive care unit. Crit Care Med (2009) 2.10
Ventricular phosphodiesterase-5 expression is increased in patients with advanced heart failure and contributes to adverse ventricular remodeling after myocardial infarction in mice. Circulation (2009) 2.05
Pressure autoregulation monitoring and cerebral perfusion pressure target recommendation in patients with severe traumatic brain injury based on minute-by-minute monitoring data. J Neurosurg (2014) 2.04
Diabetes mellitus and the metabolic syndrome do not abolish, but might reduce, the cardioprotective effect of ischemic postconditioning. J Thorac Cardiovasc Surg (2013) 2.03
Prosthesis-patient mismatch predicts structural valve degeneration in bioprosthetic heart valves. Circulation (2010) 1.95
Intensive insulin therapy exerts antiinflammatory effects in critically ill patients and counteracts the adverse effect of low mannose-binding lectin levels. J Clin Endocrinol Metab (2003) 1.93
Monocytes from type 2 diabetic patients have a pro-inflammatory profile. 1,25-Dihydroxyvitamin D(3) works as anti-inflammatory. Diabetes Res Clin Pract (2006) 1.84
Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice. J Clin Invest (2012) 1.84
Prevalence and predictors of sexual dysfunction in patients with type 1 diabetes. Diabetes Care (2003) 1.82
Insufficient autophagy contributes to mitochondrial dysfunction, organ failure, and adverse outcome in an animal model of critical illness. Crit Care Med (2013) 1.78
Protection of hepatocyte mitochondrial ultrastructure and function by strict blood glucose control with insulin in critically ill patients. Lancet (2005) 1.78
Vitamin D: a pleiotropic hormone. Kidney Int (2010) 1.76
Clinical review: Consensus recommendations on measurement of blood glucose and reporting glycemic control in critically ill adults. Crit Care (2013) 1.72
Vitamin D and cancer. J Steroid Biochem Mol Biol (2006) 1.72
Risk factors for infective endocarditis and outcome of patients with Staphylococcus aureus bacteremia. Mayo Clin Proc (2007) 1.71
Clinical review: Critical illness polyneuropathy and myopathy. Crit Care (2008) 1.69
Endocrine, metabolic, and morphologic alterations of adipose tissue during critical illness. Crit Care Med (2013) 1.67
Tight blood glucose control is renoprotective in critically ill patients. J Am Soc Nephrol (2008) 1.67
Cellular islet autoimmunity associates with clinical outcome of islet cell transplantation. PLoS One (2008) 1.67
Vitamin D beyond bones in chronic obstructive pulmonary disease: time to act. Am J Respir Crit Care Med (2009) 1.63
Correlation between beta cell mass and glycemic control in type 1 diabetic recipients of islet cell graft. Proc Natl Acad Sci U S A (2006) 1.60
Cortisol response to critical illness: effect of intensive insulin therapy. J Clin Endocrinol Metab (2006) 1.60
Tight glycemic control protects the myocardium and reduces inflammation in neonatal heart surgery. Ann Thorac Surg (2010) 1.59
American College of Endocrinology position statement on inpatient diabetes and metabolic control. Endocr Pract (2004) 1.59
Novel methods to predict increased intracranial pressure during intensive care and long-term neurologic outcome after traumatic brain injury: development and validation in a multicenter dataset. Crit Care Med (2013) 1.58
Modulation of asymmetric dimethylarginine in critically ill patients receiving intensive insulin treatment: a possible explanation of reduced morbidity and mortality? Crit Care Med (2005) 1.58
Muscle atrophy and preferential loss of myosin in prolonged critically ill patients. Crit Care Med (2012) 1.57
Comparison of thrombolysis versus surgery as a first line therapy for prosthetic heart valve thrombosis. Am J Cardiol (2011) 1.56
Increased cardiac expression of tissue inhibitor of metalloproteinase-1 and tissue inhibitor of metalloproteinase-2 is related to cardiac fibrosis and dysfunction in the chronic pressure-overloaded human heart. Circulation (2005) 1.55
Association between elevated blood glucose and outcome in acute heart failure: results from an international observational cohort. J Am Coll Cardiol (2013) 1.55
ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death. Autophagy (2013) 1.55
Vitamin D and diabetes. Endocrinol Metab Clin North Am (2010) 1.52
Reducing mortality in sepsis: new directions. Crit Care (2002) 1.52
Effects of levosimendan on right ventricular function and ventriculovascular coupling in open chest pigs. Crit Care Med (2003) 1.50
Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-gamma-induced apoptosis in primary pancreatic beta-cells. J Biol Chem (2005) 1.50
Reduced activation and increased inactivation of thyroid hormone in tissues of critically ill patients. J Clin Endocrinol Metab (2003) 1.50
Regulation of the somatotropic axis by intensive insulin therapy during protracted critical illness. J Clin Endocrinol Metab (2004) 1.50
STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation. J Biol Chem (2010) 1.49
Effect of insulin therapy on coagulation and fibrinolysis in medical intensive care patients. Crit Care Med (2008) 1.49
Outcome of patients requiring valve surgery during active infective endocarditis. Ann Thorac Surg (2008) 1.47
American College of Endocrinology position statement on inpatient diabetes and metabolic control. Endocr Pract (2004) 1.47
Visualizing the pressure and time burden of intracranial hypertension in adult and paediatric traumatic brain injury. Intensive Care Med (2015) 1.44
Neuropathological Correlates of Hyperglycemia During Prolonged Polymicrobial Sepsis in Mice. Shock (2015) 1.43