Interleukin-10 and chronic liver disease.

PubWeight™: 0.82‹?›

🔗 View Article (PMC 4124340)

Published in World J Gastroenterol on March 21, 2006

Authors

Li-Juan Zhang1, Xiao-Zhong Wang

Author Affiliations

1: Department of Gastroenterology, Union Hospital of Fujian Medical University, Fuzhou 350001, Fujian Province, China.

Articles cited by this

Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol (2001) 25.63

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med (1989) 15.15

In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J Exp Med (2002) 5.28

Local control of the immune response in the liver. Immunol Rev (2000) 3.01

Cytokine gene polymorphism in human disease: on-line databases. Genes Immun (1999) 2.86

Interleukin 10 treatment reduces fibrosis in patients with chronic hepatitis C: a pilot trial of interferon nonresponders. Gastroenterology (2000) 2.83

The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain. J Leukoc Biol (2004) 2.81

The orphan receptor CRF2-4 is an essential subunit of the interleukin 10 receptor. J Exp Med (1998) 2.55

Cytokine receptors and signaling in hepatic stellate cells. Semin Liver Dis (2001) 2.35

Sympathetic activation triggers systemic interleukin-10 release in immunodepression induced by brain injury. Nat Med (1998) 2.30

The p38 mitogen-activated kinase pathway regulates the human interleukin-10 promoter via the activation of Sp1 transcription factor in lipopolysaccharide-stimulated human macrophages. J Biol Chem (2001) 2.23

Safety and efficacy of recombinant human interleukin 10 in chronic active Crohn's disease. Crohn's Disease IL-10 Cooperative Study Group. Gastroenterology (2000) 2.21

Interleukin-10 expression and function in experimental murine liver inflammation and fibrosis. Hepatology (1998) 2.19

Interleukin-10 controls neutrophilic infiltration, hepatocyte proliferation, and liver fibrosis induced by carbon tetrachloride in mice. Hepatology (1998) 2.04

Identification and functional characterization of a second chain of the interleukin-10 receptor complex. EMBO J (1997) 2.03

New insights into the molecular mechanism of interleukin-10-mediated immunosuppression. J Leukoc Biol (2004) 1.86

Long-term interleukin 10 therapy in chronic hepatitis C patients has a proviral and anti-inflammatory effect. Hepatology (2003) 1.76

Interleukin 10 promoter region polymorphisms and susceptibility to advanced alcoholic liver disease. Gut (2000) 1.68

Crystal structure of interleukin-10 reveals the functional dimer with an unexpected topological similarity to interferon gamma. Structure (1995) 1.54

Current status and prospects of studies on human genetic alleles associated with hepatitis B virus infection. World J Gastroenterol (2003) 1.54

Interleukin-10 is a growth factor for human melanoma cells and down-regulates HLA class-I, HLA class-II and ICAM-1 molecules. Int J Cancer (1997) 1.50

Influence of interleukin-10 gene promoter polymorphisms on disease progression in patients chronically infected with hepatitis B virus. Am J Gastroenterol (2002) 1.50

Interleukin-10 suppresses hepatic ischemia/reperfusion injury in mice: implications of a central role for nuclear factor kappaB. Hepatology (1999) 1.38

Interleukin-10 gene knock-out mice: a model of chronic inflammation. Clin Immunol Immunopathol (1995) 1.34

Expression of interleukin-10 by in vitro and in vivo activated hepatic stellate cells. J Biol Chem (1998) 1.33

IL-10-mediated suppression of TNF-alpha production is independent of its ability to inhibit NF kappa B activity. Eur J Immunol (1998) 1.33

Microsatellite alleles and single nucleotide polymorphisms (SNP) combine to form four major haplotype families at the human interleukin-10 (IL-10) locus. Genes Immun (1999) 1.32

Interleukin-10 modulates type I collagen and matrix metalloprotease gene expression in cultured human skin fibroblasts. J Clin Invest (1994) 1.28

The functional characterization of interleukin-10 receptor expression on human natural killer cells. Blood (1995) 1.26

Interleukin 10 haplotype associated with increased risk of hepatocellular carcinoma. Hum Mol Genet (2003) 1.20

Functional characterization of human IL-10. Int Arch Allergy Immunol (1992) 1.19

Interleukin 10 (Tenovil) in the prevention of postoperative recurrence of Crohn's disease. Gut (2001) 1.15

Hepatoprotective role of interleukin 10 in galactosamine/lipopolysaccharide mouse liver injury. Gastroenterology (1997) 1.14

IL-10 haplotypes as possible predictors of spontaneous clearance of HCV infection. Cytokine (2004) 1.13

Interleukin 10 polymorphisms as predictors of sustained response in antiviral therapy for chronic hepatitis C infection. Hepatology (2001) 1.13

Anti-IL-10 therapeutic strategy using the immunomodulator AS101 in protecting mice from sepsis-induced death: dependence on timing of immunomodulating intervention. J Immunol (2002) 1.12

Production and role of interleukin-10 in concanavalin A-induced hepatitis in mice. Hepatology (1997) 1.11

IL-10 as a therapeutic strategy in the treatment of rheumatoid arthritis. Rheum Dis Clin North Am (1998) 1.10

Pathogenesis, diagnosis and management of hepatitis C. J Hepatol (2000) 1.06

Modulation of liver injury by interleukin-10. Acta Gastroenterol Belg (2003) 1.05

Primary rat and mouse hepatic stellate cells express the macrophage inhibitor cytokine interleukin-10 during the course of activation In vitro. Hepatology (1998) 1.04

Characterization of interleukin-10 receptor expression on B-cell chronic lymphocytic leukemia cells. Blood (1997) 1.04

Polymorphisms in the interleukin-10, tumor necrosis factor-alpha, and transforming growth factor-beta1 genes in chronic hepatitis C patients treated with interferon and ribavirin. J Hepatol (2002) 1.03

Interleukin 10 reduces lethality and hepatic injury induced by lipopolysaccharide in galactosamine-sensitized mice. Gastroenterology (1996) 1.03

Catecholamines trigger IL-10 release in acute systemic stress reaction by direct stimulation of its promoter/enhancer activity in monocytic cells. J Neuroimmunol (2000) 1.02

Viral and cellular interleukin-10 (IL-10)-related cytokines: from structures to functions. Eur Cytokine Netw (2002) 1.00

Effects of cytokines on carbon tetrachloride-induced hepatic fibrogenesis in rats. World J Gastroenterol (2004) 0.99

Interleukin-10-mediated inhibition of free radical generation in macrophages. Am J Physiol Lung Cell Mol Physiol (2001) 0.98

Mapping of the interleukin-10/interleukin-10 receptor combining site. Protein Sci (1998) 0.95

Repeated concanavalin A challenge in mice induces an interleukin 10-producing phenotype and liver fibrosis. Hepatology (2000) 0.93

Pharmacodynamics of subcutaneous recombinant human interleukin-10 in healthy volunteers. Clin Pharmacol Ther (1997) 0.91

Interleukin-10 inhibits hepatic injury and tumor necrosis factor-alpha and interferon-gamma mRNA expression induced by staphylococcal enterotoxin B or lipopolysaccharide in galactosamine-sensitized mice. J Hepatol (1999) 0.89

Enhanced release of interleukin-10 and soluble tumor necrosis factor receptors as novel principles of methylxanthine action in murine models of endotoxic shock. J Pharmacol Exp Ther (1996) 0.88

Effects of transmitters and interleukin-10 on rat hepatic fibrosis induced by CCl4. World J Gastroenterol (2003) 0.88

IL-10 promoter polymorphisms influence disease severity and course in psoriasis. Genes Immun (2003) 0.87

Expression of insulin-like growth factor 1 and insulin-like growth factor 1 receptor and its intervention by interleukin-10 in experimental hepatic fibrosis. World J Gastroenterol (2003) 0.86

Catecholamines induce IL-10 release in patients suffering from acute myocardial infarction by transactivating its promoter in monocytic but not in T-cells. Mol Cell Biochem (2000) 0.86

Concanavalin A-induced hepatitis in mice is prevented by interleukin (IL)-10 and exacerbated by endogenous IL-10 deficiency. Autoimmunity (1999) 0.85

Hepatic release of interleukin-10 during cardiopulmonary bypass in steroid-pretreated patients. Am Heart J (1997) 0.84

Effect of interleukin-10 and platelet-derived growth factor on expressions of matrix metalloproteinases-2 and tissue inhibitor of metalloproteinases-1 in rat fibrotic liver and cultured hepatic stellate cells. World J Gastroenterol (2004) 0.84

Murine IL-10 gene transfer inhibits established collagen-induced arthritis and reduces adenovirus-mediated inflammatory responses in mouse liver. J Immunol (2001) 0.84

Advances in alcoholic liver disease. Curr Gastroenterol Rep (2004) 0.83

IL-10 receptor and coreceptor expression in quiescent and activated hepatic stellate cells. Am J Physiol Gastrointest Liver Physiol (2002) 0.83

Immunomodulation by interleukin-10 therapy decreases the incidence of relapse and prolongs the relapse-free interval in Psoriasis. J Invest Dermatol (2002) 0.82

Effects of platelet-derived growth factor and interleukin-10 on Fas/Fas-ligand and Bcl-2/Bax mRNA expression in rat hepatic stellate cells in vitro. World J Gastroenterol (2004) 0.82

Evidence for conformationally different states of interleukin-10: binding of a neutralizing antibody enhances accessibility of a hidden epitope. J Mol Recognit (2000) 0.81

Downregulation of cytokine-induced neutrophil chemoattractant and prolongation of rat liver allograft survival by interleukin-10. Surg Today (1998) 0.80

Effects of single intravenous doses of recombinant human interleukin-10 on subsets of circulating leukocytes in humans. Immunopharmacology (1999) 0.79

Low level of interleukin 10 synthesis during liver allograft rejection. Lab Invest (1998) 0.76

Oral tolerance: a new tool for the treatment of gastrointestinal inflammatory disorders and liver-directed gene therapy. Can J Gastroenterol (1999) 0.76

Articles by these authors

miR-29a and miR-142-3p downregulation and diagnostic implication in human acute myeloid leukemia. Mol Biol Rep (2011) 1.15

Effects of cytokines on carbon tetrachloride-induced hepatic fibrogenesis in rats. World J Gastroenterol (2004) 0.99

Antifibrotic effects of interleukin-10 on experimental hepatic fibrosis. Hepatogastroenterology (2008) 0.98

12-lipoxygenase induces apoptosis of human gastric cancer AGS cells via the ERK1/2 signal pathway. Dig Dis Sci (2007) 0.93

Nimesulide inhibits proliferation via induction of apoptosis and cell cycle arrest in human gastric adenocarcinoma cell line. World J Gastroenterol (2003) 0.89

Expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 in hepatic stellate cells during rat hepatic fibrosis and its intervention by IL-10. World J Gastroenterol (2005) 0.88

Therapeutic effect of interleukin-10 on CCl4-induced hepatic fibrosis in rats. World J Gastroenterol (2006) 0.88

Selective leukemia cell death by activation of the double-stranded RNA-dependent protein kinase PKR. Int J Mol Med (2011) 0.87

Construction of IL-2 gene-modified human hepatocyte and its cultivation with microcarrier. World J Gastroenterol (2003) 0.85

Hydrogen-bonding-induced planar, rigid, and zigzag oligoanthranilamides. Synthesis, characterization, and self-assembly of a metallocyclophane. J Org Chem (2004) 0.85

Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. Asian Pac J Cancer Prev (2013) 0.84

Effect of interleukin-10 and platelet-derived growth factor on expressions of matrix metalloproteinases-2 and tissue inhibitor of metalloproteinases-1 in rat fibrotic liver and cultured hepatic stellate cells. World J Gastroenterol (2004) 0.84

Relationship between transforming growth factor beta1 and anti-fibrotic effect of interleukin-10. World J Gastroenterol (2006) 0.82

Hepatitis B virus X protein induces apoptosis and cell cycle deregulation through interfering with DNA repair and checkpoint responses. Hepatol Res (2007) 0.81

[Clinical significance of multi-slice spiral CT angiography in radical resection of gastric cancer]. Zhonghua Wei Chang Wai Ke Za Zhi (2011) 0.81

Hydrazide-based quadruply hydrogen-bonded heterodimers. Structure, assembling selectivity, and supramolecular substitution. J Am Chem Soc (2003) 0.81

A novel NKX2-5 mutation in familial ventricular septal defect. Int J Mol Med (2010) 0.80

Possible mechanism for hepatitis B virus X gene to induce apoptosis of hepatocytes. World J Gastroenterol (2005) 0.80

Effects of interleukin-10 on activation and apoptosis of hepatic stellate cells in fibrotic rat liver. World J Gastroenterol (2006) 0.79

Cytochrome C oxidase III interacts with hepatitis B virus X protein in vivo by yeast two-hybrid system. World J Gastroenterol (2004) 0.78

Apoptosis and its pathway in X gene-transfected HepG2 cells. World J Gastroenterol (2005) 0.78

Transfection and expression of hepatitis B virus x gene and its effect on apoptosis in HL-7702 cells. World J Gastroenterol (2004) 0.78

Alternative splicing of apoptosis-related genes in imatinib-treated K562 cells identified by exon array analysis. Int J Mol Med (2011) 0.78

Cooperative inhibitory effects of antisense oligonucleotide of cell adhesion molecules and cimetidine on cancer cell adhesion. World J Gastroenterol (2004) 0.77

Effect of IL-10 on the expression of HSC growth factors in hepatic fibrosis rat. World J Gastroenterol (2005) 0.76

Interleukin-10 gene modification attenuates hepatocyte activation of rat hepatic stellate cells in vitro. Mol Med Rep (2012) 0.76

Association of a methylene tetrahydrofolate reductase C677T polymorphism with several blood chemical levels in a Chinese population. Genet Test Mol Biomarkers (2015) 0.76

[Phenylhexyl isothiocyanate (PHI) regulates histone methylation and acetylation and induces apoptosis in SMMC-7721 cells]. Zhonghua Gan Zang Bing Za Zhi (2010) 0.76

Aberrant expression of splicing factors in newly diagnosed acute myeloid leukemia. Onkologie (2012) 0.75

Poly[[tetra-aquadi-μ4-fumarato-μ2-oxalato-dierbium(III)] tetra-hydrate]. Acta Crystallogr Sect E Struct Rep Online (2012) 0.75

[Effect and possible mechanism of HnRNP E2 decoy RNA on proliferation of K562 leukemia cells]. Ai Zheng (2006) 0.75

Functional dyspepsia of ulcer-dysmotility type: clinical incidence and therapeutic strategy. World J Gastroenterol (1998) 0.75

[The effect of IL-10 on proliferation of primary cultured hepatocytes]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi (2008) 0.75

[Effects of sodium butyrate on proliferation and differentiation of human gastric carcinoma cell line AGS]. Ai Zheng (2008) 0.75

[Regulatory effect of STAT5 decoy oligonucleotides on trans-activation of bcl-x gene promoter in K562 cells]. Ai Zheng (2005) 0.75

[Effects of IL-10 and PDGF-BB on expression of EGF and bFGF mRNA in hepatic stellate cells]. Zhonghua Gan Zang Bing Za Zhi (2004) 0.75

Identification of differential expressed PE exosomal miRNA in lung adenocarcinoma, tuberculosis, and other benign lesions. Medicine (Baltimore) (2017) 0.75

[Screening hepatitis B virus X-interactive proteins by yeast two-hybrid system]. Ai Zheng (2004) 0.75

[Effect of gastrin on tyrosine phosphorylation of focal adhesion kinase in human gastric cancer cell line SGC7901]. Ai Zheng (2008) 0.75

[Effect of targeted activation of protein kinase PKR on proliferation of leukemia cell line K562 and its mechanism]. Ai Zheng (2007) 0.75

[Targeted blockage of RNA binding protein E2 by decoy RNA induces the granulocytic differentiation of K562 cells]. Zhonghua Xue Ye Xue Za Zhi (2008) 0.75

Competitive priming PCR: a versatile method to generate cohesive terminus. Mol Biol Rep (2009) 0.75