NK-2 receptor agonists and antagonists.

PubWeight™: 0.85‹?›

🔗 View Article (PMID 1659293)

Published in Ann N Y Acad Sci on January 01, 1991

Authors

C A Maggi1, R Patacchini, M Astolfi, P Rovero, S Giuliani, A Giachetti

Author Affiliations

1: Department of Pharmacology, A. Menarini Pharmaceuticals, Florence, Italy.

Articles by these authors

Muscarinic receptor subtypes: M1 and M2 biochemical and functional characterization. Life Sci (1982) 3.02

Tachykinin receptors and tachykinin receptor antagonists. J Auton Pharmacol (1993) 1.92

Cardioselective profile of AF-DX 116, a muscarine M2 receptor antagonist. Life Sci (1986) 1.80

Tachykinins and calcitonin gene-related peptide (CGRP) as co-transmitters released from peripheral endings of sensory nerves. Prog Neurobiol (1995) 1.70

Renal differentiation of amniotic fluid stem cells. Cell Prolif (2007) 1.51

The effect of omega conotoxin GVIA, a peptide modulator of the N-type voltage sensitive calcium channels, on motor responses produced by activation of efferent and sensory nerves in mammalian smooth muscle. Naunyn Schmiedebergs Arch Pharmacol (1988) 1.47

Spontaneous release of acetylcholine from autonomic nerves in the bladder. Br J Pharmacol (2009) 1.47

Sneddon syndrome presenting with hemicranic attacks: a case report. Acta Neurol Scand (1991) 1.39

The actions of kinin antagonists on B1 and B2 receptor systems. Eur J Pharmacol (1986) 1.31

Competitive antagonists discriminate between NK2 tachykinin receptor subtypes. Br J Pharmacol (1990) 1.26

Molecular and clinical remissions in multiple myeloma: role of autologous and allogeneic transplantation of hematopoietic cells. J Clin Oncol (1999) 1.26

Potent contractile effect of endothelin in isolated guinea-pig airways. Eur J Pharmacol (1989) 1.25

The activity of peptides of the endothelin family in various mammalian smooth muscle preparations. Eur J Pharmacol (1989) 1.24

In vivo evidence for tachykininergic transmission using a new NK-2 receptor-selective antagonist, MEN 10,376. J Pharmacol Exp Ther (1991) 1.24

Role of NK1 tachykinin receptors in thermonociception: effect of (+/-)-CP 96,345, a non-peptide substance P antagonist, on the hot plate test in mice. Neurosci Lett (1991) 1.22

Analysis of factors involved in determining urinary bladder voiding cycle in urethan-anesthetized rats. Am J Physiol (1986) 1.22

European consensus meeting of ARM-Net members concerning diagnosis and early management of newborns with anorectal malformations. Tech Coloproctol (2015) 1.22

VAMPIRE: Vessel assessment and measurement platform for images of the REtina. Conf Proc IEEE Eng Med Biol Soc (2011) 1.21

The C-terminal hexapeptide, endothelin-(16-21), discriminates between different endothelin receptors. Eur J Pharmacol (1989) 1.17

Vasoactive intestinal polypeptide in brain: localization in and release from isolated nerve terminals. Proc Natl Acad Sci U S A (1977) 1.16

Inactivation of tumor suppressor genes, p53 and Rb1, in plasma cell dyscrasias. Leukemia (1994) 1.16

A potent and selective agonist for NK-2 tachykinin receptor. Peptides (1989) 1.14

Human alpha-calcitonin gene-related peptide-(8-37) as an antagonist of exogenous and endogenous calcitonin gene-related peptide. Eur J Pharmacol (1991) 1.13

The antagonism induced by ruthenium red of the actions of capsaicin on the peripheral terminals of sensory neurons: further studies. Eur J Pharmacol (1988) 1.12

Prostanoids modulate reflex micturition by acting through capsaicin-sensitive afferents. Eur J Pharmacol (1988) 1.11

The neurotransmitter role of calcitonin gene-related peptide in the rat and guinea-pig ureter: effect of a calcitonin gene-related peptide antagonist and species-related differences in the action of omega conotoxin on calcitonin gene-related peptide release from primary afferents. Neuroscience (1991) 1.11

Biological activity of N-terminal fragments of calcitonin gene-related peptide. Eur J Pharmacol (1990) 1.10

New arylpyrido-diazepine and -thiodiazepine derivatives are potent and highly selective HIV-1 inhibitors targeted at the reverse transcriptase. Antiviral Res (1996) 1.09

A comparison of capsazepine and ruthenium red as capsaicin antagonists in the rat isolated urinary bladder and vas deferens. Br J Pharmacol (1993) 1.09

Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents. Br J Pharmacol (2009) 1.08

The 'efferent' function of capsaicin-sensitive nerves: ruthenium red discriminates between different mechanisms of activation. Eur J Pharmacol (1989) 1.08

Characterization of nociceptin receptors in the periphery: in vitro and in vivo studies. Naunyn Schmiedebergs Arch Pharmacol (1999) 1.08

Tachykinin antagonists and capsaicin-induced contraction of the rat isolated urinary bladder: evidence for tachykinin-mediated cotransmission. Br J Pharmacol (1991) 1.08

The rat isolated portal vein: a preparation sensitive to neurokinins, particularly neurokinin B. Eur J Pharmacol (1987) 1.08

Characterization of the capsaicin-sensitive component of cyclophosphamide-induced inflammation in the rat urinary bladder. Br J Pharmacol (1994) 1.04

Low pH-induced release of calcitonin gene-related peptide from capsaicin-sensitive sensory nerves: mechanism of action and biological response. Neuroscience (1991) 1.04

Binding and functional characterization of the cardioselective muscarinic antagonist methoctramine. J Pharmacol Exp Ther (1988) 1.03

Studies in vitro of amine uptake mechanisms in heart. Biochem Pharmacol (1966) 1.03

Involvement of 5-hydroxytryptamine1A receptors in the modulation of micturition reflexes in the anesthetized rat. J Pharmacol Exp Ther (1992) 1.03

Evidence for two independent modes of activation of the 'efferent' function of capsaicin-sensitive nerves. Eur J Pharmacol (1988) 1.03

Peripheral effects of neurokinins: functional evidence for the existence of multiple receptors. J Auton Pharmacol (1987) 1.02

Human isolated small intestine: motor responses of the longitudinal muscle to field stimulation and exogenous neuropeptides. Naunyn Schmiedebergs Arch Pharmacol (1989) 1.02

Tachykinin receptors and noncholinergic bronchoconstriction in the guinea-pig isolated bronchi. Am Rev Respir Dis (1991) 1.02

Extrinsic origin of the capsaicin-sensitive innervation of rat duodenum: possible involvement of calcitonin gene-related peptide (CGRP) in the capsaicin-induced activation of intramural non-adrenergic non-cholinergic neurons. Naunyn Schmiedebergs Arch Pharmacol (1986) 1.01

Intestinal epithelial barrier dysfunction in disease and possible therapeutical interventions. Curr Med Chem (2011) 1.01

Contractile response of the human isolated urinary bladder to neurokinins: involvement of NK-2 receptors. Eur J Pharmacol (1988) 1.00

AF-DX 116, a cardioselective muscarinic antagonist. J Pharmacol Exp Ther (1987) 1.00

TT virus levels in the plasma of infected individuals with different hepatic and extrahepatic pathology. J Med Virol (2001) 1.00

A highly selective NK-2 tachykinin receptor antagonist containing D-tryptophan. Eur J Pharmacol (1990) 0.99

A novel nested-PCR strategy for the detection of rearranged immunoglobulin heavy-chain genes in B cell tumors. Leukemia (1997) 0.99

Functional characterization of substance P receptors on cultured human spinal cord astrocytes: synergism of substance P with cytokines in inducing interleukin-6 and prostaglandin E2 production. Glia (1997) 0.99

Cyclophosphamide cystitis in rats: involvement of capsaicin-sensitive primary afferents. J Auton Nerv Syst (1992) 0.98

Simultaneous recording of vesical and urethral pressure in urethane-anesthetized rats: effect of neuromuscular blocking agents on the activity of the external urethral sphincter. J Pharmacol Methods (1991) 0.98

Binding and functional profiles of the selective M1 muscarinic receptor antagonists trihexyphenidyl and dicyclomine. Br J Pharmacol (1986) 0.98

Autoantibodies directed against ribosomal P proteins: use of a multiple antigen peptide as the coating agent in ELISA. J Immunol Methods (1995) 0.97

Sensory nerves, vascular endothelium and neurogenic relaxation of the guinea-pig isolated pulmonary artery. Naunyn Schmiedebergs Arch Pharmacol (1990) 0.97

Neuropeptides as regulators of airway function: vasoactive intestinal peptide and the tachykinins. Physiol Rev (1995) 0.97

Effect of synthetic tachykinin analogues on airway microvascular leakage in rats and guinea-pigs: evidence for the involvement of NK-1 receptors. J Auton Pharmacol (1991) 0.97

(Imidazolylphenyl)formamidines. A structurally novel class of potent histamine H2 receptor antagonists. J Med Chem (1984) 0.97

Further evidence for the existence of NK2 tachykinin receptor subtypes. Br J Pharmacol (1991) 0.96

Bradykinin-induced release of calcitonin gene-related peptide from capsaicin-sensitive nerves in guinea-pig atria: mechanism of action and calcium requirements. Neuroscience (1990) 0.96

In vivo and in vitro pharmacology of SR 48,968, a non-peptide tachykinin NK2 receptor antagonist. Eur J Pharmacol (1993) 0.96

Effect of NG-monomethyl L-arginine (L-NMMA) and NG-nitro L-arginine (L-NOARG) on non-adrenergic non-cholinergic relaxation in the circular muscle of the human ileum. Br J Pharmacol (1991) 0.96

Inhibition of feline immunodeficiency virus infection in vitro by envelope glycoprotein synthetic peptides. Virology (1996) 0.96

The effect of thiorphan and epithelium removal on contractions and tachykinin release produced by activation of capsaicin-sensitive afferents in the guinea-pig isolated bronchus. Naunyn Schmiedebergs Arch Pharmacol (1990) 0.96

Direct evidence that capsaicin-induced plasma protein extravasation is mediated through tachykinin NK1 receptors. Eur J Pharmacol (1991) 0.96

Tachykinins and calcitonin gene-related peptide as co-transmitters in local motor responses produced by sensory nerve activation in the guinea-pig isolated renal pelvis. Neuroscience (1992) 0.96

Comparison of tachykinin NK1 and NK2 receptors in the circular muscle of the guinea-pig ileum and proximal colon. Br J Pharmacol (1994) 0.96