PubRank

Giuseppe D Ciccotosto

Author PubWeight™ 31.80‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export. Nat Med 2012 3.31
2 Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease. Cell 2010 2.46
3 Amyloid-beta as a positive endogenous regulator of release probability at hippocampal synapses. Nat Neurosci 2009 2.31
4 Amyloid-beta peptide (Abeta) neurotoxicity is modulated by the rate of peptide aggregation: Abeta dimers and trimers correlate with neurotoxicity. J Neurosci 2008 1.86
5 Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42. J Neurosci 2005 1.83
6 Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease beta-amyloid. FASEB J 2004 1.29
7 Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation. J Biol Chem 2003 1.14
8 Methylation of the imidazole side chains of the Alzheimer disease amyloid-beta peptide results in abolition of superoxide dismutase-like structures and inhibition of neurotoxicity. J Biol Chem 2005 1.14
9 Copper-mediated amyloid-beta toxicity is associated with an intermolecular histidine bridge. J Biol Chem 2006 1.10
10 Trafficking of a secretory granule membrane protein is sensitive to copper. J Biol Chem 2007 1.09
11 Concentration dependent Cu2+ induced aggregation and dityrosine formation of the Alzheimer's disease amyloid-beta peptide. Biochemistry 2007 1.06
12 Menkes protein contributes to the function of peptidylglycine alpha-amidating monooxygenase. Endocrinology 2003 1.04
13 Correlative studies support lipid peroxidation is linked to PrP(res) propagation as an early primary pathogenic event in prion disease. Brain Res Bull 2005 1.03
14 Gene knockout of amyloid precursor protein and amyloid precursor-like protein-2 increases cellular copper levels in primary mouse cortical neurons and embryonic fibroblasts. J Neurochem 2004 0.99
15 Stabilization of neurotoxic soluble beta-sheet-rich conformations of the Alzheimer's disease amyloid-beta peptide. Biophys J 2007 0.98
16 A domain level interaction network of amyloid precursor protein and Abeta of Alzheimer's disease. Proteomics 2010 0.96
17 Platinum-based inhibitors of amyloid-beta as therapeutic agents for Alzheimer's disease. Proc Natl Acad Sci U S A 2008 0.93
18 The amyloid precursor protein (APP) of Alzheimer disease and its paralog, APLP2, modulate the Cu/Zn-Nitric Oxide-catalyzed degradation of glypican-1 heparan sulfate in vivo. J Biol Chem 2005 0.91
19 Amyloid precursor protein is required for normal function of the rod and cone pathways in the mouse retina. PLoS One 2012 0.86
20 Alleviating transcriptional inhibition of the norepinephrine slc6a2 transporter gene in depolarized neurons. J Neurosci 2010 0.85
21 Suppression of amyloid beta A11 antibody immunoreactivity by vitamin C: possible role of heparan sulfate oligosaccharides derived from glypican-1 by ascorbate-induced, nitric oxide (NO)-catalyzed degradation. J Biol Chem 2011 0.85
22 Stimulus pattern dependence of the Alzheimer's disease amyloid-beta 42 peptide's inhibition of long term potentiation in mouse hippocampal slices. Brain Res 2009 0.83
23 Mild oxidative stress induces redistribution of BACE1 in non-apoptotic conditions and promotes the amyloidogenic processing of Alzheimer's disease amyloid precursor protein. PLoS One 2013 0.81
24 APP involvement in retinogenesis of mice. Acta Neuropathol 2010 0.79
25 Gene knockout of tau expression does not contribute to the pathogenesis of prion disease. J Neuropathol Exp Neurol 2011 0.79
26 Combined deletions of amyloid precursor protein and amyloid precursor-like protein 2 reveal different effects on mouse brain metal homeostasis. Metallomics 2014 0.78
27 Histidine 14 modulates membrane binding and neurotoxicity of the Alzheimer's disease amyloid-beta peptide. J Alzheimers Dis 2010 0.77
28 Neurotoxicity from glutathione depletion is mediated by Cu-dependent p53 activation. Free Radic Biol Med 2007 0.75
29 Oligomerization and toxicity of Aβ fusion proteins. Biochem Biophys Res Commun 2011 0.75