Avril V Somlyo

Author PubWeight™ 47.57‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. Physiol Rev 2003 9.32
2 Angiotensin II, focal adhesion kinase, and PRX1 enhance smooth muscle expression of lipoma preferred partner and its newly identified binding partner palladin to promote cell migration. Circ Res 2007 1.76
3 The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle. Structure 2004 1.45
4 Phosphorylation-dependent autoinhibition of myosin light chain phosphatase accounts for Ca2+ sensitization force of smooth muscle contraction. J Biol Chem 2009 1.32
5 Assessment of contractility of purified smooth muscle cells derived from embryonic stem cells. Stem Cells 2006 1.29
6 RhoA-mediated Ca2+ sensitization in erectile function. J Biol Chem 2002 1.25
7 Cooperativity between the Ras-ERK and Rho-Rho kinase pathways in urokinase-type plasminogen activator-stimulated cell migration. J Biol Chem 2002 1.17
8 Rho-kinase: regulation, (dys)function, and inhibition. Biol Chem 2013 1.17
9 Myocardin is differentially required for the development of smooth muscle cells and cardiomyocytes. Am J Physiol Heart Circ Physiol 2011 1.10
10 Thromboxane A2-induced bi-directional regulation of cerebral arterial tone. J Biol Chem 2008 1.08
11 Signal transduction through the RhoA/Rho-kinase pathway in smooth muscle. J Muscle Res Cell Motil 2004 1.07
12 Cep57, a multidomain protein with unique microtubule and centrosomal localization domains. Biochem J 2008 1.06
13 Smooth and cardiac muscle-selective knock-out of Kruppel-like factor 4 causes postnatal death and growth retardation. J Biol Chem 2010 1.06
14 p63RhoGEF couples Gα(q/11)-mediated signaling to Ca2+ sensitization of vascular smooth muscle contractility. Circ Res 2011 1.05
15 On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF. BMC Struct Biol 2009 1.04
16 The cAMP-responsive Rap1 guanine nucleotide exchange factor, Epac, induces smooth muscle relaxation by down-regulation of RhoA activity. J Biol Chem 2011 1.04
17 Telokin mediates Ca2+-desensitization through activation of myosin phosphatase in phasic and tonic smooth muscle. J Muscle Res Cell Motil 2005 1.00
18 LPP, a LIM protein highly expressed in smooth muscle. Am J Physiol Cell Physiol 2003 0.99
19 Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle. J Biol Chem 2008 0.96
20 Myosin regulatory light chain phosphorylation and strain modulate adenosine diphosphate release from smooth muscle Myosin. Biophys J 2004 0.95
21 The actin-associated protein Palladin is required for development of normal contractile properties of smooth muscle cells derived from embryoid bodies. J Biol Chem 2008 0.94
22 Cryo-atomic force microscopy of unphosphorylated and thiophosphorylated single smooth muscle myosin molecules. J Biol Chem 2003 0.93
23 The actin associated protein palladin is important for the early smooth muscle cell differentiation. PLoS One 2010 0.93
24 Modulation of Ca2+ sensitivity by cyclic nucleotides in smooth muscle from protein kinase G-deficient mice. J Biol Chem 2003 0.89
25 Uncoupling of GPCR and RhoA-induced Ca2+-sensitization of chicken amnion smooth muscle lacking CPI-17. FEBS Lett 2004 0.89
26 New roads leading to Ca2+ sensitization. Circ Res 2002 0.88
27 Mechanical properties of the extracellular matrix alter expression of smooth muscle protein LPP and its partner palladin; relationship to early atherosclerosis and vascular injury. J Muscle Res Cell Motil 2009 0.87
28 Fluorescence linked enzyme chemoproteomic strategy for discovery of a potent and selective DAPK1 and ZIPK inhibitor. ACS Chem Biol 2013 0.87
29 Insights into the molecular activation mechanism of the RhoA-specific guanine nucleotide exchange factor, PDZRhoGEF. J Biol Chem 2011 0.87
30 Expression of CPI-17 in smooth muscle during embryonic development and in neointimal lesion formation. Histochem Cell Biol 2009 0.86
31 Cyclic GMP regulation of myosin phosphatase: a new piece for the puzzle? Circ Res 2007 0.86
32 Agonist-induced Ca2+ sensitization in smooth muscle: redundancy of Rho guanine nucleotide exchange factors (RhoGEFs) and response kinetics, a caged compound study. J Biol Chem 2013 0.86
33 Intracellular chloride accumulation and subcellular elemental distribution during atrial fibrillation. Circulation 2003 0.84
34 p63RhoGEF: a new switch for G(q)-mediated activation of smooth muscle. Trends Cardiovasc Med 2012 0.83
35 ANG II type 2 receptor regulates smooth muscle growth and force generation in late fetal mouse development. Am J Physiol Heart Circ Physiol 2004 0.81
36 Molecular mechanism of telokin-mediated disinhibition of myosin light chain phosphatase and cAMP/cGMP-induced relaxation of gastrointestinal smooth muscle. J Biol Chem 2012 0.80
37 Identification of quercitrin as an inhibitor of the p90 S6 ribosomal kinase (RSK): structure of its complex with the N-terminal domain of RSK2 at 1.8 Å resolution. Acta Crystallogr D Biol Crystallogr 2013 0.78
38 The sarcoplasmic reticulum: then and now. Novartis Found Symp 2002 0.77
39 Calcium content of peripheral and central mitochondria in the guinea pig myocardium: electron probe analysis. Cell Calcium 2003 0.77
40 The p90 ribosomal S6 kinase (RSK) is a mediator of smooth muscle contractility. PLoS One 2013 0.76
41 Automated electron tomography with scanning transmission electron microscopy. J Microsc 2007 0.75