Published in Int J Parasitol on March 10, 2006
Mechanisms of microbial traversal of the blood-brain barrier. Nat Rev Microbiol (2008) 2.04
Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India. Malar J (2008) 2.00
Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children. PLoS One (2009) 1.93
The neuropathology of fatal cerebral malaria in malawian children. Am J Pathol (2011) 1.79
The role of animal models for research on severe malaria. PLoS Pathog (2012) 1.76
Irf8-regulated genomic responses drive pathological inflammation during cerebral malaria. PLoS Pathog (2013) 1.59
Whole blood angiopoietin-1 and -2 levels discriminate cerebral and severe (non-cerebral) malaria from uncomplicated malaria. Malar J (2009) 1.59
Combinations of host biomarkers predict mortality among Ugandan children with severe malaria: a retrospective case-control study. PLoS One (2011) 1.55
Blood coagulation, inflammation, and malaria. Microcirculation (2008) 1.54
Sequestration and microvascular congestion are associated with coma in human cerebral malaria. J Infect Dis (2011) 1.52
Plasmodium falciparum-infected erythrocytes induce NF-kappaB regulated inflammatory pathways in human cerebral endothelium. Blood (2009) 1.46
Endothelium-based biomarkers are associated with cerebral malaria in Malawian children: a retrospective case-control study. PLoS One (2010) 1.43
Induction of blood brain barrier tight junction protein alterations by CD8 T cells. PLoS One (2008) 1.38
Neuroimmunological blood brain barrier opening in experimental cerebral malaria. PLoS Pathog (2012) 1.35
Inhibition of histamine-mediated signaling confers significant protection against severe malaria in mouse models of disease. J Exp Med (2008) 1.25
CD8 T cell-initiated vascular endothelial growth factor expression promotes central nervous system vascular permeability under neuroinflammatory conditions. J Immunol (2009) 1.17
Plasmodium falciparum adhesion on human brain microvascular endothelial cells involves transmigration-like cup formation and induces opening of intercellular junctions. PLoS Pathog (2010) 1.16
A rapid murine coma and behavior scale for quantitative assessment of murine cerebral malaria. PLoS One (2010) 1.10
Children with retinopathy-negative cerebral malaria: a pathophysiologic puzzle. Pediatr Infect Dis J (2011) 1.08
Src-family kinase dependent disruption of endothelial barrier function by Plasmodium falciparum merozoite proteins. Blood (2007) 1.07
Brain swelling and mannitol therapy in adult cerebral malaria: a randomized trial. Clin Infect Dis (2011) 1.07
Pathogenesis of cerebral malaria--inflammation and cytoadherence. Front Cell Infect Microbiol (2014) 1.06
Cerebral malaria: mysteries at the blood-brain barrier. Virulence (2012) 1.05
Altered phenotype and gene transcription in endothelial cells, induced by Plasmodium falciparum-infected red blood cells: pathogenic or protective? Int J Parasitol (2007) 1.05
Cerebral malaria: we have come a long way. Am J Pathol (2012) 1.04
Caspase-1 activation of interleukin-1β (IL-1β) and IL-18 is dispensable for induction of experimental cerebral malaria. Infect Immun (2011) 1.02
Coma in fatal adult human malaria is not caused by cerebral oedema. Malar J (2011) 1.02
S1P is associated with protection in human and experimental cerebral malaria. Mol Med (2011) 1.02
Plasmodium falciparum intercellular adhesion molecule-1-based cytoadherence-related signaling in human endothelial cells. J Infect Dis (2007) 0.99
A novel carbon monoxide-releasing molecule fully protects mice from severe malaria. Antimicrob Agents Chemother (2011) 0.99
CNS hypoxia is more pronounced in murine cerebral than noncerebral malaria and is reversed by erythropoietin. Am J Pathol (2011) 0.97
Experimental cerebral malaria pathogenesis--hemodynamics at the blood brain barrier. PLoS Pathog (2014) 0.97
Contrasting pediatric and adult cerebral malaria: the role of the endothelial barrier. Virulence (2013) 0.96
Investigating the Pathogenesis of Severe Malaria: A Multidisciplinary and Cross-Geographical Approach. Am J Trop Med Hyg (2015) 0.96
A morphometric and histological study of placental malaria shows significant changes to villous architecture in both Plasmodium falciparum and Plasmodium vivax infection. Malar J (2014) 0.95
Epithelial cell coculture models for studying infectious diseases: benefits and limitations. J Biomed Biotechnol (2011) 0.94
CD8 T cell-initiated blood-brain barrier disruption is independent of neutrophil support. J Immunol (2012) 0.94
A hematopoietic contribution to microhemorrhage formation during antiviral CD8 T cell-initiated blood-brain barrier disruption. J Neuroinflammation (2012) 0.94
Malaria parasite tyrosyl-tRNA synthetase secretion triggers pro-inflammatory responses. Nat Commun (2011) 0.94
Induction of the vascular endothelial growth factor pathway in the brain of adults with fatal falciparum malaria is a non-specific response to severe disease. Histopathology (2010) 0.93
The Impact of HIV and Malaria Coinfection: What Is Known and Suggested Venues for Further Study. Interdiscip Perspect Infect Dis (2009) 0.92
Hyperbaric oxygen prevents early death caused by experimental cerebral malaria. PLoS One (2008) 0.91
Opposed circulating plasma levels of endothelin-1 and C-type natriuretic peptide in children with Plasmodium falciparum malaria. Malar J (2008) 0.91
Network-based gene prediction for Plasmodium falciparum malaria towards genetics-based drug discovery. BMC Genomics (2015) 0.91
Metabolic acidosis induced by Plasmodium falciparum intraerythrocytic stages alters blood-brain barrier integrity. J Cereb Blood Flow Metab (2010) 0.91
Complement factors C1q, C3 and C5 in brain and serum of mice with cerebral malaria. Malar J (2008) 0.89
Amplification of P. falciparum Cytoadherence through induction of a pro-adhesive state in host endothelium. PLoS One (2011) 0.89
Passage of parasites across the blood-brain barrier. Virulence (2012) 0.88
A clinicopathological correlation of the expression of the angiopoietin-Tie-2 receptor pathway in the brain of adults with Plasmodium falciparum malaria. Malar J (2013) 0.87
Erythropoietin and its receptors in the brainstem of adults with fatal falciparum malaria. Malar J (2009) 0.87
Haemozoin induces early cytokine-mediated lysozyme release from human monocytes through p38 MAPK- and NF-kappaB-dependent mechanisms. PLoS One (2012) 0.87
Vitamin D inhibits the occurrence of experimental cerebral malaria in mice by suppressing the host inflammatory response. J Immunol (2014) 0.85
Involvement of inflammatory chemokines in survival of human monocytes fed with malarial pigment. Infect Immun (2010) 0.85
Host matrix metalloproteinases in cerebral malaria: new kids on the block against blood-brain barrier integrity? Fluids Barriers CNS (2014) 0.84
Perforin competent CD8 T cells are sufficient to cause immune-mediated blood-brain barrier disruption. PLoS One (2014) 0.83
Protective role of brain water channel AQP4 in murine cerebral malaria. Proc Natl Acad Sci U S A (2012) 0.83
Erythropoietin protects against murine cerebral malaria through actions on host cellular immunity. Infect Immun (2013) 0.82
Inflammatory changes in the central nervous system are associated with behavioral impairment in Plasmodium berghei (strain ANKA)-infected mice. Exp Parasitol (2010) 0.82
Matrix Metalloproteinase-9 and Haemozoin: Wedding Rings for Human Host and Plasmodium falciparum Parasite in Complicated Malaria. J Trop Med (2011) 0.82
A new hypothesis on the manifestation of cerebral malaria: the secret is in the liver. Med Hypotheses (2013) 0.81
Theiler's murine encephalomyelitis virus as an experimental model system to study the mechanism of blood-brain barrier disruption. J Neurovirol (2013) 0.81
Cytoadherence and severe malaria. Malays J Med Sci (2012) 0.81
Protective or pathogenic effects of vascular endothelial growth factor (VEGF) as potential biomarker in cerebral malaria. Pathog Glob Health (2014) 0.81
Lactate transport and receptor actions in cerebral malaria. Front Neurosci (2014) 0.80
Magnetic resonance imaging during life: the key to unlock cerebral malaria pathogenesis? Malar J (2014) 0.80
P. falciparum isolate-specific distinct patterns of induced apoptosis in pulmonary and brain endothelial cells. PLoS One (2014) 0.80
The Impact of HIV Coinfection on Cerebral Malaria Pathogenesis. J Neuroparasitology (2012) 0.79
Pathophysiological Mechanisms in Gaseous Therapies for Severe Malaria. Infect Immun (2016) 0.79
Electron microscopic features of brain edema in rodent cerebral malaria in relation to glial fibrillary acidic protein expression. Int J Clin Exp Pathol (2014) 0.78
Cerebral malaria: insights from host-parasite protein-protein interactions. Malar J (2010) 0.78
Membrane compartmentalization in Southeast Asian ovalocytosis red blood cells. Br J Haematol (2011) 0.77
Fatal cerebral malaria: a venous efflux problem. Front Cell Infect Microbiol (2014) 0.76
Modulatory effects of perforin gene dosage on pathogen-associated blood-brain barrier (BBB) disruption. J Neuroinflammation (2016) 0.76
Quantitative trait loci analysis reveals candidate genes implicated in regulating functional deficit and CNS vascular permeability in CD8 T cell-initiated blood-brain barrier disruption. BMC Genomics (2013) 0.76
Indocyanine Green Liposomes for Diagnosis and Therapeutic Monitoring of Cerebral Malaria. Theranostics (2016) 0.76
Plasmodium-infected erythrocytes (pRBC) induce endothelial cell apoptosis via a heme-mediated signaling pathway. Drug Des Devel Ther (2016) 0.76
Myocardial Dysfunction: A Primary Cause of Death Due To Severe Malaria in A Plasmodium falciparum-Infected Humanized Mouse Model. Iran J Parasitol (2013) 0.76
Disruption of Parasite hmgb2 Gene Attenuates Plasmodium berghei ANKA Pathogenicity. Infect Immun (2015) 0.75
A Functional IL22 Polymorphism (rs2227473) Is Associated with Predisposition to Childhood Cerebral Malaria. Sci Rep (2017) 0.75
Possible roles of amyloids in malaria pathophysiology. Future Sci OA (2015) 0.75
Transcriptomic profiling of microglia reveals signatures of cell activation and immune response, during experimental cerebral malaria. Sci Rep (2016) 0.75
Toxoplasma gondii upregulates interleukin-12 to prevent Plasmodium berghei-induced experimental cerebral malaria. Infect Immun (2014) 0.75
Young Sprague Dawley rats infected by Plasmodium berghei: A relevant experimental model to study cerebral malaria. PLoS One (2017) 0.75
Cytokines and Chemokines in Cerebral Malaria Pathogenesis. Front Cell Infect Microbiol (2017) 0.75
The murine cerebral malaria phenomenon. Trends Parasitol (2009) 5.62
An ultrastructural study of the brain in fatal Plasmodium falciparum malaria. Am J Trop Med Hyg (2003) 2.47
Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease. Cancer Res (2002) 1.98
Lethal malaria: Marchiafava and Bignami were right. J Infect Dis (2013) 1.88
Host response to malaria during pregnancy: placental monocyte recruitment is associated with elevated beta chemokine expression. J Immunol (2003) 1.55
Mutations in the AXIN1 gene in advanced prostate cancer. Eur Urol (2008) 1.53
Sequestration and microvascular congestion are associated with coma in human cerebral malaria. J Infect Dis (2011) 1.52
A quantitative ultrastructural study of renal pathology in fatal Plasmodium falciparum malaria. Trop Med Int Health (2007) 1.50
Fatal Plasmodium falciparum malaria causes specific patterns of splenic architectural disorganization. Infect Immun (2005) 1.30
Histopathology of fatal respiratory distress caused by Plasmodium vivax malaria. Am J Trop Med Hyg (2009) 1.27
Orientia tsutsugamushi in human scrub typhus eschars shows tropism for dendritic cells and monocytes rather than endothelium. PLoS Negl Trop Dis (2012) 1.12
The clinical significance of cerebrospinal fluid levels of kynurenine pathway metabolites and lactate in severe malaria. J Infect Dis (2002) 1.03
Coma in fatal adult human malaria is not caused by cerebral oedema. Malar J (2011) 1.02
Metabolites of the kynurenine pathway of tryptophan metabolism in the cerebrospinal fluid of Malawian children with malaria. J Infect Dis (2003) 1.01
A quantitative ultrastructural study of the liver and the spleen in fatal falciparum malaria. Southeast Asian J Trop Med Public Health (2005) 0.99
Induction of the vascular endothelial growth factor pathway in the brain of adults with fatal falciparum malaria is a non-specific response to severe disease. Histopathology (2010) 0.93
Host vascular endothelial growth factor is trophic for Plasmodium falciparum-infected red blood cells. Asian Pac J Allergy Immunol (2008) 0.93
Urine cytology screening for polyoma virus infection following renal transplantation: the Oxford experience. J Clin Pathol (2006) 0.91
Plasmodium falciparum and the blood-brain barrier--contacts and consequences. J Infect Dis (2007) 0.88
A clinicopathological correlation of the expression of the angiopoietin-Tie-2 receptor pathway in the brain of adults with Plasmodium falciparum malaria. Malar J (2013) 0.87
An intradermal inoculation model of scrub typhus in Swiss CD-1 mice demonstrates more rapid dissemination of virulent strains of Orientia tsutsugamushi. PLoS One (2013) 0.87
Erythropoietin and its receptors in the brainstem of adults with fatal falciparum malaria. Malar J (2009) 0.87
Serial analysis of resected prostate cancer suggests up-regulation of type 1 IGF receptor with disease progression. BJU Int (2010) 0.87
Human chorionic gonadotropin-secreting clear cell renal cell carcinoma with paraneoplastic gynaecomastia. Scand J Urol Nephrol (2008) 0.86
Ultrastructural and real-time microscopic changes in P. falciparum-infected red blood cells following treatment with antimalarial drugs. Ultrastruct Pathol (2011) 0.86
Selfish spermatogonial selection: evidence from an immunohistochemical screen in testes of elderly men. PLoS One (2012) 0.85
Correlation of biomarkers for parasite burden and immune activation with acute kidney injury in severe falciparum malaria. Malar J (2014) 0.83
Laparoscopic high-intensity focused ultrasound for renal tumours: a proof of concept study. BJU Int (2010) 0.81
Cerebrospinal fluid levels of markers of brain parenchymal damage in Vietnamese adults with severe malaria. Trans R Soc Trop Med Hyg (2005) 0.80