Published in Genomics on May 02, 2006
BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress. Mol Cell (2004) 2.32
Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53. Cancer Cell (2012) 2.29
Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function. J Cell Biol (2002) 2.03
Trans-synaptic Eph receptor-ephrin signaling in hippocampal mossy fiber LTP. Science (2002) 1.77
Neutralizing antibody-resistant hepatitis C virus cell-to-cell transmission. J Virol (2010) 1.67
Evolutionarily conserved cytoprotection provided by Bax Inhibitor-1 homologs from animals, plants, and yeast. Gene (2003) 1.65
Inactivation of caspase-8 on mitochondria of Bcl-xL-expressing MCF7-Fas cells: role for the bifunctional apoptosis regulator protein. J Biol Chem (2001) 1.51
Small molecule scavenger receptor BI antagonists are potent HCV entry inhibitors. J Hepatol (2010) 1.37
Hepatitis C virus infection of neuroepithelioma cell lines. Gastroenterology (2010) 1.35
Pharmacological characterization of chemically synthesized monomeric phi29 pRNA nanoparticles for systemic delivery. Mol Ther (2011) 1.29
Nuclear hormone receptor NR4A2 is involved in cell transformation and apoptosis. Cancer Res (2004) 1.29
A recombinant sialidase fusion protein effectively inhibits human parainfluenza viral infection in vitro and in vivo. J Infect Dis (2010) 1.21
Pyrvinium targets the unfolded protein response to hypoglycemia and its anti-tumor activity is enhanced by combination therapy. PLoS One (2008) 1.20
Arginine methylation of RNA helicase a determines its subcellular localization. J Biol Chem (2004) 1.19
Prevalence of eye diseases and causes of visual impairment in school-aged children in Western China. J Epidemiol (2011) 1.17
Evaluation of ITX 5061, a scavenger receptor B1 antagonist: resistance selection and activity in combination with other hepatitis C virus antivirals. J Infect Dis (2012) 1.13
RNA helicase A interacts with nuclear factor kappaB p65 and functions as a transcriptional coactivator. Eur J Biochem (2004) 1.13
Cell surface CD4 interferes with the infectivity of HIV-1 particles released from T cells. J Biol Chem (2001) 1.13
Pre-clinical characterization of CX-4945, a potent and selective small molecule inhibitor of CK2 for the treatment of cancer. Mol Cell Biochem (2011) 1.12
Relative gene-silencing efficiencies of small interfering RNAs targeting sense and antisense transcripts from the same genetic locus. Nucleic Acids Res (2004) 1.10
Complement deposition and microglial activation in the outer retina in light-induced retinopathy: inhibition by a 5-HT1A agonist. Invest Ophthalmol Vis Sci (2011) 1.10
Identification of cellular cofactors for human immunodeficiency virus replication via a ribozyme-based genomics approach. J Virol (2004) 1.08
A plant-derived flavonoid inhibits entry of all HCV genotypes into human hepatocytes. Gastroenterology (2012) 1.06
CK2 inhibitor CX-4945 suppresses DNA repair response triggered by DNA-targeted anticancer drugs and augments efficacy: mechanistic rationale for drug combination therapy. Mol Cancer Ther (2012) 1.05
One-week 96-well soft agar growth assay for cancer target validation. Biotechniques (2004) 1.04
DAS181, a sialidase fusion protein, protects human airway epithelium against influenza virus infection: an in vitro pharmacodynamic analysis. J Antimicrob Chemother (2009) 1.04
Exon-level expression profiling of ocular tissues. Exp Eye Res (2013) 1.04
Characterization of the anti-apoptotic mechanism of Bcl-B. Biochem J (2003) 1.03
Subunit-specific roles of glycine-binding domains in activation of NR1/NR3 N-methyl-D-aspartate receptors. Mol Pharmacol (2006) 1.01
Safety and antiviral activity of the HCV entry inhibitor ITX5061 in treatment-naive HCV-infected adults: a randomized, double-blind, phase 1b study. J Infect Dis (2013) 0.99
Refractive status and prevalence of refractive errors in suburban school-age children. Int J Med Sci (2010) 0.99
The HIV-1 HLA-A2-SLYNTVATL is a help-independent CTL epitope. J Immunol (2004) 0.97
Structural and biochemical characterization of the therapeutic Anabaena variabilis phenylalanine ammonia lyase. J Mol Biol (2008) 0.95
RNA interference and potential applications. Curr Top Med Chem (2006) 0.94
Successful anti-scavenger receptor class B type I (SR-BI) monoclonal antibody therapy in humanized mice after challenge with HCV variants with in vitro resistance to SR-BI-targeting agents. Hepatology (2014) 0.93
Toxicity and intraocular properties of a novel long-acting anti-proliferative and anti-angiogenic compound IMS2186. Curr Eye Res (2008) 0.92
Functional interaction of Sam68 and heterogeneous nuclear ribonucleoprotein K. Oncogene (2002) 0.92
A more efficient RNAi inducible system for tight regulation of gene expression in mammalian cells and xenograft animals. RNA (2007) 0.92
Protein kinase CK2 modulates IL-6 expression in inflammatory breast cancer. Biochem Biophys Res Commun (2011) 0.90
Lgr5 expression as stem cell marker in human gastric gland and its relatedness with other putative cancer stem cell markers. Gene (2013) 0.89
Transduction of cell lines and primary cells by FIV-packaged HIV vectors. Mol Ther (2004) 0.88
Orphan G protein-coupled receptor GPR56 plays a role in cell transformation and tumorigenesis involving the cell adhesion pathway. Mol Cancer Ther (2007) 0.88
Rapid and quantitative assessment of cell quality, identity, and functionality for cell-based assays using real-time cellular analysis. J Biomol Screen (2011) 0.88
Clinical implications of CIP2A protein expression in breast cancer. Med Oncol (2013) 0.88
Discovery of ITX 4520: a highly potent orally bioavailable hepatitis C virus entry inhibitor. Bioorg Med Chem Lett (2012) 0.88
Biochemical characterization of genetic mutations of GPR56 in patients with bilateral frontoparietal polymicrogyria (BFPP). Biochem Biophys Res Commun (2007) 0.88
The intracellular II-III loops of Cav1.2 and Cav1.3 uncouple L-type voltage-gated Ca2+ channels from glucagon-like peptide-1 potentiation of insulin secretion in INS-1 cells via displacement from lipid rafts. J Pharmacol Exp Ther (2009) 0.86
A role for KH domain proteins (Sam68-like mammalian proteins and quaking proteins) in the post-transcriptional regulation of HIV replication. J Biol Chem (2001) 0.86
Comparisons of RNAi approaches for validation of human RNA helicase A as an essential factor in hepatitis C virus replication. J Virol Methods (2008) 0.85
Identification and characterization of NF-Y transcription factor families in Canola (Brassica napus L.). Planta (2013) 0.84
Oncolytic virotherapy as a personalized cancer vaccine. Int J Cancer (2008) 0.83
A new inducible RNAi xenograft model for assessing the staged tumor response to mTOR silencing. Exp Cell Res (2006) 0.83
Expression, purification, and renaturation of bone morphogenetic protein-2 from Escherichia coli. Protein Expr Purif (2005) 0.83
Mineralocorticoid receptor is involved in the regulation of genes responsible for hepatic glucose production. Biochem Biophys Res Commun (2006) 0.83
Discovery of highly potent small molecule Hepatitis C Virus entry inhibitors. Bioorg Med Chem Lett (2011) 0.82
Regulation of gap junction coupling in bovine ciliary epithelium. Am J Physiol Cell Physiol (2010) 0.81
Regulation of gene expression in response to brain injury: enhanced expression and alternative splicing of rat prosaposin (SGP-1) mRNA in injured brain. J Neurotrauma (2003) 0.81
Ribozyme technology for cancer gene target identification and validation. Adv Cancer Res (2007) 0.80
PHTS, a novel putative tumor suppressor, is involved in the transformation reversion of HeLaHF cells independently of the p53 pathway. Exp Cell Res (2006) 0.80
Generation of shRNA pool library: a revision of the biological technique from the viewpoint of chemistry. Chembiochem (2008) 0.80
Isoginkgetin enhances adiponectin secretion from differentiated adiposarcoma cells via a novel pathway involving AMP-activated protein kinase. J Endocrinol (2007) 0.80
ITX 5061 quantitation in human plasma with reverse phase liquid chromatography and mass spectrometry detection. Antivir Ther (2012) 0.79
Development of a detector for liquid chromatography based on aerosol chemiluminescence on porous alumina. Anal Chem (2005) 0.79
Screening of small-molecule compounds as inhibitors of HCV entry. Methods Mol Biol (2009) 0.79
Fusogenic oncolytic herpes simplex viruses as a potent and personalized cancer vaccine. Curr Pharm Biotechnol (2012) 0.78
A 96-well surrogate survival assay coupled with a special short interfering RNA vector for assessing cancer gene targets with enhanced signal/noise ratio and its utility in HTS for cancer therapeutic targets. Assay Drug Dev Technol (2005) 0.78