Published in Eur J Cancer on May 02, 2006
Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance. Cell Cycle (2009) 3.60
Drug-selected human lung cancer stem cells: cytokine network, tumorigenic and metastatic properties. PLoS One (2008) 3.36
Human prostate sphere-forming cells represent a subset of basal epithelial cells capable of glandular regeneration in vivo. Prostate (2010) 1.78
Resveratrol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition. PLoS One (2011) 1.67
Higher percentage of CD133+ cells is associated with poor prognosis in colon carcinoma patients with stage IIIB. J Transl Med (2009) 1.48
Recent advances in cancer stem/progenitor cell research: therapeutic implications for overcoming resistance to the most aggressive cancers. J Cell Mol Med (2007) 1.48
Drug-induced senescence generates chemoresistant stemlike cells with low reactive oxygen species. J Biol Chem (2011) 1.36
AFAP-110 is overexpressed in prostate cancer and contributes to tumorigenic growth by regulating focal contacts. J Clin Invest (2007) 1.30
Elimination of human lung cancer stem cells through targeting of the stem cell factor-c-kit autocrine signaling loop. Cancer Res (2009) 1.28
The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition. J Mol Signal (2010) 1.26
Oct4A is expressed by a subpopulation of prostate neuroendocrine cells. Prostate (2009) 1.25
Accumulating progenitor cells in the luminal epithelial cell layer are candidate tumor initiating cells in a Pten knockout mouse prostate cancer model. PLoS One (2009) 1.24
Loss of androgen receptor expression promotes a stem-like cell phenotype in prostate cancer through STAT3 signaling. Cancer Res (2013) 1.13
Tumor-initiating and -propagating cells: cells that we would like to identify and control. Neoplasia (2010) 1.11
TGF-beta and BMP7 interactions in tumour progression and bone metastasis. Clin Exp Metastasis (2007) 1.08
A simple mathematical model based on the cancer stem cell hypothesis suggests kinetic commonalities in solid tumor growth. PLoS One (2012) 1.04
What is the clinical value of cancer stem cell markers in gliomas? Int J Clin Exp Pathol (2013) 1.02
Hedgehog overexpression leads to the formation of prostate cancer stem cells with metastatic property irrespective of androgen receptor expression in the mouse model. J Biomed Sci (2011) 0.97
Identification of prostate-enriched proteins by in-depth proteomic analyses of expressed prostatic secretions in urine. J Proteome Res (2012) 0.97
Human prostate cancer harbors the stem cell properties of bone marrow mesenchymal stem cells. Clin Cancer Res (2011) 0.97
Identification, characterization, and biological relevance of prostate cancer stem cells from clinical specimens. Urol Oncol (2009) 0.94
Chemokines: key players in cancer progression and metastasis. Front Biosci (Schol Ed) (2011) 0.94
A miRNA signature of chemoresistant mesenchymal phenotype identifies novel molecular targets associated with advanced pancreatic cancer. PLoS One (2014) 0.93
Functions of normal and malignant prostatic stem/progenitor cells in tissue regeneration and cancer progression and novel targeting therapies. Endocr Rev (2008) 0.92
Prostate stem cells in the development of benign prostate hyperplasia and prostate cancer: emerging role and concepts. Biomed Res Int (2013) 0.87
Reprogramming murine telomerase rapidly inhibits the growth of mouse cancer cells in vitro and in vivo. Mol Cancer Ther (2010) 0.86
Pigment epithelium-derived factor and interleukin-6 control prostate neuroendocrine differentiation via feed-forward mechanism. J Urol (2008) 0.85
Prostate Cancer Stem Cells: Research Advances. Int J Mol Sci (2015) 0.84
A novel anticancer agent SNG1153 inhibits growth of lung cancer stem/progenitor cells. Oncotarget (2016) 0.83
Aberrant microRNAs expression in CD133⁺/CD326⁺ human lung adenocarcinoma initiating cells from A549. Mol Cells (2012) 0.83
Emerging putative biomarkers: the role of alpha 2 and 6 integrins in susceptibility, treatment, and prognosis. Prostate Cancer (2012) 0.83
Lung cancer stem cell: new insights on experimental models and preclinical data. J Oncol (2010) 0.80
Early human prostate adenocarcinomas harbor androgen-independent cancer cells. PLoS One (2013) 0.79
Novel therapies against aggressive and recurrent epithelial cancers by molecular targeting tumor- and metastasis-initiating cells and their progenies. Anticancer Agents Med Chem (2010) 0.79
Metformin and prostate cancer stem cells: a novel therapeutic target. Prostate Cancer Prostatic Dis (2015) 0.79
Role of BioResponse 3,3'-Diindolylmethane in the Treatment of Human Prostate Cancer: Clinical Experience. Med Princ Pract (2015) 0.77
Personalized Medicine Approaches in Prostate Cancer Employing Patient Derived 3D Organoids and Humanized Mice. Front Cell Dev Biol (2016) 0.75
Progress in the research on the mechanism of bone metastasis in lung cancer. Mol Clin Oncol (2016) 0.75
Characterization of reactive stroma in prostate cancer: involvement of growth factors, metalloproteinase matrix, sexual hormones receptors and prostatic stem cells. Int Braz J Urol (2015) 0.75
Pathogenesis of prostate cancer and hormone refractory prostate cancer. Indian J Urol (2007) 0.75
Inhibition of the PI3K/AKT/mTOR pathway activates autophagy and compensatory Ras/Raf/MEK/ERK signalling in prostate cancer. Oncotarget (2017) 0.75
Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res (2005) 13.89
CD133, a novel marker for human prostatic epithelial stem cells. J Cell Sci (2004) 4.76
Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions. Genome Biol (2008) 1.62
Monoallelic expression of TMPRSS2/ERG in prostate cancer stem cells. Nat Commun (2013) 1.57
Enhanced expression of vimentin in motile prostate cell lines and in poorly differentiated and metastatic prostate carcinoma. Prostate (2002) 1.52
JAK-STAT blockade inhibits tumor initiation and clonogenic recovery of prostate cancer stem-like cells. Cancer Res (2013) 1.19
Human epithelial basal cells are cells of origin of prostate cancer, independent of CD133 status. Stem Cells (2012) 1.19
Use of macrophages to target therapeutic adenovirus to human prostate tumors. Cancer Res (2011) 1.12
Androgen receptor signalling in prostate: effects of stromal factors on normal and cancer stem cells. Mol Cell Endocrinol (2008) 1.06
Regulation of protein kinase B activity by PTEN and SHIP2 in human prostate-derived cell lines. Cell Signal (2006) 1.04
A preclinical xenograft model of prostate cancer using human tumors. Nat Protoc (2013) 1.02
Cancer stem cells, models of study and implications of therapy resistance mechanisms. Adv Exp Med Biol (2011) 1.02
Prostate cancer stem cells: are they androgen-responsive? Mol Cell Endocrinol (2011) 0.94
Advanced prostate cancer--a case for adjuvant differentiation therapy. Nat Rev Urol (2012) 0.93
Differentiation of prostate epithelial cell cultures by matrigel/ stromal cell glandular reconstruction. In Vitro Cell Dev Biol Anim (2006) 0.89
Differential expression of neutral endopeptidase-24.11 (neprilysin) and endothelin-converting enzyme in human prostate cancer cell lines. Clin Sci (Lond) (2002) 0.88
Altered expression of neurotensin receptors is associated with the differentiation state of prostate cancer. Cancer Res (2010) 0.88
Dimerization of the human papillomavirus type 16 E2 N terminus results in DNA looping within the upstream regulatory region. J Virol (2008) 0.86
Prominin-1 (CD133) Expression in the Prostate and Prostate Cancer: A Marker for Quiescent Stem Cells. Adv Exp Med Biol (2013) 0.85
Regulation of the stem cell marker CD133 is independent of promoter hypermethylation in human epithelial differentiation and cancer. Mol Cancer (2011) 0.85
Retinoic acid and androgen receptors combine to achieve tissue specific control of human prostatic transglutaminase expression: a novel regulatory network with broader significance. Nucleic Acids Res (2012) 0.85
Primary prostate stromal cells modulate the morphology and migration of primary prostate epithelial cells in type 1 collagen gels. Cancer Res (2002) 0.84
Phenotypic effects of HPV-16 E2 protein expression in human keratinocytes. Virology (2010) 0.83
Development and limitations of lentivirus vectors as tools for tracking differentiation in prostate epithelial cells. Exp Cell Res (2010) 0.83
The calcium sensor STIM1 is regulated by androgens in prostate stromal cells. Prostate (2011) 0.82
Differential cytotoxic activity of a novel palladium-based compound on prostate cell lines, primary prostate epithelial cells and prostate stem cells. PLoS One (2013) 0.82
Seeding drug discovery: integrating telomerase cancer biology and cellular senescence to uncover new therapeutic opportunities in targeting cancer stem cells. Drug Discov Today (2007) 0.81
Baculoviruses as gene therapy vectors for human prostate cancer. J Invertebr Pathol (2011) 0.81
An internal polyadenylation signal substantially increases expression levels of lentivirus-delivered transgenes but has the potential to reduce viral titer in a promoter-dependent manner. Hum Gene Ther (2008) 0.81
Evaluating baculovirus as a vector for human prostate cancer gene therapy. PLoS One (2013) 0.80
Optimization of a synthetic beta-catenin-dependent promoter for tumor-specific cancer gene therapy. Mol Ther (2004) 0.79
Expression and localization of endothelin-converting enzyme-1 in human prostate cancer. Exp Biol Med (Maywood) (2006) 0.78
Preclinical evaluation of innate immunity to baculovirus gene therapy vectors in whole human blood. Mol Immunol (2009) 0.78
Prostate cancer: regeneration of interest in the prostate. Nat Rev Urol (2009) 0.76
Preclinical safety assessment of Ad[I/PPT-E1A], a novel oncolytic adenovirus for prostate cancer. Hum Gene Ther Clin Dev (2014) 0.76
A fusion at the root of prostate cancer. Asian J Androl (2013) 0.75
Coculture of prostate cancer cells. Methods Mol Med (2004) 0.75