A phase I clinical and pharmacokinetic study of the multi-drug resistance protein-1 (MRP-1) inhibitor sulindac, in combination with epirubicin in patients with advanced cancer.

PubWeight™: 0.90‹?›

🔗 View Article (PMID 16642371)

Published in Cancer Chemother Pharmacol on April 27, 2006

Authors

R O'Connor1, M O'Leary, J Ballot, C D Collins, P Kinsella, D E Mager, R D Arnold, L O'Driscoll, A Larkin, S Kennedy, D Fennelly, M Clynes, J Crown

Author Affiliations

1: The National Institute for Cellular Biotechnology, Dublin City University, Dublin, 9, Ireland. robert.oconnor@dcu.ie

Articles citing this

ABC transporters in cancer: more than just drug efflux pumps. Nat Rev Cancer (2010) 3.44

Targeting MDR in breast and lung cancer: discriminating its potential importance from the failure of drug resistance reversal studies. Drug Resist Updat (2012) 1.23

Resistance to paclitaxel in a cisplatin-resistant ovarian cancer cell line is mediated by P-glycoprotein. PLoS One (2012) 1.08

Small-molecule multidrug resistance-associated protein 1 inhibitor reversan increases the therapeutic index of chemotherapy in mouse models of neuroblastoma. Cancer Res (2009) 1.01

Anti-Inflammatory Agents for Cancer Therapy. Mol Cell Pharmacol (2009) 0.98

Tyrosine kinase inhibitors potentiate the cytotoxicity of MDR-substrate anticancer agents independent of growth factor receptor status in lung cancer cell lines. Invest New Drugs (2009) 0.93

Role of ABC transporters in cancer chemotherapy. Chin J Cancer (2012) 0.87

Cooperation between prokaryotic (Lde) and eukaryotic (MRP) efflux transporters in J774 macrophages infected with Listeria monocytogenes: studies with ciprofloxacin and moxifloxacin. Antimicrob Agents Chemother (2008) 0.85

Wnt-beta-catenin pathway signals metastasis-associated tumor cell phenotypes in triple negative breast cancers. Oncotarget (2016) 0.78

Synergistic cytotoxic effect of sulindac and pyrrolidine dithiocarbamate against ovarian cancer cells. Oncol Rep (2012) 0.75

Mechanisms of drug resistance in colon cancer and its therapeutic strategies. World J Gastroenterol (2016) 0.75

RAC1 GTP-ase signals wnt-beta-catenin pathway mediated integrin-directed metastasis-associated tumor cell phenotypes in triple negative breast cancers. Oncotarget (2016) 0.75

Chemotherapy Resistance Mechanisms in Advanced Skin Cancer. Oncol Rev (2017) 0.75

Sulindac sulfide selectively increases sensitivity of ABCC1 expressing tumor cells to doxorubicin and glutathione depletion. J Biomed Res (2015) 0.75

Articles by these authors

Initial sequencing and analysis of the human genome. Nature (2001) 212.86

A physical map of the human genome. Nature (2001) 12.39

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase. Genes Dev (2001) 5.12

Inactivation of the alpha-haemolysin gene of Staphylococcus aureus 8325-4 by site-directed mutagenesis and studies on the expression of its haemolysins. Microb Pathog (1986) 3.87

Isolation of porcine circovirus-like viruses from pigs with a wasting disease in the USA and Europe. J Vet Diagn Invest (1998) 3.18

Limbic-frontal circuitry in major depression: a path modeling metanalysis. Neuroimage (2004) 3.15

Caseload or workload? Scoring complexity of operative procedures as a means of analysing workload. BMJ (1990) 3.04

In vitro activity of N-formimidoyl thienamycin, moxalactam, and other new beta-lactam agents against Bacteroides fragilis: contribution of beta-lactamase to resistance. Antimicrob Agents Chemother (1981) 2.96

Characterization of novel circovirus DNAs associated with wasting syndromes in pigs. J Gen Virol (1998) 2.90

The effects of adherence to antidepressant treatment guidelines on relapse and recurrence of depression. Arch Gen Psychiatry (1998) 2.81

PMWS and porcine dermatitis nephropathy syndrome in Great Britain. Vet Rec (2000) 2.67

Closure of colostomy. Br J Surg (1971) 2.67

The taxanes: an update. Lancet (2000) 2.55

Sensitivity and specificity of PC20 and peak expiratory flow rate in cedar asthma. J Allergy Clin Immunol (1990) 2.37

Expression of a cloned Staphylococcus aureus alpha-hemolysin determinant in Bacillus subtilis and Staphylococcus aureus. Infect Immun (1983) 2.28

Ensemble asteroseismology of solar-type stars with the NASA Kepler mission. Science (2011) 2.28

Health service accreditation: report of a pilot programme for community hospitals. BMJ (1995) 2.25

Prospective randomized trial of docetaxel versus doxorubicin in patients with metastatic breast cancer. J Clin Oncol (1999) 2.19

NHS trusts and Jehovah's Witnesses. Lancet (1992) 2.14

Potency, continence and complication rates in 1,870 consecutive radical retropubic prostatectomies. J Urol (1999) 2.07

Attitudes to follow-up after uncomplicated surgery--hospital out-patients or general practitioner? Health Trends (1984) 2.06

Pathological response following long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer. Histopathology (2005) 2.02

Reproduction of lesions of postweaning multisystemic wasting syndrome in gnotobiotic piglets. J Vet Diagn Invest (1999) 1.98

Platelet derived growth factor and fibroblast growth factor basic levels in the vitreous of patients with vitreoretinal disorders. Br J Ophthalmol (1998) 1.95

Consolidation chemoradiotherapy and autologous bone marrow transplantation versus continued chemotherapy for metastatic neuroblastoma: a report of two concurrent Children's Cancer Group studies. J Clin Oncol (1996) 1.94

Pathological, immunohistochemical, and in-situ hybridization studies of natural cases of postweaning multisystemic wasting syndrome (PMWS) in pigs. J Comp Pathol (1999) 1.91

Bulimia nervosa in a Canadian community sample: prevalence and comparison of subgroups. Am J Psychiatry (1995) 1.90

Experimental reproduction of severe wasting disease by co-infection of pigs with porcine circovirus and porcine parvovirus. J Comp Pathol (1999) 1.88

p38 MAPK and NF-kappa B collaborate to induce interleukin-6 gene expression and release. Evidence for a cytoprotective autocrine signaling pathway in a cardiac myocyte model system. J Biol Chem (2000) 1.88

Effects of dosage, peak and trough concentrations in serum, protein binding, and bactericidal rate on efficacy of teicoplanin in a rabbit model of endocarditis. Antimicrob Agents Chemother (1990) 1.85

Epidermal growth factor receptor as a potential therapeutic target in triple-negative breast cancer. Ann Oncol (2009) 1.83

The 2000 canine distemper epidemic in Caspian seals (Phoca caspica): pathology and analysis of contributory factors. Vet Pathol (2006) 1.82

Central venous catheters-time for a change?. If you put them in properly you don't need to change them routinely. BMJ (1998) 1.82

Viral wasting syndrome of swine: experimental reproduction of postweaning multisystemic wasting syndrome in gnotobiotic swine by coinfection with porcine circovirus 2 and porcine parvovirus. Vet Pathol (2000) 1.82

Use of lower prostate specific antigen cutoffs for prostate cancer screening in black and white men. J Urol (1998) 1.80

Perioperative management of a case of severe peripartum cardiomyopathy. Anaesth Intensive Care (1992) 1.78

Proof of the pudding. CASPE's patient satisfaction system. Health Serv J (1989) 1.75

Morbillivirus infections in aquatic mammals. J Comp Pathol (1998) 1.74

Cimetidine for peptic ulcer in patients with arthritis. Ann Rheum Dis (1980) 1.72

Impact of first-line vs second-line antibiotics for the treatment of acute uncomplicated sinusitis. JAMA (2001) 1.71

Experimental infection of colostrum deprived piglets with porcine circovirus 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) potentiates PCV2 replication. Arch Virol (2000) 1.71

A prospective randomized trial comparing 6 versus 12 prostate biopsy cores: impact on cancer detection. J Urol (2000) 1.69

Fragile X-associated tremor/ataxia syndrome presenting in a woman after chemotherapy. Neurology (2005) 1.63

Morphology of peripheral airways in current smokers and ex-smokers. Am Rev Respir Dis (1983) 1.63

Morbillivirus in dolphins. Nature (1990) 1.61

Metabolic syndrome: a closer look at the growing epidemic and its associated pathologies. Obes Rev (2014) 1.59

Peritoneal involvement in stage II colon cancer. Am J Clin Pathol (2003) 1.59

Urological and colorectal complications following surgery for rectovaginal endometriosis. BJOG (2007) 1.58

Binding affinity for penicillin-binding protein 2a correlates with in vivo activity of beta-lactam antibiotics against methicillin-resistant Staphylococcus aureus. J Infect Dis (1990) 1.57

Prognostic importance of survivin in breast cancer. Br J Cancer (2003) 1.56

Delay in the diagnosis of endometriosis: a survey of women from the USA and the UK. Hum Reprod (1996) 1.55

Comparing assessments of DSM-IV substance dependence disorders using CIDI-SAM and SCAN. Drug Alcohol Depend (1996) 1.54

Byler-like familial cholestasis in an extended kindred. Arch Dis Child (1996) 1.53

Depression in self-harm patients. Br J Psychiatry (1989) 1.52

Do gastrointestinal symptoms vary with the menstrual cycle? Br J Obstet Gynaecol (1998) 1.51

The effect of cyclosporine on the use of hospital resources for kidney transplantation. N Engl J Med (1989) 1.49

Does neostigmine increase gastric emptying in the critically ill?--results of a pilot study. Crit Care Resusc (2003) 1.47

Respiratory mucosal permeability in asthma. Am Rev Respir Dis (1983) 1.46

Intradermal radioisotope injection optimises sentinel lymph node identification in breast cancer. Eur J Surg Oncol (2003) 1.46

Changes in body mass index and prevalence of overweight in survivors of childhood acute lymphoblastic leukemia: role of cranial irradiation. Med Pediatr Oncol (2000) 1.45

MiRNA-29a regulates the expression of numerous proteins and reduces the invasiveness and proliferation of human carcinoma cell lines. Eur J Cancer (2009) 1.44

Pathologic and immunocytochemical studies of morbillivirus infection in striped dolphins (Stenella coeruleoalba). Vet Pathol (1992) 1.44

The North Dublin randomized controlled trial of structured diabetes shared care. Fam Pract (2004) 1.44

Localization of a gene (MCUL1) for multiple cutaneous leiomyomata and uterine fibroids to chromosome 1q42.3-q43. Am J Hum Genet (2001) 1.42

Association of HLA type with pseudoexfoliation of the lens capsule. Br J Ophthalmol (1996) 1.41

Isolation and characterisation of circoviruses from pigs with wasting syndromes in Spain, Denmark and Northern Ireland. Vet Microbiol (1999) 1.40

Fibre mapping--a case study. Sci Justice (2004) 1.40

Atenolol in essential hypertension during pregnancy. BMJ (1990) 1.39

Development of clinical audit. Br J Hosp Med (1989) 1.39

A measure of independence. Teaching home blood pressure monitoring. Prof Nurse (1991) 1.39

Leaching of chromated copper arsenate wood preservatives: a review. Environ Pollut (2001) 1.38

Should amenorrhoea be necessary for the diagnosis of anorexia nervosa? Evidence from a Canadian community sample. Br J Psychiatry (1996) 1.38

Survivin expression in breast cancer predicts clinical outcome and is associated with HER2, VEGF, urokinase plasminogen activator and PAI-1. Ann Oncol (2006) 1.37

Isolation of Chlamydia trachomatis from the lower respiratory tract of adults. Lancet (1980) 1.37

Novel porcine circoviruses from pigs with wasting disease syndromes. Vet Rec (1998) 1.35

Stress fractures of the lower limb in patients with rheumatoid arthritis. J Bone Joint Surg Br (1981) 1.35

Postmortem diagnosis of morbillivirus infection in bottlenose dolphins (Tursiops truncatus) in the Atlantic and Gulf of Mexico epizootics by polymerase chain reaction-based assay. J Wildl Dis (1995) 1.34

Morbilliviral disease in Atlantic bottlenose dolphins (Tursiops truncatus) from the 1987-1988 epizootic. J Wildl Dis (1994) 1.34

Novel role for RNA-binding protein CUGBP2 in mammalian RNA editing. CUGBP2 modulates C to U editing of apolipoprotein B mRNA by interacting with apobec-1 and ACF, the apobec-1 complementation factor. J Biol Chem (2001) 1.32

Stress-induced modulation of the immune response to recombinant hepatitis B vaccine. Psychosom Med (1992) 1.31

Force in the anal canal and anal continence. Gut (1967) 1.30

Chest complications after upper abdominal surgery: their anticipation and prevention. Br Med J (1968) 1.28

Auditory brainstem implant: II. Postsurgical issues and performance. Otolaryngol Head Neck Surg (1993) 1.27

Development of novel cell surface CD34-targeted recombinant adenoassociated virus vectors for gene therapy. Hum Gene Ther (1998) 1.27

The association between body mass and health care expenditures. Clin Ther (1997) 1.25

Physical and cognitive performance and burden of anticholinergics, sedatives, and ACE inhibitors in older women. Clin Pharmacol Ther (2007) 1.25

HER-2 signaling and inhibition in breast cancer. Curr Cancer Drug Targets (2009) 1.25

Porcine circovirus-2 and concurrent infections in the field. Vet Microbiol (2004) 1.24

Identification of GRY-RBP as an apolipoprotein B RNA-binding protein that interacts with both apobec-1 and apobec-1 complementation factor to modulate C to U editing. J Biol Chem (2000) 1.24

Morbillivirus infections in aquatic mammals: a brief overview. J Vet Med A Physiol Pathol Clin Med (2005) 1.23

Src: a potential target for the treatment of triple-negative breast cancer. Ann Oncol (2011) 1.23

Basal electrical activity in the anal canal in man. Gut (1968) 1.22

Canine distemper virus in a Caspian seal. Vet Rec (1998) 1.21

The detection of small airways disease. Am Rev Respir Dis (1984) 1.20

Identification of a survival-promoting peptide in medium conditioned by oxidatively stressed cell lines of nervous system origin. J Neurosci (1998) 1.20

Outcome of patients with cedar asthma with continuous exposure. Am Rev Respir Dis (1990) 1.19

Final height after treatment for childhood acute lymphoblastic leukemia: comparison of no cranial irradiation with 1800 and 2400 centigrays of cranial irradiation. J Pediatr (1993) 1.19

A simplified tumor regression grade correlates with survival in locally advanced rectal carcinoma treated with neoadjuvant chemoradiotherapy. Ann Surg Oncol (2008) 1.18