Published in FEBS J on May 01, 2006
Amitozyn impairs chromosome segregation and induces apoptosis via mitotic checkpoint activation. PLoS One (2013) 1.39
Alkaloids isolated from natural herbs as the anticancer agents. Evid Based Complement Alternat Med (2012) 1.13
Comparison of small molecule inhibitors of the bacterial cell division protein FtsZ and identification of a reliable cross-species inhibitor. ACS Chem Biol (2012) 1.04
Sanguinarine suppresses prostate tumor growth and inhibits survivin expression. Genes Cancer (2010) 1.01
A fluorescence polarization binding assay to identify inhibitors of flavin-dependent monooxygenases. Anal Biochem (2012) 0.76
Bloodroot (Sanguinaria canadensis L., Papaveraceae) Enhances Proliferation and Cytokine Production by Human Peripheral Blood Mononuclear Cells in an In Vitro Model. J Herbs Spices Med Plants (2009) 0.76
Sanguinaria canadensis: Traditional Medicine, Phytochemical Composition, Biological Activities and Current Uses. Int J Mol Sci (2016) 0.75
A Review of Black Salve: Cancer Specificity, Cure, and Cosmesis. Evid Based Complement Alternat Med (2017) 0.75
Anti-mitotic activity of colchicine and the structural basis for its interaction with tubulin. Med Res Rev (2008) 1.67
Promoting assembly and bundling of FtsZ as a strategy to inhibit bacterial cell division: a new approach for developing novel antibacterial drugs. Biochem J (2009) 1.64
Curcumin inhibits FtsZ assembly: an attractive mechanism for its antibacterial activity. Biochem J (2008) 1.45
Minor alteration of microtubule dynamics causes loss of tension across kinetochore pairs and activates the spindle checkpoint. J Biol Chem (2002) 1.44
Brominated derivatives of noscapine are potent microtubule-interfering agents that perturb mitosis and inhibit cell proliferation. Mol Pharmacol (2003) 1.41
Totarol inhibits bacterial cytokinesis by perturbing the assembly dynamics of FtsZ. Biochemistry (2007) 1.38
Anticancer and antimicrobial metallopharmaceutical agents based on palladium, gold, and silver N-heterocyclic carbene complexes. J Am Chem Soc (2007) 1.36
Sanguinarine blocks cytokinesis in bacteria by inhibiting FtsZ assembly and bundling. Biochemistry (2005) 1.31
A membrane protein, EzrA, regulates assembly dynamics of FtsZ by interacting with the C-terminal tail of FtsZ. Biochemistry (2007) 1.23
Paclitaxel-resistant human ovarian cancer cells undergo c-Jun NH2-terminal kinase-mediated apoptosis in response to noscapine. J Biol Chem (2002) 1.22
Dietary antioxidant curcumin inhibits microtubule assembly through tubulin binding. FEBS J (2006) 1.18
SepF increases the assembly and bundling of FtsZ polymers and stabilizes FtsZ protofilaments by binding along its length. J Biol Chem (2008) 1.17
Targeting FtsZ for antibacterial therapy: a promising avenue. Expert Opin Ther Targets (2009) 1.16
Synthesis of microtubule-interfering halogenated noscapine analogs that perturb mitosis in cancer cells followed by cell death. Biochem Pharmacol (2006) 1.14
Development of a novel nitro-derivative of noscapine for the potential treatment of drug-resistant ovarian cancer and T-cell lymphoma. Mol Pharmacol (2006) 1.11
Rational design of the microtubule-targeting anti-breast cancer drug EM015. Cancer Res (2006) 1.11
Dicoumarol: a unique microtubule stabilizing natural product that is synergistic with Taxol. Cancer Res (2003) 1.10
Antimitotic antifungal compound benomyl inhibits brain microtubule polymerization and dynamics and cancer cell proliferation at mitosis, by binding to a novel site in tubulin. Biochemistry (2004) 1.08
Microtubule assembly dynamics: an attractive target for anticancer drugs. IUBMB Life (2008) 1.08
Griseofulvin stabilizes microtubule dynamics, activates p53 and inhibits the proliferation of MCF-7 cells synergistically with vinblastine. BMC Cancer (2010) 1.06
Perturbation of microtubule polymerization by quercetin through tubulin binding: a novel mechanism of its antiproliferative activity. Biochemistry (2002) 1.05
2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules. Mol Cancer Ther (2006) 1.02
Antimitotic sulfonamides inhibit microtubule assembly dynamics and cancer cell proliferation. Biochemistry (2006) 1.01
Glutamate-induced assembly of bacterial cell division protein FtsZ. J Biol Chem (2002) 0.98
Kinetic stabilization of microtubule dynamics by estramustine is associated with tubulin acetylation, spindle abnormalities, and mitotic arrest. Cancer Res (2008) 0.97
2,3-Disubstituted-1,4-naphthoquinones, 12H-benzo[b]phenothiazine-6,11-diones and related compounds: synthesis and biological evaluation as potential antiproliferative and antifungal agents. Eur J Med Chem (2008) 0.95
Curcumin suppresses the dynamic instability of microtubules, activates the mitotic checkpoint and induces apoptosis in MCF-7 cells. FEBS J (2010) 0.95
Rotenone inhibits mammalian cell proliferation by inhibiting microtubule assembly through tubulin binding. FEBS J (2007) 0.94
Synthesis and anticancer activity studies of alpha-aminoalkylated conjugated nitroalkenes. Org Biomol Chem (2006) 0.94
Mica surface promotes the assembly of cytoskeletal proteins. Langmuir (2009) 0.92
Kinetic stabilization of microtubule dynamic instability by benomyl increases the nuclear transport of p53. Biochem Pharmacol (2008) 0.92
Detection of an intermediate during unfolding of bacterial cell division protein FtsZ: loss of functional properties precedes the global unfolding of FtsZ. J Biol Chem (2003) 0.89
Inhibition of HDAC6 deacetylase activity increases its binding with microtubules and suppresses microtubule dynamic instability in MCF-7 cells. J Biol Chem (2013) 0.87
Ruthenium red-induced bundling of bacterial cell division protein, FtsZ. J Biol Chem (2004) 0.87
Curcumin recognizes a unique binding site of tubulin. J Med Chem (2011) 0.87
Probing the binding site of curcumin in Escherichia coli and Bacillus subtilis FtsZ--a structural insight to unveil antibacterial activity of curcumin. Eur J Med Chem (2010) 0.87
MAP2 prevents protein aggregation and facilitates reactivation of unfolded enzymes. Eur J Biochem (2004) 0.86
Kinetic stabilization of microtubule dynamics by indanocine perturbs EB1 localization, induces defects in cell polarity and inhibits migration of MDA-MB-231 cells. Biochem Pharmacol (2012) 0.86
Multiple-probe analysis of folding and unfolding pathways of human serum albumin. Evidence for a framework mechanism of folding. Eur J Biochem (2004) 0.85
Dynein light chain 1 (LC8) association enhances microtubule stability and promotes microtubule bundling. J Biol Chem (2012) 0.85
FtsZ inhibition: a promising approach for antistaphylococcal therapy. Drug News Perspect (2010) 0.84
An antitubulin agent BCFMT inhibits proliferation of cancer cells and induces cell death by inhibiting microtubule dynamics. PLoS One (2012) 0.84
Differential assembly properties of Escherichia coli FtsZ and Mycobacterium tuberculosis FtsZ: an analysis using divalent calcium. J Biochem (2009) 0.84
A synthetic dolastatin 10 analogue suppresses microtubule dynamics, inhibits cell proliferation, and induces apoptotic cell death. J Med Chem (2013) 0.83
An analysis of FtsZ assembly using small angle X-ray scattering and electron microscopy. Langmuir (2009) 0.82
Discrimination of ligands with different flexibilities resulting from the plasticity of the binding site in tubulin. Biochemistry (2012) 0.82
A rhodanine derivative CCR-11 inhibits bacterial proliferation by inhibiting the assembly and GTPase activity of FtsZ. Biochemistry (2012) 0.82
Fluorescence spectroscopic methods to analyze drug-tubulin interactions. Methods Cell Biol (2010) 0.82
CXI-benzo-84 reversibly binds to tubulin at colchicine site and induces apoptosis in cancer cells. Biochem Pharmacol (2013) 0.82
Cysteine 155 plays an important role in the assembly of Mycobacterium tuberculosis FtsZ. Protein Sci (2008) 0.81
Plumbagin inhibits cytokinesis in Bacillus subtilis by inhibiting FtsZ assembly--a mechanistic study of its antibacterial activity. FEBS J (2013) 0.81
Ansamitocin P3 depolymerizes microtubules and induces apoptosis by binding to tubulin at the vinblastine site. PLoS One (2013) 0.81
Cationic lipid enhances assembly of bacterial cell division protein FtsZ: a possible role of bacterial membrane in FtsZ assembly dynamics. Int J Biol Macromol (2011) 0.81
Unfolding pathways of human serum albumin: evidence for sequential unfolding and folding of its three domains. Int J Biol Macromol (2005) 0.81
E93R substitution of Escherichia coli FtsZ induces bundling of protofilaments, reduces GTPase activity, and impairs bacterial cytokinesis. J Biol Chem (2010) 0.80
CIL-102 binds to tubulin at colchicine binding site and triggers apoptosis in MCF-7 cells by inducing monopolar and multinucleated cells. Biochem Pharmacol (2012) 0.80
ZipA binds to FtsZ with high affinity and enhances the stability of FtsZ protofilaments. PLoS One (2011) 0.80
Deuterium oxide promotes assembly and bundling of FtsZ protofilaments. Proteins (2005) 0.80
GTP regulates the interaction between MciZ and FtsZ: a possible role of MciZ in bacterial cell division. Biochemistry (2012) 0.80
Pyrene excimer fluorescence of yeast alcohol dehydrogenase: a sensitive probe to investigate ligand binding and unfolding pathway of the enzyme. Photochem Photobiol (2006) 0.80
Benomyl and colchicine synergistically inhibit cell proliferation and mitosis: evidence of distinct binding sites for these agents in tubulin. Biochemistry (2008) 0.80
SB-RA-2001 inhibits bacterial proliferation by targeting FtsZ assembly. Biochemistry (2014) 0.80
A natural osmolyte trimethylamine N-oxide promotes assembly and bundling of the bacterial cell division protein, FtsZ and counteracts the denaturing effects of urea. FEBS J (2005) 0.80
Spatial relationship between the prodan site, Trp-214, and Cys-34 residues in human serum albumin and loss of structure through incremental unfolding. Biochemistry (2002) 0.79
Synthesis and evaluation of alpha-hydroxymethylated conjugated nitroalkenes for their anticancer activity: inhibition of cell proliferation by targeting microtubules. Bioorg Med Chem (2006) 0.79
Resveratrol inhibits type II phosphatidylinositol 4-kinase: a key component in pathways of phosphoinositide turn over. Biochem Pharmacol (2005) 0.79
Acid-induced loss of functional properties of bacterial cell division protein FtsZ: evidence for an alternative conformation at acidic pH. Proteins (2007) 0.78
The Morita-Baylis-Hillman adducts of beta-aryl nitroethylenes with other activated alkenes: synthesis and anticancer activity studies. Chem Commun (Camb) (2005) 0.78
Microtubules as antifungal and antiparasitic drug targets. Expert Opin Ther Pat (2011) 0.77
Cd2+ complex of a triazole-based calix[4]arene conjugate as a selective fluorescent chemosensor for Cys. Anal Chem (2012) 0.77
Proteomics analyses of Bacillus subtilis after treatment with plumbagin, a plant-derived naphthoquinone. OMICS (2015) 0.77
Large-bite bis(phosphite) ligand containing mesocyclic thioether moieties: synthesis, reactivity, group 11 (Cu(I), Au(I)) metal complexes and anticancer activity studies on a human cervical cancer (HeLa) cell line. Dalton Trans (2008) 0.77
Water-soluble cyclodiphosphazanes: synthesis, gold(I) metal complexes and their in vitro antitumor studies. Dalton Trans (2008) 0.77
Effects of pH and ionic strength on the assembly and bundling of FtsZ protofilaments: a possible role of electrostatic interactions in the bundling of protofilaments. Int J Biol Macromol (2006) 0.77
Pyrophosphate sensing by a fluorescent Zn2+ bound triazole linked imino-thiophenyl conjugate of calix[4]arene in HEPES buffer medium: spectroscopy, microscopy, and cellular studies. Anal Chem (2012) 0.77
Megacell phenotype and its relation to metabolic alterations in transketolase deficient strain of Bacillus pumilus. Biotechnol Bioeng (2009) 0.77
Dinuclear copper(I) complexes containing cyclodiphosphazane derivatives and pyridyl ligands: synthesis, structural studies, and antiproliferative activity toward human cervical and breast cancer cells. Inorg Chem (2010) 0.77
The centrosome: a prospective entrant in cancer therapy. Expert Opin Ther Targets (2015) 0.76
Assembly of Bacillus subtilis FtsA: effects of pH, ionic strength and nucleotides on FtsA assembly. Int J Biol Macromol (2012) 0.75
Antimicrobial peptide CRAMP (16-33) stalls bacterial cytokinesis by inhibiting FtsZ assembly. Biochemistry (2014) 0.75
Understanding FtsZ assembly: cues from the behavior of its N- and C-terminal domains. Biochemistry (2013) 0.75
Correction: Comprehensive Analysis of Temporal Alterations in Cellular Proteome of Bacillus subtilis under Curcumin Treatment. PLoS One (2015) 0.75
Imino-phenolic-pyridyl conjugates of calix[4]arene (L1 and L2) as primary fluorescence switch-on sensors for Zn2+ in solution and in HeLa cells and the recognition of pyrophosphate and ATP by [ZnL2]. Inorg Chem (2012) 0.75
HMBA depolymerizes microtubules, activates mitotic checkpoints and induces mitotic block in MCF-7 cells by binding at the colchicine site in tubulin. Biochem Pharmacol (2010) 0.75
History-dependent depolymerization of actin filaments. Biochemistry (2012) 0.75
Corrigendum to "HMBA depolymerizes microtubules, activates mitotic checkpoints and induces mitotic block in MCF-7 cells by binding at the colchicine site in tubulin" [Biochem. Pharmacol. 80 (2010) 50-61]. Biochem Pharmacol (2010) 0.75
Dinuclear Cu(I) complexes of pyridyl-diazadiphosphetidines and aminobis(phosphonite) ligands: synthesis, structural studies and antiproliferative activity towards human cervical, colon carcinoma and breast cancer cells. Dalton Trans (2014) 0.75
Sanguinarine suppresses IgE induced inflammatory responses through inhibition of type II PtdIns 4-kinase(s). Arch Biochem Biophys (2013) 0.75
A Zn2+ specific triazole based calix[4]arene conjugate (L) as a fluorescence sensor for histidine and cysteine in HEPES buffer milieu. Analyst (2012) 0.75