PubRank

Taha Merghoub

Author PubWeight™ 74.51‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts. J Exp Med 2010 4.90
2 Role of the proto-oncogene Pokemon in cellular transformation and ARF repression. Nature 2005 3.75
3 Relief of profound feedback inhibition of mitogenic signaling by RAF inhibitors attenuates their activity in BRAFV600E melanomas. Cancer Cell 2012 3.37
4 Regulation of B versus T lymphoid lineage fate decision by the proto-oncogene LRF. Science 2007 2.92
5 Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses. Cell 2015 2.60
6 Monocytic CCR2(+) myeloid-derived suppressor cells promote immune escape by limiting activated CD8 T-cell infiltration into the tumor microenvironment. Cancer Res 2011 2.20
7 Progression of RAS-mutant leukemia during RAF inhibitor treatment. N Engl J Med 2012 2.19
8 Cyclophosphamide enhances immunity by modulating the balance of dendritic cell subsets in lymphoid organs. Blood 2010 1.77
9 Agonist anti-GITR monoclonal antibody induces melanoma tumor immunity in mice by altering regulatory T cell stability and intra-tumor accumulation. PLoS One 2010 1.69
10 OX40 engagement and chemotherapy combination provides potent antitumor immunity with concomitant regulatory T cell apoptosis. J Exp Med 2009 1.63
11 Optimization of a self antigen for presentation of multiple epitopes in cancer immunity. J Clin Invest 2006 1.59
12 Agonist anti-GITR antibody enhances vaccine-induced CD8(+) T-cell responses and tumor immunity. Cancer Res 2006 1.57
13 Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence. Cancer Res 2014 1.55
14 Plzf mediates transcriptional repression of HoxD gene expression through chromatin remodeling. Dev Cell 2002 1.52
15 Self-antigen-specific CD8+ T cell precursor frequency determines the quality of the antitumor immune response. J Exp Med 2009 1.47
16 LRF is an essential downstream target of GATA1 in erythroid development and regulates BIM-dependent apoptosis. Dev Cell 2009 1.39
17 Induction of tumoricidal function in CD4+ T cells is associated with concomitant memory and terminally differentiated phenotype. J Exp Med 2012 1.32
18 Maternally transmitted severe glucose 6-phosphate dehydrogenase deficiency is an embryonic lethal. EMBO J 2002 1.30
19 Efficacy of intermittent combined RAF and MEK inhibition in a patient with concurrent BRAF- and NRAS-mutant malignancies. Cancer Discov 2014 1.25
20 Vaccinia virus subverts a mitochondrial antiviral signaling protein-dependent innate immune response in keratinocytes through its double-stranded RNA binding protein, E3. J Virol 2008 1.16
21 The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease. J Clin Invest 2009 1.11
22 Mutations of the PML tumor suppressor gene in acute promyelocytic leukemia. Blood 2003 1.10
23 Disruption of PLZP in mice leads to increased T-lymphocyte proliferation, cytokine production, and altered hematopoietic stem cell homeostasis. Mol Cell Biol 2004 1.07
24 T cells translate individual, quantal activation into collective, analog cytokine responses via time-integrated feedbacks. Elife 2014 1.02
25 Alphavirus replicon particles expressing TRP-2 provide potent therapeutic effect on melanoma through activation of humoral and cellular immunity. PLoS One 2010 0.99
26 Myxoma virus induces type I interferon production in murine plasmacytoid dendritic cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-dependent pathway. J Virol 2011 0.89
27 Detection of intra-tumor self antigen recognition during melanoma tumor progression in mice using advanced multimode confocal/two photon microscope. PLoS One 2011 0.88
28 Improved tumor immunity using anti-tyrosinase related protein-1 monoclonal antibody combined with DNA vaccines in murine melanoma. Cancer Res 2008 0.86
29 Mechanisms of immunization against cancer using chimeric antigens. Mol Ther 2008 0.85
30 Immune rejection of mouse tumors expressing mutated self. Cancer Res 2009 0.84
31 EWS-FLI-1-targeted cytotoxic T-cell killing of multiple tumor types belonging to the Ewing sarcoma family of tumors. Clin Cancer Res 2012 0.84
32 Combination of epitope-optimized DNA vaccination and passive infusion of monoclonal antibody against HER2/neu leads to breast tumor regression in mice. Vaccine 2011 0.83
33 Innate immune response of human plasmacytoid dendritic cells to poxvirus infection is subverted by vaccinia E3 via its Z-DNA/RNA binding domain. PLoS One 2012 0.82
34 Anaphylaxis caused by repetitive doses of a GITR agonist monoclonal antibody in mice. Blood 2014 0.82
35 Atypical t(15;17)(q13;q12) in a patient with all-trans retinoic acid refractory secondary acute promyelocytic leukemia: a case report and review of the literature. Cancer Genet Cytogenet 2002 0.81
36 Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses. Cell 2016 0.80
37 Combination of alphavirus replicon particle-based vaccination with immunomodulatory antibodies: therapeutic activity in the B16 melanoma mouse model and immune correlates. Cancer Immunol Res 2014 0.80
38 Myeloid-derived suppressor sells and the efficacy of CD8(+) T-cell immunotherapy. Oncoimmunology 2013 0.79
39 Development of effective vaccines for old mice in a tumor model. Vaccine 2008 0.77
40 Protein Expression Analysis of Melanocyte Differentiation Antigen TRP-2. Am J Dermatopathol 2016 0.75
41 Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses. Cell 2017 0.75