W Kreutner

Author PubWeight™ 50.61‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Inhibitory effect of the TRFK-5 anti-IL-5 antibody in a guinea pig model of asthma. Am Rev Respir Dis 1993 1.73
2 Characterization of a murine model of allergic pulmonary inflammation. Int Arch Allergy Immunol 1994 1.66
3 Inhibition of cytokine generation and mediator release by human basophils treated with desloratadine. Clin Exp Allergy 2001 1.63
4 Effects of an antibody to interleukin-5 in a monkey model of asthma. Am J Respir Crit Care Med 1995 1.40
5 Mast cells modulate allergic pulmonary eosinophilia in mice. Am J Respir Cell Mol Biol 1995 1.32
6 Antitussive effects of GABAB agonists in the cat and guinea-pig. Br J Pharmacol 1993 1.22
7 Cardiotoxic and drug interaction profile of the second generation antihistamines ebastine and terfenadine in an experimental animal model of torsade de pointes. Arzneimittelforschung 1996 1.22
8 Involvement of IL-5 in a murine model of allergic pulmonary inflammation: prophylactic and therapeutic effect of an anti-IL-5 antibody. Am J Respir Cell Mol Biol 1995 1.18
9 Effect of anti-mIL-9 antibody on the development of pulmonary inflammation and airway hyperresponsiveness in allergic mice. Am J Respir Cell Mol Biol 2001 1.16
10 Dependence on insulin of the apparent hydrocortisone activation of hepatic glycogen synthetase. Proc Natl Acad Sci U S A 1967 1.12
11 Peripheral and central sites of action of GABA-B agonists to inhibit the cough reflex in the cat and guinea pig. Br J Pharmacol 1994 1.11
12 Prejunctional GABA-B inhibition of cholinergic, neurally-mediated airway contractions in guinea-pigs. Pulm Pharmacol 1991 1.10
13 Comparative analysis of the cardiotoxicity proclivities of second generation antihistamines in an experimental model predictive of adverse clinical ECG effects. Arzneimittelforschung 1996 1.06
14 Role of nitric oxide on eosinophilic lung inflammation in allergic mice. Am J Respir Cell Mol Biol 1997 1.04
15 Interleukin-5 modulates eosinophil accumulation in allergic guinea pig lung. Am Rev Respir Dis 1992 1.03
16 Effect of Sch 55700, a humanized monoclonal antibody to human interleukin-5, on eosinophilic responses and bronchial hyperreactivity. Arzneimittelforschung 1999 0.97
17 Effects of chronic anti-interleukin-5 monoclonal antibody treatment in a murine model of pulmonary inflammation. Am J Respir Cell Mol Biol 1999 0.97
18 Inhibition of pulmonary eosinophilia and airway hyperresponsiveness in allergic mice by rolipram: involvement of endogenously released corticosterone and catecholamines. Br J Pharmacol 2000 0.91
19 Evaluation of the CNS properties of SCH 29851, a potential non-sedating antihistamine. Agents Actions 1984 0.90
20 Anaphylactic challenge causes eosinophil accumulation in bronchoalveolar lavage fluid of guinea pigs. Modulation by betamethasone, phenidone, indomethacin, WEB 2086, and a novel antiallergy agent, SCH 37224. Am Rev Respir Dis 1990 0.90
21 The pharmacology of SCH 50911: a novel, orally-active GABA-beta receptor antagonist. J Pharmacol Exp Ther 1995 0.89
22 Eosinophils retain their granule major basic protein in a murine model of allergic pulmonary inflammation. Am J Respir Cell Mol Biol 1998 0.89
23 A novel pyrrolidine analog of histamine as a potent, highly selective histamine H3 receptor agonist. J Med Chem 1995 0.88
24 Resistance of gluconeogenic and glycogenic pathways in obese-hyperglycemic mice. Am J Physiol 1975 0.86
25 Effect of the PAF antagonists, CV-3988 and L-652,731 on the pulmonary and hematological responses to guinea pig anaphylaxis. Pharmacol Res Commun 1988 0.86
26 Inhibition of sympathetic hypertensive responses in the guinea-pig by prejunctional histamine H3-receptors. Br J Pharmacol 1992 0.86
27 A novel class of platelet activating factor antagonists from Phoma sp. J Antibiot (Tokyo) 1993 0.86
28 Comparison of PDE 4 inhibitors, rolipram and SB 207499 (ariflo), in a rat model of pulmonary neutrophilia. Pulm Pharmacol Ther 2001 0.86
29 (R)-alpha-methylhistamine augments neural, cholinergic bronchospasm in guinea pigs by histamine H1 receptor activation. Eur J Pharmacol 1992 0.86
30 Mechanisms of allergic pulmonary eosinophilia in the mouse. J Allergy Clin Immunol 1994 0.86
31 Glucocorticosteroids inhibit leukotriene production. Ann Allergy Asthma Immunol 1997 0.86
32 5-HT3 receptors augment neuronal, cholinergic contractions in guinea pig trachea. Eur J Pharmacol 1993 0.85
33 Histamine H2-receptors in guinea pig peripheral airway smooth muscle. Life Sci 1979 0.84
34 In vitro glucocorticoid receptor binding and transcriptional activation by topically active glucocorticoids. Arzneimittelforschung 1998 0.84
35 NK(2)-receptor mediated contraction in monkey, guinea-pig and human airway smooth muscle. Neuropeptides 1999 0.83
36 Dual antagonists of platelet activating factor and histamine. Identification of structural requirements for dual activity of N-Acyl-4-(5,6-dihydro-11H-benzo [5,6]cyclohepta-[1,2-b]pyridin-11-ylidene)piperidines. J Med Chem 1991 0.83
37 Combined histamine H1 and H3 receptor blockade produces nasal decongestion in an experimental model of nasal congestion. Am J Rhinol 1999 0.83
38 Inhibition of experimental acute pulmonary inflammation by pirfenidone. Pulm Pharmacol Ther 2003 0.83
39 Further evidence for prejunctional GABA-B inhibition of cholinergic and peptidergic bronchoconstriction in guinea pigs: studies with new agonists and antagonists. Pharmacology 1993 0.82
40 Respiratory effects of baclofen and 3-aminopropylphosphinic acid in guinea-pigs. Br J Pharmacol 1995 0.81
41 Antihistamine activity, central nervous system and cardiovascular profiles of histamine H1 antagonists: comparative studies with loratadine, terfenadine and sedating antihistamines in guinea-pigs. Clin Exp Allergy 1995 0.81
42 Loratadine produces antihistamine activity without adverse CNS, ECG or cardiovascular effects in guinea pigs. Comparative studies with terfenadine and sedating antihistamines. Int Arch Allergy Immunol 1995 0.81
43 Sch 50971, an orally active histamine H3 receptor agonist, inhibits central neurogenic vascular inflammation and produces sedation in the guinea pig. J Pharmacol Exp Ther 1998 0.80
44 The role of neutrophils in LPS-induced changes in pulmonary function in conscious rats. Pulm Pharmacol Ther 2004 0.79
45 Sulfur-dioxide exposure increases TRPV1-mediated responses in nodose ganglia cells and augments cough in guinea pigs. Pulm Pharmacol Ther 2006 0.78
46 Antiallergic activity of loratadine, a non-sedating antihistamine. Allergy 1987 0.78
47 The guinea pig model for assessing cardiotoxic proclivities of second generation antihistamines. Arzneimittelforschung 1996 0.78
48 Anti-inflammatory activity of inhaled mometasone furoate in allergic mice. Arzneimittelforschung 1998 0.77
49 Desloratadine prevents compound 48/80-induced mast cell degranulation: visualization using a vital fluorescent dye technique. Allergy 2005 0.77
50 Histamine H3 receptors inhibit sympathetic modulation of airway microvascular leakage in allergic guinea pigs. Eur J Pharmacol 1994 0.77
51 Selective inhibition of peripheral histamine responses by loratadine and terfenadine. Eur J Pharmacol 1990 0.77
52 Effect of inhibition of arachidonic acid metabolism on anaphylaxis of guinea pig lung strips. Agents Actions 1980 0.76
53 Terfenadine, astemizole, and ebastine produce QTc interval prolongation in an experimental model predictive of adverse clinical ECG effects. Ann Allergy Asthma Immunol 1996 0.75
54 Potentiation of the hypoglycemic effect of insulin by thiorphan, an enkephalinase inhibitor. Eur J Pharmacol 1984 0.75
55 Trans-4-methyl-3-imidazoyl pyrrolidine as a potent, highly selective histamine H3 receptor agonist in vivo. Bioorg Med Chem Lett 1998 0.75
56 Antibronchoconstrictor activity of the intracellular calcium antagonist HA 1004 in guinea pigs. Pharmacology 1988 0.75
57 Evaluation of the CNS properties of SCH 29851, a potential non-sedating antihistamine. 1984. Agents Actions 1994 0.75
58 Sch 37370: a potent, orally active, dual antagonist of platelet-activating factor and histamine. J Pharmacol Exp Ther 1990 0.75
59 Effect of SCH 15280, a new bronchodilator, on cyclic 3',5'-nucleotide phosphodiesterase activity and cyclic 3',5'-adenosine monophosphate levels in guinea pig lung. Biochem Pharmacol 1977 0.75
60 Combined NK(1)and NK(2)receptor antagonists on the bronchoconstrictor response to NKA in dogs. Pulm Pharmacol Ther 1999 0.75
61 Effect of epinephrine on hepatic glycogen phosphorylase and synthetase activities in normal and pertussis-sensitized rats. Biochem Pharmacol 1970 0.75
62 Labetalol protects against the potentiation by propranolol of the bronchospasm to norepinephrine in guinea-pigs. Arch Int Pharmacodyn Ther 1987 0.75
63 Discovery and preliminary pharmacology of Sch 37370, a dual antagonist of PAF and histamine. Lipids 1991 0.75
64 Comparison of the protective effect of orciprenaline with an orciprenaline-oxymetazoline combination on experimental bronchospasm in guinea pigs. Arzneimittelforschung 1985 0.75
65 Bronchodilator and antiallergy activity of forskolin. Eur J Pharmacol 1985 0.75
66 Sch 37370: a new drug combining antagonism of platelet-activating factor (PAF) with antagonism of histamine. Agents Actions Suppl 1991 0.75
67 Studies on the pharmacology of the novel histamine H3 receptor agonist Sch 50971. Arzneimittelforschung 1998 0.75
68 Sch 37224, an experimental antiallergy compound, inhibits the neuropeptide component of hyperventilation- and nicotine-induced bronchoconstriction in guinea pigs. Pharmacology 1997 0.75
69 Cardiovascular profile of loratadine. Clin Exp Allergy 1999 0.75
70 Alteration in second phase platelet aggregation associated with an emotionally stressful activity. Thromb Haemost 1977 0.75
71 Bronchoconstrictor reactivity to NKA in allergic dogs: a comparison to histamine and methacholine. Pulm Pharmacol Ther 2001 0.75
72 Pharmacology of non-sedating H1 antihistamines. Agents Actions Suppl 1991 0.75
73 A method to measure dual NK1/NK2-antagonist activity in dogs. J Pharmacol Toxicol Methods 1998 0.75
74 Interferon-gamma and antibodies to interleukin-5 and interleukin-4 inhibit the pulmonary eosinophilia in allergic mice. Inflamm Res 1995 0.75
75 A magnetic resonance imaging evaluation of histamine-mediated allergic response in the guinea pig nasopharynx. J Allergy Clin Immunol 1993 0.75
76 Antiallergy agents. 1. Substituted 1,8-naphthyridin-2(1H)-ones as inhibitors of SRS-A release. J Med Chem 1988 0.75