Published in Mol Cells on April 30, 2006
The c-jun kinase/stress-activated pathway: regulation, function and role in human disease. Biochim Biophys Acta (2007) 2.83
Non-classical p38 map kinase functions: cell cycle checkpoints and survival. Int J Biol Sci (2008) 2.18
Atonal homolog 1 is a tumor suppressor gene. PLoS Biol (2009) 1.76
Regulation of innate immune response by MAP kinase phosphatase-1. Cell Signal (2007) 1.65
MAP kinase genes and colon and rectal cancer. Carcinogenesis (2012) 1.08
MAP Kinases and Prostate Cancer. J Signal Transduct (2011) 1.06
Differential cytokine regulation by NF-kappaB and AP-1 in Jurkat T-cells. BMC Immunol (2010) 1.04
CXCL13 mediates prostate cancer cell proliferation through JNK signalling and invasion through ERK activation. Cell Prolif (2011) 1.03
Oncogenic mutations regulate tumor microenvironment through induction of growth factors and angiogenic mediators. Oncogene (2010) 0.95
Oral administration of blueberry inhibits angiogenic tumor growth and enhances survival of mice with endothelial cell neoplasm. Antioxid Redox Signal (2009) 0.90
Increased JNK1 signaling pathway is responsible for ABCG2-mediated multidrug resistance in human colon cancer. PLoS One (2012) 0.87
Cucurbitacin-I (JSI-124) activates the JNK/c-Jun signaling pathway independent of apoptosis and cell cycle arrest in B leukemic cells. BMC Cancer (2011) 0.87
Transgenic expression of the Helicobacter pylori virulence factor CagA promotes apoptosis or tumorigenesis through JNK activation in Drosophila. PLoS Pathog (2012) 0.86
Identification of a potent herbal molecule for the treatment of breast cancer. BMC Cancer (2009) 0.84
Developmental regulation of TAC1 in peptidergic-induced human mesenchymal stem cells: implication for spinal cord injury in zebrafish. Stem Cells Dev (2011) 0.84
A soluble factor from Trypanosoma cruzi inhibits transforming growth factor-ß-induced MAP kinase activation and gene expression in dermal fibroblasts. PLoS One (2011) 0.82
Multiple endocrine neoplasia type 1 (MEN1) as a cancer predisposition syndrome: clues into the mechanisms of MEN1-related carcinogenesis. Yale J Biol Med (2006) 0.79
c-Jun N-terminal kinase is involved in the regulation of proliferation and apoptosis by integrin-linked kinase in human retinoblastoma cells. Graefes Arch Clin Exp Ophthalmol (2011) 0.79
Posttranslational modification of vesicular stomatitis virus glycoprotein, but not JNK inhibition, is the antiviral mechanism of SP600125. J Virol (2012) 0.77
Novel mechanism of JNK pathway activation by adenoviral E1A. Oncotarget (2014) 0.77
dMyc is required in retinal progenitors to prevent JNK-mediated retinal glial activation. PLoS Genet (2017) 0.75
MAGEA1 interacts with FBXW7 and regulates ubiquitin ligase-mediated turnover of NICD1 in breast and ovarian cancer cells. Oncogene (2017) 0.75
Interleukin-32: a cytokine and inducer of TNFalpha. Immunity (2005) 3.39
Restoration of Wnt-7a expression reverses non-small cell lung cancer cellular transformation through frizzled-9-mediated growth inhibition and promotion of cell differentiation. J Biol Chem (2005) 1.53
A specific and potent inhibitor of brassinosteroid biosynthesis possessing a dioxolane ring. J Agric Food Chem (2002) 1.06
Control of nodule number by the phytohormone abscisic Acid in the roots of two leguminous species. Plant Cell Physiol (2004) 1.01
Collaboration of JNKs and ERKs in nerve growth factor regulation of the neurofilament light chain promoter in PC12 cells. J Biol Chem (2001) 0.91
Brz220 interacts with DWF4, a cytochrome P450 monooxygenase in brassinosteroid biosynthesis, and exerts biological activity. Biosci Biotechnol Biochem (2008) 0.90
A 9-cis-epoxycarotenoid dioxygenase inhibitor for use in the elucidation of abscisic acid action mechanisms. Bioorg Med Chem (2006) 0.90
Neuroprotective effects of valproic acid against hemin toxicity: possible involvement of the down-regulation of heme oxygenase-1 by regulating ubiquitin-proteasomal pathway. Neurochem Int (2013) 0.86
Discovery of a potent small molecule SIRT1/2 inhibitor with anticancer effects. Int J Oncol (2013) 0.84
Synthesis of novel chemical probes for the study of tanshinone binding proteins. Bioorg Med Chem Lett (2006) 0.84
5,5'-substituted indirubin-3'-oxime derivatives as potent cyclin-dependent kinase inhibitors with anticancer activity. J Med Chem (2010) 0.82
Indirubin derivatives as potent FLT3 inhibitors with anti-proliferative activity of acute myeloid leukemic cells. Bioorg Med Chem Lett (2010) 0.80
Synthesis and structure-activity relationship of aminopyridines with substituted benzoxazoles as c-Met kinase inhibitors. Bioorg Med Chem Lett (2012) 0.79
Triadimefon, a fungicidal triazole-type P450 inhibitor, induces brassinosteroid deficiency-like phenotypes in plants and binds to DWF4 protein in the brassinosteroid biosynthesis pathway. Biochem J (2003) 0.79
Discovery of aminopyridines substituted with benzoxazole as orally active c-Met kinase inhibitors. Bioorg Med Chem Lett (2010) 0.78
Flavonoids as receptor tyrosine kinase FLT3 inhibitors. Bioorg Med Chem Lett (2013) 0.77
Design and synthesis of triazolopyridazines substituted with methylisoquinolinone as selective c-Met kinase inhibitors. Bioorg Med Chem Lett (2011) 0.77
KDM4 histone demethylase inhibitors for anti-cancer agents: a patent review. Expert Opin Ther Pat (2014) 0.77
Rational design of peptidomimetics for class B GPCRs: potent non-peptide GLP-1 receptor agonists. Adv Exp Med Biol (2009) 0.75
FMS-like tyrosine kinase 3 inhibitors: a patent review. Expert Opin Ther Pat (2011) 0.75