| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Cardiac mitochondria in heart failure: decrease in respirasomes and oxidative phosphorylation.
|
Cardiovasc Res
|
2008
|
2.66
|
|
2
|
Mitral valve surgery in heart failure: insights from the Acorn Clinical Trial.
|
J Thorac Cardiovasc Surg
|
2006
|
2.62
|
|
3
|
Ranolazine improves abnormal repolarization and contraction in left ventricular myocytes of dogs with heart failure by inhibiting late sodium current.
|
J Cardiovasc Electrophysiol
|
2006
|
2.56
|
|
4
|
Gating of the late Na+ channel in normal and failing human myocardium.
|
J Mol Cell Cardiol
|
2002
|
1.88
|
|
5
|
Parasympathetic nervous system and heart failure: pathophysiology and potential implications for therapy.
|
Circulation
|
2008
|
1.83
|
|
6
|
Effect of adjustable passive constraint on the failing left ventricle: a finite-element model study.
|
Ann Thorac Surg
|
2010
|
1.76
|
|
7
|
Effects of long-term monotherapy with eplerenone, a novel aldosterone blocker, on progression of left ventricular dysfunction and remodeling in dogs with heart failure.
|
Circulation
|
2002
|
1.63
|
|
8
|
Fish oil, but not flaxseed oil, decreases inflammation and prevents pressure overload-induced cardiac dysfunction.
|
Cardiovasc Res
|
2008
|
1.62
|
|
9
|
Hemodynamic, echocardiographic, and neurohormonal effects of istaroxime, a novel intravenous inotropic and lusitropic agent: a randomized controlled trial in patients hospitalized with heart failure.
|
J Am Coll Cardiol
|
2008
|
1.60
|
|
10
|
Peripheral venous congestion causes inflammation, neurohormonal, and endothelial cell activation.
|
Eur Heart J
|
2013
|
1.60
|
|
11
|
Low carbohydrate/high-fat diet attenuates cardiac hypertrophy, remodeling, and altered gene expression in hypertension.
|
Hypertension
|
2006
|
1.56
|
|
12
|
Mechanisms of heart failure with well preserved ejection fraction in dogs following limited coronary microembolization.
|
Cardiovasc Res
|
2004
|
1.53
|
|
13
|
Differential effects of saturated and unsaturated fatty acid diets on cardiomyocyte apoptosis, adipose distribution, and serum leptin.
|
Am J Physiol Heart Circ Physiol
|
2006
|
1.52
|
|
14
|
CVT-4325 inhibits myocardial fatty acid uptake and improves left ventricular systolic function without increasing myocardial oxygen consumption in dogs with chronic heart failure.
|
Cardiovasc Drugs Ther
|
2007
|
1.52
|
|
15
|
Chronic heart failure slows late sodium current in human and canine ventricular myocytes: implications for repolarization variability.
|
Eur J Heart Fail
|
2006
|
1.47
|
|
16
|
Clinical evaluation of the CorCap Cardiac Support Device in patients with dilated cardiomyopathy.
|
Ann Thorac Surg
|
2007
|
1.37
|
|
17
|
Modulation of late sodium current by Ca2+, calmodulin, and CaMKII in normal and failing dog cardiomyocytes: similarities and differences.
|
Am J Physiol Heart Circ Physiol
|
2008
|
1.36
|
|
18
|
Targeting myocardial substrate metabolism in heart failure: potential for new therapies.
|
Eur J Heart Fail
|
2012
|
1.36
|
|
19
|
Cardiac SR-coupled PP1 activity and expression are increased and inhibitor 1 protein expression is decreased in failing hearts.
|
Am J Physiol Heart Circ Physiol
|
2003
|
1.32
|
|
20
|
Clinical trials of pharmacological therapies in acute heart failure syndromes: lessons learned and directions forward.
|
Circ Heart Fail
|
2010
|
1.27
|
|
21
|
A method for automatically optimizing medical devices for treating heart failure: designing polymeric injection patterns.
|
J Biomech Eng
|
2009
|
1.25
|
|
22
|
Cyclosporine A attenuates mitochondrial permeability transition and improves mitochondrial respiratory function in cardiomyocytes isolated from dogs with heart failure.
|
J Mol Cell Cardiol
|
2006
|
1.21
|
|
23
|
Late sodium current contributes to diastolic cell Ca2+ accumulation in chronic heart failure.
|
J Physiol Sci
|
2010
|
1.18
|
|
24
|
Abnormal mitochondrial respiration in skeletal muscle in patients with peripheral arterial disease.
|
J Vasc Surg
|
2003
|
1.16
|
|
25
|
Short-term treatment with ranolazine improves mechanical efficiency in dogs with chronic heart failure.
|
Circ Res
|
2002
|
1.12
|
|
26
|
Upregulation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase activity increases oxidative stress in failing human heart.
|
J Card Fail
|
2007
|
1.11
|
|
27
|
Post-transcriptional alterations in the expression of cardiac Na+ channel subunits in chronic heart failure.
|
J Mol Cell Cardiol
|
2004
|
1.11
|
|
28
|
Mitral valve repair in heart failure: five-year follow-up from the mitral valve replacement stratum of the Acorn randomized trial.
|
J Thorac Cardiovasc Surg
|
2011
|
1.11
|
|
29
|
Moderate severity heart failure does not involve a downregulation of myocardial fatty acid oxidation.
|
Am J Physiol Heart Circ Physiol
|
2004
|
1.09
|
|
30
|
Therapy with cardiac contractility modulation electrical signals improves left ventricular function and remodeling in dogs with chronic heart failure.
|
J Am Coll Cardiol
|
2007
|
1.05
|
|
31
|
High intake of saturated fat, but not polyunsaturated fat, improves survival in heart failure despite persistent mitochondrial defects.
|
Cardiovasc Res
|
2011
|
1.05
|
|
32
|
Effects of istaroxime on diastolic stiffness in acute heart failure syndromes: results from the Hemodynamic, Echocardiographic, and Neurohormonal Effects of Istaroxime, a Novel Intravenous Inotropic and Lusitropic Agent: a Randomized Controlled Trial in Patients Hospitalized with Heart Failure (HORIZON-HF) trial.
|
Am Heart J
|
2009
|
1.04
|
|
33
|
Sustained benefits of the CorCap Cardiac Support Device on left ventricular remodeling: three year follow-up results from the Acorn clinical trial.
|
Ann Thorac Surg
|
2007
|
1.04
|
|
34
|
Polymer-based restoration of left ventricular mechanics.
|
Cell Transplant
|
2012
|
1.04
|
|
35
|
Cardiac contractility modulation electrical signals improve myocardial gene expression in patients with heart failure.
|
J Am Coll Cardiol
|
2008
|
1.03
|
|
36
|
Ranolazine combined with enalapril or metoprolol prevents progressive LV dysfunction and remodeling in dogs with moderate heart failure.
|
Am J Physiol Heart Circ Physiol
|
2008
|
1.03
|
|
37
|
Site selection in global clinical trials in patients hospitalized for heart failure: perceived problems and potential solutions.
|
Heart Fail Rev
|
2014
|
1.03
|
|
38
|
Beneficial effects of the CorCap cardiac support device: five-year results from the Acorn Trial.
|
J Thorac Cardiovasc Surg
|
2011
|
1.02
|
|
39
|
Agents with inotropic properties for the management of acute heart failure syndromes. Traditional agents and beyond.
|
Heart Fail Rev
|
2009
|
1.02
|
|
40
|
Mineralocorticoid receptor antagonists for heart failure with reduced ejection fraction: integrating evidence into clinical practice.
|
Eur Heart J
|
2012
|
1.02
|
|
41
|
Reverse changes in cardiac substrate oxidation in dogs recovering from heart failure.
|
Am J Physiol Heart Circ Physiol
|
2008
|
1.01
|
|
42
|
Vagus nerve stimulation improves left ventricular function in a canine model of chronic heart failure.
|
Eur J Heart Fail
|
2013
|
0.99
|
|
43
|
β-adrenergic receptor blockade reduces endoplasmic reticulum stress and normalizes calcium handling in a coronary embolization model of heart failure in canines.
|
Cardiovasc Res
|
2011
|
0.98
|
|
44
|
Phase III clinical trial end points in acute heart failure syndromes: a virtual roundtable with the Acute Heart Failure Syndromes International Working Group.
|
Am Heart J
|
2009
|
0.98
|
|
45
|
Association of arginine vasopressin levels with outcomes and the effect of V2 blockade in patients hospitalized for heart failure with reduced ejection fraction: insights from the EVEREST trial.
|
Circ Heart Fail
|
2012
|
0.97
|
|
46
|
Chronic monotherapy with rosuvastatin prevents progressive left ventricular dysfunction and remodeling in dogs with heart failure.
|
J Am Coll Cardiol
|
2007
|
0.96
|
|
47
|
Reduced Ca2+-calmodulin-dependent protein kinase activity and expression in LV myocardium of dogs with heart failure.
|
Am J Physiol Heart Circ Physiol
|
2002
|
0.96
|
|
48
|
Effects of adiponectin deficiency on structural and metabolic remodeling in mice subjected to pressure overload.
|
Am J Physiol Heart Circ Physiol
|
2010
|
0.94
|
|
49
|
Molecular mechanisms of reduced sarcoplasmic reticulum Ca(2+) uptake in human failing left ventricular myocardium.
|
J Heart Lung Transplant
|
2002
|
0.93
|
|
50
|
Augmentation of left ventricular wall thickness with alginate hydrogel implants improves left ventricular function and prevents progressive remodeling in dogs with chronic heart failure.
|
JACC Heart Fail
|
2013
|
0.92
|
|
51
|
Enhanced resistance to permeability transition in interfibrillar cardiac mitochondria in dogs: effects of aging and long-term aldosterone infusion.
|
Am J Physiol Heart Circ Physiol
|
2012
|
0.92
|
|
52
|
Post-transcriptional silencing of SCN1B and SCN2B genes modulates late sodium current in cardiac myocytes from normal dogs and dogs with chronic heart failure.
|
Am J Physiol Heart Circ Physiol
|
2011
|
0.91
|
|
53
|
Inhibition of mitochondrial permeability transition pores by cyclosporine A improves cytochrome C oxidase function and increases rate of ATP synthesis in failing cardiomyocytes.
|
Heart Fail Rev
|
2005
|
0.91
|
|
54
|
Selective matrix metalloproteinase inhibition attenuates progression of left ventricular dysfunction and remodeling in dogs with chronic heart failure.
|
Am J Physiol Heart Circ Physiol
|
2006
|
0.91
|
|
55
|
Enhanced inotropic state of the failing left ventricle by cardiac contractility modulation electrical signals is not associated with increased myocardial oxygen consumption.
|
J Card Fail
|
2007
|
0.90
|
|
56
|
Venous congestion and endothelial cell activation in acute decompensated heart failure.
|
Curr Heart Fail Rep
|
2010
|
0.90
|
|
57
|
Hemodynamic unloading of the failing left ventricle using an arterial-to-arterial extracorporeal flow circuit.
|
Ann Thorac Surg
|
2004
|
0.90
|
|
58
|
Current management and future directions for the treatment of patients hospitalized for heart failure with low blood pressure.
|
Heart Fail Rev
|
2013
|
0.90
|
|
59
|
Cardiac contractility modulation electrical signals normalize activity, expression, and phosphorylation of the Na+-Ca2+ exchanger in heart failure.
|
J Card Fail
|
2008
|
0.90
|
|
60
|
Effects of long-term monotherapy with metoprolol CR/XL on the progression of left ventricular dysfunction and remodeling in dogs with chronic heart failure.
|
Cardiovasc Drugs Ther
|
2002
|
0.89
|
|
61
|
Reduced inhibitor 1 and 2 activity is associated with increased protein phosphatase type 1 activity in left ventricular myocardium of one-kidney, one-clip hypertensive rats.
|
Mol Cell Biochem
|
2005
|
0.89
|
|
62
|
Hypoxia-induced cleavage of caspase-3 and DFF45/ICAD in human failed cardiomyocytes.
|
Am J Physiol Heart Circ Physiol
|
2002
|
0.89
|
|
63
|
Electrical signals applied during the absolute refractory period: an investigational treatment for advanced heart failure in patients with normal QRS duration.
|
J Am Coll Cardiol
|
2005
|
0.88
|
|
64
|
Acute heart failure as "acute endothelitis"--Interaction of fluid overload and endothelial dysfunction.
|
Eur J Heart Fail
|
2008
|
0.88
|
|
65
|
Istaroxime, a first in class new chemical entity exhibiting SERCA-2 activation and Na-K-ATPase inhibition: a new promising treatment for acute heart failure syndromes?
|
Heart Fail Rev
|
2009
|
0.88
|
|
66
|
Glucose 6-phosphate dehydrogenase deficiency increases redox stress and moderately accelerates the development of heart failure.
|
Circ Heart Fail
|
2012
|
0.88
|
|
67
|
Review of current and investigational pharmacologic agents for acute heart failure syndromes.
|
Am J Cardiol
|
2006
|
0.88
|
|
68
|
Marine n3 polyunsaturated fatty acids enhance resistance to mitochondrial permeability transition in heart failure but do not improve survival.
|
Am J Physiol Heart Circ Physiol
|
2012
|
0.86
|
|
69
|
Relationship between right cervical vagus nerve stimulation and atrial fibrillation inducibility: therapeutic intensities do not increase arrhythmogenesis.
|
Heart Rhythm
|
2008
|
0.85
|
|
70
|
Effects of chronic therapy with cardiac contractility modulation electrical signals on cytoskeletal proteins and matrix metalloproteinases in dogs with heart failure.
|
Cardiology
|
2007
|
0.85
|
|
71
|
Ca(2+)-binding proteins in dogs with heart failure: effects of cardiac contractility modulation electrical signals.
|
Clin Transl Sci
|
2009
|
0.85
|
|
72
|
Expression of cytoskeletal, linkage and extracellular proteins in failing dog myocardium.
|
Heart Fail Rev
|
2005
|
0.84
|
|
73
|
Hypoxia, angiotensin-II, and norepinephrine mediated apoptosis is stimulus specific in canine failed cardiomyocytes: a role for p38 MAPK, Fas-L and cyclin D1.
|
Eur J Heart Fail
|
2003
|
0.84
|
|
74
|
Contribution of sodium channel neuronal isoform Nav1.1 to late sodium current in ventricular myocytes from failing hearts.
|
J Physiol
|
2014
|
0.84
|
|
75
|
Rationale, design, and methods for a pivotal randomized clinical trial for the assessment of a cardiac support device in patients with New York health association class III-IV heart failure.
|
J Card Fail
|
2004
|
0.84
|
|
76
|
Bendavia, a mitochondria-targeting peptide, improves postinfarction cardiac function, prevents adverse left ventricular remodeling, and restores mitochondria-related gene expression in rats.
|
J Cardiovasc Pharmacol
|
2014
|
0.84
|
|
77
|
The immunological axis in heart failure: importance of the leukocyte differential.
|
Heart Fail Rev
|
2013
|
0.84
|
|
78
|
Mitochondrial inner membrane lipids and proteins as targets for decreasing cardiac ischemia/reperfusion injury.
|
Pharmacol Ther
|
2013
|
0.84
|
|
79
|
Activation of endothelial cells in conduit veins of dogs with heart failure and veins of normal dogs after vascular stretch by acute volume loading.
|
J Card Fail
|
2009
|
0.83
|
|
80
|
Soluble guanylate cyclase: a potential therapeutic target for heart failure.
|
Heart Fail Rev
|
2013
|
0.83
|
|
81
|
Long-term therapy with the acorn cardiac support device normalizes gene expression of growth factors and gelatinases in dogs with heart failure.
|
J Heart Lung Transplant
|
2005
|
0.83
|
|
82
|
Myocardial transfection with naked DNA plasmid encoding hepatocyte growth factor prevents the progression of heart failure in dogs.
|
Am J Physiol Heart Circ Physiol
|
2011
|
0.83
|
|
83
|
Heart rate: a prognostic factor and therapeutic target in chronic heart failure. The distinct roles of drugs with heart rate-lowering properties.
|
Eur J Heart Fail
|
2013
|
0.82
|
|
84
|
Reverse remodeling and enhanced adrenergic reserve from passive external support in experimental dilated heart failure.
|
J Am Coll Cardiol
|
2002
|
0.82
|
|
85
|
Acute vagal stimulation attenuates cardiac metabolic response to β-adrenergic stress.
|
J Physiol
|
2012
|
0.82
|
|
86
|
Inhibition of type 1 protein phosphatase activity by activation of beta-adrenoceptors in ventricular myocardium.
|
Biochem Pharmacol
|
2002
|
0.82
|
|
87
|
Metabolic therapy for ischemic heart disease: the rationale for inhibition of fatty acid oxidation.
|
Heart Fail Rev
|
2005
|
0.82
|
|
88
|
Long-term effects of non-excitatory cardiac contractility modulation electric signals on the progression of heart failure in dogs.
|
Eur J Heart Fail
|
2004
|
0.81
|
|
89
|
Darbepoetin-alpha prevents progressive left ventricular dysfunction and remodeling in nonanemic dogs with heart failure.
|
Am J Physiol Heart Circ Physiol
|
2008
|
0.81
|
|
90
|
Short term effects of milrinone on biomarkers of necrosis, apoptosis, and inflammation in patients with severe heart failure.
|
J Transl Med
|
2009
|
0.81
|
|
91
|
Prognostic implications of renal dysfunction in patients hospitalized with heart failure: data from the last decade of clinical investigations.
|
Heart Fail Rev
|
2013
|
0.81
|
|
92
|
Effect of long-term monotherapy with the aldosterone receptor blocker eplerenone on cytoskeletal proteins and matrix metalloproteinases in dogs with heart failure.
|
Cardiovasc Drugs Ther
|
2007
|
0.81
|
|
93
|
Takotsubo cardiomyopathy.
|
Heart Fail Rev
|
2014
|
0.80
|
|
94
|
Hemodynamic and neurohormonal predictors and consequences of the development of atrial fibrillation in dogs with chronic heart failure.
|
J Card Fail
|
2006
|
0.80
|
|
95
|
Evidence of viral infection in the myocardium of American and Japanese patients with idiopathic dilated cardiomyopathy.
|
Am J Cardiol
|
2004
|
0.80
|
|
96
|
Cardiac contractility modulation with nonexcitatory electric signals improves left ventricular function in dogs with chronic heart failure.
|
J Card Fail
|
2003
|
0.80
|
|
97
|
Effects of acute intravenous infusion of apelin on left ventricular function in dogs with advanced heart failure.
|
J Card Fail
|
2013
|
0.79
|
|
98
|
Association of genetic variation with gene expression and protein abundance within the natriuretic peptide pathway.
|
J Cardiovasc Transl Res
|
2013
|
0.79
|
|
99
|
Reduced sarcoplasmic reticulum Ca2+ uptake and increased Na+-Ca2+ exchanger expression in left ventricle myocardium of dogs with progression of heart failure.
|
Heart Vessels
|
2005
|
0.79
|
|
100
|
Effects of chronic neutral endopeptidase inhibition on the progression of left ventricular dysfunction and remodeling in dogs with moderate heart failure.
|
Cardiovasc Drugs Ther
|
2002
|
0.78
|
|
101
|
Animal models of insulin resistance and heart failure.
|
Heart Fail Rev
|
2014
|
0.78
|
|
102
|
Venous congestion, endothelial and neurohormonal activation in acute decompensated heart failure: cause or effect?
|
Curr Heart Fail Rep
|
2015
|
0.78
|
|
103
|
Acute heart failure syndromes and coronary perfusion.
|
J Am Coll Cardiol
|
2008
|
0.78
|
|
104
|
Atenolol is inferior to metoprolol in improving left ventricular function and preventing ventricular remodeling in dogs with heart failure.
|
Cardiology
|
2008
|
0.78
|
|
105
|
Influence of i.v. haloperidol on ventricular repolarization and monophasic action potential duration in anesthetized dogs.
|
Chest
|
2004
|
0.77
|
|
106
|
Comparison of β-blocker effectiveness in heart failure patients with preserved ejection fraction versus those with reduced ejection fraction.
|
J Card Fail
|
2013
|
0.77
|
|
107
|
Effects of the AT1-receptor antagonist eprosartan on the progression of left ventricular dysfunction in dogs with heart failure.
|
Br J Pharmacol
|
2003
|
0.77
|
|
108
|
Long-term pharmacological activation of PPARgamma does not prevent left ventricular remodeling in dogs with advanced heart failure.
|
Cardiovasc Drugs Ther
|
2007
|
0.77
|
|
109
|
Rationale and design of the hemodynamic, echocardiographic and neurohormonal effects of istaroxime, a novel intravenous inotropic and lusitropic agent: a randomized controlled trial in patients hospitalized with heart failure (HORIZON-HF) trial.
|
Am J Ther
|
2008
|
0.77
|
|
110
|
Reversal of maladaptive gene program in left ventricular myocardium of dogs with heart failure following long-term therapy with the Acorn Cardiac Support Device.
|
Heart Fail Rev
|
2005
|
0.77
|
|
111
|
Genome-wide approach to identify novel candidate genes for beta blocker response in heart failure using an experimental model.
|
Discov Med
|
2011
|
0.77
|
|
112
|
Calpain inhibition reduces amplitude and accelerates decay of the late sodium current in ventricular myocytes from dogs with chronic heart failure.
|
PLoS One
|
2013
|
0.77
|
|
113
|
Left atrial reverse remodeling in dogs with moderate and advanced heart failure treated with a passive mechanical containment device: an echocardiographic study.
|
J Card Fail
|
2007
|
0.77
|
|
114
|
Evaluation of docosahexaenoic acid in a dog model of hypertension induced left ventricular hypertrophy.
|
J Cardiovasc Transl Res
|
2013
|
0.76
|
|
115
|
Reverse remodeling and enhanced inotropic reserve from the cardiac support device in experimental cardiac failure.
|
J Card Fail
|
2004
|
0.76
|
|
116
|
Pleiotropic effects of long-term monotherapy with rosuvastatin in dogs with moderate heart failure.
|
Cardiology
|
2012
|
0.75
|
|
117
|
Acute intravenous infusion of an adenosine regulating agent improves left ventricular function in dogs with advanced heart failure.
|
Cardiovasc Drugs Ther
|
2013
|
0.75
|
|
118
|
Differentiation of arginine vasopressin antagonistic effects by selective V2 versus dual V2/V1a receptor blockade in a preclinical heart failure model.
|
Am J Ther
|
2011
|
0.75
|
|
119
|
Improvement of cardiac sarcoplasmic reticulum calcium cycling in dogs with heart failure following long-term therapy with the Acorn Cardiac Support Device.
|
Heart Fail Rev
|
2005
|
0.75
|
|
120
|
Assessment of sarcoplasmic reticulum Ca2+-uptake during the development of left ventricular hypertrophy.
|
Biochem Pharmacol
|
2003
|
0.75
|
|
121
|
Left ventricular histomorphometric findings in dogs with heart failure treated with the Acorn Cardiac Support Device.
|
Heart Fail Rev
|
2005
|
0.75
|
|
122
|
Effects of pre-existing left ventricular hypertrophy on ventricular dysfunction and remodeling following myocardial infarction in rats.
|
J Heart Lung Transplant
|
2002
|
0.75
|
|
123
|
The Heart Failure Society of America in 2020: a vision for the future.
|
J Card Fail
|
2012
|
0.75
|
|
124
|
Istaroxime: an investigational luso-inotropic agent for acute heart failure syndromes.
|
Am J Cardiol
|
2006
|
0.75
|
|
125
|
Reversal of ventricular remodeling: important to establish and difficult to define.
|
Eur J Heart Fail
|
2006
|
0.75
|