Published in Am J Physiol Gastrointest Liver Physiol on June 01, 2006
Mechanisms of hepatic fibrogenesis. Gastroenterology (2008) 11.98
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. Arch Toxicol (2013) 3.00
Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity. Drug Metab Rev (2012) 2.76
Hydrogen sulfide attenuates hepatic ischemia-reperfusion injury: role of antioxidant and antiapoptotic signaling. Am J Physiol Heart Circ Physiol (2008) 2.19
Uric acid promotes an acute inflammatory response to sterile cell death in mice. J Clin Invest (2010) 1.97
Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury. FASEB J (2007) 1.94
Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity. Liver Int (2011) 1.92
Endocannabinoids and cannabinoid receptors in ischaemia-reperfusion injury and preconditioning. Br J Pharmacol (2007) 1.65
Toll-like receptor 9 inhibition confers protection from liver ischemia-reperfusion injury. Hepatology (2010) 1.60
Cell-cycle arrest and acute kidney injury: the light and the dark sides. Nephrol Dial Transplant (2015) 1.59
Chronic plus binge ethanol feeding synergistically induces neutrophil infiltration and liver injury in mice: a critical role for E-selectin. Hepatology (2013) 1.58
Interleukin-8 is activated in patients with chronic liver diseases and associated with hepatic macrophage accumulation in human liver fibrosis. PLoS One (2011) 1.57
Results of the TOP Study: Prospectively Randomized Multicenter Trial of an Ex Vivo Tacrolimus Rinse Before Transplantation in EDC Livers. Transplant Direct (2016) 1.51
Mechanisms of immune-mediated liver injury. Toxicol Sci (2010) 1.48
Neutrophil activation during acetaminophen hepatotoxicity and repair in mice and humans. Toxicol Appl Pharmacol (2014) 1.46
Current issues with acetaminophen hepatotoxicity--a clinically relevant model to test the efficacy of natural products. Life Sci (2011) 1.46
Oxidative inactivation of key mitochondrial proteins leads to dysfunction and injury in hepatic ischemia reperfusion. Gastroenterology (2008) 1.42
Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and apoptosis. J Leukoc Biol (2007) 1.39
Peroxiredoxin-6 protects against mitochondrial dysfunction and liver injury during ischemia-reperfusion in mice. Am J Physiol Gastrointest Liver Physiol (2008) 1.38
Current strategies to minimize hepatic ischemia-reperfusion injury by targeting reactive oxygen species. Transplant Rev (Orlando) (2012) 1.38
Role of caspase-1 and interleukin-1beta in acetaminophen-induced hepatic inflammation and liver injury. Toxicol Appl Pharmacol (2010) 1.38
Interleukin-37 reduces liver inflammatory injury via effects on hepatocytes and non-parenchymal cells. J Gastroenterol Hepatol (2012) 1.33
Novel insight into mechanisms of cholestatic liver injury. World J Gastroenterol (2012) 1.31
Acetaminophen-induced hepatic neutrophil accumulation and inflammatory liver injury in CD18-deficient mice. Liver Int (2010) 1.29
Tissue-resident macrophages protect the liver from ischemia reperfusion injury via a heme oxygenase-1-dependent mechanism. Mol Ther (2008) 1.28
Invariant natural killer T cells suppress the neutrophil inflammatory response in a mouse model of cholestatic liver damage. Gastroenterology (2008) 1.25
Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death. Free Radic Biol Med (2011) 1.24
Interleukin-33 is hepatoprotective during liver ischemia/reperfusion in mice. Hepatology (2012) 1.21
Role of the Nalp3 inflammasome in acetaminophen-induced sterile inflammation and liver injury. Toxicol Appl Pharmacol (2011) 1.21
CXC chemokines play a critical role in liver injury, recovery, and regeneration. Am J Surg (2009) 1.16
Mouse model of liver ischemia and reperfusion injury: method for studying reactive oxygen and nitrogen metabolites in vivo. Free Radic Biol Med (2008) 1.13
Role of interleukin-17A in cell-mediated protection against Staphylococcus aureus infection in mice immunized with the fibrinogen-binding domain of clumping factor A. Infect Immun (2010) 1.13
Sulfatide-mediated activation of type II natural killer T cells prevents hepatic ischemic reperfusion injury in mice. Gastroenterology (2010) 1.13
Ischemia/Reperfusion injury in liver surgery and transplantation: pathophysiology. HPB Surg (2012) 1.12
Inhibition of TNF-α protects against hepatic ischemia-reperfusion injury in rats via NF-κB dependent pathway. Naunyn Schmiedebergs Arch Pharmacol (2012) 1.09
Plasma biomarkers of liver injury and inflammation demonstrate a lack of apoptosis during obstructive cholestasis in mice. Toxicol Appl Pharmacol (2013) 1.08
Subnormothermic machine perfusion at both 20°C and 30°C recovers ischemic rat livers for successful transplantation. J Surg Res (2011) 1.06
Endocannabinoids and liver disease. III. Endocannabinoid effects on immune cells: implications for inflammatory liver diseases. Am J Physiol Gastrointest Liver Physiol (2008) 1.05
A new cannabinoid CB2 receptor agonist HU-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury. Br J Pharmacol (2012) 1.04
Oxidant stress-induced liver injury in vivo: role of apoptosis, oncotic necrosis, and c-Jun NH2-terminal kinase activation. Am J Physiol Gastrointest Liver Physiol (2009) 1.02
Human heat shock protein 27 overexpressing mice are protected against hepatic ischemia and reperfusion injury. Transplantation (2009) 1.00
Preactivation of NKT cells with alpha-GalCer protects against hepatic ischemia-reperfusion injury in mouse by a mechanism involving IL-13 and adenosine A2A receptor. Am J Physiol Gastrointest Liver Physiol (2009) 0.99
Cellular and molecular mechanisms in the pathogenesis of liver fibrosis: An update. World J Gastroenterol (2014) 0.97
On, around, and through: neutrophil-endothelial interactions in innate immunity. Physiology (Bethesda) (2011) 0.95
Reduced inflammatory response and increased microcirculatory disturbances during hepatic ischemia-reperfusion injury in steatotic livers of ob/ob mice. Am J Physiol Gastrointest Liver Physiol (2007) 0.94
Impact of intravascular hemolysis in malaria on liver dysfunction: involvement of hepatic free heme overload, NF-κB activation, and neutrophil infiltration. J Biol Chem (2012) 0.94
The inhibition of neutrophil elastase ameliorates mouse liver damage due to ischemia and reperfusion. Liver Transpl (2009) 0.93
Hepatocellular protection by nitric oxide or nitrite in ischemia and reperfusion injury. Arch Biochem Biophys (2008) 0.92
Human heat shock protein 27-overexpressing mice are protected against acute kidney injury after hepatic ischemia and reperfusion. Am J Physiol Renal Physiol (2009) 0.91
Hydrogen peroxide mobilizes Ca2+ through two distinct mechanisms in rat hepatocytes. Acta Pharmacol Sin (2008) 0.89
Osteopontin is an initial mediator of inflammation and liver injury during obstructive cholestasis after bile duct ligation in mice. Toxicol Lett (2013) 0.89
Experimental models of hepatotoxicity related to acute liver failure. Toxicol Appl Pharmacol (2015) 0.88
Receptor activator of nuclear factor-κB ligand (RANKL) protects against hepatic ischemia/reperfusion injury in mice. Hepatology (2012) 0.88
Δ8-Tetrahydrocannabivarin prevents hepatic ischaemia/reperfusion injury by decreasing oxidative stress and inflammatory responses through cannabinoid CB2 receptors. Br J Pharmacol (2012) 0.88
Autophagy and liver ischemia-reperfusion injury. Biomed Res Int (2015) 0.88
Role of host genetics in fibrosis. Fibrogenesis Tissue Repair (2009) 0.86
NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma. Nat Commun (2015) 0.85
Enteric infection with Citrobacter rodentium induces coagulative liver necrosis and hepatic inflammation prior to peak infection and colonic disease. PLoS One (2012) 0.85
Protective effect of intermittent clamping of the portal triad in the rat liver on liver ischemia-reperfusion injury. Hepat Mon (2011) 0.84
Protective Effects of Geniposide and Genipin against Hepatic Ischemia/Reperfusion Injury in Mice. Biomol Ther (Seoul) (2013) 0.84
Tissue factor contributes to neutrophil CD11b expression in alpha-naphthylisothiocyanate-treated mice. Toxicol Appl Pharmacol (2010) 0.83
Cyclopamine attenuates acute warm ischemia reperfusion injury in cholestatic rat liver: hope for marginal livers. Mol Pharm (2011) 0.83
Transcriptome analysis of hepatocytes after partial hepatectomy in rats. Dev Genes Evol (2010) 0.83
Importance of TLR2 on hepatic immune and non-immune cells to attenuate the strong inflammatory liver response during Trypanosoma cruzi acute infection. PLoS Negl Trop Dis (2010) 0.83
Suppressor of cytokine signaling expression with increasing severity of murine hepatic ischemia-reperfusion injury. J Hepatol (2008) 0.82
Hemorrhage-induced hepatic injury and hypoperfusion can be prevented by direct peritoneal resuscitation. J Gastrointest Surg (2009) 0.82
Reactive oxygen species in the normal and acutely injured liver. J Hepatol (2011) 0.82
Liver apoptosis is age dependent and is reduced by activation of peroxisome proliferator-activated receptor-gamma in hemorrhagic shock. Am J Physiol Gastrointest Liver Physiol (2009) 0.82
Microbiota and nonalcoholic steatohepatitis. Semin Immunopathol (2013) 0.82
Nitrosative and oxidative stresses contribute to post-ischemic liver injury following severe hemorrhagic shock: the role of hypoxemic resuscitation. PLoS One (2012) 0.81
The mechanisms and physiological relevance of glycocalyx degradation in hepatic ischemia/reperfusion injury. Antioxid Redox Signal (2014) 0.81
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy. Int J Mol Sci (2015) 0.81
VEGFR1-positive macrophages facilitate liver repair and sinusoidal reconstruction after hepatic ischemia/reperfusion injury. PLoS One (2014) 0.81
Ron receptor-dependent gene regulation in a mouse model of endotoxin-induced acute liver failure. Hepatobiliary Pancreat Dis Int (2012) 0.80
Protective effect of the combinations of glycyrrhizic, ferulic and cinnamic acid pretreatment on myocardial ischemia-reperfusion injury in rats. Exp Ther Med (2014) 0.80
Roles of hepatocyte and myeloid CXC chemokine receptor-2 in liver recovery and regeneration after ischemia/reperfusion in mice. Hepatology (2013) 0.80
Divergent roles of superoxide and nitric oxide in liver ischemia and reperfusion injury. J Clin Biochem Nutr (2010) 0.79
Absence of a p53 allele delays nitrogen mustard-induced early apoptosis and inflammation of murine skin. Toxicology (2013) 0.79
The Reg3α (HIP/PAP) Lectin Suppresses Extracellular Oxidative Stress in a Murine Model of Acute Liver Failure. PLoS One (2015) 0.79
Aggravation of post-ischemic liver injury by overexpression of insulin-like growth factor binding protein 3. Sci Rep (2015) 0.79
Activation of NF-κB after chronic ethanol intake and haemorrhagic shock/resuscitation in mice. Br J Pharmacol (2013) 0.79
Atrial natriuretic peptide reduces hepatic ischemia-reperfusion injury in rabbits. J Anesth (2013) 0.79
Role of matrix metalloproteinases in cholestasis and hepatic ischemia/reperfusion injury: A review. World J Gastroenterol (2015) 0.78
Chemokines in chronic liver allograft dysfunction pathogenesis and potential therapeutic targets. Clin Dev Immunol (2013) 0.78
Suppressive effect of orthovanadate on hepatic stellate cell activation and liver fibrosis in rats. Am J Pathol (2009) 0.78
Anti-CD163-dexamethasone protects against apoptosis after ischemia/reperfusion injuries in the rat liver. Ann Med Surg (Lond) (2015) 0.78
Marginal copper deficiency increases liver neutrophil accumulation after ischemia/reperfusion in rats. Biol Trace Elem Res (2010) 0.77
Matrix metalloproteinase-9 in the initial injury after hepatectomy in mice. World J Gastroenterol (2013) 0.77
Chemokine Receptors, CXCR1 and CXCR2, Differentially Regulate Exosome Release in Hepatocytes. PLoS One (2016) 0.77
Tumor induced hepatic myeloid derived suppressor cells can cause moderate liver damage. PLoS One (2014) 0.77
CD44 disruption attenuates murine hepatic ischemia/reperfusion injury. J Korean Med Sci (2011) 0.77
Sivelestat sodium hydrate inhibits neutrophil migration to the vessel wall and suppresses hepatic ischemia-reperfusion injury. Dig Dis Sci (2013) 0.77
Expression patterns and action analysis of genes associated with physiological responses during rat liver regeneration: Innate immune response. World J Gastroenterol (2006) 0.77
Apoptotic-like tumor cells and apoptotic neutrophils in mitochondrion-rich gastric adenocarcinomas: a comparative study with light and electron microscopy between these two forms of cell death. Rare Tumors (2013) 0.76
Mathematical Model of Innate and Adaptive Immunity of Sepsis: A Modeling and Simulation Study of Infectious Disease. Biomed Res Int (2015) 0.76
Therapeutic targets for cholestatic liver injury. Expert Opin Ther Targets (2015) 0.76
Hypoxia sensitization of hepatocytes to neutrophil elastase-mediated cell death depends on MAPKs and HIF-1α. Am J Physiol Gastrointest Liver Physiol (2012) 0.76
Characterization of microparticles after hepatic ischemia-reperfusion injury. PLoS One (2014) 0.76
Some mechanisms of the protective effect of ischemic preconditioning on rat liver ischemia-reperfusion injury. Int J Gen Med (2014) 0.76
STAT3 does not regulate acute liver injury after ischemia/reperfusion. J Surg Res (2010) 0.76