Published in Cell Cycle on May 01, 2006
A dual phosphoinositide-3-kinase alpha/mTOR inhibitor cooperates with blockade of epidermal growth factor receptor in PTEN-mutant glioma. Cancer Res (2007) 2.62
PI3Kinase signaling in glioblastoma. J Neurooncol (2010) 1.01
Lipid rafts and caveolae in signaling by growth factor receptors. Open Biochem J (2007) 0.96
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat Med (2011) 6.85
Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. Proc Natl Acad Sci U S A (2005) 6.62
Oncogenic PI3K deregulates transcription and translation. Nat Rev Cancer (2005) 6.05
The let-7 microRNA reduces tumor growth in mouse models of lung cancer. Cell Cycle (2008) 4.95
Cancer-specific mutations in PIK3CA are oncogenic in vivo. Proc Natl Acad Sci U S A (2006) 4.84
Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34. Cancer Res (2010) 3.21
Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes. Mol Ther (2009) 2.92
Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice. Mol Ther (2011) 2.75
Triple layer control: phosphorylation, acetylation and ubiquitination of FOXO proteins. Cell Cycle (2005) 2.35
Cancer-specific mutations in phosphatidylinositol 3-kinase. Trends Biochem Sci (2007) 1.90
Mutated PI 3-kinases: cancer targets on a silver platter. Cell Cycle (2005) 1.16
Phosphatidylinositol 3-kinase: the oncoprotein. Curr Top Microbiol Immunol (2010) 1.14
Phosphoinositide 3-kinase: from viral oncoprotein to drug target. Virology (2006) 1.07
Quantification of therapeutic miRNA mimics in whole blood from nonhuman primates. Anal Chem (2014) 0.96
Applying small RNA molecules to the directed treatment of human diseases: realizing the potential. Expert Opin Ther Targets (2008) 0.94
Coordinate transcriptional repression of liver fatty acid-binding protein and microsomal triglyceride transfer protein blocks hepatic very low density lipoprotein secretion without hepatosteatosis. J Biol Chem (2006) 0.94
TP53-independent function of miR-34a via HDAC1 and p21(CIP1/WAF1.). Mol Ther (2013) 0.92
Requirement of phosphatidylinositol(3,4,5)trisphosphate in phosphatidylinositol 3-kinase-induced oncogenic transformation. Mol Cancer Res (2009) 0.86
Kinase inhibitors: vice becomes virtue. Cancer Cell (2006) 0.85
Microsomal triglyceride transfer protein is essential for hepatic secretion of apoB-100 and apoB-48 but not triglyceride. J Lipid Res (2002) 0.80
Jun: stealth, stability, and transformation. Mol Cell (2005) 0.78
TOJ3, a v-jun target with intrinsic oncogenic potential, is directly regulated by Jun via a novel AP-1 binding motif. Virology (2008) 0.75
A qRT-PCR Method for Determining the Biodistribution Profile of a miR-34a Mimic. Methods Mol Biol (2015) 0.75