PubRank

P C Zamecnik

Author PubWeight™ 122.67‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proc Natl Acad Sci U S A 1978 7.90
2 Medical Survey of Nutrition in Newfoundland. Can Med Assoc J 1945 5.51
3 Inhibition of replication and expression of human T-cell lymphotropic virus type III in cultured cells by exogenous synthetic oligonucleotides complementary to viral RNA. Proc Natl Acad Sci U S A 1986 5.18
4 Detection of nucleic acid hybridization by nonradiative fluorescence resonance energy transfer. Proc Natl Acad Sci U S A 1988 4.90
5 Rous sarcoma virus genome is terminally redundant: the 3' sequence. Proc Natl Acad Sci U S A 1977 4.79
6 Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide. Proc Natl Acad Sci U S A 1978 4.65
7 BINDING OF AMINO ACIDS TO THE END GROUP OF A SOLUBLE RIBONUCLEIC ACID. Proc Natl Acad Sci U S A 1959 3.40
8 Oligodeoxynucleoside phosphoramidates and phosphorothioates as inhibitors of human immunodeficiency virus. Proc Natl Acad Sci U S A 1988 2.98
9 Inhibition of human immunodeficiency virus replication by antisense oligodeoxynucleotides. Proc Natl Acad Sci U S A 1988 2.85
10 The 3'-terminal nucleosides of the high molecular weight RNA of avian myeloblastosis virus. Proc Natl Acad Sci U S A 1972 2.31
11 Presence of diadenosine 5',5''' -P1, P4-tetraphosphate (Ap4A) in mamalian cells in levels varying widely with proliferative activity of the tissue: a possible positive "pleiotypic activator". Proc Natl Acad Sci U S A 1976 2.29
12 Inhibition of human immunodeficiency virus in early infected and chronically infected cells by antisense oligodeoxynucleotides and their phosphorothioate analogues. Proc Natl Acad Sci U S A 1989 2.14
13 Inhibition of acquired immunodeficiency syndrome virus by oligodeoxynucleoside methylphosphonates. Proc Natl Acad Sci U S A 1988 2.09
14 Cupric ion catalysis in hydrolysis of aminoacyl-tRNA. Biochim Biophys Acta 1968 2.07
15 Enzymatic synthesis of diadenosine tetraphosphate and diadenosine triphosphate with a purified lysyl-sRNA synthetase. Biochem Biophys Res Commun 1966 2.02
16 Amino-acid acceptor activity of the "70S-associated" 4S RNA from avian myeloblastosis virus. Proc Natl Acad Sci U S A 1973 1.78
17 Isolation and characterization of dinucleoside tetra- and tri-phosphates formed in the presence of lysyl-sRNA synthetase. Biochem Biophys Res Commun 1966 1.70
18 Treatment of Mycobacterium tuberculosis with antisense oligonucleotides to glutamine synthetase mRNA inhibits glutamine synthetase activity, formation of the poly-L-glutamate/glutamine cell wall structure, and bacterial replication. Proc Natl Acad Sci U S A 2000 1.65
19 Thiosine-resistant mutants of Escherichia coli K-12 with growth-medium-dependent lysl-tRNA synthetase activity. I. Isolation and physiological characterization. Biochim Biophys Acta 1972 1.63
20 Base composition differences between avian myeloblastosis virus transfer RNA and transfer RNA isolated from host cells. Proc Natl Acad Sci U S A 1971 1.63
21 THE TOXIC FACTORS IN EXERIMENTAL TRAUMATIC SHOCK. VI. THE TOXIC INFLUENCE OF THE BACTERIAL FLORA, PARTICULARLY CLOSTRIDIUM WELCHII, IN EXUDATES OF ISCHEMIC MUSCLE. J Clin Invest 1945 1.54
22 THE TOXIC FACTORS IN EXPERIMENTAL TRAUMATIC SHOCK. IV. THE EFFECTS OF THE INTRAVENOUS INJECTION OF THE EFFUSION FROM ISCHEMIC MUSCLE. J Clin Invest 1945 1.54
23 Site-specific excision from RNA by RNase H and mixed-phosphate-backbone oligodeoxynucleotides. Proc Natl Acad Sci U S A 1990 1.50
24 Some physical properties of lysyl and arginyl-transfer RNA synthetases of Escherichia coli B. Biochim Biophys Acta 1969 1.50
25 THE TOXIC FACTORS IN EXPERIMENTAL TRAUMATIC SHOCK. I. PHYSIOLOGIC EFFECTS OF MUSCLE LIGATION IN THE DOG. J Clin Invest 1945 1.49
26 Evidence that the polyadenylic acid segment of "35S" RNA of avian myeloblastosis virus is located at the 3'-OH terminus. Biochem Biophys Res Commun 1973 1.38
27 PHYSIOLOGIC ACTION OF CLOSTRIDIUM OEDEMATIENS (NOVYI) TOXIN IN DOGS. J Clin Invest 1947 1.34
28 THE TOXIC FACTORS IN EXPERIMENTAL TRAUMATIC SHOCK. III. SHOCK ACCOMPANYING MUSCLE ISCHEMIA AND LOSS OF VASCULAR FLUID. J Clin Invest 1945 1.30
29 Analysis of oncornavirus RNA subunits by electron microscopy. Proc Natl Acad Sci U S A 1975 1.27
30 HeLa cell DNA polymerase alpha is tightly associated with tryptophanyl-tRNA synthetase and diadenosine 5',5"'-P1,P4-tetraphosphate binding activities. Proc Natl Acad Sci U S A 1981 1.27
31 Minor base composition of "70S-associated" 4S RNA from avian myeloblastosis virus. Proc Natl Acad Sci U S A 1973 1.26
32 Priming of DNA synthesis by diadenosine 5',5"'-P1,P4-tetraphosphate with a double-stranded octadecamer as a template and DNA polymerase alpha. Proc Natl Acad Sci U S A 1982 1.20
33 Incorporation of adenosine into ATP: formation of compartmentalized ATP. Proc Natl Acad Sci U S A 1976 1.19
34 An historical account of protein synthesis, with current overtones--a personalized view. Cold Spring Harb Symp Quant Biol 1969 1.17
35 Mutation of chloroplasts in Ageratum, following treatment with 5-bromodeoxyuridine. Exp Cell Res 1967 1.14
36 Some optical properties of diadenosine-5'-phosphates. Proc Natl Acad Sci U S A 1969 1.11
37 A tumor antigen in tissue cultures derived from patients with Hodgkin's disease. Proc Natl Acad Sci U S A 1973 1.09
38 An antigen in Hodgkin's disease tissue cultures: fluorescent antibody studies. Proc Natl Acad Sci U S A 1974 1.09
39 Conformational differences between s-RNA and aminoacyl s-RNA. Biochem Biophys Res Commun 1965 1.09
40 Regulation of DNA replication in S phase nuclei by ATP and ADP pools. Proc Natl Acad Sci U S A 1979 1.06
41 A new chemical procedure for 32P-labeling of ribonucleic acids at their 5'-ends after isolation. Proc Natl Acad Sci U S A 1975 1.03
42 Association of diadenosine 5',5"'-P1,P4-tetraphosphate binding protein with HeLa cell DNA polymerase alpha. J Biol Chem 1981 1.02
43 THE TOXIC FACTORS IN EXPERIMENTAL TRAUMATIC SHOCK. II. STUDIES ON ELECTROLYTE AND WATER BALANCE IN SHOCK. J Clin Invest 1945 1.01
44 P1,P4-dithio-P2,P3-monochloromethylene diadenosine 5',5'''-P1,P4-tetraphosphate: a novel antiplatelet agent. Proc Natl Acad Sci U S A 1997 1.00
45 Site specific functionalization of oligonucleotides for attaching two different reporter groups. Nucleic Acids Res 1990 1.00
46 An antigen in Hodgkin's disease tissue cultures: radioiodine-labeled antibody studies. Proc Natl Acad Sci U S A 1974 0.99
47 Tissue culture studies in Hodgkin's disease: Morphologic, cytogenetic, cell surface, and enzymatic properties of cultures derived from splenic tumors. J Exp Med 1977 0.99
48 Contamination of Hodgkin's disease cell cultures. Nature 1981 0.98
49 Inhibition of influenza virus replication by phosphorothioate oligodeoxynucleotides. Proc Natl Acad Sci U S A 1990 0.97
50 Antimycobacterial activities of antisense oligodeoxynucleotide phosphorothioates in drug-resistant strains. Proc Natl Acad Sci U S A 1996 0.96
51 Detection of inflamed atherosclerotic lesions with diadenosine-5',5'''-P1,P4-tetraphosphate (Ap4A) and positron-emission tomography. Proc Natl Acad Sci U S A 2006 0.95
52 Biological Synthesis of Radioactive Silk. Science 1949 0.94
53 Oligonucleotides with rapid turnover of the phosphate groups occur endogenously in eukaryotic cells. Proc Natl Acad Sci U S A 1987 0.94
54 5',5'''-P1, P4 diadenosine tetraphosphate (Ap4A): a putative initiator of DNA replication. Cancer Invest 1985 0.93
55 Relationship of the first step in protein synthesis to ppGpp: formation of A(5')ppp(5')Gpp. Proc Natl Acad Sci U S A 1975 0.93
56 Thiosine-resistant mutants of Escherichia coli K-12 with growth-medium-dependent lysyl-tRNA synthetase activity.II. Evidence for an altered lysyl-tRNA synthetase. Biochim Biophys Acta 1972 0.90
57 Conformational differences among purified samples of transfer RNA from yeast. Proc Natl Acad Sci U S A 1966 0.90
58 THE INFLUENCE OF ANTITOXIN UPON THE ACTION OF CLOSTRIDIUM OEDEMATIENS TOXIN IN THE HEART-LUNG PREPARATION OF THE DOG. J Clin Invest 1947 0.88
59 99mTc-labeled nucleotides as tumor-seeking radiodiagnostic agents. Proc Natl Acad Sci U S A 1984 0.86
60 Aspects of the kinetic properties of lysyl-tRNA synthetase from Escherichia coli, strain B. Biochim Biophys Acta 1970 0.86
61 Increased incorporation of adenosine into adenine nucleotide pools in serum-deprived mammalian cells. Proc Natl Acad Sci U S A 1978 0.85
62 Covalent modification of phenylalanyl-tRNA synthetase with phenylalanine during the amino acid activation reaction catalyzed by the enzyme. J Biol Chem 1985 0.85
63 A sensitive micro assay for inorganic pyrophosphatase. Anal Biochem 1970 0.84
64 The clearance and degradation of oligodeoxynucleotides following intravenous injection into rabbits. Antisense Res Dev 1991 0.83
65 Synthesis and anti-HIV activity of oligoribonucleotides and their phosphorothioate analogs. Ann N Y Acad Sci 1992 0.83
66 Growth of cultured cells from patients with Hodgkin's disease and transplantation into nude mice. Proc Natl Acad Sci U S A 1977 0.83
67 An in vivo effect of the metabolites L-alanine and glycyl-L-leucine on the properties of lysyl-tRNA synthetase from Escherichia coli K-12. I. Influence on subunit composition and molecular weight distribution. Biochim Biophys Acta 1976 0.83
68 Rapid noninvasive detection of experimental atherosclerotic lesions with novel 99mTc-labeled diadenosine tetraphosphates. Proc Natl Acad Sci U S A 1998 0.82
69 Ribosomes and protein synthesis. J Cell Biol 1981 0.81
70 The mechanism of protein synthesis and its possible alteration in the presence of oncogenic RNA viruses. Cancer Res 1966 0.80
71 Optical rotatory dispersion of E. coli sRNA in the far ultraviolet region. Biochem Biophys Res Commun 1965 0.80
72 Summary of symposium on transfer RNA and transfer RNA modification in differentiation and neoplasia. Cancer Res 1971 0.79
73 Electron microscopy of Hodgkin's disease tissue cultures. Cancer 1979 0.78
74 Chromatographic and electrophoretic analysis of an antigen in Hodgkin's disease tissue cultures. J Natl Cancer Inst 1977 0.78
75 Conjugates of minor groove DNA binders with oligodeoxynucleotides: synthesis and properties. Antisense Nucleic Acid Drug Dev 1996 0.78
76 Diadenosine 5',5'''-p1,p4-tetraphosphate deficiency in blood platelets of the Chédiak-Higashi syndrome. Blood 1985 0.77
77 The mechanism of amino acid activation: the work of Mahlon Hoagland. 1956. J Biol Chem 2009 0.75
78 Action of osmium tetroxide on amino acid-transfer ribonucleic acid: correlations between the genetic code and the sensitivity of acceptor activity. Biochem J 1966 0.75
79 Aminoacyl-tRNA synthetases catalyze AMP----ADP----ATP exchange reactions, indicating labile covalent enzyme-amino-acid intermediates. Proc Natl Acad Sci U S A 1987 0.75
80 Proton magnetic resonance investigation of interactions between L-tryptophan and dinucleoside phosphates at low pD. Biopolymers 1977 0.75
81 Historical aspects of protein synthesis. Ann N Y Acad Sci 1979 0.75
82 Joseph Charles Aub 1890-1973. Trans Assoc Am Physicians 1974 0.75
83 Similarities in ATP-binding domain between E. coli tyrosyl-tRNA synthetase and human estrogen receptor. FASEB J 1989 0.75
84 Chemical modification of aminoacyl ligases and the effect on formation of aminoacyl-tRNA. Biochim Biophys Acta 1967 0.75
85 Diagnosis of storage pool deficiency by determination of diadenosine 5', 5'''-P1,P4-tetraphosphate in whole blood. Thromb Res 1986 0.75
86 Intermediate reactions in protein biosynthesis. 1957. Biochim Biophys Acta 1989 0.75
87 Minor base changes in transfer ribonucleic acid in avian myeloblastosis virus. Bibl Haematol 1973 0.75