Published in J Clin Invest on September 01, 1949
Study of theophylline plasma levels after oral administration of new theophylline compounds. Br Med J (1957) 2.71
The use of aminophylline by inhalation. Br J Clin Pharmacol (1982) 0.78
Aminophylline suppresses stress-induced visceral hypersensitivity and defecation in irritable bowel syndrome. Sci Rep (2017) 0.75
THE ACTION OF HISTAMINE ON THE RESPIRATORY TRACT IN NORMAL AND ASTHMATIC SUBJECTS. J Clin Invest (1946) 6.72
EVALUATION OF THERAPEUTIC SUBSTANCES EMPLOYED FOR THE RELIEF OF BRONCHOSPASM. V. ADRENERGIC AGENTS. J Clin Invest (1949) 3.43
COMPARATIVE ACTION OF ACETYL-BETA-METHYL CHOLINE AND HISTAMINE ON THE RESPIRATORY TRACT IN NORMALS, PATIENTS WITH HAY FEVER, AND SUBJECTS WITH BRONCHIAL ASTHMA. J Clin Invest (1947) 2.81
EVALUATION OF THERAPEUTIC SUBSTANCES EMPLOYED FOR THE RELIEF OF BRONCHOSPASM. V. ADRENERGIC AGENTS. J Clin Invest (1949) 3.43
A system in mouse liver for the repair of O6-methylguanine lesions in methylated DNA. Nucleic Acids Res (1981) 1.56
Inhibitory effect of apigenin, a plant flavonoid, on epidermal ornithine decarboxylase and skin tumor promotion in mice. Cancer Res (1990) 1.24
Morphological and biochemical studies of isolated mitochondria from fetal, neonatal, and adult liver and from neoplastic tissues. J Cell Biol (1967) 1.21
Properties of deoxythymidine kinase partially purified from animal tumors. J Biol Chem (1965) 1.20
Rates of turnover of deoxythymidine kinase and of its template RNA in regenerating and control liver. Cancer Res (1967) 1.12
O6-methylguanine methyltransferase in rat liver. Biochemistry (1983) 1.09
Effects of crocidolite and chrysotile asbestos on cellular uptake and metabolism of benzo(a)pyrene in hamster tracheal epithelial cells. Environ Health Perspect (1983) 1.06
Inhibition of thymidine kinase activity in liver and hepatomas by TTP and d-CTP. Biochem Biophys Res Commun (1964) 1.05
Glycine N-methyltransferase is an example of functional diversity. Role as a polycyclic aromatic hydrocarbon-binding receptor. J Biol Chem (1997) 1.01
Influence of asbestos on the uptake of benzo(a)pyrene and DNA alkylation in hamster tracheal epithelial cells. Cancer Res (1983) 0.99
DNA-mediated transfer and expression of a human DNA repair gene that demethylates O6-methylguanine. Mol Cell Biol (1985) 0.98
Kinetic and DNA-binding properties of recombinant human O6-methylguanine-DNA methyltransferase. Arch Biochem Biophys (1993) 0.98
Expression of human O6-methylguanine-DNA methyltransferase in a DNA excision repair-deficient Chinese hamster ovary cell line and its response to certain alkylating agents. Cancer Res (1992) 0.97
Increased activity of enzymes for de novo pyrimidine biosynthesis after orotic acid administration. Mol Pharmacol (1968) 0.95
ATP depletion affects the phosphorylation state, ligand binding, and nuclear transport of the 4 S polycyclic aromatic hydrocarbon-binding protein in rat hepatoma cells. J Biol Chem (1996) 0.93
Effects of 5-trifluoromethyldeoxyuridine upon deoxythymidine kinase. Biochem Pharmacol (1967) 0.91
Formation and removal of benzo(a)pyrene adducts of DNA in hamster tracheal epithelial cells. Cancer Res (1981) 0.91
Multiple, immunoidentical forms of phenobarbital-induced rat liver cytochromes P-450 are encoded by different mRNAs. J Biol Chem (1982) 0.91
Benzypyrene hydroxylase activity in isolated parenchymal and nonparenchymal cells of rat liver. J Cell Biol (1972) 0.90
Anti-mutagenesis and anti-promotion by apigenin, robinetin and indole-3-carbinol. Carcinogenesis (1986) 0.90
Differences in thymidine kinase-inducing ability of herpesvirus types 1 and 2. Virology (1971) 0.89
Rat liver cytosolic 4 S polycyclic aromatic hydrocarbon-binding protein is glycine N-methyltransferase. J Biol Chem (1994) 0.88
Activities of enzymes of deoxyribonucleic acid synthesis after unilateral nephrectomy. Cancer Res (1967) 0.88
Regulation of the constitutive expression of the human CYP1A2 gene: cis elements and their interactions with proteins. Mol Pharmacol (1995) 0.87
Administration of 3-methylcholanthrene to rats increases the specific hybridizable mRNA coding for cytochrome P-450c. Proc Natl Acad Sci U S A (1981) 0.87
Irradiation-induced expression of O6-methylguanine-DNA methyltransferase in mammalian cells. Cancer Res (1992) 0.87
Aspartate carbamoyltransferase from rat liver. Biochem J (1966) 0.86
Gene structure and nucleotide sequence for rat cytochrome P-450c. Arch Biochem Biophys (1985) 0.86
Early differential effects of 3-methylcholanthrene and its "K-region" epoxide on mouse skin. Possible implication in the two-stage mechanism of tumorigenesis. J Natl Cancer Inst (1974) 0.86
Ribonuclease activity in hepatic nuclei during development. Biochim Biophys Acta (1966) 0.86
Thymidine kinase activity in cells abortively and productively infected with human adenoviruses. Virology (1968) 0.86
Effects of phenobarbital and 3-methylcholanthrene administration on glutathione-S-epoxide transferase activity in rat liver. Biochem Pharmacol (1976) 0.85
Colon carcinogenesis: an overview. Cancer (1980) 0.85
Effect of phenobarbital and 3-methylcholanthrene administration on epoxide hydrase levels in liver microsomes. Biochem Pharmacol (1977) 0.85
Activities of enzymes of pyrimidine nucleotide synthesis in slowly growing kidney tumors. Cancer Res (1969) 0.85
Inhibition of human O6-methylguanine-DNA methyltransferase by 5-methylcytosine. Cancer Res (1994) 0.84
Mouse liver and lung glutathione s-epoxide transferase: effects of phenobarbital and 3-methylcholanthrene administration. Chem Biol Interact (1976) 0.84
The distribution of radioactivity within the hepatic cell after administration of labeled 3-methylcholanthrene. Cancer Res (1967) 0.84
Enzyme patterns in a group of transplantable mouse hepatomas of different growth rates. Cancer Res (1971) 0.83
The identity and nuclear uptake of a cytosolic binding protein for 3-methylcholanthrene. Arch Biochem Biophys (1980) 0.83
Regulatory control of pyrimidine biosynthesis in mammalian systems. Adv Enzyme Regul (1964) 0.83
Synthesis of liver cytochrome P-450b in a cell-free protein synthesizing system. Biochem Biophys Res Commun (1979) 0.83
Ribonucleic acid polymerase activity in liver nuclei from rats pretreated with 3-methylcholanthrene. Mol Pharmacol (1966) 0.83
Glutathione-S-epoxide transferase activity during development and the effect of partial hepatectomy. Cancer Res (1976) 0.83
Northern hybridization analysis of RNA using diethylpyrocarbonate-treated nonfat milk. Anal Biochem (1986) 0.83
Rates of turnover of deoxythymidine kinase and of its template RNA in Novikoff hepatoma and neonatal liver. Cancer Res (1970) 0.82
Glutathione-S-epoxide transferase in mouse skin and human foreskin. J Invest Dermatol (1976) 0.82
Microsomal N-demethylase activity in developing rat liver after administration of 3-methylcholanthrene. Biochem Pharmacol (1968) 0.82
Comparison of in vivo and in vitro binding of polycyclic hydrocarbons to DNA. Chem Biol Interact (1978) 0.82
Hepatic epoxide hydrase in neonatal and partially hepatectomized rats. Cancer Res (1974) 0.82
The molecular cloning of cytochrome P-450c information. Arch Biochem Biophys (1981) 0.82
Histone modification in liver after administration of inducers of mixed function oxidase activity. Chem Biol Interact (1975) 0.82
Epidermal prostaglandins after topical application of a tumor promotor. Cancer Lett (1979) 0.82
Glycine N-methyltransferase is a mediator of cytochrome P4501A1 gene expression. Arch Biochem Biophys (1995) 0.81
The significance of DNA cross-linking to cis-diamminedichloroplatinum(II)-induced cytotoxicity in sensitive and resistant lines of murine leukemia L1210 cells. Chem Biol Interact (1982) 0.81
Retrovirus-mediated transfer of the human O6-methylguanine-DNA methyltransferase gene into a murine hematopoietic stem cell line and resistance to the toxic effects of certain alkylating agents. Biochem Pharmacol (1996) 0.81
Binding characteristics of 4S PAH-binding protein and Ah receptor from rats and mice. J Toxicol Environ Health (1990) 0.81
Hepatic cytochrome P-448 and epoxide hydrase: enzymes of nuclear origin are immunochemically identical with those of microsomal origin. Arch Biochem Biophys (1979) 0.81
Effects of phenobarbital on the phosphorylation of acidic nuclear proteins of rat liver. Biochim Biophys Acta (1974) 0.81
The role of counseling in infertility. Fertil Steril (1979) 0.81
Rat CYP1A1 negative regulatory element: biological activity and interaction with a protein from liver and hepatoma cells. Mol Pharmacol (1993) 0.80
Analysis of within-subject variation of caffeine metabolism when used to determine cytochrome P4501A2 and N-acetyltransferase-2 activities. Cancer Epidemiol Biomarkers Prev (1995) 0.80
Glucocorticoid regulation of the rat cytochrome P450c (P450IA1) gene: receptor binding within intron I. Arch Biochem Biophys (1989) 0.80
Effects of 3-methylcholanthrene administration on the proteins of endoplasmic reticulum. Biochem Pharmacol (1971) 0.80
Nuclear aryl hydrocarbon hydroxylase and interaction of polycyclic hydrocarbons with nuclear components. Arch Biochem Biophys (1977) 0.80
Activation of genetic transcription in rat liver chromatin by 3-methylcholanthrene. Mol Pharmacol (1969) 0.80
Ribonucleic acid biosynthesis in methylcholanthrene-treated rats. Biochim Biophys Acta (1966) 0.80
Characterization of the expression products of recombinant human choriogonadotropin and subunits. J Biol Chem (1987) 0.80
Induction and purification of O6-methylguanine-DNA-methyltransferase from rat liver. Carcinogenesis (1990) 0.80
Malignant transformation of cultured rat hepatocytes by (+)- and (-)-trans-7,8-dihydro-7,8-dihydroxybenzo(a)pyrene. Cancer Res (1980) 0.80
Polyribosomal patterns in rat liver after the administration of 3-methylcholanthrene. Biochim Biophys Acta (1966) 0.79
Differences in the binding of 3-methylcholanthrene and phenobarbital to rat liver cytosolic and nuclear protein fractions. Arch Biochem Biophys (1981) 0.79
The homodimeric form of glycine N-methyltransferase acts as a polycyclic aromatic hydrocarbon-binding receptor. Biochemistry (1997) 0.79
Epidermal hyperplasia after topical application of benzo (a) pyrene, benzo (a) pyrene diol epoxides, and other metabolites. Cancer Res (1977) 0.79
Effects of an epoxide hydrase inhibitor on in vivo binding of polycyclic hydrocarbons to DNA and on skin carcinogenesis. J Natl Cancer Inst (1974) 0.79
Oct-1 transcription factor is a negative regulator of rat CYP1A1 expression via an octamer sequence in its negative regulatory element. Mol Pharmacol (1996) 0.79
Induction of aryl hydrocarbon hydroxylase in mouse tissues from a high and low cancer strain and their F 1 hybrids. J Natl Cancer Inst (1973) 0.78
Asbestos and benzo[a]pyrene act synergistically to induce squamous metaplasia and incorporation of [3H]thymidine in hamster tracheal epithelium. Carcinogenesis (1984) 0.78
Induction of cytochromes P450IA1 and P450IA2 as determined by solution hybridization. Biochem Pharmacol (1991) 0.78
Correlation of induction of aryl hydrocarbon hydroxylase in cultured rat hepatocytes with saturable high-affinity binding of 3-methylcholanthrene to a 4S cytoplasmic protein. Cancer Res (1981) 0.78
The isolation and characterization of specific 3-methylcholanthrene-binding proteins from rat liver cytosol. Arch Biochem Biophys (1983) 0.78
Nuclear transcription factor Oct-1 binds to the 5'-upstream region of CYP1A1 and negatively regulates its expression. Int J Biochem Cell Biol (1996) 0.78
Persistent binding of 3-methylcholanthrene to mouse lung DNA and its correlation with susceptibility to pulmonary neoplasia. Cancer Res (1979) 0.78
Phospholipase activity in skin after application of phorbol esters and 3-methylcholanthrene. Carcinogenesis (1981) 0.78
The effect of isoproterenol on pyrimidine biosynthesis in the salivary gland and heart of rats. Proc Soc Exp Biol Med (1968) 0.78
Further characterization of the polycyclic aromatic hydrocarbon binding properties of the 4S protein. Arch Biochem Biophys (1986) 0.78
Deoxythymidine kinase in regenerating rat liver. Methods Enzymol (1978) 0.78
Enhanced pancreatic and skin tumorigenesis in cabbage-fed hamsters and mice. Carcinogenesis (1987) 0.78
Ontogenetic changes of proteins of endoplasmic reticulum. J Cell Biol (1972) 0.78
Molecular induction by phenobarbital of a rat hepatic form of cytochrome P-450: expression of a 4-kilobase messenger RNA. Arch Biochem Biophys (1983) 0.78
Gas chromatographic assay of epoxide hydrase activity with 3-methylcholanthrene-11,12-oxide. Science (1973) 0.78
Effect of 3-methylcholanthrene administration on hepatic ribonucleic acid polymerase activities. Chem Biol Interact (1981) 0.78
Alkylation of mammalian cell DNA, persistence of adducts, and relationship to carcinogenesis. Drug Metab Rev (1982) 0.78
Enhanced initiation factor activity in rats after administration of 3-methylcholanthrene or -naphthoflavone. Res Commun Chem Pathol Pharmacol (1972) 0.77
Expression of human O6-methylguanine-DNA methyltransferase in Chinese hamster ovary cells and restoration of cellular resistance to certain N-nitroso compounds. Mol Carcinog (1991) 0.77
Induction of cytochrome P450 by xenobiotics. Pharmacol Rev (1984) 0.77
3-Methylcholanthrene-induced expression of the cytochrome P-450c gene. Arch Biochem Biophys (1985) 0.77
Epoxide hydrase activity in liver nuclei: hydration of benzo[a]pyrene-4,5-oxide and styrene oxide. Chem Biol Interact (1978) 0.77