Published in Circ Res on May 18, 2006
Kinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparks. Circ Res (2010) 2.29
The cAMP binding protein Epac modulates Ca2+ sparks by a Ca2+/calmodulin kinase signalling pathway in rat cardiac myocytes. J Physiol (2007) 1.85
Ryanodine receptor phosphorylation at Serine 2030, 2808 and 2814 in rat cardiomyocytes. Biochem Biophys Res Commun (2008) 1.57
Ryanodine receptor structure: progress and challenges. J Biol Chem (2008) 1.29
Increased Ca(2+) leak and spatiotemporal coherence of Ca(2+) release in cardiomyocytes during beta-adrenergic stimulation. J Physiol (2009) 1.22
Ca2+/calmodulin kinase II increases ryanodine binding and Ca2+-induced sarcoplasmic reticulum Ca2+ release kinetics during beta-adrenergic stimulation. J Mol Cell Cardiol (2007) 1.18
Caveolae compartmentalise β2-adrenoceptor signals by curtailing cAMP production and maintaining phosphatase activity in the sarcoplasmic reticulum of the adult ventricular myocyte. J Mol Cell Cardiol (2011) 1.10
Dysregulated sarcoplasmic reticulum calcium release: potential pharmacological target in cardiac disease. Pharmacol Ther (2008) 1.09
Ryanodine receptor-mediated arrhythmias and sudden cardiac death. Pharmacol Ther (2009) 1.08
Role of RyR2 phosphorylation in heart failure and arrhythmias: Controversies around ryanodine receptor phosphorylation in cardiac disease. Circ Res (2014) 1.06
Beta-adrenergic signaling accelerates and synchronizes cardiac ryanodine receptor response to a single L-type Ca2+ channel. Proc Natl Acad Sci U S A (2009) 1.06
PKA phosphorylation of cardiac ryanodine receptor modulates SR luminal Ca2+ sensitivity. J Mol Cell Cardiol (2012) 1.01
Genetic ablation of ryanodine receptor 2 phosphorylation at Ser-2808 aggravates Ca(2+)-dependent cardiomyopathy by exacerbating diastolic Ca2+ release. J Physiol (2014) 0.99
Regulation of cardiac excitation and contraction by p21 activated kinase-1. Prog Biophys Mol Biol (2009) 0.99
Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation. Cardiovasc Res (2014) 0.92
Is ryanodine receptor phosphorylation key to the fight or flight response and heart failure? J Clin Invest (2010) 0.91
Integrins protect cardiomyocytes from ischemia/reperfusion injury. J Clin Invest (2013) 0.90
Ryanodine receptor phosphorylation and heart failure: phasing out S2808 and "criminalizing" S2814. Circ Res (2012) 0.90
Mechanisms of beta-adrenergic modulation of I(Ks) in the guinea-pig ventricle: insights from experimental and model-based analysis. Biophys J (2009) 0.89
CaMKII regulation of cardiac ryanodine receptors and inositol triphosphate receptors. Front Pharmacol (2014) 0.89
Single-channel characterization of the rabbit recombinant RyR2 reveals a novel inactivation property of physiological concentrations of ATP. J Membr Biol (2008) 0.88
ß-Adrenergic stimulation increases RyR2 activity via intracellular Ca2+ and Mg2+ regulation. PLoS One (2013) 0.86
Ca²+-dependent phosphorylation of RyR2 can uncouple channel gating from direct cytosolic Ca²+ regulation. J Membr Biol (2011) 0.86
Regulation of Ryanodine Receptor Ion Channels Through Posttranslational Modifications. Curr Top Membr (2010) 0.84
Alterations in the calcium homeostasis of skeletal muscle from postmyocardial infarcted rats. Pflugers Arch (2007) 0.76
Regulation of sarcoplasmic reticulum Ca(2+) release by serine-threonine phosphatases in the heart. J Mol Cell Cardiol (2016) 0.75
The effect of PKA-mediated phosphorylation of ryanodine receptor on SR Ca(2+) leak in ventricular myocytes. J Mol Cell Cardiol (2017) 0.75
Dysregulated Zn(2+) homeostasis impairs cardiac type-2 ryanodine receptor and mitsugumin 23 functions, leading to sarcoplasmic reticulum Ca(2+) leakage. J Biol Chem (2017) 0.75
Stoichiometric phosphorylation of cardiac ryanodine receptor on serine 2809 by calmodulin-dependent kinase II and protein kinase A. J Biol Chem (2003) 2.04
TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+. J Biol Chem (2010) 1.74
Caveolae compartmentalise β2-adrenoceptor signals by curtailing cAMP production and maintaining phosphatase activity in the sarcoplasmic reticulum of the adult ventricular myocyte. J Mol Cell Cardiol (2011) 1.10
Charade of the SR K+-channel: two ion-channels, TRIC-A and TRIC-B, masquerade as a single K+-channel. Biophys J (2010) 0.99
TRIC-B channels display labile gating: evidence from the TRIC-A knockout mouse model. Pflugers Arch (2013) 0.95
Myotoxic effects of clenbuterol in the rat heart and soleus muscle. J Appl Physiol (1985) (2002) 0.95
Functional regulation of the cardiac ryanodine receptor by suramin and calmodulin involves multiple binding sites. Mol Pharmacol (2004) 0.92
DIDS modifies the conductance, gating, and inactivation mechanisms of the cardiac ryanodine receptor. Biophys J (2002) 0.92
Localised Ca channel phosphorylation modulates the distribution of L-type Ca current in cardiac myocytes. J Mol Cell Cardiol (2010) 0.89
Single-channel characterization of the rabbit recombinant RyR2 reveals a novel inactivation property of physiological concentrations of ATP. J Membr Biol (2008) 0.88
FKBP12 activates the cardiac ryanodine receptor Ca2+-release channel and is antagonised by FKBP12.6. PLoS One (2012) 0.87
TRIC channels supporting efficient Ca(2+) release from intracellular stores. Pflugers Arch (2012) 0.87
Ca²+-dependent phosphorylation of RyR2 can uncouple channel gating from direct cytosolic Ca²+ regulation. J Membr Biol (2011) 0.86
Annexin A6 at the cardiac myocyte sarcolemma--evidence for self-association and binding to actin. Cell Biol Int (2008) 0.85
Characterisation of isoprenaline myotoxicity on slow-twitch skeletal versus cardiac muscle. Int J Cardiol (2002) 0.84
Removal of clustered positive charge from dihydropyridine receptor II-III loop peptide augments activation of ryanodine receptors. Biochem Biophys Res Commun (2004) 0.79
From eggs to hearts: what is the link between cyclic ADP-ribose and ryanodine receptors? Cardiovasc Ther (2010) 0.79
Critical evaluation of cardiac Ca2+-ATPase phosphorylation on serine 38 using a phosphorylation site-specific antibody. J Biol Chem (2004) 0.79
Structural characteristics that govern binding to, and modulation through, the cardiac ryanodine receptor nucleotide binding site. Mol Pharmacol (2003) 0.79
Minimal F-actin cytoskeletal system for planar supported phospholipid bilayers. Langmuir (2008) 0.78
Inhibition of cAMP-dependent protein kinase under conditions occurring in the cardiac dyad during a Ca2+ transient. Biophys J (2006) 0.77
Ca2+-calmodulin increases RyR2 open probability yet reduces ryanoid association with RyR2. Biophys J (2009) 0.77
Mitsugumin 23 forms a massive bowl-shaped assembly and cation-conducting channel. Biochemistry (2011) 0.77
Self-assembly of actin scaffolds at ponticulin-containing supported phospholipid bilayers. Biophys J (2005) 0.76