Published in Curr Opin Struct Biol on May 18, 2006
Interactome3D: adding structural details to protein networks. Nat Methods (2012) 1.89
Targeting the human cancer pathway protein interaction network by structural genomics. Mol Cell Proteomics (2008) 1.54
Reuse of structural domain-domain interactions in protein networks. BMC Bioinformatics (2007) 1.19
iAlign: a method for the structural comparison of protein-protein interfaces. Bioinformatics (2010) 1.17
The impact of extremophiles on structural genomics (and vice versa). Extremophiles (2007) 1.11
Identification of ligand templates using local structure alignment for structure-based drug design. J Chem Inf Model (2012) 0.87
Recognizing protein-protein interfaces with empirical potentials and reduced amino acid alphabets. BMC Bioinformatics (2007) 0.81
On the analysis of protein-protein interactions via knowledge-based potentials for the prediction of protein-protein docking. Protein Sci (2011) 0.80
Computational approaches to selecting and optimising targets for structural biology. Methods (2011) 0.77
Proteome survey reveals modularity of the yeast cell machinery. Nature (2006) 20.77
Potential artefacts in protein-interaction networks. FEBS Lett (2002) 2.24
3did: interacting protein domains of known three-dimensional structure. Nucleic Acids Res (2005) 2.18
Unveiling the role of network and systems biology in drug discovery. Trends Pharmacol Sci (2010) 2.06
A structural perspective on protein-protein interactions. Curr Opin Struct Biol (2004) 1.98
Interactome3D: adding structural details to protein networks. Nat Methods (2012) 1.89
A network medicine approach to human disease. FEBS Lett (2009) 1.83
3did: identification and classification of domain-based interactions of known three-dimensional structure. Nucleic Acids Res (2010) 1.71
3did Update: domain-domain and peptide-mediated interactions of known 3D structure. Nucleic Acids Res (2008) 1.51
Contextual specificity in peptide-mediated protein interactions. PLoS One (2008) 1.37
Structural insights into the target specificity of plant invertase and pectin methylesterase inhibitory proteins. Plant Cell (2004) 1.33
Targeting and tinkering with interaction networks. Nat Chem Biol (2008) 1.27
Ribonucleotide reductases: divergent evolution of an ancient enzyme. J Mol Evol (2002) 1.26
Pushing structural information into the yeast interactome by high-throughput protein docking experiments. PLoS Comput Biol (2009) 1.22
Three-dimensional modeling of protein interactions and complexes is going 'omics. Curr Opin Struct Biol (2011) 1.21
Towards a detailed atlas of protein-protein interactions. Curr Opin Struct Biol (2013) 1.19
3did: a catalog of domain-based interactions of known three-dimensional structure. Nucleic Acids Res (2013) 1.14
Dynamic interactions of proteins in complex networks: a more structured view. FEBS J (2009) 1.13
Interactome mapping suggests new mechanistic details underlying Alzheimer's disease. Genome Res (2010) 1.02
Novel peptide-mediated interactions derived from high-resolution 3-dimensional structures. PLoS Comput Biol (2010) 1.02
Systematic searches for molecular synapomorphies in model metazoan genomes give some support for Ecdysozoa after accounting for the idiosyncrasies of Caenorhabditis elegans. Evol Dev (2004) 1.01
Analysis of chemical and biological features yields mechanistic insights into drug side effects. Chem Biol (2013) 1.00
Uncovering new substrates for Aurora A kinase. EMBO Rep (2010) 1.00
Recycling side-effects into clinical markers for drug repositioning. Genome Med (2012) 0.99
Approved drug mimics of short peptide ligands from protein interaction motifs. J Chem Inf Model (2008) 0.98
Towards a molecular characterisation of pathological pathways. FEBS Lett (2008) 0.96
The role of structural disorder in the rewiring of protein interactions through evolution. Mol Cell Proteomics (2012) 0.95
The proton-pump inhibitor lansoprazole enhances amyloid beta production. PLoS One (2013) 0.91
NetAligner--a network alignment server to compare complexes, pathways and whole interactomes. Nucleic Acids Res (2012) 0.90
A novel framework for the comparative analysis of biological networks. PLoS One (2012) 0.89
Exploiting gene deletion fitness effects in yeast to understand the modular architecture of protein complexes under different growth conditions. BMC Syst Biol (2009) 0.86
A second-generation protein-protein interaction network of Helicobacter pylori. Mol Cell Proteomics (2014) 0.86
A systematic study of the energetics involved in structural changes upon association and connectivity in protein interaction networks. Structure (2011) 0.83
Functional and structural analysis of C-terminal BRCA1 missense variants. PLoS One (2013) 0.82
From protein interaction networks to novel therapeutic strategies. IUBMB Life (2012) 0.82
Incorporating high-throughput proteomics experiments into structural biology pipelines: identification of the low-hanging fruits. Proteomics (2008) 0.82
Systematic bioinformatics and experimental validation of yeast complexes reduces the rate of attrition during structural investigations. Structure (2010) 0.82
Structural systems pharmacology: the role of 3D structures in next-generation drug development. Chem Biol (2013) 0.81
On the analysis of protein-protein interactions via knowledge-based potentials for the prediction of protein-protein docking. Protein Sci (2011) 0.80
A molecular interpretation of genetic interactions in yeast. FEBS Lett (2008) 0.79
Structural similarity to bridge sequence space: finding new families on the bridges. Protein Sci (2005) 0.79
Yeast mitochondrial protein-protein interactions reveal diverse complexes and disease-relevant functional relationships. J Proteome Res (2015) 0.78
Revealing the molecular relationship between type 2 diabetes and the metabolic changes induced by a very-low-carbohydrate low-fat ketogenic diet. Nutr Metab (Lond) (2010) 0.77
Predicting protein-protein interaction specificity through the integration of three-dimensional structural information and the evolutionary record of protein domains. Mol Biosyst (2010) 0.76
Discovery and hypothesis generation through bioinformatics. Genome Biol (2006) 0.75