| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Homozygous mutations in ADAMTS10 and ADAMTS17 cause lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature.
|
Am J Hum Genet
|
2009
|
1.73
|
|
2
|
Role of phosphatidylinositol 3'-kinase/AKT pathway in diffuse large B-cell lymphoma survival.
|
Blood
|
2006
|
1.70
|
|
3
|
Clinicopathological analysis of papillary thyroid cancer with PIK3CA alterations in a Middle Eastern population.
|
J Clin Endocrinol Metab
|
2007
|
1.63
|
|
4
|
FREM1 mutations cause bifid nose, renal agenesis, and anorectal malformations syndrome.
|
Am J Hum Genet
|
2009
|
1.41
|
|
5
|
Genome-wide expression analysis of Middle Eastern colorectal cancer reveals FOXM1 as a novel target for cancer therapy.
|
Am J Pathol
|
2011
|
1.25
|
|
6
|
HER2, TOP2A, CCND1, EGFR and C-MYC oncogene amplification in colorectal cancer.
|
J Clin Pathol
|
2006
|
1.24
|
|
7
|
Prognostic significance of alterations in KRAS isoforms KRAS-4A/4B and KRAS mutations in colorectal carcinoma.
|
J Pathol
|
2009
|
1.19
|
|
8
|
Cyclooxygenase-2 inhibition inhibits PI3K/AKT kinase activity in epithelial ovarian cancer.
|
Int J Cancer
|
2010
|
1.17
|
|
9
|
High prevalence of fatty acid synthase expression in colorectal cancers in Middle Eastern patients and its potential role as a therapeutic target.
|
Am J Gastroenterol
|
2009
|
1.15
|
|
10
|
PIK3CA alterations in Middle Eastern ovarian cancers.
|
Mol Cancer
|
2009
|
1.11
|
|
11
|
Overexpression of leptin receptor predicts an unfavorable outcome in Middle Eastern ovarian cancer.
|
Mol Cancer
|
2009
|
1.05
|
|
12
|
Mutations in C2orf37, encoding a nucleolar protein, cause hypogonadism, alopecia, diabetes mellitus, mental retardation, and extrapyramidal syndrome.
|
Am J Hum Genet
|
2008
|
1.05
|
|
13
|
Fatty acid synthase and AKT pathway signaling in a subset of papillary thyroid cancers.
|
J Clin Endocrinol Metab
|
2008
|
1.05
|
|
14
|
A missense mutation in PIK3R5 gene in a family with ataxia and oculomotor apraxia.
|
Hum Mutat
|
2011
|
1.02
|
|
15
|
Frequent PIK3CA gene amplification and its clinical significance in colorectal cancer.
|
J Pathol
|
2009
|
1.01
|
|
16
|
Inhibition of c-MET is a potential therapeutic strategy for treatment of diffuse large B-cell lymphoma.
|
Lab Invest
|
2010
|
1.01
|
|
17
|
Bortezomib (Velcade) induces p27Kip1 expression through S-phase kinase protein 2 degradation in colorectal cancer.
|
Cancer Res
|
2008
|
0.99
|
|
18
|
Leptin-R and its association with PI3K/AKT signaling pathway in papillary thyroid carcinoma.
|
Endocr Relat Cancer
|
2010
|
0.99
|
|
19
|
HGF/c-Met pathway has a prominent role in mediating antiapoptotic signals through AKT in epithelial ovarian carcinoma.
|
Lab Invest
|
2010
|
0.97
|
|
20
|
Inhibition of fatty acid synthase suppresses c-Met receptor kinase and induces apoptosis in diffuse large B-cell lymphoma.
|
Mol Cancer Ther
|
2010
|
0.95
|
|
21
|
Overexpression of FoxM1 offers a promising therapeutic target in diffuse large B-cell lymphoma.
|
Haematologica
|
2012
|
0.91
|
|
22
|
Bortezomib-mediated expression of p27Kip1 through S-phase kinase protein 2 degradation in epithelial ovarian cancer.
|
Lab Invest
|
2009
|
0.90
|
|
23
|
Colorectal cancer risk is not associated with increased levels of homozygosity in Saudi Arabia.
|
Genet Med
|
2012
|
0.90
|
|
24
|
FoxM1 and its association with matrix metalloproteinases (MMP) signaling pathway in papillary thyroid carcinoma.
|
J Clin Endocrinol Metab
|
2011
|
0.88
|
|
25
|
Polymorphisms of drug-metabolizing enzymes CYP1A1, GSTT and GSTP contribute to the development of diffuse large B-cell lymphoma risk in the Saudi Arabian population.
|
Leuk Lymphoma
|
2008
|
0.87
|
|
26
|
c-Met inhibitor synergizes with tumor necrosis factor-related apoptosis-induced ligand to induce papillary thyroid carcinoma cell death.
|
Mol Med
|
2012
|
0.87
|
|
27
|
Demethylation of TMS1 gene sensitizes thyroid cancer cells to TRAIL-induced apoptosis.
|
J Clin Endocrinol Metab
|
2010
|
0.86
|
|
28
|
Leptin receptor expression and its association with PI3K/AKT signaling pathway in diffuse large B-cell lymphoma.
|
Leuk Lymphoma
|
2010
|
0.86
|
|
29
|
Overexpression of fatty acid synthase in Middle Eastern epithelial ovarian carcinoma activates AKT and Its inhibition potentiates cisplatin-induced apoptosis.
|
Mol Med
|
2011
|
0.84
|
|
30
|
Genetic polymorphisms of methylenetetrahydrofolate reductase and promoter methylation of MGMT and FHIT genes in diffuse large B cell lymphoma risk in Middle East.
|
Ann Hematol
|
2007
|
0.83
|
|
31
|
Role of nuclear factor-κB regulators TNFAIP3 and CARD11 in Middle Eastern diffuse large B-cell lymphoma.
|
Leuk Lymphoma
|
2012
|
0.82
|
|
32
|
A very low incidence of BRAF mutations in Middle Eastern colorectal carcinoma.
|
Mol Cancer
|
2014
|
0.81
|
|
33
|
Distinct gene expression profiles: nodal versus extranodal diffuse large B-cell lymphoma.
|
Oncology
|
2008
|
0.80
|
|
34
|
High epidermal growth factor receptor amplification rate but low mutation frequency in Middle East lung cancer population.
|
Hum Pathol
|
2006
|
0.77
|
|
35
|
Coexpression of activated c-Met and death receptor 5 predicts better survival in colorectal carcinoma.
|
Am J Pathol
|
2011
|
0.77
|
|
36
|
Epstein-Barr virus infection is not the sole cause of high prevalence for Hodgkin's lymphoma in Saudi Arabia.
|
Leuk Lymphoma
|
2006
|
0.76
|
|
37
|
Clinico-pathological significance of TNF alpha-induced protein3 (TNFAIP3) in Middle Eastern colorectal carcinoma.
|
Clin Epigenetics
|
2011
|
0.76
|
|
38
|
High throughput tissue microarray analysis of FHIT expression in diffuse large cell B-cell lymphoma from Saudi Arabia.
|
Mod Pathol
|
2006
|
0.75
|