Published in BMC Med Genet on May 22, 2006
Genetic mapping of a new heart rate QTL on chromosome 8 of spontaneously hypertensive rats. BMC Med Genet (2007) 0.79
A simple regression method for mapping quantitative trait loci in line crosses using flanking markers. Heredity (Edinb) (1992) 55.23
Precision mapping of quantitative trait loci. Genetics (1994) 32.57
Multiple trait analysis of genetic mapping for quantitative trait loci. Genetics (1995) 8.84
The genetic architecture of quantitative traits. Annu Rev Genet (2001) 7.69
Multitrait least squares for quantitative trait loci detection. Genetics (2000) 2.92
New target regions for human hypertension via comparative genomics. Genome Res (2000) 1.75
A biometrical genome search in rats reveals the multigenic basis of blood pressure variation. Genome Res (1995) 1.23
Multivariate linkage analysis of blood pressure and body mass index. Genet Epidemiol (2004) 0.94
De novo copy number variants identify new genes and loci in isolated sporadic tetralogy of Fallot. Nat Genet (2009) 3.86
Ten-year follow-up survival of the Medicine, Angioplasty, or Surgery Study (MASS II): a randomized controlled clinical trial of 3 therapeutic strategies for multivessel coronary artery disease. Circulation (2010) 2.64
Exercise training restores the endothelial progenitor cells number and function in hypertension: implications for angiogenesis. J Hypertens (2012) 1.63
N-domain angiotensin-converting enzyme isoform expression in tissues of Wistar and spontaneously hypertensive rats. J Hypertens (2005) 1.46
Metabolic syndrome and coronary artery disease: is there a gender specific effect? Int J Cardiol (2006) 1.42
Impact of number of vessels disease on outcome of patients with stable coronary artery disease: 5-year follow-up of the Medical, Angioplasty, and bypass Surgery study (MASS). Eur J Cardiothorac Surg (2008) 1.41
Meta-analysis of aspirin for the prevention of preeclampsia: do the main randomized controlled trials support an association between low-dose aspirin and a reduced risk of developing preeclampsia? Clinics (Sao Paulo) (2006) 1.39
NPHS2 R229Q functional variant is associated with microalbuminuria in the general population. Kidney Int (2004) 1.35
Regulatory variation in a TBX5 enhancer leads to isolated congenital heart disease. Hum Mol Genet (2012) 1.34
Human mesenchymal stem cells: from immunophenotyping by flow cytometry to clinical applications. Cytometry A (2012) 1.30
Meta-analysis of the association of 4 angiotensinogen polymorphisms with essential hypertension: a role beyond M235T? Hypertension (2008) 1.25
Molecular diagnostic and pathogenesis of hereditary hemochromatosis. Int J Mol Sci (2012) 1.22
Genetic background of patients from a university medical center in Manhattan: implications for personalized medicine. PLoS One (2011) 1.21
Neurofibromatosis-Noonan syndrome: molecular evidence of the concurrence of both disorders in a patient. Am J Med Genet A (2005) 1.19
Three endothelial nitric oxide (NOS3) gene polymorphisms in hypertensive and normotensive individuals: meta-analysis of 53 studies reveals evidence of publication bias. J Hypertens (2007) 1.14
APOE polymorphism is associated with lipid profile, but not with arterial stiffness in the general population. Lipids Health Dis (2010) 1.14
Beta2 adrenoceptor functional gene variants, obesity, and blood pressure level interactions in the general population. Hypertension (2003) 1.13
Assessment of the relationship between self-declared ethnicity, mitochondrial haplogroups and genomic ancestry in Brazilian individuals. PLoS One (2013) 1.11
TCF7L2 polymorphism rs7903146 is associated with coronary artery disease severity and mortality. PLoS One (2009) 1.11
Brazilian urban population genetic structure reveals a high degree of admixture. Eur J Hum Genet (2011) 1.10
Five-year follow-up of a randomized comparison between off-pump and on-pump stable multivessel coronary artery bypass grafting. The MASS III Trial. Circulation (2010) 1.10
Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development. Proc Natl Acad Sci U S A (2012) 1.08
Heritability of cardiovascular risk factors in a Brazilian population: Baependi Heart Study. BMC Med Genet (2008) 1.08
CYP2C19 and ABCB1 gene polymorphisms are differently distributed according to ethnicity in the Brazilian general population. BMC Med Genet (2011) 1.05
Circulating dipeptidyl peptidase IV activity correlates with cardiac dysfunction in human and experimental heart failure. Circ Heart Fail (2013) 1.04
Structural shifts of aldehyde dehydrogenase enzymes were instrumental for the early evolution of retinoid-dependent axial patterning in metazoans. Proc Natl Acad Sci U S A (2010) 1.04
Further evidence of the importance of RIT1 in Noonan syndrome. Am J Med Genet A (2014) 1.03
Impact of diabetes on five-year outcomes of patients with multivessel coronary artery disease. Ann Thorac Surg (2007) 1.02
Exercise training inhibits inflammatory cytokines and more than prevents myocardial dysfunction in rats with sustained beta-adrenergic hyperactivity. J Physiol (2010) 1.02
[Logistics of collection and transportation of biological samples and the organization of the central laboratory in the ELSA-Brasil]. Rev Saude Publica (2013) 1.02
Multicenter randomized trial of cell therapy in cardiopathies - MiHeart Study. Trials (2007) 1.01
Novel natural peptide substrates for endopeptidase 24.15, neurolysin, and angiotensin-converting enzyme. J Biol Chem (2002) 1.01
Gene variation in resistant hypertension: multilocus analysis of the angiotensin 1-converting enzyme, angiotensinogen, and endothelial nitric oxide synthase genes. DNA Cell Biol (2011) 1.01
Effect of the G-308A polymorphism of the tumor necrosis factor alpha gene on the risk of ischemic heart disease and ischemic stroke: a meta-analysis. Am Heart J (2007) 1.01
Mutations in the human phospholamban gene in patients with heart failure. Am Heart J (2011) 0.99
SLCO1B1 rs4149056 polymorphism associated with statin-induced myopathy is differently distributed according to ethnicity in the Brazilian general population: Amerindians as a high risk ethnic group. BMC Med Genet (2011) 0.98
Association between platelet P2Y12 haplotype and risk of cardiovascular events in chronic coronary disease. Thromb Res (2006) 0.97
Angiotensinogen 235T allele "dosage" is associated with blood pressure phenotypes. Hypertension (2003) 0.95
Effectiveness of coadministration of varenicline, bupropion, and serotonin reuptake inhibitors in a smoking cessation program in the real-life setting. Nicotine Tob Res (2012) 0.94
Effects of depression, anxiety, comorbidity, and antidepressants on resting-state heart rate and its variability: an ELSA-Brasil cohort baseline study. Am J Psychiatry (2014) 0.93
Angiotensinogen M235T polymorphism is associated with coronary artery disease severity. Clin Chim Acta (2005) 0.92
Lower heart rate variability is associated with higher serum high-sensitivity C-reactive protein concentration in healthy individuals aged 46 years or more. Int J Cardiol (2006) 0.92
ALDH1A2 (RALDH2) genetic variation in human congenital heart disease. BMC Med Genet (2009) 0.92
Methylenetetrahydrofolate reductase (MTHFR) c677t gene variant modulates the homocysteine folate correlation in a mild folate-deficient population. Clin Chim Acta (2004) 0.92
Two new mutations in the HIF2A gene associated with erythrocytosis. Am J Hematol (2012) 0.92
Multilocus analyses of seven candidate genes suggest interacting pathways for obesity-related traits in Brazilian populations. Obesity (Silver Spring) (2011) 0.91
Metabolic syndrome determinants in an urban population from Brazil: social class and gender-specific interaction. Int J Cardiol (2007) 0.90
Thioredoxin interacting protein genetic variation is associated with diabetes and hypertension in the Brazilian general population. Atherosclerosis (2011) 0.90
High-sensitivity C-reactive protein concentration in a healthy Brazilian population. Int J Cardiol (2004) 0.89
Association of mannose-binding lectin gene polymorphism but not of mannose-binding serine protease 2 with chronic severe aortic regurgitation of rheumatic etiology. Clin Vaccine Immunol (2008) 0.89
Additional value of dipyridamole stress myocardial perfusion by 64-row computed tomography in patients with coronary stents. J Cardiovasc Comput Tomogr (2011) 0.89
Association of genetic variants in the adiponectin encoding gene (ADIPOQ) with type 2 diabetes in Japanese Brazilians. J Diabetes Complications (2009) 0.89
The effect of Sao Paulo's smoke-free legislation on carbon monoxide concentration in hospitality venues and their workers. Tob Control (2010) 0.88
Nuclear Factor (NF) kappaB polymorphism is associated with heart function in patients with heart failure. BMC Med Genet (2010) 0.88
Determinants of left ventricular mass and presence of metabolic risk factors in normotensive individuals. Int J Cardiol (2008) 0.88
Heritability of physical activity traits in Brazilian families: the Baependi Heart Study. BMC Med Genet (2011) 0.87
Retinoic acid and VEGF delay smooth muscle relative to endothelial differentiation to coordinate inner and outer coronary vessel wall morphogenesis. Circ Res (2010) 0.87
Obesity-associated activation of angiotensin and endothelin in the cardiovascular system. Int J Biochem Cell Biol (2003) 0.87
Association between genetics of diabetes, coronary artery disease, and macrovascular complications: exploring a common ground hypothesis. Rev Diabet Stud (2011) 0.87
Holt-Oram syndrome: novel TBX5 mutation and associated anomalous right coronary artery. Cardiol Young (2011) 0.86
Impact of metabolic syndrome on the outcome of patients with stable coronary artery disease: 2-year follow-up of the MASS II study. Coron Artery Dis (2008) 0.86
AT1 receptor blocker potentiates shear-stress induced nitric oxide production via modulation of eNOS phosphorylation of residues Thr(495) and Ser(1177.). Biochem Biophys Res Commun (2013) 0.86
Local renin-angiotensin system regulates left ventricular hypertrophy induced by swimming training independent of circulating renin: a pharmacological study. J Renin Angiotensin Aldosterone Syst (2009) 0.86
Chronic beta-adrenoceptor stimulation and cardiac hypertrophy with no induction of circulating renin. Eur J Pharmacol (2005) 0.86
Hereditary hemochromatosis: mutations in genes involved in iron homeostasis in Brazilian patients. Blood Cells Mol Dis (2011) 0.85
NPHS2 mutations in adult patients with primary focal segmental glomerulosclerosis. J Nephrol (2006) 0.85
Clinical variability in a Noonan syndrome family with a new PTPN11 gene mutation. Am J Med Genet A (2004) 0.85
Echocardiographic reference values in a sample of asymptomatic adult Brazilian population. Arq Bras Cardiol (2007) 0.85
Glu298Asp eNOS gene polymorphism causes attenuation in nonexercising muscle vasodilatation. Physiol Genomics (2009) 0.85
The influence of tumor necrosis factor -308 and C-reactive protein G1059C gene variants on serum concentration of C-reactive protein: evidence for an age-dependent association. Clin Chim Acta (2004) 0.84
Association of alpha1a-adrenergic receptor polymorphism and blood pressure phenotypes in the Brazilian population. BMC Cardiovasc Disord (2008) 0.84
MYLIP p.N342S polymorphism is not associated with lipid profile in the Brazilian population. Lipids Health Dis (2012) 0.84
Genetic analyses of smoking initiation, persistence, quantity, and age-at-onset of regular cigarette use in Brazilian families: the Baependi Heart Study. BMC Med Genet (2012) 0.84
Association between ADAMTS13 polymorphisms and risk of cardiovascular events in chronic coronary disease. Thromb Res (2009) 0.84