Published in Curr Med Chem on January 01, 2006
Activation of phosphatidylcholine cycle enzymes in human epithelial ovarian cancer cells. Cancer Res (2010) 1.65
Choline and betaine in health and disease. J Inherit Metab Dis (2010) 1.61
Radiation treatment monitoring using multimodal functional imaging: PET/CT ((18)F-Fluoromisonidazole & (18)F-Fluorocholine) and DCE-US. J Transl Med (2015) 1.39
Phosphatidylcholine and the CDP-choline cycle. Biochim Biophys Acta (2012) 1.28
Molecular imaging of prostate cancer: PET radiotracers. AJR Am J Roentgenol (2012) 1.22
Detection of aggressive primary prostate cancer with 11C-choline PET/CT using multimodality fusion techniques. J Nucl Med (2009) 1.16
PSMA-targeted theranostic nanoplex for prostate cancer therapy. ACS Nano (2012) 1.15
Comparative performance of PET tracers in biochemical recurrence of prostate cancer: a critical analysis of literature. Am J Nucl Med Mol Imaging (2014) 1.13
Choline kinase alpha and hexokinase-2 protein expression in hepatocellular carcinoma: association with survival. PLoS One (2012) 1.12
Lipid metabolism, apoptosis and cancer therapy. Int J Mol Sci (2015) 1.11
Inhibition of phosphatidylcholine-specific phospholipase C results in loss of mesenchymal traits in metastatic breast cancer cells. Breast Cancer Res (2012) 1.04
Functional regulation of phospholipase D expression in cancer and inflammation. J Biol Chem (2014) 0.86
The calcium-sensing receptor in the breast. Best Pract Res Clin Endocrinol Metab (2013) 0.85
Choline promotes nicotinic receptor alpha4 + beta2 up-regulation. J Biol Chem (2010) 0.84
Characterization of choline uptake in prostate cancer cells following bicalutamide and docetaxel treatment. Eur J Nucl Med Mol Imaging (2009) 0.80
Characterization of human bladder cell membrane during cancer transformation. J Membr Biol (2015) 0.80
Cholinergic Targets in Lung Cancer. Curr Pharm Des (2016) 0.79
Influence of multidrug resistance on (18)F-FCH cellular uptake in a glioblastoma model. Eur J Nucl Med Mol Imaging (2009) 0.79
Reciprocal regulation of the cholinic phenotype and epithelial-mesenchymal transition in glioblastoma cells. Oncotarget (2016) 0.77
Identification and classification of small molecule kinases: insights into substrate recognition and specificity. BMC Evol Biol (2016) 0.77
Choline Metabolism Alteration: A Focus on Ovarian Cancer. Front Oncol (2016) 0.76
Metabolomics of Head and Neck Cancer: A Mini-Review. Front Physiol (2016) 0.75
Positron emission tomography in imaging evaluation of staging, restaging, treatment response, and prognosis in prostate cancer. Abdom Radiol (2016) 0.75
(18)F Fluorocholine Dynamic Time-of-Flight PET/MR Imaging in Patients with Newly Diagnosed Intermediate- to High-Risk Prostate Cancer: Initial Clinical-Pathologic Comparisons. Radiology (2016) 0.75
CHKA mediates the poor prognosis of lung adenocarcinoma and acts as a prognostic indicator. Oncol Lett (2016) 0.75
Simultaneous Quantification of Serum Multi-Phospholipids as Potential Biomarkers for Differentiating Different Pathophysiological states of lung, stomach, intestine, and pancreas. J Cancer (2017) 0.75
Vitamin D status and bone mineral density in women of reproductive and postmenopausal age groups: a cross-sectional study from south India. J Assoc Physicians India (2011) 1.64
Cation-π interaction: its role and relevance in chemistry, biology, and material science. Chem Rev (2012) 1.49
Virtual screening in drug discovery -- a computational perspective. Curr Protein Pept Sci (2007) 1.32
The significance of the alkene size and the nature of the metal ion in metal-alkene complexes: a theoretical study. Dalton Trans (2012) 1.02
Homology modeling of membrane proteins: a critical assessment. Comput Biol Chem (2006) 1.01
Exploring the size dependence of cyclic and acyclic pi-systems on cation-pi binding. Phys Chem Chem Phys (2007) 0.98
Comprehensive study on the solvation of mono- and divalent metal cations: Li+, Na+, K+, Be2+, Mg2+ and Ca2+. J Phys Chem A (2008) 0.98
Synthesis, structure analysis, and antibacterial activity of some novel 10-substituted 2-(4-piperidyl/phenyl)-5,5-dioxo[1,2,4]triazolo[1,5-b][1,2,4]benzothiadiazine derivatives. Bioorg Med Chem Lett (2007) 0.97
Where to bind in buckybowls? The dilemma of a metal ion. Phys Chem Chem Phys (2012) 0.97
On the cooperativity of cation-pi and hydrogen bonding interactions. J Phys Chem B (2008) 0.96
Cation [M = H+, Li+, Na+, K+, Ca2+, Mg2+, NH4+, and NMe4+] interactions with the aromatic motifs of naturally occurring amino acids: a theoretical study. J Phys Chem A (2005) 0.94
What factors influence the rate constant of substrate epoxidation by compound I of cytochrome P450 and analogous iron(IV)-oxo oxidants? J Am Chem Soc (2010) 0.94
Aromatic-Aromatic Interactions Database, A(2)ID: an analysis of aromatic π-networks in proteins. Int J Biol Macromol (2011) 0.92
Mechanism of S-oxygenation by a cysteine dioxygenase model complex. J Phys Chem A (2011) 0.90
Comparison of computational methods to model DNA minor groove binders. J Chem Inf Model (2011) 0.89
Subtype selectivity in phosphodiesterase 4 (PDE4): a bottleneck in rational drug design. Curr Pharm Des (2008) 0.87
Viability of clathrate hydrates as CO2 capturing agents: a theoretical study. J Phys Chem A (2011) 0.85
Methyl cation affinities of commonly used organocatalysts. J Am Chem Soc (2008) 0.85
Protein ligand interaction database (PLID). Comput Biol Chem (2008) 0.85
Effect of the axial ligand on substrate sulfoxidation mediated by iron(IV)-oxo porphyrin cation radical oxidants. Chemistry (2011) 0.85
Cation-pi interactions of bare and coordinatively saturated metal ions: contrasting structural and energetic characteristics. J Phys Chem B (2007) 0.85
Molecular dynamics investigation on a series of HIV protease inhibitors: assessing the performance of MM-PBSA and MM-GBSA approaches. J Chem Inf Model (2012) 0.84
Explicit solvent effect on cation-pi interactions: a first principle investigation. J Phys Chem B (2009) 0.83
Potential choline kinase inhibitors: a molecular modeling study of bis-quinolinium compounds. J Mol Graph Model (2008) 0.83
Molecular modeling studies of pyridopurinone derivatives--potential phosphodiesterase 5 inhibitors. J Mol Graph Model (2007) 0.83
Axial ligand effect on the rate constant of aromatic hydroxylation by iron(IV)-oxo complexes mimicking cytochrome P450 enzymes. J Phys Chem B (2011) 0.82
Sequence, structure, and active site analyses of p38 MAP kinase: exploiting DFG-out conformation as a strategy to design new type II leads. J Chem Inf Model (2010) 0.82
Remarkable enhancement in the DNA-binding ability of C2-fluoro substituted pyrrolo[2,1-c][1,4]benzodiazepines and their anticancer potential. Bioorg Med Chem (2009) 0.82
Formation of linear polymers with pendant vinyl groups via inclusion complex mediated polymerization of divinyl monomers. J Am Chem Soc (2006) 0.82
Cation-aromatic database. Proteins (2007) 0.82
Novel targets for antiinflammatory and antiarthritic agents. Curr Pharm Des (2006) 0.81
Aromatase inhibitors: a new paradigm in breast cancer treatment. Curr Med Chem Anticancer Agents (2004) 0.80
Generation of regiospecific carbanions under electrospray ionisation conditions and their selectivity in ion-molecule reactions with CO2. Rapid Commun Mass Spectrom (2006) 0.80
Virtual screening filters for the design of type II p38 MAP kinase inhibitors: a fragment based library generation approach. J Mol Graph Model (2012) 0.80
Hydrogen bonding in water clusters and their ionized counterparts. J Phys Chem B (2010) 0.79
Oxidative properties of a nonheme Ni(II)(O2) complex: Reactivity patterns for C-H activation, aromatic hydroxylation and heteroatom oxidation. Chem Commun (Camb) (2011) 0.79
Synthesis and theoretical studies on energetics of novel N- and O- perfluoroalkyl triazole tagged thienopyrimidines--their potential as adenosine receptor ligands. Eur J Med Chem (2010) 0.79
Density functional theory study on the effect of substitution and ring annelation to the rim of corannulene. J Org Chem (2004) 0.79
Ab initio investigation of benzene clusters: molecular tailoring approach. J Chem Phys (2010) 0.79
FDA approved drugs complexed to their targets: evaluating pose prediction accuracy of docking protocols. J Mol Model (2012) 0.79
Recent advances in molecular modeling and medicinal chemistry aspects of phospho-glycoprotein. Curr Drug Metab (2006) 0.79
Estimating the stereoinductive potential of cinchona alkaloids with a prochiral probe approach. Org Lett (2008) 0.79
Cyclotriphosphazene ring as a platform for multiporphyrin assemblies. Chemistry (2009) 0.78
Steric factors override thermodynamic driving force in regioselectivity of proline hydroxylation by prolyl-4-hydroxylase enzymes. J Phys Chem A (2010) 0.78
Competitive Diels-Alder reactions: cyclopentadiene and phospholes with butadiene. J Phys Chem A (2005) 0.78
From subtle to substantial: role of metal ions on pi-pi interactions. J Phys Chem B (2006) 0.78
Modeling anti-HIV compounds: the role of analogue-based approaches. Curr Comput Aided Drug Des (2012) 0.78
Impact of the chirality and curvature of carbon nanostructures on their interaction with aromatics and amino acids. Chemphyschem (2013) 0.78
Design of 1-arylsulfamido-2-alkylpiperazine derivatives as secreted PLA2 inhibitors. J Mol Model (2010) 0.78
Rational approaches towards lead optimization of kinase inhibitors: the issue of specificity. Curr Pharm Des (2013) 0.78
Stereoelectronic effect of curved aromatic structures: favoring the unexpected endo conformation of benzylic-substituted sumanene. Angew Chem Int Ed Engl (2013) 0.78
A theoretical study on interaction of cyclopentadienyl ligand with alkali and alkaline earth metals. J Phys Chem B (2010) 0.78
Virtual high throughput screening in new lead identification. Comb Chem High Throughput Screen (2011) 0.77
Design, synthesis and cytotoxic studies on the simplified oxy analog of eleutherobin. Bioorg Med Chem Lett (2004) 0.77
Characterization of calcium and magnesium binding domains of human 5-lipoxygenase. Biochem Biophys Res Commun (2004) 0.77
Efficient estimation of MMGBSA-based BEs for DNA and aromatic furan amidino derivatives. J Biomol Struct Dyn (2012) 0.77
Synthesis, DNA-binding ability and anticancer activity of benzothiazole/benzoxazole-pyrrolo[2,1-c][1,4]benzodiazepine conjugates. Bioorg Med Chem (2010) 0.77
Conjugate acene fused buckybowls: evaluating their suitability for p-type, ambipolar and n-type air stable organic semiconductors. Phys Chem Chem Phys (2013) 0.77
Propargyl/methyl furanosides as potential glycosyl donors. Chem Commun (Camb) (2011) 0.76
Metabolite profiling and biological activities of bioactive compounds produced by Chrysosporium lobatum strain BK-3 isolated from Kaziranga National Park, Assam, India. Springerplus (2013) 0.76
The efficacy of conceptual DFT descriptors and docking scores on the QSAR models of HIV protease inhibitors. Med Chem (2012) 0.76
DSTHO: database of siRNAs targeted at human oncogenes: a statistical analysis. Int J Biol Macromol (2006) 0.76
Analysis of HIV protease binding pockets based on 3D shape and electrostatic potential descriptors. Chem Biol Drug Des (2011) 0.76
Structural and active site analysis of plasmepsins of Plasmodium falciparum: potential anti-malarial targets. Int J Biol Macromol (2005) 0.76
Proton binding sites and conformational analysis of H+K(+)-ATPase. Biochem Biophys Res Commun (2005) 0.76
The nucleotide, inhibitor, and cation binding sites of P-type II ATPases. Chem Biol Drug Des (2012) 0.76
Strategies to design pyrazolyl urea derivatives for p38 kinase inhibition: a molecular modeling study. J Comput Aided Mol Des (2007) 0.75
Structure-energy relationships in curved polycyclic aromatic hydrocarbons: study of benzocorannulenes. J Org Chem (2002) 0.75
Estimating the binding ability of onium ions with CO₂ and π systems: a computational investigation. Phys Chem Chem Phys (2014) 0.75
A computational study on pi and sigma modes of metal ion binding to heteroaromatics (CH)(5-m)X(m) and (CH)(6-m)X(m) (X = N and P): contrasting preferences between nitrogen- and phosphorous-substituted rings. J Phys Chem A (2006) 0.75
Gold(I)-catalyzed unprecedented rearrangement reaction between 2-aminobenzaldehydes with propargyl amines: an expedient route to 3-aminoquinolines. Chemistry (2012) 0.75
Cation-alkane interaction. J Phys Chem A (2014) 0.75
Silaaromaticity in polycyclic systems: a computational study. J Org Chem (2003) 0.75
Differentiation of diastereomeric conduramine derivatives under electron ionization and chemical ionization mass spectral conditions. Rapid Commun Mass Spectrom (2007) 0.75
A theoretical study on structural, spectroscopic and energetic properties of acetamide clusters [CH3CONH2] (n=1-15). Phys Chem Chem Phys (2011) 0.75
30pi aromatic meso-substituted heptaphyrin isomers: syntheses, characterization, and spectroscopic studies. J Org Chem (2002) 0.75
Differentiation of diastereomeric N-aryltetrahydropyrano/tetrahydrofuranochromenylamines under electron ionization and chemical ionization conditions. Rapid Commun Mass Spectrom (2007) 0.75
Active site acidic residues and structural analysis of modelled human aromatase: a potential drug target for breast cancer. J Comput Aided Mol Des (2006) 0.75
Effect of solvation on ion binding to imidazole and methylimidazole. J Phys Chem A (2011) 0.75
Structural and conformational changes concomitant with the E1-E2 transition in H(+)K(+)-ATPase: a comparative protein modeling study. Biochem Biophys Res Commun (2004) 0.75
The effect of spacer chain length on ion binding to bidentate alpha,omega-diamines: contrasting ordering for H+ and Li+ ion affinities. Chem Commun (Camb) (2005) 0.75
A lipophilic hexaporphyrin assembly supported on a stannoxane core. J Am Chem Soc (2005) 0.75
Theoretical studies on inclusion complexes of cyclodextrins. J Phys Chem A (2009) 0.75
Structural and energetic preferences of pi, sigma, and bidentate cation binding (Li(+), Na(+), and Mg(2+)) to aromatic amines (Ph-(CH(2))(n)-NH(2), n = 2-5): a theoretical study. J Phys Chem A (2009) 0.75
Evaluating the efficacy of amino acids as CO2 capturing agents: a first principles investigation. Environ Sci Technol (2011) 0.75
A comprehensive conformational analysis of tryptophan, its ionic and dimeric forms. J Comput Chem (2013) 0.75
Further shortening of the C-C single bond in substituted tetrahedranyl tetrahedrane systems: an energy decomposition analysis. J Phys Chem A (2008) 0.75
Estimating regio and stereoselectivity in [4+2] cycloadditions of vinyl-substituted cyclic dienes with maleic anhydride. J Phys Chem A (2009) 0.75