NF-kappaB as a potential therapeutic target in osteoarthritis and rheumatoid arthritis.

PubWeight™: 2.07‹?› | Rank: Top 2%

🔗 View Article (PMID 16730463)

Published in Osteoarthritis Cartilage on May 26, 2006

Authors

J A Roman-Blas1, S A Jimenez

Author Affiliations

1: Division of Rheumatology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA19107-5541, USA. jorge.roman-blas@jefferson.edu

Articles citing this

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis. Nat Rev Rheumatol (2010) 5.14

Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. BMC Med Genomics (2009) 2.36

NF-kappaB signaling: multiple angles to target OA. Curr Drug Targets (2010) 1.89

The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of osteoarthritis. Mediators Inflamm (2014) 1.76

TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β-induced rat osteoarthritis chondrocytes in vitro. Arthritis Res Ther (2012) 1.30

Immunopathogenesis of osteoarthritis. Clin Immunol (2013) 1.29

IGF-1 and PDGF-bb suppress IL-1β-induced cartilage degradation through down-regulation of NF-κB signaling: involvement of Src/PI-3K/AKT pathway. PLoS One (2011) 1.27

The role of changes in extracellular matrix of cartilage in the presence of inflammation on the pathology of osteoarthritis. Biomed Res Int (2013) 1.18

Modulation of TGF-beta signaling by proinflammatory cytokines in articular chondrocytes. Osteoarthritis Cartilage (2007) 1.16

The epigenetic effect of glucosamine and a nuclear factor-kappa B (NF-kB) inhibitor on primary human chondrocytes--implications for osteoarthritis. Biochem Biophys Res Commun (2011) 1.15

Epigenetic modifications in rheumatoid arthritis. Arthritis Res Ther (2008) 1.13

Immunomodulatory and anti-inflammatory effects of chondroitin sulphate. J Cell Mol Med (2009) 1.02

Allelic variants of IL1R1 gene associate with severe hand osteoarthritis. BMC Med Genet (2010) 1.01

Inhibition of the IKK/NF-κB pathway by AAV gene transfer improves muscle regeneration in older mdx mice. Gene Ther (2010) 1.00

Delphinidin inhibits IL-1β-induced activation of NF-κB by modulating the phosphorylation of IRAK-1(Ser376) in human articular chondrocytes. Rheumatology (Oxford) (2013) 0.97

Activation of nuclear factor-κB in the brain after experimental subarachnoid hemorrhage and its potential role in delayed brain injury. PLoS One (2013) 0.96

Role of NFkappaB in an animal model of complex regional pain syndrome-type I (CRPS-I). J Pain (2009) 0.94

Polydnaviral ankyrin proteins aid parasitic wasp survival by coordinate and selective inhibition of hematopoietic and immune NF-kappa B signaling in insect hosts. PLoS Pathog (2013) 0.94

Differential requirements for IKKalpha and IKKbeta in the differentiation of primary human osteoarthritic chondrocytes. Arthritis Rheum (2008) 0.92

Multi-omic landscape of rheumatoid arthritis: re-evaluation of drug adverse effects. Front Cell Dev Biol (2014) 0.92

In vivo luminescence imaging of NF-κB activity and serum cytokine levels predict pain sensitivities in a rodent model of osteoarthritis. Arthritis Rheumatol (2014) 0.90

Nutraceuticals: potential for chondroprotection and molecular targeting of osteoarthritis. Int J Mol Sci (2013) 0.88

Targeting TNF-α and NF-κB activation by bee venom: role in suppressing adjuvant induced arthritis and methotrexate hepatotoxicity in rats. PLoS One (2013) 0.88

Fluid shear stress-induced osteoarthritis: roles of cyclooxygenase-2 and its metabolic products in inducing the expression of proinflammatory cytokines and matrix metalloproteinases. FASEB J (2013) 0.86

Characterization of NF-kB-mediated inhibition of catechol-O-methyltransferase. Mol Pain (2009) 0.85

Caesalpinia sappan extract inhibits IL1β-mediated overexpression of matrix metalloproteinases in human chondrocytes. Genes Nutr (2011) 0.84

Anti-arthritic effects of crocin in interleukin-1β-treated articular chondrocytes and cartilage in a rabbit osteoarthritic model. Inflamm Res (2012) 0.84

Natural killer cells and their role in rheumatoid arthritis: friend or foe? ScientificWorldJournal (2012) 0.84

Emerging roles of SUMO modification in arthritis. Gene (2010) 0.84

Oleanane-triterpenoids from Panax stipuleanatus inhibit NF-κB. J Ginseng Res (2013) 0.84

Coptisine Prevented IL-β-Induced Expression of Inflammatory Mediators in Chondrocytes. Inflammation (2016) 0.84

Pathophysiology of osteoarthritis: canonical NF-κB/IKKβ-dependent and kinase-independent effects of IKKα in cartilage degradation and chondrocyte differentiation. RMD Open (2015) 0.83

DIO2 modifies inflammatory responses in chondrocytes. Osteoarthritis Cartilage (2012) 0.83

Dysregulated miR-34a-SIRT1-acetyl p65 axis is a potential mediator of immune activation in the colon during chronic simian immunodeficiency virus infection of rhesus macaques. J Immunol (2014) 0.83

Dynamic compression alters NFkappaB activation and IkappaB-alpha expression in IL-1beta-stimulated chondrocyte/agarose constructs. Inflamm Res (2009) 0.82

Sulforaphane has opposing effects on TNF-alpha stimulated and unstimulated synoviocytes. Arthritis Res Ther (2012) 0.82

A systems biology approach to suppress TNF-induced proinflammatory gene expressions. Cell Commun Signal (2013) 0.82

Expression and pathological effects of periostin in human osteoarthritis cartilage. BMC Musculoskelet Disord (2015) 0.81

Collagen metabolism of human osteoarthritic articular cartilage as modulated by bovine collagen hydrolysates. PLoS One (2013) 0.81

Connexin43 enhances the expression of osteoarthritis-associated genes in synovial fibroblasts in culture. BMC Musculoskelet Disord (2014) 0.81

A failure of TNFAIP3 negative regulation maintains sustained NF-κB activation in Sjögren's syndrome. Histochem Cell Biol (2011) 0.81

Conditioned media from adipose-tissue-derived mesenchymal stem cells downregulate degradative mediators induced by interleukin-1β in osteoarthritic chondrocytes. Mediators Inflamm (2013) 0.80

RNA therapeutics targeting osteoclast-mediated excessive bone resorption. Adv Drug Deliv Rev (2011) 0.80

Role of Thyroid Hormones in Skeletal Development and Bone Maintenance. Endocr Rev (2016) 0.79

Neuropilin-1 is upregulated in Sjögren's syndrome and contributes to pathological neovascularization. Histochem Cell Biol (2012) 0.79

Mesenchymal stem cells alleviate experimental rheumatoid arthritis through microRNA-regulated IκB expression. Sci Rep (2016) 0.79

Anti-inflammatory strategies in cartilage repair. Tissue Eng Part B Rev (2014) 0.78

SDF‑1/CXCR4 axis induces apoptosis of human degenerative nucleus pulposus cells via the NF‑κB pathway. Mol Med Rep (2016) 0.78

Soft tissue injections in the athlete. Sports Health (2009) 0.78

Investigation of the cytokine response to NF-κB decoy oligonucleotide coated polysaccharide based nanoparticles in rheumatoid arthritis in vitro models. Arthritis Res Ther (2015) 0.78

Expression of pro-inflammatory mediators is inhibited by an avocado/soybean unsaponifiables and epigallocatechin gallate combination. J Inflamm (Lond) (2014) 0.78

Protective effects of biochanin A on articular cartilage: in vitro and in vivo studies. BMC Complement Altern Med (2014) 0.78

SeMet mediates anti-inflammation in LPS-induced U937 cells targeting NF-κB signaling pathway. Inflammation (2015) 0.77

Damage-Associated Molecular Patterns Generated in Osteoarthritis Directly Excite Murine Nociceptive Neurons Through Toll-like Receptor 4. Arthritis Rheumatol (2015) 0.77

Functional characterization of a competitive peptide antagonist of p65 in human macrophage-like cells suggests therapeutic potential for chronic inflammation. Drug Des Devel Ther (2014) 0.76

Review: Long Noncoding RNAs in the Regulation of Inflammatory Pathways in Rheumatoid Arthritis and Osteoarthritis. Arthritis Rheumatol (2016) 0.76

MicroRNA-21 Promotes Proliferation of Fibroblast-Like Synoviocytes through Mediation of NF-κB Nuclear Translocation in a Rat Model of Collagen-Induced Rheumatoid Arthritis. Biomed Res Int (2016) 0.76

Systemic administration of strontium or NBD peptide ameliorates early stage cartilage degradation of mouse mandibular condyles. Osteoarthritis Cartilage (2015) 0.76

Effects of mesenchymal stem cells on interleukin-1β-treated chondrocytes and cartilage in a rat osteoarthritic model. Mol Med Rep (2015) 0.76

Interleukin-1β induces fibroblast growth factor 2 expression and subsequently promotes endothelial progenitor cell angiogenesis in chondrocytes. Clin Sci (Lond) (2016) 0.76

Adult mice lacking the type 2 iodothyronine deiodinase have increased subchondral bone but normal articular cartilage. Thyroid (2015) 0.76

Suppression of NF-κB activity via nanoparticle-based siRNA delivery alters early cartilage responses to injury. Proc Natl Acad Sci U S A (2016) 0.76

Plumbagin Prevents IL-1β-Induced Inflammatory Response in Human Osteoarthritis Chondrocytes and Prevents the Progression of Osteoarthritis in Mice. Inflammation (2017) 0.76

Lactoferrin from Camelus dromedarius Inhibits Nuclear Transcription Factor-kappa B Activation, Cyclooxygenase-2 Expression and Prostaglandin E2 Production in Stimulated Human Chondrocytes. Pharmacognosy Res (2016) 0.75

The involvement and possible mechanism of NR4A1 in chondrocyte apoptosis during osteoarthritis. Am J Transl Res (2017) 0.75

Electrospun Microfiber Scaffolds with Anti-Inflammatory Tributanoylated N-Acetyl-d-Glucosamine Promote Cartilage Regeneration. Tissue Eng Part A (2016) 0.75

Tenuigenin Prevents IL-1β-induced Inflammation in Human Osteoarthritis Chondrocytes by Suppressing PI3K/AKT/NF-κB Signaling Pathway. Inflammation (2016) 0.75

The effects of a moderate exercise program on knee osteoarthritis in male wistar rats. Iran J Basic Med Sci (2013) 0.75

A novel rat model of heart failure induced by high methionine diet showing evidence of association between hyperhomocysteinemia and activation of NF-kappaB. Am J Transl Res (2016) 0.75

Anti-Inflammatory Effects of TRAF-Interacting Protein in Rheumatoid Arthritis Fibroblast-Like Synoviocytes. Mediators Inflamm (2016) 0.75

IL-1β impedes the chondrogenic differentiation of synovial fluid mesenchymal stem cells in the human temporomandibular joint. Int J Mol Med (2016) 0.75

A Tale of Two Joints: The Role of Matrix Metalloproteases in Cartilage Biology. Dis Markers (2016) 0.75

Inhibition of transforming growth factor β-activated kinase 1 prevents inflammation-related cartilage degradation in osteoarthritis. Sci Rep (2016) 0.75

Design, synthesis and biological evaluation of bivalent benzoxazolone and benzothiazolone ligands as potential anti-inflammatory/analgesic agents. Bioorg Med Chem (2015) 0.75

Anti-angiogenic effect of total saponins of Rhizoma Dioscorea nipponica on collagen induced-arthritis in rats. Exp Ther Med (2016) 0.75

Glycemia-dependent nuclear factor κB activation contributes to mechanical allodynia in rats with chronic postischemia pain. Anesthesiology (2013) 0.75

New developments in the treatment of osteoarthritis - focus on biologic agents. Open Access Rheumatol (2015) 0.75

Analgesic and anti-Inflammatory effect of UP3005, a botanical composition Containing two standardized extracts of Uncaria gambir and Morus alba. Pharmacognosy Res (2015) 0.75

Topically applied phospho-sulindac hydrogel is efficacious and safe in the treatment of experimental arthritis in rats. Pharm Res (2013) 0.75

Effects of platelet-rich plasma in a model of bovine endometrial inflammation in vitro. Reprod Biol Endocrinol (2016) 0.75

A Polyphenol-rich Pomegranate Fruit Extract Suppresses NF-κB and IL-6 Expression by Blocking the Activation of IKKβ and NIK in Primary Human Chondrocytes. Phytother Res (2017) 0.75

Chrysin Attenuates IL-1β-Induced Expression of Inflammatory Mediators by Suppressing NF-κB in Human Osteoarthritis Chondrocytes. Inflammation (2017) 0.75

Role of glucocorticoid-induced leucine zipper (GILZ) in inflammatory bone loss. PLoS One (2017) 0.75

Identification of key genes associated with rheumatoid arthritis with bioinformatics approach. Medicine (Baltimore) (2017) 0.75

Phytochemicals as potential antidotes for targeting NF-κB in rheumatoid arthritis. 3 Biotech (2017) 0.75

Sanguinarine protects against osteoarthritis by suppressing the expression of catabolic proteases. Oncotarget (2017) 0.75

The Impact of Synovial NF-κB Activation on Apoptosis Pattern Change During Adjuvant-induced Inflammation. Basic Clin Neurosci (2017) 0.75

Generating testable hypotheses for schizophrenia and rheumatoid arthritis pathogenesis by integrating epidemiological, genomic, and protein interaction data. NPJ Schizophr (2017) 0.75

Sivelestat sodium hydrate improves post-traumatic knee osteoarthritis through nuclear factor-κB in a rat model. Exp Ther Med (2017) 0.75

Mangiferin Inhibits IL-1β-Induced Inflammatory Response by Activating PPAR-γ in Human Osteoarthritis Chondrocytes. Inflammation (2016) 0.75

Articles by these authors

(truncated to the top 100)

Osteoarthritis cartilage histopathology: grading and staging. Osteoarthritis Cartilage (2005) 6.77

Identification of fetal DNA and cells in skin lesions from women with systemic sclerosis. N Engl J Med (1998) 4.08

A disease severity scale for systemic sclerosis: development and testing. J Rheumatol (1999) 2.85

Treatment of systemic sclerosis with extracorporeal photochemotherapy. Results of a multicenter trial. Arch Dermatol (1992) 2.33

Stop codon in the procollagen II gene (COL2A1) in a family with the Stickler syndrome (arthro-ophthalmopathy). Proc Natl Acad Sci U S A (1991) 2.24

Transforming growth factor beta (TGF beta) causes a persistent increase in steady-state amounts of type I and type III collagen and fibronectin mRNAs in normal human dermal fibroblasts. Biochem J (1987) 2.23

Genetic linkage of a polymorphism in the type II procollagen gene (COL2A1) to primary osteoarthritis associated with mild chondrodysplasia. N Engl J Med (1990) 1.93

A transport form of collagen from embryonic tendon: electron microscopic demonstration of an NH 2 -terminal extension and evidence suggesting the presence of cystine in the molecule (chick embryo-tropocollagen-gel filtration). Proc Natl Acad Sci U S A (1972) 1.79

Selective inhibition of human diploid fibroblast collagen synthesis by interferons. J Clin Invest (1984) 1.70

Endoluminal ultrasonography of the distal esophagus in systemic sclerosis. Gastroenterology (1993) 1.60

A tandem duplication within the fibrillin 1 gene is associated with the mouse tight skin mutation. Genome Res (1996) 1.57

Inhibition of collagen synthesis by mononuclear cell supernates. J Exp Med (1979) 1.55

Stimulation of normal human fibroblast collagen production and processing by transforming growth factor-beta. Biochem Biophys Res Commun (1986) 1.51

The cause and pathogenesis of the eosinophilia-myalgia syndrome. Ann Intern Med (1992) 1.46

Effect of joint motion on experimental calcium pyrophosphate dihydrate crystal induced arthritis. J Rheumatol (1990) 1.46

Genetic linkage analysis of hereditary arthro-ophthalmopathy (Stickler syndrome) and the type II procollagen gene. Am J Hum Genet (1989) 1.44

Autoantibodies to nuclear lamin C in the eosinophilia-myalgia syndrome associated with L-tryptophan ingestion. Arthritis Rheum (1992) 1.41

Co-ordinate increase in the expression of type I and type III collagen genes in progressive systemic sclerosis fibroblasts. Biochem J (1986) 1.37

Identification of collagen alpha1(I) trimer in embryonic chick tendons and calvaria. Biochem Biophys Res Commun (1977) 1.36

Structure of cDNA clones coding for human type II procollagen. The alpha 1(II) chain is more similar to the alpha 1(I) chain than two other alpha chains of fibrillar collagens. Biochem J (1989) 1.31

Transcriptional control of human diploid fibroblast collagen synthesis by gamma-interferon. Biochem Biophys Res Commun (1984) 1.27

Mononuclear cellular infiltrates in clinically involved skin from patients with systemic sclerosis of recent onset predominantly consist of monocytes/macrophages. Pathobiology (1995) 1.25

Experimental silicosis: morphologic and biochemical abnormalities produced by intratracheal instillation of quartz into guinea pig lungs. Am J Pathol (1980) 1.25

Systemic sclerosis after augmentation mammoplasty with silicone implants. Ann Intern Med (1989) 1.23

Cell-mediated immunity in interstitial nephritis. III. T lymphocyte-mediated fibroblast proliferation and collagen synthesis: an immune mechanism for renal fibrogenesis. J Immunol (1980) 1.22

Determination of an epitope of the diffuse systemic sclerosis marker antigen DNA topoisomerase I: sequence similarity with retroviral p30gag protein suggests a possible cause for autoimmunity in systemic sclerosis. Proc Natl Acad Sci U S A (1989) 1.21

Differential regulation of cyclooxygenases 1 and 2 by interleukin-1 beta, tumor necrosis factor-alpha, and transforming growth factor-beta 1 in human lung fibroblasts. Exp Cell Res (1998) 1.20

The regulation of lung fibroblast proliferation by alveolar macrophages in experimental silicosis. Am Rev Respir Dis (1984) 1.19

Inhibition of excessive scleroderma fibroblast collagen production by recombinant gamma-interferon. Association with a coordinate decrease in types I and III procollagen messenger RNA levels. Arthritis Rheum (1986) 1.19

Glucosamine sulfate modulates the levels of aggrecan and matrix metalloproteinase-3 synthesized by cultured human osteoarthritis articular chondrocytes. Osteoarthritis Cartilage (2003) 1.19

Biosynthesis of a low molecular weight collagen by rabbit growth plate cartilage organ cultures. Coll Relat Res (1983) 1.18

Regulation of type-II collagen gene expression during human chondrocyte de-differentiation and recovery of chondrocyte-specific phenotype in culture involves Sry-type high-mobility-group box (SOX) transcription factors. Biochem J (2001) 1.17

Modulation of TGF-beta signaling by proinflammatory cytokines in articular chondrocytes. Osteoarthritis Cartilage (2007) 1.16

Phenotype of peripheral blood lymphocytes in patients with progressive systemic sclerosis: activated T lymphocytes and the effect of D-penicillamine therapy. Clin Exp Immunol (1987) 1.15

The Tight skin mouse: demonstration of mutant fibrillin-1 production and assembly into abnormal microfibrils. J Cell Biol (1998) 1.10

Transforming growth factor-beta stimulation of lung fibroblast prostaglandin E2 production. J Biol Chem (1989) 1.10

Formation of nodular structures resembling mature articular cartilage in long-term primary cultures of human fetal epiphyseal chondrocytes on a hydrogel substrate. Arthritis Rheum (1994) 1.10

Intracellular collagen and protocollagen from embryonic tendon cells. J Biol Chem (1973) 1.09

Evaluation of transforming growth factor beta and type I procollagen gene expression in fibrotic skin diseases by in situ hybridization. J Invest Dermatol (1990) 1.09

Activation of expression of genes coding for extracellular matrix proteins in Tat-producing glioblastoma cells. Proc Natl Acad Sci U S A (1992) 1.08

Production of cartilage oligomeric matrix protein (COMP) by cultured human dermal and synovial fibroblasts. Osteoarthritis Cartilage (1998) 1.06

Oral iloprost treatment in patients with Raynaud's phenomenon secondary to systemic sclerosis: a multicenter, placebo-controlled, double-blind study. Arthritis Rheum (1998) 1.05

Regulation of transforming growth factor-beta 1 gene expression by glucocorticoids in normal human T lymphocytes. J Clin Invest (1991) 1.04

Genetic linkage mapping of multiple epiphyseal dysplasia to the pericentromeric region of chromosome 19. Am J Hum Genet (1994) 1.04

Increased expression of type VI collagen genes in systemic sclerosis. Arthritis Rheum (1990) 1.03

Elevated expression of type VII collagen in the skin of patients with systemic sclerosis. Regulation by transforming growth factor-beta. J Clin Invest (1994) 1.03

Topoisomerase I identified by scleroderma 70 antisera: enrichment of topoisomerase I at the centromere in mouse mitotic cells before anaphase. Proc Natl Acad Sci U S A (1986) 1.03

Elevated expression of beta 1 and beta 2 integrins, intercellular adhesion molecule 1, and endothelial leukocyte adhesion molecule 1 in the skin of patients with systemic sclerosis of recent onset. Arthritis Rheum (1992) 1.02

Biosynthetic expression of type X collagen in embryonic chick sternum cartilage during development. J Biol Chem (1986) 1.01

Identification of two new collagen alpha-chains in extracts of lathyritic chick embryo tendons. Biochem Biophys Res Commun (1978) 1.00

Modulation of human alpha1(I) procollagen gene activity by interaction with Sp1 and Sp3 transcription factors in vitro. Gene (1998) 0.98

A pilot study of intermittent intravenous cyclophosphamide for the treatment of systemic sclerosis associated lung disease. J Rheumatol (1998) 0.98

Scleroderma-like alterations in collagen metabolism occurring in the TSK (tight skin) mouse. Arthritis Rheum (1984) 0.98

Exaggerated radiation-induced fibrosis in patients with systemic sclerosis. JAMA (1991) 0.98

Interferon-gamma reverses the stimulation of collagen but not fibronectin gene expression by transforming growth factor-beta in normal human fibroblasts. Eur J Clin Invest (1990) 0.98

Increased sensitivity of scleroderma fibroblasts in culture to stimulation of protein and collagen synthesis by serum. Biochem Biophys Res Commun (1977) 0.97

PGE2 causes a coordinate decrease in the steady state levels of fibronectin and types I and III procollagen mRNAs in normal human dermal fibroblasts. Biochem Biophys Res Commun (1987) 0.97

Recombinant gamma, alpha, and beta interferon regulation of human lung fibroblast proliferation. Am Rev Respir Dis (1987) 0.96

Alternative splicing of human prostaglandin G/H synthase mRNA and evidence of differential regulation of the resulting transcripts by transforming growth factor beta 1, interleukin 1 beta, and tumor necrosis factor alpha. J Biol Chem (1992) 0.96

Polymorphisms in the IL-1 receptor antagonist gene VNTR are possible risk factors for juvenile idiopathic inflammatory myopathies. Clin Exp Immunol (2000) 0.96

Identification of a mutation in type X collagen in a family with Schmid metaphyseal chondrodysplasia. Hum Mol Genet (1994) 0.95

Type X collagen alterations in rachitic chick epiphyseal growth cartilage. J Biol Chem (1988) 0.95

Increased collagen biosynthesis and increased expression of type I and type III procollagen genes in tight skin (TSK) mouse fibroblasts. J Biol Chem (1986) 0.95

Increased biosynthesis of glycosaminoglycans by scleroderma fibroblasts in culture. Arthritis Rheum (1984) 0.95

Effects of interferon-gamma and tumor necrosis factor alpha on the expression of the genes encoding aggrecan, biglycan, and decorin core proteins in cultured human chondrocytes. Arthritis Rheum (1998) 0.94

Positive regulation of human alpha 1 (I) collagen promoter activity by transcription factor Sp1. Gene (1995) 0.94

Impotence in progressively systemic sclerosis. Ann Intern Med (1981) 0.93

Quantitative analysis of type X-collagen biosynthesis by embryonic-chick sternal cartilage. Biochem J (1986) 0.93

Collagen synthesis by scleroderma fibroblasts in culture. Arthritis Rheum (1977) 0.93

Differential regulation of transforming growth factor beta-1 gene expression by glucocorticoids in human T and glial cells. J Immunol (1995) 0.93

Exclusion of type II and type VI procollagen gene mutations in a five-generation family with multiple epiphyseal dysplasia. Am J Med Genet (1993) 0.92

Transcriptional modulation of cartilage-specific collagen gene expression by interferon gamma and tumour necrosis factor alpha in cultured human chondrocytes. Biochem J (1993) 0.92

Influence of prior pregnancies on disease course and cause of death in systemic sclerosis. Ann Rheum Dis (2002) 0.92

Growth properties and biochemical characterization of collagens synthesized by adult rat heart fibroblasts in culture. J Mol Cell Cardiol (1992) 0.92

Biosynthesis of a disulphide-bonded short-chain collagen by calf growth-plate cartilage. Biochem J (1984) 0.91

Modulation of collagen gene expression: its relation to fibrosis in systemic sclerosis and other disorders. Ann Intern Med (1995) 0.91

Esophageal function in systemic sclerosis: a prospective evaluation of motility and acid reflux in 36 patients. Am J Gastroenterol (1993) 0.91

Pulmonary function and gastroesophageal reflux in systemic sclerosis. Ann Intern Med (1994) 0.90

Expression of a human cartilage procollagen gene (COL2A1) in mouse 3T3 cells. J Biol Chem (1991) 0.90

Regulation of human lung fibroblast alpha 1(I) procollagen gene expression by tumor necrosis factor alpha, interleukin-1 beta, and prostaglandin E2. J Biol Chem (1993) 0.90

Fetal-maternal HLA compatibility confers susceptibility to systemic sclerosis. Immunogenetics (1997) 0.89

Familial spondyloepiphyseal dysplasia tarda, brachydactyly, and precocious osteoarthritis associated with an arginine 75-->cysteine mutation in the procollagen type II gene in a kindred of Chiloe Islanders. I. Clinical, radiographic, and pathologic findings. Arthritis Rheum (1994) 0.89

Progressive systemic sclerosis: mode of presentation, rapidly progressive disease course, and mortality based on an analysis of 91 patients. Semin Arthritis Rheum (1988) 0.89

Isolation, characterization, and localization of cardiac collagen type VI. Associations with other extracellular matrix components. Circ Res (1992) 0.88

Changes in collagen biosynthesis, types, and mechanics of aorta in hypertensive rats. J Lab Clin Med (1989) 0.88

Effects of temperature on conformation, hydroxylation, and secretion of chick tendon procollagen. J Biol Chem (1974) 0.88

Clinical spectrum of the systemic manifestations of the eosinophilia-myalgia syndrome. Semin Arthritis Rheum (1990) 0.88

Articular cartilage preservation and storage. I. Application of tissue culture techniques to the storage of viable articular cartilage. Arthritis Rheum (1979) 0.87

Role of molecular conformation on secretion of chick tendon procollagen. J Biol Chem (1978) 0.87

Characterization of pepsin-solubilized bovine heart-valve collagen. Biochem J (1978) 0.87

Heritable diseases of cartilage caused by mutations in collagen genes. J Rheumatol Suppl (1995) 0.87

Modulation of basal expression of the human alpha1(I) procollagen gene (COL1A1) by tandem NF-1/Sp1 promoter elements in normal human dermal fibroblasts. Matrix Biol (1998) 0.86

Detection and characterization of Sp1 binding activity in human chondrocytes and its alterations during chondrocyte dedifferentiation. J Biol Chem (1997) 0.86

CCAAT binding transcription factor binds and regulates human COL1A1 promoter activity in human dermal fibroblasts: demonstration of increased binding in systemic sclerosis fibroblasts. Arthritis Rheum (2000) 0.86

Elevated expression of the genes for transforming growth factor-beta 1 and type VI collagen in diffuse fasciitis associated with the eosinophilia-myalgia syndrome. J Invest Dermatol (1991) 0.86

Inhibition of type I collagen gene expression in normal and systemic sclerosis fibroblasts by a specific inhibitor of geranylgeranyl transferase I. Arthritis Rheum (2000) 0.86

TGF-beta modulates the synthesis of proteoglycans by myocardial fibroblasts in culture. J Mol Cell Cardiol (1995) 0.86

Allograft inflammatory factor-1 and tumor necrosis factor single nucleotide polymorphisms in systemic sclerosis. Tissue Antigens (2007) 0.85

Expression of the basement membrane heparan sulfate proteoglycan (perlecan) in human synovium and in cultured human synovial cells. Lab Invest (1995) 0.85

Isolation and characterization of microvascular endothelial cells from the adult human dermis and from skin biopsies of patients with systemic sclerosis. Lab Invest (1994) 0.85