Published in Biochem J on June 01, 1973
Preparation and properties of mitochondria derived from synaptosomes. Biochem J (1976) 1.51
Differential effects of 2-oxo acids on pyruvate utilization and fatty acid synthesis in rat brain. Biochem J (1974) 1.13
Comparative studies on glutamate metabolism in synpatic and non-synaptic rat brain mitochondria. Biochem J (1977) 0.96
The regulation of glutamate metabolism by tricarboxylic acid-cycle activity in rat brain mitochondria. Biochem J (1978) 0.90
Effect of phenylpyruvate on pyruvate dehydrogenase activity in rat brain mitochondria. Biochem J (1973) 0.87
Regional enzyme development in rat brain. Enzymes of energy metabolism. Biochem J (1984) 0.86
Effect of hyperphenylalaninaemia on lipid synthesis from ketone bodies by rat brain. Biochem J (1976) 0.85
Mechanism of 3-phenylpyruvate-induced insulin release from isolated pancreatic islets. Biochem J (1981) 0.82
Effect of phenylalanine metabolites on the activities of enzymes of ketone-body utilization in brain of suckling rats. Biochem J (1976) 0.80
Regulation of adipose tissue pyruvate dehydrogenase by insulin and other hormones. Biochem J (1971) 4.50
Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection. Am J Physiol (1971) 3.26
The metabolism of rat brain mitochondria. Preparation and characterization. J Biol Chem (1970) 2.37
Phenylpyruvic oligophrenia deficiency of phenylalanine-oxidizing system. Proc Soc Exp Biol Med (1953) 2.30
The purification and properties of the fatty acid synthetase of pigeon liver. J Biol Chem (1965) 1.90
Liver acetyl coenzyme A carboxylase. I. Isolation and cat- alytic properties. J Biol Chem (1968) 1.74
The regulation of triglyceride synthesis and fatty acid synthesis in rat epididymal adipose tissue. Effects of altered dietary and hormonal conditions. Biochem J (1970) 1.59
Comparative studies of the rat and pigeon liver fatty acid synthetases. Arch Biochem Biophys (1968) 1.46
Studies on phenylpyruvic oligophrenia; phenylpyruvic acid content on blood. Proc Soc Exp Biol Med (1952) 1.41
Rat mammary acetyl coenzyme A carboxylase. I. Isolation and characterization. J Biol Chem (1969) 1.18
Purification of rat heart and rat liver citrate synthases. Physical, kinetic, and immunological studies. J Biol Chem (1971) 1.14
Fatty acid synthetase of brain: development, influence of nutritional and hormonal factors and comparison with liver enzyme. J Neurochem (1972) 1.11
Acetyl coenzyme A carboxylase: filamentous nature of the animal enzymes. Science (1969) 1.11
The inhibition of citrate synthase by adenosine triphosphate. Biochim Biophys Acta (1968) 1.11
Inhibition of citrate synthase by succinyl-CoA and other metabolites. FEBS Lett (1971) 1.09
Kinetic studies on the reaction mechanism and the citrate activation of liver acetyl coenzyme A carboxylase. Eur J Biochem (1971) 1.07
Inhibition of sterol synthesis in vitro by metabolites of phenylalanine. Biochim Biophys Acta (1969) 1.03
Acetyl coenzyme A carboxylase. Purification and properties of the bovine adipose tissue enzyme. Biochemistry (1972) 1.00
Regulation of human and rat brain metabolism: inhibitory action of phenylalanine and phenylpyruvate on glycolysis, protein, lipid, DNA, and RNA metabolism. Adv Enzyme Regul (1970) 0.97
Heterogeneity of mitochondria in rat brain. FEBS Lett (1970) 0.93
The effect of phenylpyruvate on pyruvate metabolism in rat brain. Biochem J (1972) 0.93
Possible biochemical model for phenylketonuria. Nature (1972) 0.92
CONTROL OF GLUTAMATE METABOLISM. THE EFFECT OF PYRUVATE. J Neurochem (1965) 0.92
Aromatic acids derived from phenylalanine in the tissues of rats with experimentally induced phenylketonuria-like characteristics. Biochem J (1972) 0.89
Effect of phenylpyruvate on pyruvate dehydrogenase activity in rat brain mitochondria. Biochem J (1973) 0.87
Biochemical studies on phenylketonuria I. Experimental hyperphenylalanemia in the rat. J Biol Chem (1961) 0.85
Cerebral lipid metabolism in experimental hyperphenylalaninaemia: incorporation of 14C-labelled glucose into total lipids. J Neurochem (1970) 0.84
Short communications. Chain-length specificity for termination of atty acid biosynthesis by fatty acid synthetase complexes from lactating rabbit mamary gland and rat liver. Biochem J (1970) 0.79
The effects of phenylpyruvate and hyperphenylalaninemia on incorporation of (6- 3 H)glucose into macromolecules of slices of rat cerebral cortex. J Neurochem (1971) 0.78
The Role of Peroxide in the Biological Effects of Irradiated Broth. J Bacteriol (1948) 6.42
Mitochondrial complex I deficiency in Parkinson's disease. Lancet (1989) 5.72
The Production of Mutations in Staphylococcus aureus by Chemical Treatment of the Substrate. J Bacteriol (1947) 5.22
Mitochondrial complex I deficiency in Parkinson's disease. J Neurochem (1990) 4.03
The Rôle of Mutation and of Selection in the Frequency of Mutants Among Microörganisms Grown on Irradiated Substrate. Proc Natl Acad Sci U S A (1948) 2.55
The metabolism of rat brain mitochondria. Preparation and characterization. J Biol Chem (1970) 2.37
Inhibition of N-acetylaspartate production: implications for 1H MRS studies in vivo. Neuroreport (1996) 2.18
Epizootiology of neoplasms in bony fish of North America. Sci Total Environ (1990) 2.13
Mitochondrial myopathies: clinical and biochemical features of 30 patients with major deletions of muscle mitochondrial DNA. Ann Neurol (1989) 1.88
Energy thresholds in brain mitochondria. Potential involvement in neurodegeneration. J Biol Chem (1998) 1.84
Mitochondrial encephalomyopathies: biochemical studies in two cases revealing defects in the respiratory chain. Brain (1982) 1.80
Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities. J Neurochem (2002) 1.74
A mitochondrial myopathy characterized by a deficiency in reducible cytochrome b. Brain (1977) 1.69
Nitric oxide-mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes. J Neurochem (1994) 1.67
Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's disease. J Neurochem (1990) 1.66
Effect of peroxynitrite on the mitochondrial respiratory chain: differential susceptibility of neurones and astrocytes in primary culture. J Neurochem (1995) 1.66
A rapid method for the preparation of relatively pure metabolically competent synaptosomes from rat brain. Biochem J (1978) 1.64
Possible horizontal transfer of Drosophila genes by the mite Proctolaelaps regalis. Science (1991) 1.61
The diabetic Zucker fatty rat. Proc Soc Exp Biol Med (1983) 1.54
Nitric oxide, mitochondria and neurological disease. Biochim Biophys Acta (1999) 1.52
Diagnostic importance of Clostridium perfringens enterotoxin analysis in recurring enteritis among elderly, chronic care psychiatric patients. J Clin Microbiol (1986) 1.52
Distribution of mRNAs encoding the peroxisome proliferator-activated receptor alpha, beta, and gamma and the retinoid X receptor alpha, beta, and gamma in rat central nervous system. J Neurochem (1998) 1.51
Preparation and properties of mitochondria derived from synaptosomes. Biochem J (1976) 1.51
Toxic effects of human eosinophil products on isolated rat heart cells in vitro. Biochem J (1982) 1.46
Relationship of pili to colonial morphology among pathogenic and nonpathogenic species of Neisseria. Infect Immun (1977) 1.44
Mitochondrial involvement in brain function and dysfunction: relevance to aging, neurodegenerative disorders and longevity. Neurochem Res (2001) 1.42
Synaptic and non-synaptic mitochondria from rat brain: isolation and characterization. J Neurochem (1977) 1.40
Preparation of synaptic and nonsynaptic mitochondria from mammalian brain. Methods Enzymol (1979) 1.39
Synthesis of N-acetyl-L-aspartate by rat brain mitochondria and its involvement in mitochondrial/cytosolic carbon transport. Biochem J (1979) 1.39
Inhibition of nuclear NAD nucleosidase and poly ADP-ribose polymerase activity from rat liver by nicotinamide and 5'-methyl nicotinamide. Biochim Biophys Acta (1971) 1.35
Nitric oxide produced by activated astrocytes rapidly and reversibly inhibits cellular respiration. Neurosci Lett (1995) 1.34
Nitric oxide-mediated mitochondrial damage in the brain: mechanisms and implications for neurodegenerative diseases. J Neurochem (1997) 1.33
Mitochondrial nitric oxide synthase: a ubiquitous regulator of oxidative phosphorylation? Biochem Biophys Res Commun (1996) 1.27
Threshold effects and control of oxidative phosphorylation in nonsynaptic rat brain mitochondria. J Neurochem (1996) 1.26
Ancestral divergence of Rickettsia bellii from the spotted fever and typhus groups of Rickettsia and antiquity of the genus Rickettsia. Int J Syst Bacteriol (1994) 1.25
Botulism in an adult associated with food-borne intestinal infection with Clostridium botulinum. N Engl J Med (1986) 1.24
Reoxygenation-dependent decrease in mitochondrial NADH:CoQ reductase (Complex I) activity in the hypoxic/reoxygenated rat heart. Biochem J (1991) 1.23
Inhibition of pyruvate and beta-hydroxybutyrate oxidation in rat brain mitochondria by phenylpyruvate and alpha-ketoisocaproate. FEBS Lett (1974) 1.22
A mitochondrial myopathy with a deficiency of respiratory chain NADH-CoQ reductase activity. J Neurol Sci (1979) 1.21
Development of mitochondrial energy metabolism in rat brain. Biochem J (1977) 1.16
The development of enzymes of energy metabolism in the brain of a precocial (guinea pig) and non-precocial (rat) species. J Neurochem (1980) 1.15
Nitric oxide-mediated mitochondrial damage: a potential neuroprotective role for glutathione. Free Radic Biol Med (1996) 1.14
Metabolism of rat brain mitochondria. Studies on the potassium ion-stimulated oxidation of pyruvate. Biochem J (1971) 1.14
Differential effects of 2-oxo acids on pyruvate utilization and fatty acid synthesis in rat brain. Biochem J (1974) 1.13
beta-Amyloid fragment 25-35 selectively decreases complex IV activity in isolated mitochondria. FEBS Lett (1999) 1.10
Beta-amyloid fragment 25-35 causes mitochondrial dysfunction in primary cortical neurons. Neurobiol Dis (2002) 1.10
Immunocytochemical evidence for a mitochondrially located nitric oxide synthase in brain and liver. Biochem Biophys Res Commun (1995) 1.10
The activities of nicotinamide mononucleotide adenylyltransferase and of nicotinamide-adenine dinucleotide kinase in the livers of rats subjected to different hormonal treatments. Biochem J (1965) 1.08
X. The Surgical Treatment of Acute Gonorrhoeal Epididymitis by Epididymotomy. Ann Surg (1914) 1.07
Interrelationships between astrocyte function, oxidative stress and antioxidant status within the central nervous system. Prog Neurobiol (1997) 1.07
Carnitine acyltransferase activities in rat brain mitochondria. Bimodal distribution, kinetic constants, regulation by malonyl-CoA and developmental pattern. Biochem J (1985) 1.06
Threshold effects in synaptosomal and nonsynaptic mitochondria from hippocampal CA1 and paramedian neocortex brain regions. J Neurochem (1997) 1.05
Control of the steady-state concentrations of the nicotinamide nucleotides in rat liver. Biochem J (1969) 1.03
Evidence for increased nitric oxide production in multiple sclerosis. J Neurol Neurosurg Psychiatry (1995) 1.03
Energy metabolism of adult astrocytes in vitro. Neuroscience (1996) 1.03
Differential effect of nitric oxide on glutathione metabolism and mitochondrial function in astrocytes and neurones: implications for neuroprotection/neurodegeneration? J Neurochem (2003) 1.03
Peroxynitrite and brain mitochondria: evidence for increased proton leak. J Neurochem (1998) 1.02
The development of tuberculosis in Afro-Asian immigrants. Tubercle (1979) 1.00
Pigment of Nocardia corallina. J Bacteriol (1966) 0.99
Mitochondrial DNA (mtDNA) diseases: correlation of genotype to phenotype. Biochim Biophys Acta (1995) 0.99
Tetrahydrobiopterin deficiency and brain nitric oxide synthase in the hph1 mouse. J Inherit Metab Dis (1995) 0.97
Comparative studies on glutamate metabolism in synpatic and non-synaptic rat brain mitochondria. Biochem J (1977) 0.96
Lipogenesis in the brain of suckling rats. Studies on the mechansim of mitochondrial-cytosolic carbon transfer. Biochem J (1980) 0.96
Investigation into the role of N-acetylaspartate in cerebral osmoregulation. J Neurochem (1995) 0.96
The effect of a toxin from Bacteroides ureolyticus on the mucosal epithelium of human and bovine oviducts. Br J Exp Pathol (1988) 0.95
Selective inhibition of bacterial enzymes by free fatty acids. J Bacteriol (1969) 0.95
Glutamate metabolism and transport in rat brain mitochondria. Biochem J (1976) 0.95
Mechanisms of intracellular calcium regulation in adult astrocytes. Neuroscience (1996) 0.94
Molecular basis of mitochondrial myopathies: polypeptide analysis in complex-I deficiency. Lancet (1988) 0.94
Depletion of brain glutathione is accompanied by impaired mitochondrial function and decreased N-acetyl aspartate concentration. Neurochem Res (1995) 0.93
A method for the rapid separation of soluble and particulate components of rat brain synaptosomes. FEBS Lett (1979) 0.92
Mitochondrial myopathy. Biochemical studies revealing a deficiency of NADH--cytochrome b reductase activity. J Neurol Sci (1981) 0.92
Extracellular N-acetylaspartate in the rat brain: in vivo determination of basal levels and changes evoked by high K+. J Neurochem (1994) 0.92
Mitochondrial myopathies: defects in mitochondrial metabolism in human skeletal muscle. Biochem Soc Trans (1983) 0.92
Variability of Temperature, pH, and Moisture in an Aerobic Composting Process. Appl Environ Microbiol (1979) 0.91
High resolution proton NMR spectroscopy of multiple sclerosis lesions. J Neurochem (1995) 0.91
Early changes in plasma and hepatic free amino acids in partially hepatectomised rats. Biochim Biophys Acta (1972) 0.91
Lactate utilization by isolated cells from early neonatal rat brain. J Neurochem (1991) 0.91
Mitochondrial myopathies: disorders of the respiratory chain and oxidative phosphorylation. J Inherit Metab Dis (1984) 0.90
The regulation of glutamate metabolism by tricarboxylic acid-cycle activity in rat brain mitochondria. Biochem J (1978) 0.90
Synthesis and anti-inflammatory activities of some N-[pyridyl(phenyl)carbonylamino]-tert-butyl/phenyl-1,2,3,6- tetrahydropyridines. Chem Pharm Bull (Tokyo) (1991) 0.90
Induction of morphogenesis in the genus Arthrobacter. J Bacteriol (1975) 0.90
Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria: evidence for a primary involvement of energy depletion. J Neurochem (1994) 0.89
Postnatal development of the complexes of the electron transport chain in synaptic mitochondria from rat brain. Dev Neurosci (1995) 0.89
Nitric-oxide-induced inhibition of glyceraldehyde-3-phosphate dehydrogenase may mediate reduced endothelial cell monolayer integrity in an in vitro model blood-brain barrier. Brain Res (2001) 0.88
Nitric oxide, energy metabolism and neurological disease. Biochem Soc Trans (1997) 0.87
Postnatal development of the complexes of the electron transport chain in isolated rat brain mitochondria. Dev Neurosci (1994) 0.87
Co-culture of neurones with glutathione deficient astrocytes leads to increased neuronal susceptibility to nitric oxide and increased glutamate-cysteine ligase activity. Brain Res (2005) 0.87
Molecular defects of NADH-ubiquinone oxidoreductase (complex I) in mitochondrial diseases. J Bioenerg Biomembr (1988) 0.87
Changes of respiratory chain activity in mitochondrial and synaptosomal fractions isolated from the gerbil brain after graded ischaemia. J Neurochem (1995) 0.87
Energy-metabolizing enzymes in brain regions of adult and aging rats. J Neurochem (1981) 0.87
Effect of phenylpyruvate on pyruvate dehydrogenase activity in rat brain mitochondria. Biochem J (1973) 0.87
Regional enzyme development in rat brain. Enzymes associated with glucose utilization. Biochem J (1984) 0.87
A comparison of the association of Neisseria gonorrhoeae with human and guinea-pig genital mucosa maintained in organ culture. Br J Exp Pathol (1980) 0.86
Evidence for intramitochondrial complementation between deleted and normal mitochondrial DNA in some patients with mitochondrial myopathy. J Neurol Sci (1992) 0.86
Regional enzyme development in rat brain. Enzymes of energy metabolism. Biochem J (1984) 0.86
Reoxygenation of the hypoxic myocardium causes a mitochondrial complex I defect. Biochem Soc Trans (1990) 0.86
The effects in vitro of hypoglycaemia and recovery from anoxia on synaptosomal metabolism. Biochem J (1982) 0.86