Functional effects of neuromelanin and synthetic melanin in model systems.

PubWeight™: 0.90‹?›

🔗 View Article (PMID 16755379)

Published in J Neural Transm (Vienna) on May 05, 2006

Authors

K L Double1

Author Affiliations

1: Prince of Wales Medical Research Institute, Sydney, Australia. K.Double@unsw.edu.au

Articles cited by this

Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease. Nature (1988) 3.12

Brain iron pathways and their relevance to Parkinson's disease. J Neurochem (2001) 1.55

Neuromelanin of the substantia nigra: a neuronal black hole with protective and toxic characteristics. Trends Neurosci (2003) 1.51

Activation of microglia by human neuromelanin is NF-kappaB dependent and involves p38 mitogen-activated protein kinase: implications for Parkinson's disease. FASEB J (2003) 1.43

Neuromelanin in human dopamine neurons: comparison with peripheral melanins and relevance to Parkinson's disease. Prog Neurobiol (2005) 1.37

Ion-exchange and adsorption of Fe(III) by Sepia melanin. Pigment Cell Res (2004) 1.32

Binding of iron to neuromelanin of human substantia nigra and synthetic melanin: an electron paramagnetic resonance spectroscopy study. Free Radic Biol Med (1997) 1.23

Neuromelanin associated redox-active iron is increased in the substantia nigra of patients with Parkinson's disease. J Neurochem (2003) 1.16

The effect of melanin on iron associated decomposition of hydrogen peroxide. Free Radic Biol Med (1988) 1.02

The neuromelanin of human substantia nigra and its interaction with metals. J Neural Transm (Vienna) (2002) 1.00

Is Parkinson's disease a progressive siderosis of substantia nigra resulting in iron and melanin induced neurodegeneration? Acta Neurol Scand Suppl (1989) 0.99

Iron-melanin interaction and lipid peroxidation: implications for Parkinson's disease. J Neurochem (1991) 0.98

The effect of a synthetic neuromelanin on yield of free hydroxyl radicals generated in model systems. Biochim Biophys Acta (1995) 0.98

Iron-binding characteristics of neuromelanin of the human substantia nigra. Biochem Pharmacol (2003) 0.95

Structural characteristics of human substantia nigra neuromelanin and synthetic dopamine melanins. J Neurochem (2000) 0.92

Antioxidant action of neuromelanin: the mechanism of inhibitory effect on lipid peroxidation. Arch Biochem Biophys (1995) 0.84

Residual substantia nigra neuromelanin in Parkinson's disease is cross-linked to alpha-synuclein. Neurochem Int (2003) 0.83

Differential effects of human neuromelanin and synthetic dopamine melanin on neuronal and glial cells. J Neurochem (2005) 0.80

Dopamine-melanin induces apoptosis in PC12 cells; possible implications for the etiology of Parkinson's disease. Neurochem Int (1997) 0.80

The dopamine receptor agonist lisuride attenuates iron-mediated dopaminergic neurodegeneration. Exp Neurol (2003) 0.79

Magnetic investigations of human mesencephalic neuromelanin. Biochim Biophys Acta (2002) 0.78

Q-band EPR investigations of neuromelanin in control and Parkinson's disease patients. Biochim Biophys Acta (2000) 0.77

Selectivity of melaninized nigra-striatal dopamine neurons to degeneration in Parkinson's disease may depend on iron-melanin interaction. J Neural Transm Suppl (1990) 0.76

Lack of toxicity of human neuromelanin to rat brain dopaminergic neurons. Parkinsonism Relat Disord (1996) 0.75