John G Gribben

Author PubWeight™ 152.38‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia. N Engl J Med 2004 7.04
2 Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug. J Clin Invest 2008 3.89
3 Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup Phase III Trial E2997. J Clin Oncol 2007 3.23
4 Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells. Blood 2008 3.19
5 Select high-risk genetic features predict earlier progression following chemoimmunotherapy with fludarabine and rituximab in chronic lymphocytic leukemia: justification for risk-adapted therapy. J Clin Oncol 2005 3.05
6 Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34(-) fraction. Blood 2010 2.72
7 Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia. Blood 2008 2.72
8 T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production. Blood 2012 2.37
9 Chemoimmunotherapy with fludarabine and rituximab produces extended overall survival and progression-free survival in chronic lymphocytic leukemia: long-term follow-up of CALGB study 9712. J Clin Oncol 2011 2.26
10 Chronic lymphocytic leukemia cells induce changes in gene expression of CD4 and CD8 T cells. J Clin Invest 2005 2.15
11 Fertility and sexual function in long-term survivors of haematological malignancy: using patient-reported outcome measures to assess a neglected area of need in the late effects clinic. Br J Haematol 2013 2.06
12 Chronic lymphocytic leukemia B cells of more than 1% of patients express virtually identical immunoglobulins. Blood 2004 2.01
13 Rituximab and CHOP induction therapy for newly diagnosed mantle-cell lymphoma: molecular complete responses are not predictive of progression-free survival. J Clin Oncol 2002 1.98
14 FLT3 mutations in childhood acute lymphoblastic leukemia. Blood 2003 1.91
15 Dietary flavonoids inhibit the anticancer effects of the proteasome inhibitor bortezomib. Blood 2008 1.90
16 Infectious complications associated with alemtuzumab use for lymphoproliferative disorders. Clin Infect Dis 2006 1.78
17 Number of CD4+ cells and location of forkhead box protein P3-positive cells in diagnostic follicular lymphoma tissue microarrays correlates with outcome. J Clin Oncol 2006 1.68
18 Spleen tyrosine kinase is overexpressed and represents a potential therapeutic target in chronic lymphocytic leukemia. Cancer Res 2009 1.65
19 Follicular lymphoma cells induce changes in T-cell gene expression and function: potential impact on survival and risk of transformation. J Clin Oncol 2013 1.63
20 Myeloablative therapy with autologous bone marrow transplantation for follicular lymphoma at the time of second or subsequent remission: long-term follow-up. J Clin Oncol 2007 1.62
21 The microenvironment of AIDS-related diffuse large B-cell lymphoma provides insight into the pathophysiology and indicates possible therapeutic strategies. Blood 2013 1.62
22 E(mu)-TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction. Proc Natl Acad Sci U S A 2009 1.61
23 Chronic lymphocytic leukemia cells induce defective LFA-1-directed T-cell motility by altering Rho GTPase signaling that is reversible with lenalidomide. Blood 2013 1.61
24 Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: establishing a reversible immune evasion mechanism in human cancer. Blood 2012 1.60
25 SNP rs6457327 in the HLA region on chromosome 6p is predictive of the transformation of follicular lymphoma. Blood 2011 1.57
26 Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia. J Clin Oncol 2012 1.56
27 HIV status does not influence outcome in patients with classical Hodgkin lymphoma treated with chemotherapy using doxorubicin, bleomycin, vinblastine, and dacarbazine in the highly active antiretroviral therapy era. J Clin Oncol 2012 1.55
28 Quantitative analysis of minimal residual disease predicts relapse in children with B-lineage acute lymphoblastic leukemia in DFCI ALL Consortium Protocol 95-01. Blood 2007 1.53
29 The role of B7 family molecules in hematologic malignancy. Blood 2012 1.47
30 Follicular lymphoma cells induce T-cell immunologic synapse dysfunction that can be repaired with lenalidomide: implications for the tumor microenvironment and immunotherapy. Blood 2009 1.45
31 Computational identification of CDR3 sequence archetypes among immunoglobulin sequences in chronic lymphocytic leukemia. Leuk Res 2008 1.42
32 Risk categories and refractory CLL in the era of chemoimmunotherapy. Blood 2012 1.41
33 Self-administered, subcutaneous alemtuzumab to treat residual disease in patients with chronic lymphocytic leukemia. Cancer 2010 1.40
34 Predictors of improved progression-free survival after nonmyeloablative allogeneic stem cell transplantation for advanced chronic lymphocytic leukemia. Biol Blood Marrow Transplant 2006 1.34
35 Sequence analysis of clonal immunoglobulin and T-cell receptor gene rearrangements in children with acute lymphoblastic leukemia at diagnosis and at relapse: implications for pathogenesis and for the clinical utility of PCR-based methods of minimal residual disease detection. Blood 2003 1.33
36 Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma. Gastroenterology 2013 1.32
37 Identification of tumor-associated antigens in chronic lymphocytic leukemia by SEREX. Blood 2002 1.31
38 Use of IGHV3-21 in chronic lymphocytic leukemia is associated with high-risk disease and reflects antigen-driven, post-germinal center leukemogenic selection. Blood 2008 1.27
39 Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts. Blood 2009 1.26
40 Transformation of follicular lymphoma to diffuse large B-cell lymphoma may occur by divergent evolution from a common progenitor cell or by direct evolution from the follicular lymphoma clone. Blood 2009 1.24
41 Bortezomib blocks Bax degradation in malignant B cells during treatment with TRAIL. Blood 2007 1.21
42 Acute myeloid leukemia does not deplete normal hematopoietic stem cells but induces cytopenias by impeding their differentiation. Proc Natl Acad Sci U S A 2013 1.17
43 EZH2 mutations are frequent and represent an early event in follicular lymphoma. Blood 2013 1.17
44 Blocking autophagy prevents bortezomib-induced NF-κB activation by reducing I-κBα degradation in lymphoma cells. PLoS One 2012 1.16
45 Extracellular HMGB1 promotes differentiation of nurse-like cells in chronic lymphocytic leukemia. Blood 2014 1.15
46 Poor concordance among nine immunohistochemistry classifiers of cell-of-origin for diffuse large B-cell lymphoma: implications for therapeutic strategies. Clin Cancer Res 2013 1.12
47 T-cell responses against chronic lymphocytic leukemia cells: implications for immunotherapy. Blood 2002 1.12
48 Increased angiogenic sprouting in poor prognosis FL is associated with elevated numbers of CD163+ macrophages within the immediate sprouting microenvironment. Blood 2010 1.12
49 Expression of FOXP3, CD68, and CD20 at diagnosis in the microenvironment of classical Hodgkin lymphoma is predictive of outcome. J Clin Oncol 2012 1.09
50 Combination immunotherapy with rituximab and interleukin 2 in patients with relapsed or refractory follicular non-Hodgkin's lymphoma. Br J Haematol 2002 1.09
51 Outcome of alloanergized haploidentical bone marrow transplantation after ex vivo costimulatory blockade: results of 2 phase 1 studies. Blood 2008 1.07
52 Final results of a multicenter phase 1 study of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia. Leuk Lymphoma 2011 1.03
53 Long-term survival after autologous bone marrow transplantation for follicular lymphoma in first remission. Biol Blood Marrow Transplant 2007 1.02
54 Defining characteristics of classical Hodgkin lymphoma microenvironment T-helper cells. Blood 2013 1.02
55 Loss of imprinting at the 14q32 domain is associated with microRNA overexpression in acute promyelocytic leukemia. Blood 2014 1.01
56 Understanding the immunodeficiency in chronic lymphocytic leukemia: potential clinical implications. Hematol Oncol Clin North Am 2013 1.01
57 Temporal genetic program following B-cell receptor cross-linking: altered balance between proliferation and death in healthy and malignant B cells. Blood 2007 1.01
58 SAGE analysis demonstrates increased expression of TOSO contributing to Fas-mediated resistance in CLL. Blood 2008 1.00
59 Rituximab plus chlorambucil as first-line treatment for chronic lymphocytic leukemia: Final analysis of an open-label phase II study. J Clin Oncol 2014 0.99
60 Immunoglobulin gene segment usage, location and immunogenicity in mutated and unmutated chronic lymphocytic leukaemia. Br J Haematol 2005 0.99
61 Early neutrophil engraftment following autologous BMT provides a functional predictor of long-term hematopoietic reconstitution. Transfusion 2003 0.98
62 Differential regulation of gene expression following CD40 activation of leukemic compared to healthy B cells. Blood 2004 0.97
63 Immune dysfunction in chronic lymphocytic leukemia T cells and lenalidomide as an immunomodulatory drug. Haematologica 2009 0.96
64 Variations of the ataxia telangiectasia mutated gene in patients with chronic lymphocytic leukemia lack substantial impact on progression-free survival and overall survival: a Cancer and Leukemia Group B study. Leuk Lymphoma 2012 0.96
65 GCS-100, a novel galectin-3 antagonist, modulates MCL-1, NOXA, and cell cycle to induce myeloma cell death. Blood 2010 0.95
66 Cutaneous cryptococcosis in Hodgkin lymphoma. Br J Haematol 2013 0.94
67 The role of the tumor microenvironment in hematological malignancies and implication for therapy. Front Biosci 2005 0.93
68 Nonstochastic pairing of immunoglobulin heavy and light chains expressed by chronic lymphocytic leukemia B cells is predicated on the heavy chain CDR3. Blood 2007 0.93
69 Cord blood natural killer cells exhibit impaired lytic immunological synapse formation that is reversed with IL-2 exvivo expansion. J Immunother 2010 0.93
70 Comparable outcome with T-cell-depleted unrelated-donor versus related-donor allogeneic bone marrow transplantation. Biol Blood Marrow Transplant 2002 0.93
71 The microenvironment differentially impairs passive and active immunotherapy in chronic lymphocytic leukaemia - CXCR4 antagonists as potential adjuvants for monoclonal antibodies. Br J Haematol 2010 0.92
72 Stem cell transplantation for non-Hodgkin's lymphoma. Hematol Oncol Clin North Am 2008 0.91
73 Long-term follow-up after reduced-intensity conditioning allogeneic transplantation for acute myeloid leukemia/myelodysplastic syndrome: late CNS relapses despite graft-versus-host disease. J Clin Oncol 2006 0.90
74 Utilization of Ig heavy chain variable, diversity, and joining gene segments in children with B-lineage acute lymphoblastic leukemia: implications for the mechanisms of VDJ recombination and for pathogenesis. Blood 2004 0.90
75 T-cell function in chronic lymphocytic leukaemia. Semin Cancer Biol 2010 0.90
76 Differential and tumor-specific expression of CD160 in B-cell malignancies. Blood 2011 0.89
77 Development of original donor cell leukemia after successful engraftment from a second donor. Blood 2007 0.88
78 Evaluation of the risk of therapy-related MDS/AML after autologous stem cell transplantation. Biol Blood Marrow Transplant 2002 0.88
79 Real-time polymerase chain reaction estimation of bone marrow tumor burden using clonal immunoglobulin heavy chain gene and bcl-1/JH rearrangements in mantle cell lymphoma. Exp Hematol 2002 0.88
80 CD160 signaling mediates PI3K-dependent survival and growth signals in chronic lymphocytic leukemia. Blood 2010 0.87
81 A unique proteomic profile on surface IgM ligation in unmutated chronic lymphocytic leukemia. Blood 2011 0.87
82 Increased proteasomal degradation of Bax is a common feature of poor prognosis chronic lymphocytic leukemia. Blood 2007 0.87
83 Real-time polymerase chain reaction in multiple myeloma: quantitative analysis of tumor contamination of stem cell harvests. Exp Hematol 2002 0.85
84 Sustained complete remission of CLL associated with the use of a Chinese herbal extract: case report and mechanistic analysis. Leuk Res 2003 0.84
85 Demonstration of durable graft versus lymphoma effects in Hodgkin's lymphoma. J Clin Oncol 2011 0.84
86 Oral fludarabine has significant activity in patients with previously untreated chronic lymphocytic leukemia, and leads to increased STAT1 levels in vivo. Leuk Res 2004 0.83
87 Cytotoxic T cells generated against heteroclitic peptides kill primary tumor cells independent of the binding affinity of the native tumor antigen peptide. Blood 2006 0.83
88 Another look at follicular lymphoma: immunophenotypic and molecular analyses identify distinct follicular lymphoma subgroups. Histopathology 2013 0.82
89 Chronic lymphocytic leukemia: an historical perspective. Hematology Am Soc Hematol Educ Program 2008 0.81
90 Flowing cells through pulsed electric fields efficiently purges stem cell preparations of contaminating myeloma cells while preserving stem cell function. Blood 2004 0.81
91 Vaccine therapy and chronic lymphocytic leukaemia. Best Pract Res Clin Haematol 2008 0.81
92 Engraftment of autologous and allogeneic marrow HPCs after myeloablative therapy. Transfusion 2004 0.80
93 Chronic lymphocytic leukemia: an update on biology and treatment. Curr Oncol Rep 2011 0.80
94 Transplantation in chronic lymphocytic leukemia: timing and expectations. Clin Lymphoma Myeloma 2009 0.80
95 Early relapse and refractory disease remain risk factors in the anthracycline and autologous transplant era for patients with relapsed/refractory classical Hodgkin lymphoma: a single centre intention-to-treat analysis. Br J Haematol 2012 0.80
96 Cytotoxic T cell responses against immunoglobulin in malignant and normal B cells: implications for tumor immunity and autoimmunity. Curr Pharm Des 2003 0.80
97 Reverse-engineering the genetic circuitry of a cancer cell with predicted intervention in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A 2012 0.80
98 Immune dysfunction in chronic lymphocytic leukemia: the role for immunotherapy. Curr Pharm Des 2012 0.80
99 Negative immunomagnetic selection of T cells from peripheral blood of presentation AML specimens. J Immunol Methods 2009 0.79
100 Autologous bone marrow transplantation for marginal zone non-Hodgkin's lymphoma. Leuk Lymphoma 2004 0.79
101 T-cell replete fludarabine/cyclophosphamide reduced intensity allogeneic stem cell transplantation for lymphoid malignancies. Br J Haematol 2012 0.78
102 Immune reconstitution in chronic lymphocytic leukemia. Curr Hematol Malig Rep 2012 0.78
103 Long-term survival with low toxicity after allogeneic transplantation for acute myeloid leukaemia and myelodysplasia using non-myeloablative conditioning without T cell depletion. Br J Haematol 2013 0.78
104 Role of autologous stem cell transplantation in chronic lymphocytic leukemia. Curr Opin Hematol 2003 0.78
105 Autografting CLL: the game is over! Blood 2011 0.78
106 Bile acid malabsorption in patients with graft-versus-host disease of the gastrointestinal tract. Br J Haematol 2012 0.77
107 Role of allogeneic hematopoietic stem-cell transplantation in chronic lymphocytic leukemia. J Clin Oncol 2008 0.77
108 Stem cell transplantation in chronic lymphocytic leukaemia - steering a safe course over shifting sands. Best Pract Res Clin Haematol 2010 0.77
109 Generation of functional CLL-specific cord blood CTL using CD40-ligated CLL APC. PLoS One 2012 0.77
110 The outcome of haemopoietic stem cell transplantation in the treatment of lymphoplasmacytic lymphoma in the UK: a British Society Bone Marrow Transplantation study. Hematology 2008 0.77
111 Dangerous power: mitochondria in CLL cells. Blood 2014 0.77
112 Primary refractory T-cell prolymphocytic leukaemia treated with daily administration of Alemtuzumab plus high-dose methylprednisolone. Eur J Haematol 2014 0.76
113 Advances in chimeric antigen receptor immunotherapy for chronic lymphocytic leukemia. Discov Med 2013 0.76
114 Blockade of chemotaxis in graft-versus-host disease. N Engl J Med 2012 0.76
115 Lymphoid neoplasia. Laser-capturing the essence of Hodgkin lymphoma. Blood 2012 0.76
116 The kiss of death in FL. Blood 2011 0.76
117 Myeloablative chemotherapy for chemo-sensitive recurrent follicular lymphoma: potential benefit in second relapse. Haematologica 2012 0.76
118 Interesting times in the diagnosis and treatment of CLL. Oncology (Williston Park) 2009 0.75
119 Less expensive CARs? Cytotherapy 2012 0.75
120 Hanging tough: CMV-specific CD8+ T cells in CLL. Blood 2014 0.75
121 Parenthood in long-term survivors after CHOP with or without etoposide treatment for aggressive lymphoma - response to Meissner et al. Br J Haematol 2014 0.75
122 Immunotherapeutic approaches have the potential to brighten the future not only for patients with del(17p13.1), but for all CLL patients. Oncology (Williston Park) 2012 0.75
123 Stem cell mimicry: key to transformation? Blood 2009 0.75
124 A shot in the arm for radiotherapy. Blood 2013 0.75
125 The 3 Rs in CLL immune dysfunction. Blood 2010 0.75
126 Corrigendum: Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma. Nat Genet 2016 0.75
127 Transplantation in chronic lymphocytic leukemia. Curr Hematol Malig Rep 2007 0.75
128 Distinctive IGH gene segment usage and minimal residual disease detection in infant acute lymphoblastic leukaemias. Br J Haematol 2005 0.75
129 Effective purging of autologous hematopoietic stem cells using anti-B-cell monoclonal antibody-coated high-density microparticles prior to high-dose therapy for patients with non-Hodgkin's lymphoma. Biol Blood Marrow Transplant 2002 0.75
130 Biologic prognostic markers and their application in clinical trials and management of chronic lymphocytic leukaemia patients. Expert Opin Med Diagn 2008 0.75
131 Follicular lymphoma: quantitation of minimal residual disease by PCR of the t(14;18) translocation. Methods Mol Med 2005 0.75