Published in J Cell Sci on June 13, 2006
Telomerase modulates Wnt signalling by association with target gene chromatin. Nature (2009) 3.96
Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly. Cell (2008) 2.20
Telomerase activation in atherosclerosis and induction of telomerase reverse transcriptase expression by inflammatory stimuli in macrophages. Arterioscler Thromb Vasc Biol (2010) 1.70
Multifactorial analysis of predictors of outcome in pediatric intracranial ependymoma. Neuro Oncol (2008) 1.33
Human telomerase acts as a hTR-independent reverse transcriptase in mitochondria. Nucleic Acids Res (2011) 1.21
Dyrk2-associated EDD-DDB1-VprBP E3 ligase inhibits telomerase by TERT degradation. J Biol Chem (2013) 1.11
A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression. Genome Biol (2015) 1.02
Telomere attrition in isolated high-grade prostatic intraepithelial neoplasia and surrounding stroma is predictive of prostate cancer. Neoplasia (2007) 1.00
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Predictors of outcome in an AIEOP series of childhood ependymomas: a multifactorial analysis. Neuro Oncol (2012) 0.89
Telomerase inhibition abolishes the tumorigenicity of pediatric ependymoma tumor-initiating cells. Acta Neuropathol (2014) 0.87
Telomerase expression in the mammalian heart. FASEB J (2012) 0.86
Human telomerase activity, telomerase and telomeric template expression in hepatic stem cells and in livers from fetal and postnatal donors. Eur J Gastroenterol Hepatol (2009) 0.85
Microenvironmental regulation of telomerase isoforms in human embryonic stem cells. Stem Cells Dev (2014) 0.84
Reduced hTERT protein levels are associated with DNA aneuploidy in the colonic mucosa of patients suffering from longstanding ulcerative colitis. Int J Mol Med (2014) 0.84
Specific detection of prostate cancer cells in urine by multiplex immunofluorescence cytology. Hum Pathol (2009) 0.83
Regeneration in pig livers by compensatory hyperplasia induces high levels of telomerase activity. Comp Hepatol (2007) 0.83
hTERT expression in colorectal adenocarcinoma: correlations with p21, p53 expressions and clinicopathological features. Int J Colorectal Dis (2008) 0.82
Medical genetics and epigenetics of telomerase. J Cell Mol Med (2011) 0.82
Role for telomerase in Listeria monocytogenes infection. Infect Immun (2012) 0.79
Predictive value of telomerase reverse transcriptase expression in patients with high risk superficial bladder cancer treated with adjuvant BCG immunotherapy. J Cancer Res Clin Oncol (2009) 0.79
Relationships linking amplification level to gene over-expression in gliomas. PLoS One (2010) 0.78
Senescence evasion in melanoma progression: uncoupling of DNA-damage signaling from p53 activation and p21 expression. Pigment Cell Melanoma Res (2013) 0.77
A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase. PLoS Genet (2015) 0.77
C23 promotes tumorigenesis via suppressing p53 activity. Oncotarget (2016) 0.75
The mouse endometrium contains epithelial, endothelial and leucocyte populations expressing the stem cell marker telomerase reverse transcriptase. Mol Hum Reprod (2016) 0.75
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Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML. Science (2010) 4.52
Interfacial kinetic and binding properties of the complete set of human and mouse groups I, II, V, X, and XII secreted phospholipases A2. J Biol Chem (2002) 2.08
AML1-ETO and C-KIT mutation/overexpression in t(8;21) leukemia: implication in stepwise leukemogenesis and response to Gleevec. Proc Natl Acad Sci U S A (2005) 2.03
Identification and characterization of the human ARD1-NATH protein acetyltransferase complex. Biochem J (2005) 1.96
Pathologically decreased miR-26a antagonizes apoptosis and facilitates carcinogenesis by targeting MTDH and EZH2 in breast cancer. Carcinogenesis (2010) 1.81
MiR-124 targets Slug to regulate epithelial-mesenchymal transition and metastasis of breast cancer. Carcinogenesis (2012) 1.55
Hypoxia-simulating agents and selective stimulation of arsenic trioxide-induced growth arrest and cell differentiation in acute promyelocytic leukemic cells. Haematologica (2005) 1.44
MicroRNA-26b is underexpressed in human breast cancer and induces cell apoptosis by targeting SLC7A11. FEBS Lett (2011) 1.40
Characterization of hARD2, a processed hARD1 gene duplicate, encoding a human protein N-alpha-acetyltransferase. BMC Biochem (2006) 1.30
mTOR signaling pathway is a target for the treatment of colorectal cancer. Ann Surg Oncol (2009) 1.29
Retinoic acid metabolism and mechanism of action: a review. Curr Drug Metab (2003) 1.29
RIG-G as a key mediator of the antiproliferative activity of interferon-related pathways through enhancing p21 and p27 proteins. Proc Natl Acad Sci U S A (2006) 1.28
L-glutamine provides acid resistance for Escherichia coli through enzymatic release of ammonia. Cell Res (2013) 1.21
IRF-9/STAT2 [corrected] functional interaction drives retinoic acid-induced gene G expression independently of STAT1. Cancer Res (2009) 1.18
Hypoxia inducible factor-1 mediates expression of galectin-1: the potential role in migration/invasion of colorectal cancer cells. Carcinogenesis (2010) 1.16
Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells. Nat Chem Biol (2012) 1.15
Expanding the use of arsenic trioxide: leukemias and beyond. Semin Hematol (2002) 1.15
Polyhydroxyalkanoates as a source of chemicals, polymers, and biofuels. Curr Opin Biotechnol (2011) 1.13
Biosynthesis of poly(3-hydroxydecanoate) and 3-hydroxydodecanoate dominating polyhydroxyalkanoates by β-oxidation pathway inhibited Pseudomonas putida. Metab Eng (2010) 1.10
SUMO-specific protease 1 regulates the in vitro and in vivo growth of colon cancer cells with the upregulated expression of CDK inhibitors. Cancer Lett (2011) 1.10
Microbial production of R-3-hydroxybutyric acid by recombinant E. coli harboring genes of phbA, phbB, and tesB. Appl Microbiol Biotechnol (2007) 1.10
Comparative genomics study of polyhydroxyalkanoates (PHA) and ectoine relevant genes from Halomonas sp. TD01 revealed extensive horizontal gene transfer events and co-evolutionary relationships. Microb Cell Fact (2011) 1.09
Comparison of gene expression profiles between primary tumor and metastatic lesions in gastric cancer patients using laser microdissection and cDNA microarray. World J Gastroenterol (2006) 1.09
Induction of tumor arrest and differentiation with prolonged survival by intermittent hypoxia in a mouse model of acute myeloid leukemia. Blood (2005) 1.07
Unsterile and continuous production of polyhydroxybutyrate by Halomonas TD01. Bioresour Technol (2011) 1.05
Adrenomedullin and adrenomedullin binding protein-1 prevent acute lung injury after gut ischemia-reperfusion. J Am Coll Surg (2007) 1.04
In vivo activation of cAMP signaling induces growth arrest and differentiation in acute promyelocytic leukemia. J Exp Med (2002) 1.04
Functional involvement of RINF, retinoid-inducible nuclear factor (CXXC5), in normal and tumoral human myelopoiesis. Blood (2009) 1.04
Targeted genes and interacting proteins of hypoxia inducible factor-1. Int J Biochem Mol Biol (2012) 1.02
Evaluation of three-dimensional scaffolds made of blends of hydroxyapatite and poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) for bone reconstruction. Biomaterials (2005) 1.02
Medical application of microbial biopolyesters polyhydroxyalkanoates. Artif Cells Blood Substit Immobil Biotechnol (2009) 1.02
Type 3 repeat/C-terminal domain of thrombospondin-1 triggers caspase-independent cell death through CD47/alphavbeta3 in promyelocytic leukemia NB4 cells. Blood (2005) 1.01
Combined effects of As4S4 and imatinib on chronic myeloid leukemia cells and BCR-ABL oncoprotein. Blood (2004) 1.01
Treatment of acute promyelocytic leukemia with ATRA and As2O3: a model of molecular target-based cancer therapy. Cancer Biol Ther (2003) 1.00
Biosynthesis and characterization of poly(3-hydroxydodecanoate) by β-oxidation inhibited mutant of Pseudomonas entomophila L48. Biomacromolecules (2011) 0.99
Thioesterase II of Escherichia coli plays an important role in 3-hydroxydecanoic acid production. Appl Environ Microbiol (2004) 0.99
A novel self-cleaving phasin tag for purification of recombinant proteins based on hydrophobic polyhydroxyalkanoate nanoparticles. Lab Chip (2008) 0.99
Function and histopathology of a cell adhesion molecule TSLC1 in cancer. Cancer Invest (2011) 0.98
Fabrication of nano-hydroxyapatite on electrospun silk fibroin nanofiber and their effects in osteoblastic behavior. J Biomed Mater Res A (2011) 0.98
Differentiation of human bone marrow mesenchymal stem cells grown in terpolyesters of 3-hydroxyalkanoates scaffolds into nerve cells. Biomaterials (2009) 0.98
Synergic effects of arsenic trioxide and cAMP during acute promyelocytic leukemia cell maturation subtends a novel signaling cross-talk. Blood (2002) 0.98
Post-ischemic hypothermia for 24h in P7 rats rescues hippocampal neuron: association with decreased astrocyte activation and inflammatory cytokine expression. Brain Res Bull (2009) 0.97
Downregulation of ANP32B, a novel substrate of caspase-3, enhances caspase-3 activation and apoptosis induction in myeloid leukemic cells. Carcinogenesis (2009) 0.97
Tissue-transglutaminase contributes to neutrophil granulocyte differentiation and functions. Blood (2006) 0.97
Crucial role of copper in detection of metal-coordinating odorants. Proc Natl Acad Sci U S A (2012) 0.96
Expression of anion exchanger 1 sequestrates p16 in the cytoplasm in gastric and colonic adenocarcinoma. Neoplasia (2007) 0.96
Overexpression of NAD kinase in recombinant Escherichia coli harboring the phbCAB operon improves poly(3-hydroxybutyrate) production. Appl Microbiol Biotechnol (2009) 0.96
Nanofibrous polyhydroxyalkanoate matrices as cell growth supporting materials. Biomaterials (2008) 0.95
Synthesis of Diblock copolymer poly-3-hydroxybutyrate -block-poly-3-hydroxyhexanoate [PHB-b-PHHx] by a β-oxidation weakened Pseudomonas putida KT2442. Microb Cell Fact (2012) 0.95
Effect of surface treatment on the biocompatibility of microbial polyhydroxyalkanoates. Biomaterials (2002) 0.94
Pharicin B stabilizes retinoic acid receptor-α and presents synergistic differentiation induction with ATRA in myeloid leukemic cells. Blood (2010) 0.94
Evaluation of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) conduits for peripheral nerve regeneration. Biomaterials (2008) 0.94
A specific drug targeting system based on polyhydroxyalkanoate granule binding protein PhaP fused with targeted cell ligands. Biomaterials (2008) 0.93
Proteomics-based identification of two novel direct targets of hypoxia-inducible factor-1 and their potential roles in migration/invasion of cancer cells. Proteomics (2009) 0.93
Prediction of pancreatic cancer by serum biomarkers using surface-enhanced laser desorption/ionization-based decision tree classification. Oncology (2005) 0.93
Protein kinase cδ in apoptosis: a brief overview. Arch Immunol Ther Exp (Warsz) (2012) 0.93
c-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expression. Nat Cell Biol (2012) 0.92
Tankyrase 1 regulates centrosome function by controlling CPAP stability. EMBO Rep (2012) 0.92
Production of polyhydroxyalkanoates with high 3-hydroxydodecanoate monomer content by fadB and fadA knockout mutant of Pseudomonas putida KT2442. Biomacromolecules (2007) 0.92
Interferon-alpha-induced expression of phospholipid scramblase 1 through STAT1 requires the sequential activation of protein kinase Cdelta and JNK. J Biol Chem (2005) 0.92
The improvement of fibroblast growth on hydrophobic biopolyesters by coating with polyhydroxyalkanoate granule binding protein PhaP fused with cell adhesion motif RGD. Biomaterials (2010) 0.92
A transferable heterogeneous two-hybrid system in Escherichia coli based on polyhydroxyalkanoates synthesis regulatory protein PhaR. Microb Cell Fact (2011) 0.91
Application of polyhydroxyalkanoates nanoparticles as intracellular sustained drug-release vectors. J Biomater Sci Polym Ed (2010) 0.91
Direct interaction and cooperative role of tumor suppressor p16 with band 3 (AE1). FEBS Lett (2005) 0.91
Attachment, proliferation and differentiation of osteoblasts on random biopolyester poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) scaffolds. Biomaterials (2004) 0.90
Protein kinase C-delta mediates down-regulation of heterogeneous nuclear ribonucleoprotein K protein: involvement in apoptosis induction. Exp Cell Res (2009) 0.90
Hyperproduction of poly(4-hydroxybutyrate) from glucose by recombinant Escherichia coli. Microb Cell Fact (2012) 0.90
Apoptosome-independent pathway for apoptosis. Biochemical analysis of APAF-1 defects and biological outcomes. J Biol Chem (2003) 0.90
Microbial production of 3-hydroxydodecanoic acid by pha operon and fadBA knockout mutant of Pseudomonas putida KT2442 harboring tesB gene. Appl Microbiol Biotechnol (2009) 0.90
The behaviour of neural stem cells on polyhydroxyalkanoate nanofiber scaffolds. Biomaterials (2010) 0.90
Polyhydroxyalkanoate synthases PhaC1 and PhaC2 from Pseudomonas stutzeri 1317 had different substrate specificities. FEMS Microbiol Lett (2004) 0.89
Leukemogenic AML1-ETO fusion protein upregulates expression of connexin 43: the role in AML 1-ETO-induced growth arrest in leukemic cells. J Cell Physiol (2006) 0.89
Construction of eukaryotic expression vector of TSLC1 gene. Arch Med Sci (2011) 0.89
Production and characterization of poly(3-hydroxypropionate-co-4-hydroxybutyrate) with fully controllable structures by recombinant Escherichia coli containing an engineered pathway. Metab Eng (2012) 0.89
Three-Dimensional Printing in Orthopedic Surgery. Orthopedics (2015) 0.89
Poly(hydroxybutyrate-co-hydroxyhexanoate) promoted production of extracellular matrix of articular cartilage chondrocytes in vitro. Biomaterials (2003) 0.89
Reduced mouse fibroblast cell growth by increased hydrophilicity of microbial polyhydroxyalkanoates via hyaluronan coating. Biomaterials (2003) 0.88
The effect of 3-hydroxybutyrate and its derivatives on the growth of glial cells. Biomaterials (2007) 0.88
Microbial production of meso-2,3-butanediol by metabolically engineered Escherichia coli under low oxygen condition. Appl Microbiol Biotechnol (2010) 0.88
Biosynthesis of polyhydroxyalkanoate homopolymers by Pseudomonas putida. Appl Microbiol Biotechnol (2010) 0.88
The effect of D,L-beta-hydroxybutyric acid on cell death and proliferation in L929 cells. Biomaterials (2006) 0.88
Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling. J Cell Mol Med (2009) 0.88
Effects of crystallization of polyhydroxyalkanoate blend on surface physicochemical properties and interactions with rabbit articular cartilage chondrocytes. Biomaterials (2005) 0.88
Production of polyhydroxyalkanoates by Escherichia coli mutants with defected mixed acid fermentation pathways. Appl Microbiol Biotechnol (2010) 0.88
Death receptor signaling regulatory function for telomerase: hTERT abolishes TRAIL-induced apoptosis, independently of telomere maintenance. Oncogene (2004) 0.88