In men, peripheral estradiol levels directly reflect the action of estrogens at the hypothalamo-pituitary level to inhibit gonadotropin secretion.

PubWeight™: 1.02‹?› | Rank: Top 15%

🔗 View Article (PMID 16787981)

Published in J Clin Endocrinol Metab on June 20, 2006

Authors

Garrett Raven1, Frank H de Jong, Jean-Marc Kaufman, Willem de Ronde

Author Affiliations

1: Department of Endocrinology, VU University Medical Center, de Boelelaan 1117, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands.

Articles citing this

A randomized pilot trial of growth hormone with anastrozole versus growth hormone alone, starting at the very end of puberty in adolescents with idiopathic short stature. Int J Pediatr Endocrinol (2015) 1.44

Endocrine-disrupting chemicals: associated disorders and mechanisms of action. J Environ Public Health (2012) 1.40

Advances in male contraception. Endocr Rev (2008) 1.39

Inhibition of luteinizing hormone secretion by testosterone in men requires aromatization for its pituitary but not its hypothalamic effects: evidence from the tandem study of normal and gonadotropin-releasing hormone-deficient men. J Clin Endocrinol Metab (2007) 1.13

Treatment of male infertility secondary to morbid obesity. Nat Clin Pract Endocrinol Metab (2008) 0.96

Genetic variations in sex steroid-related genes as predictors of serum estrogen levels in men. J Clin Endocrinol Metab (2008) 0.95

Increases in bone mineral density in response to oral dehydroepiandrosterone replacement in older adults appear to be mediated by serum estrogens. J Clin Endocrinol Metab (2008) 0.92

Localization of breast cancer resistance protein (Bcrp) in endocrine organs and inhibition of its transport activity by steroid hormones. Cell Tissue Res (2012) 0.92

Aromatase inhibitors in men: effects and therapeutic options. Reprod Biol Endocrinol (2011) 0.88

Increased basal and pulsatile secretion of FSH and LH in young men with 47,XXY or 46,XX karyotypes. Eur J Endocrinol (2008) 0.79

Aromatase Inhibition Reduces Insulin Sensitivity in Healthy Men. J Clin Endocrinol Metab (2016) 0.76

Determinants of testosterone levels in human male obesity. Endocrine (2015) 0.76

Aging and estradiol effects on gene expression in the medial preoptic area, bed nucleus of the stria terminalis, and posterodorsal medial amygdala of male rats. Mol Cell Endocrinol (2016) 0.75

Testosterone replacement in the infertile man. Transl Androl Urol (2016) 0.75

Estradiol-modified prolactin secretion independently of action potentials and Ca(2+) and blockade of outward potassium currents in GH3 cells. Naunyn Schmiedebergs Arch Pharmacol (2016) 0.75

Articles by these authors

Intravenous zoledronic acid in postmenopausal women with low bone mineral density. N Engl J Med (2002) 5.83

Fracture risk and zoledronic acid therapy in men with osteoporosis. N Engl J Med (2012) 3.51

Lower testosterone levels with luteinizing hormone-releasing hormone agonist therapy than with surgical castration: new insights attained by mass spectrometry. J Urol (2012) 3.28

Anti-Müllerian hormone levels in the spontaneous menstrual cycle do not show substantial fluctuation. J Clin Endocrinol Metab (2006) 3.13

Antimüllerian hormone serum levels: a putative marker for ovarian aging. Fertil Steril (2002) 3.03

Estrogen receptor alpha gene polymorphisms and risk of myocardial infarction. JAMA (2004) 2.93

Serum antimullerian hormone levels best reflect the reproductive decline with age in normal women with proven fertility: a longitudinal study. Fertil Steril (2005) 2.90

Low levels of endogenous androgens increase the risk of atherosclerosis in elderly men: the Rotterdam study. J Clin Endocrinol Metab (2002) 2.76

Anti-müllerian hormone is a promising predictor for the occurrence of the menopausal transition. Menopause (2004) 2.69

Anti-Müllerian hormone: a new marker for ovarian function. Reproduction (2006) 2.49

Endogenous testosterone and cardiovascular disease in healthy men: a meta-analysis. Heart (2010) 2.42

Evidence of limited contributions for intratumoral steroidogenesis in prostate cancer. Cancer Res (2010) 2.39

Association of the ER22/23EK polymorphism in the glucocorticoid receptor gene with survival and C-reactive protein levels in elderly men. Am J Med (2004) 1.93

Identification of the BclI polymorphism in the glucocorticoid receptor gene: association with sensitivity to glucocorticoids in vivo and body mass index. Clin Endocrinol (Oxf) (2003) 1.83

Predictors of poor ovarian response in in vitro fertilization: a prospective study comparing basal markers of ovarian reserve. Fertil Steril (2002) 1.78

High prevalence of central adrenal insufficiency in patients with Prader-Willi syndrome. J Clin Endocrinol Metab (2008) 1.77

A polymorphism in the glucocorticoid receptor gene, which decreases sensitivity to glucocorticoids in vivo, is associated with low insulin and cholesterol levels. Diabetes (2002) 1.55

Adverse reactions and drug-drug interactions in the management of women with postmenopausal osteoporosis. Calcif Tissue Int (2011) 1.50

Adrenal insufficiency in meningococcal sepsis: bioavailable cortisol levels and impact of interleukin-6 levels and intubation with etomidate on adrenal function and mortality. J Clin Endocrinol Metab (2005) 1.49

One single dose of etomidate negatively influences adrenocortical performance for at least 24h in children with meningococcal sepsis. Intensive Care Med (2007) 1.46

Genetic determinants of serum testosterone concentrations in men. PLoS Genet (2011) 1.45

Anti-Mullerian hormone is a sensitive serum marker for gonadal function in women treated for Hodgkin's lymphoma during childhood. J Clin Endocrinol Metab (2007) 1.42

Biochemical endocrinology of the hypogonadal male. Ann Clin Biochem (2010) 1.40

Anti-Mullerian hormone, inhibin B, and antral follicle count in young women with ovarian failure. J Clin Endocrinol Metab (2008) 1.39

Serum anti-mullerian hormone levels reflect the size of the primordial follicle pool in mice. Endocrinology (2006) 1.39

Loss of ovarian reserve after uterine artery embolization: a randomized comparison with hysterectomy. Hum Reprod (2007) 1.33

Changes in anti-Müllerian hormone serum concentrations over time suggest delayed ovarian ageing in normogonadotrophic anovulatory infertility. Hum Reprod (2004) 1.32

Relationship between bone mineral density changes and fracture risk reduction in patients treated with strontium ranelate. J Clin Endocrinol Metab (2007) 1.32

Pasireotide alone or with cabergoline and ketoconazole in Cushing's disease. N Engl J Med (2010) 1.32

The activin A-follistatin system: potent regulator of human extracellular matrix mineralization. FASEB J (2007) 1.31

Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms. PLoS Genet (2011) 1.30

Glucocorticoid receptor gene and risk of cardiovascular disease. Arch Intern Med (2008) 1.25

Anti-Müllerian hormone and anti-Müllerian hormone type II receptor polymorphisms are associated with follicular phase estradiol levels in normo-ovulatory women. Hum Reprod (2007) 1.23

Endogenous sex hormones, sex hormone-binding globulin, and the risk of incident vertebral fractures in elderly men and women: the Rotterdam Study. J Clin Endocrinol Metab (2004) 1.23

A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. PLoS Genet (2012) 1.23

Fat mass rather than muscle strength is the major determinant of physical function and disability in postmenopausal women younger than 75 years of age. Menopause (2006) 1.19

Quality of life in sarcopenia and frailty. Calcif Tissue Int (2013) 1.17

Increased oocyte degeneration and follicular atresia during the estrous cycle in anti-Müllerian hormone null mice. Endocrinology (2007) 1.15

A functional anti-mullerian hormone gene polymorphism is associated with follicle number and androgen levels in polycystic ovary syndrome patients. J Clin Endocrinol Metab (2008) 1.12

Two polymorphisms in the glucocorticoid receptor gene directly affect glucocorticoid-regulated gene expression. J Clin Endocrinol Metab (2005) 1.09

Estrogen receptor alpha gene polymorphisms are associated with estradiol levels in postmenopausal women. Eur J Endocrinol (2005) 1.09

Triiodothyronine and free thyroxine levels are differentially associated with metabolic profile and adiposity-related cardiovascular risk markers in euthyroid middle-aged subjects. Thyroid (2013) 1.08

Glucocorticoid receptor polymorphism affects transrepression but not transactivation. J Clin Endocrinol Metab (2006) 1.07

The association of sex hormone levels with quantitative ultrasound, bone mineral density, bone turnover and osteoporotic fractures in older men and women. Clin Endocrinol (Oxf) (2007) 1.07

Endocrine aspects of sexual dysfunction in men. J Sex Med (2004) 1.06

Development of a highly sensitive method for the quantification of estrone and estradiol in serum by liquid chromatography tandem mass spectrometry without derivatization. J Chromatogr B Analyt Technol Biomed Life Sci (2012) 1.06

The effects of a pedometer-based behavioral modification program with telephone support on physical activity and sedentary behavior in type 2 diabetes patients. Patient Educ Couns (2010) 1.05

Evidence from data searches and life-table analyses for gender-related differences in absolute risk of hip fracture after Colles' or spine fracture: Colles' fracture as an early and sensitive marker of skeletal fragility in white men. J Bone Miner Res (2004) 1.02

Shift work at young age is associated with elevated long-term cortisol levels and body mass index. J Clin Endocrinol Metab (2011) 1.02

Divergences in insulin resistance between the different phenotypes of the polycystic ovary syndrome. J Clin Endocrinol Metab (2013) 1.02

Beneficial and adverse effects of testosterone on the cardiovascular system in men. J Clin Endocrinol Metab (2013) 1.01

Isolated 17,20-lyase deficiency due to the cytochrome b5 mutation W27X. J Clin Endocrinol Metab (2010) 1.01

Fat mass is negatively associated with cortical bone size in young healthy male siblings. J Clin Endocrinol Metab (2009) 1.00

Endogenous estradiol and risk of dementia in women and men: the Rotterdam Study. Ann Neurol (2003) 1.00

FSH receptor genotype is associated with pregnancy but not with ovarian response in IVF. Reprod Biomed Online (2006) 0.99

Body composition and metabolic parameters are associated with variation in thyroid hormone levels among euthyroid young men. Eur J Endocrinol (2012) 0.99

Evidence-based guidelines for the prevention and treatment of glucocorticoid-induced osteoporosis: a consensus document of the Belgian Bone Club. Osteoporos Int (2005) 0.99

Thyroid hormone status within the physiological range affects bone mass and density in healthy men at the age of peak bone mass. Eur J Endocrinol (2011) 0.98

Increased expression of the glucocorticoid receptor-A translational isoform as a result of the ER22/23EK polymorphism. Mol Endocrinol (2005) 0.98

Major surgery within the first 3 months of life and subsequent biobehavioral pain responses to immunization at later age: a case comparison study. Pediatrics (2003) 0.98

Heritability of blood concentrations of sex-steroids in relation to body composition in young adult male siblings. Clin Endocrinol (Oxf) (2008) 0.97

Determinants of vitamin D status in young children: results from the Belgian arm of the IDEFICS (Identification and Prevention of Dietary- and Lifestyle-Induced Health Effects in Children and Infants) Study. Public Health Nutr (2011) 0.97

The results of CHD7 analysis in clinically well-characterized patients with Kallmann syndrome. J Clin Endocrinol Metab (2012) 0.97

Endogenous oestrogens are related to cognition in healthy elderly women. Clin Endocrinol (Oxf) (2005) 0.97

The association of serum testosterone levels and ventricular repolarization. Eur J Epidemiol (2009) 0.96

Inhibin B: a novel marker of spermatogenesis. Ann Med (2003) 0.96

Fetal microchimeric cells in blood of women with an autoimmune thyroid disease. PLoS One (2011) 0.96

Inhibin B is superior to FSH as a serum marker for spermatogenesis in men treated for Hodgkin's lymphoma with chemotherapy during childhood. Hum Reprod (2007) 0.96

Differential regulation of synthetic glucocorticoids on gene expression levels of glucocorticoid-induced leucine zipper and interleukin-2. J Clin Endocrinol Metab (2005) 0.95

Use of ovarian reserve tests for the prediction of ongoing pregnancy in couples with unexplained or mild male infertility. Reprod Biomed Online (2006) 0.95

Dietary intervention in prostate cancer patients: PSA response in a randomized double-blind placebo-controlled study. Int J Cancer (2005) 0.95

Organic anion transporter 1B1: an important factor in hepatic thyroid hormone and estrogen transport and metabolism. Endocrinology (2008) 0.95

Physical function measurements predict mortality in ambulatory older men. Eur J Clin Invest (2013) 0.95

The catechol-O-methyltransferase Met158 low-activity allele and association with nonvertebral fracture risk in elderly men. J Clin Endocrinol Metab (2007) 0.94

Comparative assessment in young and elderly men of the gonadotropin response to aromatase inhibition. J Clin Endocrinol Metab (2005) 0.94

Steroidogenesis vs. steroid uptake in the heart: do corticosteroids mediate effects via cardiac mineralocorticoid receptors? J Hypertens (2010) 0.94

Associations between promoter usage and alternative splicing of the glucocorticoid receptor gene. J Mol Endocrinol (2007) 0.93

Five years treatment with strontium ranelate reduces vertebral and nonvertebral fractures and increases the number and quality of remaining life-years in women over 80 years of age. Bone (2009) 0.93

A common polymorphism in the CYP3A7 gene is associated with a nearly 50% reduction in serum dehydroepiandrosterone sulfate levels. J Clin Endocrinol Metab (2005) 0.93

Long-term effects of irradiation before adulthood on reproductive function in the male rhesus monkey. Biol Reprod (2002) 0.93

Arterial stiffness in postmenopausal women: determinants of pulse wave velocity. J Hypertens (2002) 0.92

Once-yearly zoledronic acid in older men compared with women with recent hip fracture. J Am Geriatr Soc (2011) 0.92

Geographical variation in DXA bone mineral density in young European men and women. Results from the Network in Europe on Male Osteoporosis (NEMO) study. Bone (2008) 0.91

Testicular failure in boys with Prader-Willi syndrome: longitudinal studies of reproductive hormones. J Clin Endocrinol Metab (2011) 0.91

Duration of breastfeeding and gender are associated with methylation of the LEPTIN gene in very young children. Pediatr Res (2013) 0.91

The importance of oestrogens in males. Clin Endocrinol (Oxf) (2003) 0.91

Glucocorticoid receptor mRNA levels are selectively decreased in neutrophils of children with sepsis. Intensive Care Med (2009) 0.90

Serum estradiol is associated with volumetric BMD and modulates the impact of physical activity on bone size at the age of peak bone mass: a study in healthy male siblings. J Bone Miner Res (2009) 0.90

The role of testosterone in aggressive and non-aggressive risk-taking in adolescent boys. Horm Behav (2007) 0.89

The phenotype of polycystic ovary syndrome ameliorates with aging. Fertil Steril (2011) 0.89

Higher estrogen levels are not associated with larger hippocampi and better memory performance. Arch Neurol (2003) 0.89

Variants in the ACVR1 gene are associated with AMH levels in women with polycystic ovary syndrome. Hum Reprod (2008) 0.89

Vitamin D binding protein, bone status and body composition in community-dwelling elderly men. Bone (2005) 0.89

Bivariate association analysis in selected samples: application to a GWAS of two bone mineral density phenotypes in males with high or low BMD. Eur J Hum Genet (2011) 0.89

Characterization of a promoter polymorphism in the glucocorticoid receptor gene and its relationship to three other polymorphisms. Clin Endocrinol (Oxf) (2004) 0.88

Mediators of physical activity change in a behavioral modification program for type 2 diabetes patients. Int J Behav Nutr Phys Act (2011) 0.88

Activin A stimulates AKR1C3 expression and growth in human prostate cancer. Endocrinology (2012) 0.88

Aromatase inhibitors in men: effects and therapeutic options. Reprod Biol Endocrinol (2011) 0.88

Associations of sex-hormone-binding globulin (SHBG) with non-SHBG-bound levels of testosterone and estradiol in independently living men. J Clin Endocrinol Metab (2004) 0.88