Published in Development on July 01, 2006
An evolutionary conserved function of the JAK-STAT pathway in anti-dengue defense. Proc Natl Acad Sci U S A (2009) 2.70
Simulation-based model selection for dynamical systems in systems and population biology. Bioinformatics (2009) 2.27
Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways. Proc Natl Acad Sci U S A (2010) 2.16
The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regeneration. Development (2010) 1.93
Signaling mechanisms controlling cell fate and embryonic patterning. Cold Spring Harb Perspect Biol (2012) 1.89
Canonical and non-canonical JAK-STAT signaling. Trends Cell Biol (2008) 1.85
A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling. Nat Genet (2009) 1.82
JAK-STAT signal inhibition regulates competition in the Drosophila testis stem cell niche. Science (2009) 1.81
Characterization of differentiated quiescent and nonquiescent cells in yeast stationary-phase cultures. Mol Biol Cell (2008) 1.75
The STAT pathway mediates late-phase immunity against Plasmodium in the mosquito Anopheles gambiae. Cell Host Microbe (2009) 1.71
The adult Drosophila malpighian tubules are maintained by multipotent stem cells. Cell Stem Cell (2007) 1.70
The stem cell niche: lessons from the Drosophila testis. Development (2011) 1.67
chinmo is a functional effector of the JAK/STAT pathway that regulates eye development, tumor formation, and stem cell self-renewal in Drosophila. Dev Cell (2010) 1.67
Dedifferentiating spermatogonia outcompete somatic stem cells for niche occupancy in the Drosophila testis. Cell Stem Cell (2009) 1.61
The adult Drosophila gastric and stomach organs are maintained by a multipotent stem cell pool at the foregut/midgut junction in the cardia (proventriculus). Cell Cycle (2011) 1.57
Massively parallel pyrosequencing-based transcriptome analyses of small brown planthopper (Laodelphax striatellus), a vector insect transmitting rice stripe virus (RSV). BMC Genomics (2010) 1.57
The functions of signal transducers and activators of transcriptions 1 and 3 as cytokine-inducible proteins. J Interferon Cytokine Res (2010) 1.48
Drosophila STAT is required for directly maintaining HP1 localization and heterochromatin stability. Nat Cell Biol (2008) 1.47
JAK-STAT is restrained by Notch to control cell proliferation of the Drosophila intestinal stem cells. J Cell Biochem (2010) 1.41
Drosophila follicle cells: morphogenesis in an eggshell. Semin Cell Dev Biol (2008) 1.36
Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation. Structure (2007) 1.35
Mechanisms of cell competition: themes and variations. J Cell Biol (2013) 1.35
False negative rates in Drosophila cell-based RNAi screens: a case study. BMC Genomics (2011) 1.34
Secreted Vago restricts West Nile virus infection in Culex mosquito cells by activating the Jak-STAT pathway. Proc Natl Acad Sci U S A (2012) 1.29
The JAK/STAT pathway positively regulates DPP signaling in the Drosophila germline stem cell niche. J Cell Biol (2008) 1.28
Regulation of circadian behavioral output via a MicroRNA-JAK/STAT circuit. Cell (2012) 1.27
Systems-wide analysis of a phosphatase knock-down by quantitative proteomics and phosphoproteomics. Mol Cell Proteomics (2009) 1.26
Group choreography: mechanisms orchestrating the collective movement of border cells. Nat Rev Mol Cell Biol (2012) 1.25
Heterochromatin formation promotes longevity and represses ribosomal RNA synthesis. PLoS Genet (2012) 1.20
A short receptor downregulates JAK/STAT signalling to control the Drosophila cellular immune response. PLoS Biol (2010) 1.20
Gut microbiota of the tick vector Ixodes scapularis modulate colonization of the Lyme disease spirochete. Cell Host Microbe (2014) 1.19
Evolution of shape by multiple regulatory changes to a growth gene. Science (2012) 1.19
The Drosophila SH2B family adaptor Lnk acts in parallel to chico in the insulin signaling pathway. PLoS Genet (2009) 1.17
Activated STAT regulates growth and induces competitive interactions independently of Myc, Yorkie, Wingless and ribosome biogenesis. Development (2012) 1.16
Genomic RNAi screening in Drosophila S2 cells: what have we learned about host-pathogen interactions? Curr Opin Microbiol (2008) 1.15
The NS3 protein of rice hoja blanca virus complements the RNAi suppressor function of HIV-1 Tat. EMBO Rep (2009) 1.13
Comprehensive meta-analysis of Signal Transducers and Activators of Transcription (STAT) genomic binding patterns discerns cell-specific cis-regulatory modules. BMC Genomics (2013) 1.12
The Jak/STAT pathway. Cold Spring Harb Perspect Biol (2012) 1.11
Massively parallel RNA sequencing identifies a complex immune gene repertoire in the lophotrochozoan Mytilus edulis. PLoS One (2012) 1.07
Identification of JAK/STAT pathway regulators--insights from RNAi screens. Semin Cell Dev Biol (2008) 1.06
Competitiveness for the niche and mutual dependence of the germline and somatic stem cells in the Drosophila testis are regulated by the JAK/STAT signaling. J Cell Physiol (2010) 1.06
Genome-wide expression profiling in the Drosophila eye reveals unexpected repression of notch signaling by the JAK/STAT pathway. Dev Dyn (2009) 1.06
Unphosphorylated STAT and heterochromatin protect genome stability. FASEB J (2010) 1.05
Transcriptome analysis of Aedes aegypti transgenic mosquitoes with altered immunity. PLoS Pathog (2011) 1.04
The Plasmodium bottleneck: malaria parasite losses in the mosquito vector. Mem Inst Oswaldo Cruz (2014) 1.04
Hedgehog is required for CySC self-renewal but does not contribute to the GSC niche in the Drosophila testis. Development (2012) 1.03
Jak-STAT regulation of male germline stem cell establishment during Drosophila embryogenesis. Dev Biol (2009) 1.03
Transcriptional targets of Drosophila JAK/STAT pathway signalling as effectors of haematopoietic tumour formation. EMBO Rep (2010) 0.99
Mosquito immunity against arboviruses. Viruses (2014) 0.99
The mosquito microbiota influences vector competence for human pathogens. Curr Opin Insect Sci (2014) 0.99
Malignant Drosophila tumors interrupt insulin signaling to induce cachexia-like wasting. Dev Cell (2015) 0.97
The Drosophila cyst stem cell lineage: Partners behind the scenes? Spermatogenesis (2012) 0.96
Multipotent stem cells in the Malpighian tubules of adult Drosophila melanogaster. J Exp Biol (2009) 0.96
Evolution and spermatogenesis. Philos Trans R Soc Lond B Biol Sci (2010) 0.96
Regulation of stem cells by intersecting gradients of long-range niche signals. Dev Cell (2012) 0.95
Negative regulation of Drosophila JAK-STAT signalling by endocytic trafficking. J Cell Sci (2010) 0.94
X-linked variation in immune response in Drosophila melanogaster. Genetics (2009) 0.94
A small-molecule compound identified through a cell-based screening inhibits JAK/STAT pathway signaling in human cancer cells. Mol Cancer Ther (2008) 0.92
Characterization of a dominant-active STAT that promotes tumorigenesis in Drosophila. Dev Biol (2010) 0.92
The Drosophila JAK-STAT pathway in blood cell formation and immunity. JAKSTAT (2013) 0.91
The epigenetic regulator G9a mediates tolerance to RNA virus infection in Drosophila. PLoS Pathog (2015) 0.91
Glypicans regulate JAK/STAT signaling and distribution of the Unpaired morphogen. Development (2012) 0.89
Cytokine signaling through the JAK/STAT pathway is required for long-term memory in Drosophila. Proc Natl Acad Sci U S A (2011) 0.88
Organogenesis and tumorigenesis: insight from the JAK/STAT pathway in the Drosophila eye. Dev Dyn (2010) 0.88
Regulation of proliferation, cell competition, and cellular growth by the Drosophila JAK-STAT pathway. JAKSTAT (2013) 0.88
An efficient approach to isolate STAT regulated enhancers uncovers STAT92E fundamental role in Drosophila tracheal development. Dev Biol (2010) 0.88
Of flies, mice, and men: evolutionarily conserved tissue damage responses and aging. Dev Cell (2015) 0.86
Aedes aegypti ML and Niemann-Pick type C family members are agonists of dengue virus infection. Dev Comp Immunol (2013) 0.86
Signal transduction pathways, intrinsic regulators, and the control of cell fate choice. Biochim Biophys Acta (2012) 0.86
Local signaling within stem cell niches: insights from Drosophila. Curr Opin Cell Biol (2012) 0.86
JAK/STAT pathway dysregulation in tumors: a Drosophila perspective. Semin Cell Dev Biol (2014) 0.86
During Drosophila disc regeneration, JAK/STAT coordinates cell proliferation with Dilp8-mediated developmental delay. Proc Natl Acad Sci U S A (2015) 0.85
MS-1020 is a novel small molecule that selectively inhibits JAK3 activity. Br J Haematol (2009) 0.85
Drosophila SOCS Proteins. J Signal Transduct (2011) 0.84
Essential roles for stat92E in expanding and patterning the proximodistal axis of the Drosophila wing imaginal disc. Dev Biol (2013) 0.83
Localised JAK/STAT pathway activation is required for Drosophila wing hinge development. PLoS One (2013) 0.83
Drosophila SOCS36E negatively regulates JAK/STAT pathway signaling via two separable mechanisms. Mol Biol Cell (2013) 0.83
Drosophila glypicans Dally and Dally-like are essential regulators for JAK/STAT signaling and Unpaired distribution in eye development. Dev Biol (2013) 0.82
The Drosophila melanogaster host model. J Oral Microbiol (2012) 0.82
Socs36E attenuates STAT signaling to optimize motile cell specification in the Drosophila ovary. Dev Biol (2013) 0.82
Identification and characterization of five transcription factors that are associated with evolutionarily conserved immune signaling pathways in the schistosome-transmitting snail Biomphalaria glabrata. Mol Immunol (2011) 0.82
Evidence for tissue-specific Jak/STAT target genes in Drosophila optic lobe development. Genetics (2013) 0.82
The 'ubiquitous' reality of vector immunology. Cell Microbiol (2013) 0.82
Control of tissue morphology by Fasciclin III-mediated intercellular adhesion. Development (2013) 0.81
Functions of the Drosophila JAK-STAT pathway: Lessons from stem cells. JAKSTAT (2012) 0.81
JAK/STAT signaling is required for hinge growth and patterning in the Drosophila wing disc. Dev Biol (2013) 0.81
Drosophila TIEG is a modulator of different signalling pathways involved in wing patterning and cell proliferation. PLoS One (2011) 0.81
Drosophila as a model for antiviral immunity. World J Biol Chem (2010) 0.81
The Drosophila JAK-STAT pathway. JAKSTAT (2013) 0.80
Methotrexate Is a JAK/STAT Pathway Inhibitor. PLoS One (2015) 0.79
What does it take to evolve an enhancer? A simulation-based study of factors influencing the emergence of combinatorial regulation. Genome Biol Evol (2015) 0.79
Benzoxathiol derivative BOT-4-one suppresses L540 lymphoma cell survival and proliferation via inhibition of JAK3/STAT3 signaling. Exp Mol Med (2011) 0.79
Proteomic analysis of Daphnia magna hints at molecular pathways involved in defensive plastic responses. BMC Genomics (2014) 0.79
The RNA-binding proteins FMR1, rasputin and caprin act together with the UBA protein lingerer to restrict tissue growth in Drosophila melanogaster. PLoS Genet (2013) 0.79
Drosophila RISC component VIG and its homolog Vig2 impact heterochromatin formation. PLoS One (2009) 0.79
Diverse tumor pathology due to distinctive patterns of JAK/STAT pathway activation caused by different Drosophila polyhomeotic alleles. Genetics (2011) 0.79
Slowed aging during reproductive dormancy is reflected in genome-wide transcriptome changes in Drosophila melanogaster. BMC Genomics (2016) 0.79
The genome of the crustacean Parhyale hawaiensis, a model for animal development, regeneration, immunity and lignocellulose digestion. Elife (2016) 0.78
Engineered Aedes aegypti JAK/STAT Pathway-Mediated Immunity to Dengue Virus. PLoS Negl Trop Dis (2017) 0.78
GalNAc/Gal-binding Rhizoctonia solani agglutinin has antiproliferative activity in Drosophila melanogaster S2 cells via MAPK and JAK/STAT signaling. PLoS One (2012) 0.78
Identification of JAK/STAT signalling components by genome-wide RNA interference. Nature (2005) 2.90
Characterisation of Upd2, a Drosophila JAK/STAT pathway ligand. Dev Biol (2005) 1.64
A sensitized genetic screen to identify novel regulators and components of the Drosophila janus kinase/signal transducer and activator of transcription pathway. Genetics (2003) 1.63
Cloning and expression of Drosophila SOCS36E and its potential regulation by the JAK/STAT pathway. Mech Dev (2002) 1.30
Opposing roles for Drosophila JAK/STAT signalling during cellular proliferation. Oncogene (2005) 1.16
Differential activities of the Drosophila JAK/STAT pathway ligands Upd, Upd2 and Upd3. Cell Signal (2011) 1.12
Mutational analysis reveals separable DNA binding and trans-activation of Drosophila STAT92E. Cell Signal (2005) 1.07
Identification of JAK/STAT pathway regulators--insights from RNAi screens. Semin Cell Dev Biol (2008) 1.06
Plasticity of Drosophila Stat DNA binding shows an evolutionary basis for Stat transcription factor preferences. EMBO Rep (2008) 1.00
Ken & barbie selectively regulates the expression of a subset of Jak/STAT pathway target genes. Curr Biol (2006) 1.00
Transcriptional targets of Drosophila JAK/STAT pathway signalling as effectors of haematopoietic tumour formation. EMBO Rep (2010) 0.99
Negative regulation of Drosophila JAK-STAT signalling by endocytic trafficking. J Cell Sci (2010) 0.94
Identification of Drosophila genes modulating Janus kinase/signal transducer and activator of transcription signal transduction. Genetics (2005) 0.89
Unphosphorylated STATs go nuclear. Curr Opin Genet Dev (2008) 0.89
JAK/STAT signalling in Drosophila controls cell motility during germ cell migration. Dev Dyn (2006) 0.86
Drosophila SOCS Proteins. J Signal Transduct (2011) 0.84
Localised JAK/STAT pathway activation is required for Drosophila wing hinge development. PLoS One (2013) 0.83
Drosophila SOCS36E negatively regulates JAK/STAT pathway signaling via two separable mechanisms. Mol Biol Cell (2013) 0.83
Control of tissue morphology by Fasciclin III-mediated intercellular adhesion. Development (2013) 0.81
Advances in genome-wide RNAi cellular screens: a case study using the Drosophila JAK/STAT pathway. BMC Genomics (2012) 0.81
Gα73B is a downstream effector of JAK/STAT signalling and a regulator of Rho1 in Drosophila haematopoiesis. J Cell Sci (2013) 0.79
Modulation of human JAK-STAT pathway signaling by functionally conserved regulators. JAKSTAT (2012) 0.78
Simplified Insertion of Transgenes Onto Balancer Chromosomes via Recombinase-Mediated Cassette Exchange. G3 (Bethesda) (2012) 0.76
Designing RNAi screens to identify JAK/STAT pathway components. Methods Mol Biol (2013) 0.76
Matters of the heart. JAKSTAT (2012) 0.75