| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
The p53 pathway.
|
J Pathol
|
1999
|
6.79
|
|
2
|
The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice.
|
Cancer Res
|
1994
|
3.28
|
|
3
|
A comparison of immunohistochemical markers of cell proliferation with experimentally determined growth fraction.
|
J Pathol
|
1991
|
2.71
|
|
4
|
Lassa fever in the United States. Investigation of a case and new guidelines for management.
|
N Engl J Med
|
1990
|
2.57
|
|
5
|
Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer.
|
Br J Cancer
|
1991
|
2.52
|
|
6
|
Detection of the Ki-67 antigen in fixed and wax-embedded sections with the monoclonal antibody MIB1.
|
Histopathology
|
1993
|
2.52
|
|
7
|
p53 in tumour pathology: can we trust immunohistochemistry?--Revisited!
|
J Pathol
|
1994
|
2.41
|
|
8
|
The assessment of proliferating cell nuclear antigen (PCNA) immunostaining in primary gastrointestinal lymphomas and its relationship to histological grade, S+G2+M phase fraction (flow cytometric analysis) and prognosis.
|
Histopathology
|
1991
|
2.32
|
|
9
|
Epidermal growth factor (EGF/URO) induces expression of regulatory peptides in damaged human gastrointestinal tissues.
|
J Pathol
|
1990
|
2.29
|
|
10
|
In situ end-labelling detects DNA strand breaks in apoptosis and other physiological and pathological states.
|
J Pathol
|
1993
|
2.07
|
|
11
|
p53 immunostaining as a marker of malignant disease in diagnostic cytopathology.
|
Lancet
|
1991
|
1.95
|
|
12
|
The prohibitin family of mitochondrial proteins regulate replicative lifespan.
|
Curr Biol
|
1997
|
1.86
|
|
13
|
High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers.
|
Proc Natl Acad Sci U S A
|
1997
|
1.81
|
|
14
|
Proliferative index in breast carcinoma determined in situ by Ki67 immunostaining and its relationship to clinical and pathological variables.
|
J Pathol
|
1987
|
1.80
|
|
15
|
Primary malignant lymphoma of the colon and rectum. A histopathological and immunohistochemical analysis of 45 cases with clinicopathological correlations.
|
Histopathology
|
1988
|
1.76
|
|
16
|
Do we really need a higher necropsy rate?
|
Lancet
|
1999
|
1.71
|
|
17
|
Gadd45 is a nuclear cell cycle regulated protein which interacts with p21Cip1.
|
Oncogene
|
1995
|
1.62
|
|
18
|
Transforming growth factor alpha and epidermal growth factor in human pancreatic cancer.
|
J Pathol
|
1991
|
1.58
|
|
19
|
Coupling between gamma irradiation, p53 induction and the apoptotic response depends upon cell type in vivo.
|
J Cell Sci
|
1995
|
1.57
|
|
20
|
Mammalian prohibitin proteins respond to mitochondrial stress and decrease during cellular senescence.
|
Exp Cell Res
|
2001
|
1.57
|
|
21
|
The complexities of proliferating cell nuclear antigen.
|
Histopathology
|
1992
|
1.57
|
|
22
|
Endocrine cells of the human gastrointestinal tract have no proliferative capacity.
|
Histochem J
|
1995
|
1.49
|
|
23
|
The epidermal growth factor receptor in human pancreatic cancer.
|
J Pathol
|
1992
|
1.47
|
|
24
|
Prognostic value of proliferating cell nuclear antigen in gastric carcinoma.
|
J Clin Pathol
|
1991
|
1.46
|
|
25
|
Koch's postulates revisited.
|
J Pathol
|
1991
|
1.46
|
|
26
|
The p53 response to ionising radiation in adult and developing murine tissues.
|
Oncogene
|
1996
|
1.46
|
|
27
|
Ki67--structure, function, and new antibodies.
|
J Pathol
|
1992
|
1.45
|
|
28
|
APC expression in normal human tissues.
|
J Pathol
|
1997
|
1.44
|
|
29
|
Comparison of manual data coding errors in two hospitals.
|
J Clin Pathol
|
1986
|
1.42
|
|
30
|
Sensitive enzyme-linked immunosorbent assay for detection of Clostridium botulinum neurotoxins A, B, and E using signal amplification via enzyme-linked coagulation assay.
|
J Clin Microbiol
|
1993
|
1.41
|
|
31
|
The relevance of antibody concentration to the immunohistological quantification of cell proliferation-associated antigens.
|
Histopathology
|
1993
|
1.40
|
|
32
|
Identification of the antigen recognized by the monoclonal antibody BU31 as lamins A and C.
|
J Pathol
|
1996
|
1.38
|
|
33
|
The p53 tumour suppressor gene.
|
Br J Surg
|
1998
|
1.37
|
|
34
|
Ki-ras oncogene activation in preinvasive pancreatic cancer.
|
Gastroenterology
|
1992
|
1.33
|
|
35
|
New marker of B lymphocytes, MB2: comparison with other lymphocyte subset markers active in conventionally processed tissue sections.
|
J Clin Pathol
|
1987
|
1.30
|
|
36
|
Epithelial proliferation in Barrett's esophagus by proliferating cell nuclear antigen immunolocalization.
|
Gastroenterology
|
1992
|
1.30
|
|
37
|
Expression of the 'dead box' RNA helicase p68 is developmentally and growth regulated and correlates with organ differentiation/maturation in the fetus.
|
J Pathol
|
1998
|
1.23
|
|
38
|
Proliferative activity of cells in the synovium as demonstrated by a monoclonal antibody, Ki67.
|
Rheumatol Int
|
1987
|
1.22
|
|
39
|
Characterization of the expression pattern of p63 alpha and delta Np63 alpha in benign and malignant oral epithelial lesions.
|
Int J Cancer
|
2000
|
1.21
|
|
40
|
Do septins have a role in cancer?
|
Br J Cancer
|
2005
|
1.20
|
|
41
|
Angiotropic large cell lymphoma (ALCL): morphological, immunohistochemical and genotypic studies with analysis of previous reports.
|
Hematol Oncol
|
1989
|
1.18
|
|
42
|
Rapid technique of DNA-DNA in situ hybridisation on formalin fixed tissue sections using microwave irradiation.
|
J Clin Pathol
|
1987
|
1.17
|
|
43
|
Haemangiopericytomas: the prognostic value of immunohistochemical staining with a monoclonal antibody to proliferating cell nuclear antigen (PCNA).
|
Histopathology
|
1991
|
1.17
|
|
44
|
The p53 molecule and its prognostic role in squamous cell carcinomas of the head and neck.
|
J Oral Pathol Med
|
2000
|
1.16
|
|
45
|
MDM2--arbiter of p53's destruction.
|
Trends Biochem Sci
|
1997
|
1.15
|
|
46
|
Regulation of the CYP1A1 promoter in transgenic mice: an exquisitely sensitive on-off system for cell specific gene regulation.
|
J Cell Sci
|
1996
|
1.14
|
|
47
|
Characterization of a panel of novel anti-p21Waf1/Cip1 monoclonal antibodies and immunochemical analysis of p21Waf1/Cip1 expression in normal human tissues.
|
Am J Pathol
|
1996
|
1.12
|
|
48
|
Primary malignant lymphoma of the large intestine complicating chronic inflammatory bowel disease.
|
Histopathology
|
1989
|
1.11
|
|
49
|
Enteroendocrine cell hyperplasia, carcinoid tumours and adenocarcinoma in long-standing ulcerative colitis.
|
Histopathology
|
1986
|
1.10
|
|
50
|
Immunolocalization of fibroblast growth factor receptor 1 and its ligands in human tissues.
|
Lab Invest
|
1993
|
1.10
|
|
51
|
Do aggressive subclones within primary colorectal cancer give rise to liver metastases?
|
Int J Colorectal Dis
|
1989
|
1.10
|
|
52
|
Enzyme-linked immunosorbent assay and enzyme-linked coagulation assay for detection of Clostridium botulinum neurotoxins A, B, and E and solution-phase complexes with dual-label antibodies.
|
J Clin Microbiol
|
1994
|
1.08
|
|
53
|
Clinical utility of the immunocytochemical detection of p53 protein in cytological specimens.
|
Cancer Res
|
1994
|
1.08
|
|
54
|
Demonstration of DNA damage/repair in individual cells using in situ end labelling: association of p53 with sites of DNA damage.
|
J Pathol
|
1995
|
1.07
|
|
55
|
p53--integrating the complexity.
|
J Pathol
|
1996
|
1.06
|
|
56
|
The location of pKi67 in the outer dense fibrillary compartment of the nucleolus points to a role in ribosome biogenesis during the cell division cycle.
|
J Pathol
|
2000
|
1.05
|
|
57
|
Antigen retrieval by microwave irradiation lowers immunohistological detection thresholds.
|
Histopathology
|
1993
|
1.02
|
|
58
|
Epithelial tumors metastatic to the uterine cervix. A study of 33 cases and review of the literature.
|
Cancer
|
1986
|
1.01
|
|
59
|
Proliferative compartment deregulation in the non-neoplastic colonic epithelium of familial adenomatous polyposis.
|
Gut
|
1995
|
1.01
|
|
60
|
Antibodies to T cell antigen receptor beta chain families detect monoclonal T cell proliferation.
|
Lancet
|
1986
|
1.00
|
|
61
|
Acetone/periodate-lysine-paraformaldehyde (PLP) fixation and improved morphology of cryostat sections for immunohistochemistry.
|
Histopathology
|
1987
|
0.94
|
|
62
|
Expression of basic and acidic fibroblast growth factors and their receptor in normal and atherosclerotic human arteries.
|
Cardiovasc Res
|
1993
|
0.93
|
|
63
|
Transcriptional activation of tyrosinase and TRP-1 by p53 links UV irradiation to the protective tanning response.
|
J Pathol
|
2000
|
0.91
|
|
64
|
The role of the p53 protein in the apoptotic response.
|
Philos Trans R Soc Lond B Biol Sci
|
1994
|
0.90
|
|
65
|
Ki67: from antibody to molecule to understanding?
|
Clin Mol Pathol
|
1995
|
0.90
|
|
66
|
p53 expression is common in malignant mesothelioma.
|
Histopathology
|
1992
|
0.90
|
|
67
|
The biochemical characterization of the DNA binding activity of pKi67.
|
J Pathol
|
2000
|
0.88
|
|
68
|
Control of differentiation in a rectal adenocarcinoma cell line: the role of diffusable and cell-associated factors.
|
J Pathol
|
1991
|
0.88
|
|
69
|
Biochemical characterization of pKi67 with the identification of a mitotic-specific form associated with hyperphosphorylation and altered DNA binding.
|
Exp Cell Res
|
1999
|
0.87
|
|
70
|
Fen1 expression: a novel marker for cell proliferation.
|
J Pathol
|
1998
|
0.87
|
|
71
|
A nude mouse xenograft model of fetal intestine development and differentiation.
|
Development
|
1992
|
0.86
|
|
72
|
Classification of primary gut lymphomas.
|
Lancet
|
1988
|
0.85
|
|
73
|
The Trp53 pathway is induced in vivo by low doses of gamma radiation.
|
Radiat Res
|
2001
|
0.85
|
|
74
|
Extraction of DNA from small sections of frozen tissue with simultaneous histological examination.
|
J Clin Pathol
|
1988
|
0.85
|
|
75
|
Does the p53 up-regulated Gadd45 protein have a role in excision repair?
|
Science
|
1995
|
0.84
|
|
76
|
Malignant lymphoma with eosinophilia of the gastrointestinal tract.
|
Histopathology
|
1987
|
0.83
|
|
77
|
Growth factors and oncogenes in pancreatic cancer.
|
Baillieres Clin Gastroenterol
|
1990
|
0.83
|
|
78
|
Why is p53 protein stabilized in neoplasia? Some answers but many more questions?
|
J Pathol
|
1998
|
0.83
|
|
79
|
A functional model of adult human prostate epithelium. The role of androgens and stroma in architectural organisation and the maintenance of differentiated secretory function.
|
J Cell Sci
|
1992
|
0.83
|
|
80
|
The immunocytochemical detection of p53 protein in cytological specimens: technical considerations.
|
Cytopathology
|
1994
|
0.82
|
|
81
|
Proliferating cell nuclear antigen immunolocalization in gastro-intestinal epithelia.
|
Digestion
|
1991
|
0.82
|
|
82
|
Simultaneous presentation of T- and B-cell malignant lymphoma with bcl-2 gene involvement.
|
Blood
|
1989
|
0.82
|
|
83
|
The association between cell proliferation and apoptosis: studies using the cell cycle-associated proteins Ki67 and DNA polymerase alpha.
|
J Pathol
|
1996
|
0.81
|
|
84
|
An immunochemical analysis of mdm2 expression in human breast cancer and the identification of a growth-regulated cross-reacting species p170.
|
J Pathol
|
1998
|
0.81
|
|
85
|
The yeast two-hybrid system for identifying protein-protein interactions.
|
J Pathol
|
2003
|
0.80
|
|
86
|
Management of localized non-Hodgkin's lymphoma: the experience at St. Bartholomew's Hospital 1972-1985.
|
Hematol Oncol
|
1989
|
0.79
|
|
87
|
The p53 tumour suppressor gene and tumour prognosis: is there a relationship?
|
J Pathol
|
1995
|
0.79
|
|
88
|
Molecular and cellular themes in inflammation and immunology.
|
J Pathol
|
2008
|
0.79
|
|
89
|
Overview of the fibroblast growth factor and receptor families: complexity, functional diversity, and implications for future cardiovascular research.
|
Cardiovasc Res
|
1993
|
0.79
|
|
90
|
Tumour diagnosis.
|
Nature
|
1994
|
0.79
|
|
91
|
Expression of the nuclear membrane protein statin in cycling cells.
|
J Pathol
|
1993
|
0.78
|
|
92
|
The clinical relevance of the p53 tumour suppressor gene.
|
Cytopathology
|
1994
|
0.78
|
|
93
|
Epithelial-mesenchymal interactions can influence the phenotype of carcinoma metastases in the mucosa of the intestine.
|
J Pathol
|
1990
|
0.78
|
|
94
|
Gadd45 mutations are uncommon in human tumour cell lines.
|
Cell Prolif
|
2000
|
0.78
|
|
95
|
A monoclonal antibody (anti-L-35) which reacts with human osteoclasts and cells of the mononuclear phagocyte system.
|
Br J Exp Pathol
|
1988
|
0.78
|
|
96
|
Measuring a cell's response to stress: the p53 pathway.
|
Genome Biol
|
2000
|
0.77
|
|
97
|
Analysis of apoptosis in tissue sections.
|
Methods Mol Biol
|
2001
|
0.77
|
|
98
|
Modeling the growth of Listeria monocytogenes in cured ready-to-eat processed meat products by manipulation of sodium chloride, sodium diacetate, potassium lactate, and product moisture content.
|
J Food Prot
|
2002
|
0.77
|
|
99
|
The fibroblast growth factor and receptor multigene families.
|
J Pathol
|
1993
|
0.77
|
|
100
|
Proliferating cell nuclear antigen (PCNA) and nucleolar organiser regions in Hodgkin's disease: correlation with morphology.
|
J Clin Pathol
|
1993
|
0.77
|
|
101
|
Food safety objective approach for controlling Clostridium botulinum growth and toxin production in commercially sterile foods.
|
J Food Prot
|
2011
|
0.77
|
|
102
|
Cytokeratin and laminin immunostaining in the diagnosis of cutaneous neuro-endocrine (Merkel cell) tumours.
|
Histopathology
|
1986
|
0.77
|
|
103
|
The gut-associated lymphoid tissue and its tumours.
|
Curr Top Pathol
|
1990
|
0.77
|
|
104
|
Challenges to improving health risk communication in the 21st century: a discussion.
|
J Natl Cancer Inst Monogr
|
1999
|
0.77
|
|
105
|
Autonomic hyperreflexia in spinal cord injured patients: trigger mechanism--dressing changes of pressure sores.
|
J Trauma
|
1983
|
0.77
|
|
106
|
Expression of p21waf1/Cip1, MDM2 and p53 in vivo: analysis of cytological preparations.
|
Cytopathology
|
1996
|
0.76
|
|
107
|
Lysophospholipase activity of Ascaris suum-induced mouse peritoneal neutrophils and eosinophils.
|
Microb Pathog
|
1991
|
0.76
|
|
108
|
Lymphoplasmacytoid and small cell centrocytic non-Hodgkin's lymphoma--a retrospective analysis from St Bartholomew's Hospital 1972-1986.
|
Hematol Oncol
|
1989
|
0.76
|
|
109
|
Proliferative activity in Reed-Sternberg cells.
|
Histopathology
|
1994
|
0.76
|
|
110
|
Field change, clonality, and early epithelial cancer: possible lessons from p53.
|
J Pathol
|
1997
|
0.75
|
|
111
|
Cell proliferation in pathology.
|
J Pathol
|
1993
|
0.75
|
|
112
|
Differential diagnosis of metastatic undifferentiated carcinoma.
|
J Clin Pathol
|
1989
|
0.75
|
|
113
|
A Review of Injuries to the Vertebrae occurring in the Royal Air Force.
|
Br Med J
|
1940
|
0.75
|
|
114
|
Immunohistochemistry in lymphoma diagnosis.
|
Br Med J (Clin Res Ed)
|
1986
|
0.75
|
|
115
|
Keratin expression in human tissues and neoplasms: other issues.
|
Histopathology
|
2003
|
0.75
|
|
116
|
Assessment of follicular lymphomas.
|
J Pathol
|
1989
|
0.75
|
|
117
|
Of spots, stripes and muddled thinking!
|
Histopathology
|
1993
|
0.75
|
|
118
|
Angiolymphoid hyperplasia with eosinophilia.
|
J R Soc Med
|
1987
|
0.75
|
|
119
|
Detection of the Ki-67 antigen in fixed and wax-embedded sections with the monoclonal antibody MIB1.
|
Histopathology
|
2002
|
0.75
|
|
120
|
The assessment of proliferating cell nuclear antigen (PCNA)immunostaining in primary gastrointestinal lymphomas and its relationship to histological grade, S + G2 + M phase fraction (flow cytometric analysis) and prognosis.
|
Histopathology
|
2002
|
0.75
|
|
121
|
Simultaneous presentation of B- and T-cell malignant lymphoma.
|
Haematol Blood Transfus
|
1989
|
0.75
|
|
122
|
14;18 translocation in primary intestinal lymphoma: detection by polymerase chain reaction in routinely processed tissue.
|
Histopathology
|
1991
|
0.75
|
|
123
|
Analysis of apoptosis in tissue sections.
|
Methods Mol Med
|
1999
|
0.75
|
|
124
|
Effects of altered cardiac ventricular chamber size on the electrocardiogram and position of the heart.
|
Am J Cardiol
|
1990
|
0.75
|
|
125
|
An inter-observer and intra-observer variability study on the diagnosis of lymph node biopsy specimens.
|
Eur J Cancer
|
1992
|
0.75
|
|
126
|
Paediatric triple lumen catheter.
|
Paediatr Anaesth
|
1995
|
0.75
|
|
127
|
Proliferating trichilemmal cyst occurring on the shin.
|
J Cutan Pathol
|
1986
|
0.75
|
|
128
|
Expression of p53 in reactive mesothelium.
|
Histopathology
|
1993
|
0.75
|
|
129
|
The challenge of p53: linking biochemistry, biology, and patient management.
|
Stem Cells
|
1998
|
0.75
|
|
130
|
Caecal lipomas mimicking colonic angiodysplasia.
|
Br J Radiol
|
1985
|
0.75
|
|
131
|
Plastic embedding of bone marrow biopsies.
|
Histopathology
|
1987
|
0.75
|
|
132
|
Multicentric reticulohistiocytosis. Detailed immunophenotyping confirms macrophage origin.
|
Am J Surg Pathol
|
1990
|
0.75
|
|
133
|
Unification of electromagnetic effects in human retinal receptors with three pigment colour vision.
|
Nature
|
1969
|
0.75
|
|
134
|
Histiocytosis X mimicking recurrent malignant disease: a report of two cases.
|
Clin Radiol
|
1988
|
0.75
|
|
135
|
Classifying primary gut lymphomas.
|
Lancet
|
1988
|
0.75
|
|
136
|
Modified excised teat model for laboratory screening of teat dips.
|
J Dairy Sci
|
1981
|
0.75
|
|
137
|
Carcinoma of the gall bladder metastatic to the cervix. Case report.
|
Br J Obstet Gynaecol
|
1986
|
0.75
|
|
138
|
Langerhan's cell histiocytosis: an unusual case illustrating the value of immunohistochemistry in diagnosis.
|
Histopathology
|
1988
|
0.75
|
|
139
|
Effects of an aromatase inhibitor on thymus and kidney and on oestrogen receptors in female MRL/MP-lpr/lpr mice.
|
Lupus
|
1993
|
0.75
|