Published in Br J Cancer on June 27, 2006
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat Genet (2008) 6.75
Base-excision repair of oxidative DNA damage. Nature (2007) 5.44
Germline MutY human homologue mutations and colorectal cancer: a multisite case-control study. Gastroenterology (2008) 1.69
Germline mutations of the MYH gene in Korean patients with multiple colorectal adenomas. Int J Colorectal Dis (2007) 1.23
A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants. Br J Cancer (2010) 1.11
MUTYH Associated Polyposis (MAP). Curr Genomics (2008) 1.06
Association between monoallelic MUTYH mutation and colorectal cancer risk: a meta-regression analysis. Fam Cancer (2011) 0.97
Recently identified colon cancer predispositions: MYH and MSH6 mutations. Semin Oncol (2007) 0.94
The genetic basis of familial adenomatous polyposis and its implications for clinical practice and risk management. Appl Clin Genet (2015) 0.89
Coexistence of copy number increases of ZNF217 and CYP24A1 in colorectal cancers in a Chinese population. Oncol Lett (2010) 0.83
French experts report on MUTYH-associated polyposis (MAP). Fam Cancer (2012) 0.82
Evidence of linkage to chromosomes 10p15.3-p15.1, 14q24.3-q31.1 and 9q33.3-q34.3 in non-syndromic colorectal cancer families. Eur J Hum Genet (2011) 0.82
MUTYH-associated polyposis (MAP): evidence for the origin of the common European mutations p.Tyr179Cys and p.Gly396Asp by founder events. Eur J Hum Genet (2013) 0.81
In vitro functional effects of XPC gene rare variants from bladder cancer patients. Carcinogenesis (2011) 0.80
Amplifications of NCOA3 gene in colorectal cancers in a Chinese population. World J Gastroenterol (2012) 0.79
Common MUTYH mutations and colorectal cancer risk in multiethnic populations. Fam Cancer (2012) 0.78
MUTYH-associated polyposis (MAP), the syndrome implicating base excision repair in inherited predisposition to colorectal tumors. Front Oncol (2012) 0.78
Undefined familial colorectal cancer. World J Gastrointest Oncol (2009) 0.78
Diagnostic Approach to Hereditary Colorectal Cancer Syndromes. Clin Colon Rectal Surg (2015) 0.78
Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis. Clin Exp Gastroenterol (2011) 0.77
High prevalence of the c.1227_1228dup (p.Glu410GlyfsX43) mutation in Tunisian families affected with MUTYH-associated-polyposis. Fam Cancer (2012) 0.77
Whole Gene Capture Analysis of 15 CRC Susceptibility Genes in Suspected Lynch Syndrome Patients. PLoS One (2016) 0.75
Functional Complementation Assay for 47 MUTYH Variants in a MutY-Disrupted Escherichia Coli Strain. Hum Mutat (2015) 0.75
Association of monoallelic MUTYH mutation among Egyptian patients with colorectal cancer. Fam Cancer (2017) 0.75
Quantifying heterogeneity in a meta-analysis. Stat Med (2002) 83.16
Inherited variants of MYH associated with somatic G:C-->T:A mutations in colorectal tumors. Nat Genet (2002) 7.00
Endogenous mutagens and the causes of aging and cancer. Mutat Res (1991) 2.96
Association between biallelic and monoallelic germline MYH gene mutations and colorectal cancer risk. J Natl Cancer Inst (2004) 2.68
Comprehensive analysis of the contribution of germline MYH variation to early-onset colorectal cancer. Int J Cancer (2004) 2.53
MYH mutations in patients with attenuated and classic polyposis and with young-onset colorectal cancer without polyps. Gastroenterology (2004) 2.35
Germline susceptibility to colorectal cancer due to base-excision repair gene defects. Am J Hum Genet (2005) 2.17
Risk of colorectal cancer in monoallelic and biallelic carriers of MYH mutations: a population-based case-family study. Cancer Epidemiol Biomarkers Prev (2006) 1.46
Proportion and phenotype of MYH-associated colorectal neoplasia in a population-based series of Finnish colorectal cancer patients. Am J Pathol (2003) 1.38
Role of inherited defects of MYH in the development of sporadic colorectal cancer. Genes Chromosomes Cancer (2004) 1.26
Colorectal cancer risk in individuals with biallelic or monoallelic mutations of MYH. Int J Cancer (2005) 1.16
Germline mutations in the MYH gene in Swedish familial and sporadic colorectal cancer. Genet Test (2005) 1.10
Inherited variants in MYH are unlikely to contribute to the risk of lung carcinoma. Hum Genet (2003) 1.08
Allele frequencies of single nucleotide polymorphisms (SNPs) in 40 candidate genes for gene-environment studies on cancer: data from population-based Japanese random samples. J Hum Genet (2003) 0.97
A novel splice-site variant of the base excision repair gene MYH is associated with production of an aberrant mRNA transcript encoding a truncated MYH protein not localized in the nucleus. Carcinogenesis (2004) 0.93
Re: Association between biallelic and monoallelic germline MYH gene mutations and colorectal cancer risk. J Natl Cancer Inst (2005) 0.89
Puerperal thromboembolism and suppression of lactation. Lancet (1967) 8.22
Integrated care pathways. BMJ (1998) 6.14
Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients. Nat Med (1996) 4.87
Bronchitis in two integrated steel works. I. Ventilatory capacity, age, and physique of non-bronchitic men. Br J Prev Soc Med (1968) 4.75
Double-blind randomised controlled trial of folate treatment before conception to prevent recurrence of neural-tube defects. Br Med J (Clin Res Ed) (1981) 4.12
Natural family planning in the 1990s. Lancet (1995) 3.97
Obstetric practice and outcome of pregnancy in Cardiff residents 1965-73. Br Med J (1976) 3.54
Emphysema in coal workers' pneumoconiosis. Br Med J (1970) 3.48
Cancer risk associated with germline DNA mismatch repair gene mutations. Hum Mol Genet (1997) 3.41
Environmental epidemiology. IV. Chronic respiratory disease in an industrial town: a nine-year follow-up study. Preliminary report. Am J Public Health Nations Health (1968) 3.33
The magnitude of mortality from acute respiratory infections in children under 5 years in developing countries. World Health Stat Q (1992) 3.14
Genetic instability occurs in the majority of young patients with colorectal cancer. Nat Med (1995) 3.07
Gastric emptying in health and in gastroduodenal disease. Gastroenterology (1968) 2.75
TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres. Gut (2011) 2.75
Few Canadian hospitals qualify for "Baby Friendly" designation by promoting breast-feeding: survey. CMAJ (1995) 2.70
Trend analysis of socioeconomic differentials in deaths from injury in childhood in Scotland, 1981-95. BMJ (1999) 2.59
Dextran 70 in prophylaxis of thromboembolic disease after surgery: a clinically oriented randomized double-blind trial. Br Med J (1975) 2.51
Evaluation of a computerized field data collection system for health surveys. Bull World Health Organ (1991) 2.51
Screening for people with a family history of colorectal cancer. BMJ (1997) 2.50
Development and technical basis of simplified guidelines for emergency triage assessment and treatment in developing countries. WHO Integrated Management of Childhood Illness (IMCI) Referral Care Project. Arch Dis Child (1999) 2.49
National study of microphthalmia, anophthalmia, and coloboma (MAC) in Scotland: investigation of genetic aetiology. J Med Genet (2002) 2.39
Indian hedgehog activates hematopoiesis and vasculogenesis and can respecify prospective neurectodermal cell fate in the mouse embryo. Development (2001) 2.33
Comparison of the effects of dexamphetamine and 1-benzylpiperazine in former addicts. Eur J Clin Pharmacol (1973) 2.31
Pulmonary disability in coal workers' pneumoconiosis. Br Med J (1972) 2.29
Increased factor IX levels in puerperium during administration of diethylstilboestrol. Br Med J (1968) 2.29
APC mutations in colorectal tumors with mismatch repair deficiency. Proc Natl Acad Sci U S A (1996) 2.18
Asymptomatic significant bacteriuria in the non-pregnant woman. I. Description of a population. Br Med J (1969) 2.03
Parental confidence in measles, mumps and rubella vaccine: evidence from vaccine coverage and attitudinal surveys. Br J Gen Pract (2002) 2.00
Genetic epidemiological studies of eastern Adriatic Island isolates, Croatia: objective and strategies. Coll Antropol (1999) 1.98
Use of oxytocin and incidence of neonatal jaundice. Br Med J (1975) 1.96
Imported malaria in the UK: advice given by general practitioners to British residents travelling to malaria endemic areas. J R Coll Gen Pract (1987) 1.96
GPs' views on their role in cancer genetics services and current practice. Fam Pract (1999) 1.94
Trans activation of plasmid-borne promoters by adenovirus and several herpes group viruses. Nucleic Acids Res (1984) 1.93
Inbreeding and risk of late onset complex disease. J Med Genet (2003) 1.92
Accuracy of reporting of family history of colorectal cancer. Gut (2004) 1.92
Potential interventions for the prevention of childhood pneumonia in developing countries: a systematic review. Bull World Health Organ (1995) 1.88
Asymptomatic significant bacteriuria in the non-pregnant woman. II. Response to treatment and follow-up. Br Med J (1969) 1.82
The pattern of anaesthesia in a general hospital. Br J Anaesth (1967) 1.82
Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes. Am J Hum Genet (2001) 1.81
Resting pulse rate in marathon runners. Br Med J (Clin Res Ed) (1982) 1.71
Estimating human inbreeding coefficients: comparison of genealogical and marker heterozygosity approaches. Ann Hum Genet (2006) 1.68
Etiology of acute lower respiratory tract infections in Gambian children: I. Acute lower respiratory tract infections in infants presenting at the hospital. Pediatr Infect Dis J (1991) 1.66
A study of the Huntington's disease associated trinucleotide repeat in the Scottish population. J Med Genet (1993) 1.66
Increased risk of recurrence of pregnancies complicated by fetal neural tube defects in mothers receiving poor diets, and possible benefit of dietary counselling. Br Med J (1980) 1.63
COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer. Br J Cancer (2009) 1.62
Indoor air pollution exposure and lower respiratory infections in young Gambian children. Int J Epidemiol (1991) 1.62
Bronchitis in two integrated steel works. 3. Respiratory symptoms and ventilatory capacity related to atmospheric pollution. Br J Ind Med (1970) 1.60
Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60
The epidemiology of rhegmatogenous retinal detachment: geographical variation and clinical associations. Br J Ophthalmol (2009) 1.60
Potential interventions for the prevention of childhood pneumonia in developing countries: improving nutrition. Am J Clin Nutr (1999) 1.57
Etiology of acute lower respiratory tract infections in Gambian children: II. Acute lower respiratory tract infection in children ages one to nine years presenting at the hospital. Pediatr Infect Dis J (1991) 1.57
The future of breast and ovarian cancer clinics. BMJ (1995) 1.57
Controlled trial of azathioprine in Crohn's disease. Lancet (1971) 1.56
Evidence for genetic heterogeneity in hereditary hydronephrosis caused by pelvi-ureteric junction obstruction, with one locus assigned to chromosome 6p. Hum Genet (1992) 1.53
Malaria in a peri-urban area of The Gambia. Ann Trop Med Parasitol (1990) 1.52
Whole-gene APC deletions cause classical familial adenomatous polyposis, but not attenuated polyposis or "multiple" colorectal adenomas. Proc Natl Acad Sci U S A (2002) 1.51
Strengthening clinical cancer research in the United Kingdom. Br J Cancer (2011) 1.50
Mismatch repair genes hMLH1 and hMSH2 and colorectal cancer: a HuGE review. Am J Epidemiol (2002) 1.49
Dentatorubral and pallidoluysian atrophy (DRPLA). Clinical and neuropathological findings in genetically confirmed North American and European pedigrees. Mov Disord (1997) 1.49
The relative roles of advanced glycation, oxidation and aldose reductase inhibition in the development of experimental diabetic nephropathy in the Sprague-Dawley rat. Diabetologia (1995) 1.46
Pilot survey of haemoglobin and plasma urea concentration in a random sample of adults in Wales 1965-66. Br J Prev Soc Med (1968) 1.45
Hematopoietic induction and respecification of A-P identity by visceral endoderm signaling in the mouse embryo. Development (1998) 1.45
Maternal smoking habits and congenital malformations: a population study. Br Med J (1979) 1.43
Changes in the pituitary-testicular system with age. Clin Endocrinol (Oxf) (1976) 1.43
Indomethacin in rheumatoid arthritis: an evaluation of its anti-inflammatory and side effects. Br Med J (1967) 1.42
Observation of a centrality-dependent dijet asymmetry in lead-lead collisions at sqrt[S(NN)] =2.76 TeV with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.41
Adjuvant distal arteriovenous shunt with femorotibial bypass for critical ischaemia. Br J Surg (1983) 1.39
Measurement of dijet azimuthal decorrelations in pp collisions at sqrt(s)=7 TeV. Phys Rev Lett (2011) 1.39
Significance of irregular opacities in the radiology of coalworkers' pneumoconiosis. Br J Ind Med (1974) 1.37
Determination of the strange-quark density of the proton from ATLAS measurements of the W→ℓν and Z→ℓℓ cross sections. Phys Rev Lett (2012) 1.34
Simple clinical signs for diagnosis of acute lower respiratory infections. Lancet (1988) 1.34
Analysis of genetic and phenotypic heterogeneity in juvenile polyposis. Gut (2000) 1.34
Search for new particles in two-jet final states in 7 TeV proton-proton collisions with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.32
Association studies on 11 published colorectal cancer risk loci. Br J Cancer (2010) 1.31
A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila. Mol Psychiatry (2011) 1.30
Hereditary haemorrhagic telangiectasia: a questionnaire based study to delineate the different phenotypes caused by endoglin and ALK1 mutations. J Med Genet (2003) 1.28
Observation of associated near-side and away-side long-range correlations in sqrt[s(NN)]=5.02 TeV proton-lead collisions with the ATLAS detector. Phys Rev Lett (2013) 1.27
Pertussis immunisation and control in England and Wales, 1957 to 2012: a historical review. Euro Surveill (2013) 1.27
Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases. Hum Mol Genet (1998) 1.26
Population carrier frequency of hMSH2 and hMLH1 mutations. Br J Cancer (2000) 1.23
Referrals of women with a family history of breast cancer from primary care to cancer genetics services in South East Scotland. Br J Cancer (2003) 1.21
Search for dark matter candidates and large extra dimensions in events with a photon and missing transverse momentum in pp collision data at sqrt[s]=7 TeV with the ATLAS detector. Phys Rev Lett (2013) 1.19
A candidate spermatogenesis gene on the mouse Y chromosome is homologous to ubiquitin-activating enzyme E1. Nature (1991) 1.18
A survey of vaccine coverage and antibiotic prophylaxis in splenectomised patients in Scotland. J Clin Pathol (2002) 1.17
Relation between progressive massive fibrosis, emphysema, and pulmonary dysfunction in coalworkers' pneumoconiosis. Br J Ind Med (1981) 1.16
Cost-effectiveness of using prognostic information to select women with breast cancer for adjuvant systemic therapy. Health Technol Assess (2006) 1.15
Renpenning syndrome comes into focus. Am J Med Genet A (2005) 1.15
Patient satisfaction with two different models of cancer genetic services in south-east Scotland. Br J Cancer (2004) 1.15
Search for a supersymmetric partner to the top quark in final states with jets and missing transverse momentum at sqrt[s] = 7 TeV with the ATLAS detector. Phys Rev Lett (2012) 1.13
Helper functions of antigen-induced specific and autoreactive T cell colonies. J Mol Cell Immunol (1984) 1.12
A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants. Br J Cancer (2010) 1.11